Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2

Nature Medicine

Volumn 4, Issue 6, 1998, Pages 691-697

  Kato, Masato ^a,d   Wang, Huiming ^a,e   Kainulainen, Varpu ^a   Fitzgerald, Marilyn L ^a   Ledbetter, Steven ^b   Ornitz, David M ^c   Bernfield, Merton ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b GENZYME CORPORATION   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF OTAGO   (New Zealand)

^e Trancell Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; HEPARANASE; SYNDECAN;

ARTICLE; GENE CONTROL; HUMAN; MITOGENICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; WOUND; WOUND HEALING;

BINDING SITES; EXUDATES AND TRANSUDATES; FIBRINOLYTIC AGENTS; FIBROBLAST GROWTH FACTOR 2; GLUCURONIDASE; GLYCOSIDE HYDROLASES; HEPARIN; HEPARITIN SULFATE; HUMANS; MEMBRANE GLYCOPROTEINS; MITOGENS; OLIGOSACCHARIDES; PROTEIN BINDING; PROTEOGLYCANS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, FIBROBLAST GROWTH FACTOR; SOLUBILITY; SYNDECAN-1; SYNDECANS; WOUNDS AND INJURIES;

EID: 0031749471     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0698-691     Document Type: Article

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