Regulation of platelet heparanase during inflammation: Role of pH and proteinases

Journal of Cellular Physiology

Volumn 175, Issue 3, 1998, Pages 255-267

  Ihrcke, Nathan S ^a   Parker, William ^a   Reissner, Kathryn J ^a   Platt, Jeffrey L ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARANASE;

ARTICLE; CELL PH; ENZYME DEGRADATION; HUMAN; HUMAN CELL; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD COAGULATION FACTORS; BLOOD PLATELETS; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME STABILITY; GLUCURONIDASE; GLYCOSIDE HYDROLASES; HEPARITIN SULFATE; HUMANS; HYDROGEN-ION CONCENTRATION; INFLAMMATION; MOLECULAR WEIGHT; PEPTIDES; SERINE ENDOPEPTIDASES; SODIUM CHLORIDE; SWINE;

EID: 0031966911     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199806)175:3<255::AID-JCP3>3.0.CO;2-N     Document Type: Article

References (41)

1. Abrahamsson, T., Brandt, U., Marklund, S.L., and Sjoquist, P. (1992) Vascular bound recombinant extracellular superoxide dismutase type C protects against the detrimental effects of superoxide radicals on endothelium-dependent arterial relaxation. Circ. Res., 70:264-271.
2. Caughman, G.B., Boackle, R.J., and Vesely, J. (1992) A postulated mechanism for heparin's potentiation of C1 inhibitor function. Mol. Immunol., 19:287-295.
3. Copley, A.L., and Witte, S. (1976) On physiological microthromboembolization as the primary platelet function: elimination of invaded particles from the circulation and its pathogenic significance. Thromb. Res., 8:251-262.
4. Geller, R.L., Ihrcke, N.S., Maines, J., Lindman, B.J., and Platt, J.L. (1993) Loss of heparan sulfate proteoglycan as a manifestation of cellular immunity in vivo and in vitro. Transplant. Proc., 25:144-145.
5. Gilat, D., Hershkoviz, R., Goldkorn, I., Cahalon, L., Korner, G., Vlodavsky, I., and Lider, O. (1995) Molecular behavior adapts to context: heparanase functions as an extracellular matrix-degrading enzyme or as a T-cell adhesion molecule, depending on the local pH. J. Exp. Med., 181:1929-1934.
6. Godder, K., Vlodavsky, I., Eldor, A., Weksler, B.B., Haimomivitz-Friedman, A., and Fuks, A. (1991) Heparanase activity in cultured endothelial cells. J. Cell. Physiol., 148:274-289.
7. Haimovitz-Friedman, A., Falcone, D.J., Eldor, A., Schmirrmacher, V., Vlodavsky, I., and Fuks, Z. (1991) Activation of platelet heparitinase by tumor cell-derived factors. Blood, 78:789-796.
8. Holzknecht, Z.E., and Platt, J.L. (1995) Identification of porcine endothelial cell membrane antigens recognized by human xenoreactive antibodies. J. Immunol., 154:4565-4575.
9. Hoogewerf, A.J., Leone, J.W., Reardon, I.M., Howe, W.J., Asa, D., Heinrikson, R.L., and Ledbetter, S.R. (1995) CXC chemokines connective tissue activating peptide-III and neutrophil activating peptide-2 are heparin/heparan sulfate-degrading enzymes. J. Biol. Chem., 270:3268-3277.
10. Ihrcke, N.S., and Platt, J.L. (1996) Shedding of heparan sulfate proteoglycan by stimulated endothelial cells: Evidence for proteolysis of cell surface molecules. J. Cell. Physiol., 168:625-637.
11. Ihrcke, N.S., Wrenshall, L.E., Lindman, B.J., and Platt, J.L. (1993) Role of heparan sulfate in immune system-blood vessel interactions. Immunol. Today, 14:500-505.
12. Ishai-Michaeli, R., Eldor, A., and Vlodavsky, I. (1990) Heparanase activity expressed by platelets, neutrophils, and lymphoma cells releases active fibroblast growth factor from the extracellular matrix. Cell Regul., 1:833-842.
13. Kanwar, Y.S., Linker, A., and Farquhar, M.G. (1980) Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion. J. Cell Biol., 86:688-693.
14. Keren, Z., Leland, F., Nakajima, M., and LeGrue, S.J. (1989) Inhibition of experimental metastasis and extracellular matrix degradation by butanol extracts from b16-f1 murine melanoma. Cancer Res., 49:295-300.
15. Key, N.S., Platt, J.L., and Vercellotti, G.M. (1992) Vascular endothelial cell proteoglycans are susceptible to cleavage by neutrophils. Arterioscler. Thromb., 12:836-842.
16. Lider, O., Cahalon, L., Gilat, D., Hershkoviz, R., Siegel, D., Margalit, R., Shoseyov, O., and Cohen, I.R (1995) A disaccharide that inhibits tumor necrosis factor α is formed from the extracellular matrix by the enzyme heparanase. Proc. Natl. Acad. Sci. U.S.A., 92:5037-5041.
17. Marcum, J.A., and Rosenberg, R.D. (1989) Role of endothelial cell surface heparin-like polysaccharides. Ann. N.Y. Acad. Sci., 556:81-94.
18. Marcum, J.A., Reilly, C.F., and Rosenberg, R.D. (1987) Heparan sulfate species and blood vessel wall function. In: Biology of Proteoglycans. T.N. Wight and R.P. Mecham, eds. Academic Press, Orlando, FL, pp. 301-343.
19. Nakajima, M., Irimura, T., and Nicolson, G.L. (1988) Heparanases and tumor metastasis. J. Cell. Biochem., 36:157-167.
20. Nakajima, M., DeChavigny, A., Johnson, C.E., Hamada, J., Stein, C.A., and Nicolson, G.L. (1991) Suramin: a potent inhibitor of melanoma heparanase and invasion. J. Biol. Chem., 266:9661-9666.
21. Nakazono, K., Watanabe, N., Matsuno, K., Sasaki, J., Sato, T., and Inoue, M. (1991) Does superoxide underlie the pathogenesis of hypertension? Proc. Natl. Acad. Sci. U.S.A., 88:10045-10048.
22. Oldberg, A., Heldin, C., Wasteson, A., Busch, C., and Hook, M. (1980) Characterization of a platelet endoglycosidase degrading heparin-like polysaccharides. Biochemistry, 19:5755-5762.
23. Oosta, G.M., Favreau, L.V., Beeler, D.L., and Rosenberg, R.D. (1982) Purification and properties of human platelet heparitinase. J. Biol. Chem., 257:11249-11255.
24. Platt, J.L., Vercellotti, G.M., Lindman, B.J., Oegema, T.R., Jr., Bach, F.H., and Dalmasso, A.P. (1990) Release of heparan sulfate from endothelial cells: Implications for pathogenesis of hyperacute rejection. J. Exp. Med., 171:1363-1368.
25. Pober, J.S., and Cotran, R.S. (1990) Cytokines and endothelial cell biology. Physiol. Rev., 70:427-451.
26. Redini, F., Tixier, J., Petitou, M., Choay, J., Robert, L., and Hornebeck, W. (1988) Inhibition of leucocyte elastase by heparin and its derivatives. Biochem. J., 252:515-519.
27. Ryan, U.S., and Maxwell, G. (1986) Isolation, culture and subculture of endothelial cells: mechanical methods. J. Tissue Culture Methods, 10:3-5.
28. Sasisekharan, R., Moses, M.A., Nugent, M.A., Cooney, C.L., and Langer, R. (1994) Heparinase inhibits neovascularization. Proc. Natl. Acad. Sci. U.S.A., 91:1524-1528.
29. Stevens, R.B., Wang, Y.L., Kaji, H., Lloveras, J., Dalmasso, A.B., Bach, F.H., Rubinstein, P., Sutherland, D.E.R., and Platt, J.L. (1993) Administration of nonanticoagulant heparin inhibits the loss of glycosaminoglycans from xenogeneic cardiac grafts and prolongs graft survival. Transplant. Proc., 25:382.
30. Tanaka, Y., Adams, D., and Shaw, S. (1993) Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes. Immunol. Today, 14:111-115.
31. Thundberg, L., Backstrom, G., Wasteson, A., Robinson, H.C., Ogren, S., and Lindahl, U. (1982) Enzymatic depolymerization of heparin-related polysaccharides. J. Biol. Chem., 257:10278-10282.
32. Vlodavsky, I., Eldor, A., Haimovitz-Friedman, A., Ishai-Michaeli, R., Lider, O., Naparstek, Y., Cohen, I.R., and Fuks, Z. (1992) Expression of heparanase by platelets and circulating cells of the immune system: Possible involvement in diapedesis and extravasation. Invasion Metastasis, 12:112-127.
33. Wasteson, A., Glimelius, B., Busch, C., Westermark, B., Heldin, C., and Norling, B. (1977) Effect of platelet endoglycosidase on cell surface associated heparan sulphate of human cultured endothelial and glial cells. Thromb. Res., 11:309-321.
34. Webb, L.M.C., Ehrengruber, M.U., Clark-Lewis, I., Baggiolini, M., and Rot, A. (1993) Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin-8. Proc. Natl. Acad. Sci. U. S. A., 90:7158-7162.
35. Weiler, J.M., and Linhardt, R.J. (1991) Antithrombin III regulates complement activity in vitro. J. Immunol., 146:3889-3894.
36. Wike-Hooley, J.L., Haveman, J., and Reinhold, H.S. (1984) The relevance of tumour pH to the treatment of malignant disease. Radiother. Oncol., 2:343-366.
37. Williams, T.J., Brain, S.D., Hellewell, P.G., Jose, P.J., Nourshargh, S., and Rampart, M. (1988) Alterations in microvascular permeability induced by products released during inflammation. In: Mechanisms in Asthma: Pharmacology, Physiology and Management. Alan R. Liss Inc., New York, pp. 55-69.
38. Wrenshall, L.E., Cerra, F.B., Carlson, A., Bach, F.H., and Platt, J.L. (1991) Regulation of murine splenocyte responses by heparan sulfate. J. Immunol., 147:455-459.
39. Wrenshall, L.E., Carlson, A., Cerra, F.B., and Platt, J.L. (1994) Modulation of cytolytic T-cell responses by heparan sulfate. Transplantation, 57:1087-1094.
40. Wrenshall, L.E., Cerra, F.B., Singh, R.K., and Platt, J.L. (1995) Heparan sulfate initiates signals in murine macrophages leading to divergent biological outcomes. J. Immunol., 154:871-880.
41. Yahalom, J., Eldor, A., Fuks, Z., and Vlodavsky, I. (1984) Degradation of sulfated proteoglycans in the subendothelial extracellular matrix by human platelet heparitinase. J. Clin. Invest., 74:1842-1849.