메뉴 건너뛰기




Volumn 35, Issue 8, 2014, Pages 7335-7342

Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer

Author keywords

Cancer therapeutics; Epithelial to mesenchymal transition; Metastasis; Slug; Snail; Twist; Zeb

Indexed keywords

HOMEODOMAIN PROTEIN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TWIST; ZEB1 PROTEIN, HUMAN;

EID: 84922395039     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1007/s13277-014-2163-y     Document Type: Review
Times cited : (240)

References (101)
  • 1
    • 80053074082 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in breast cancer progression and metastasis
    • COI: 1:CAS:528:DC%2BC3MXhtlylt7rE, PID: 21880181
    • Wang Y, Zhou BP. Epithelial-mesenchymal transition in breast cancer progression and metastasis. Chin J Cancer. 2011;30:603–11.
    • (2011) Chin J Cancer , vol.30 , pp. 603-611
    • Wang, Y.1    Zhou, B.P.2
  • 2
    • 84882400809 scopus 로고    scopus 로고
    • EMT transcription factors: implication in osteosarcoma
    • PID: 23975634
    • Yang G, Yuan J, Li K. EMT transcription factors: implication in osteosarcoma. Med Oncol. 2013;30:697.
    • (2013) Med Oncol , vol.30 , pp. 697
    • Yang, G.1    Yuan, J.2    Li, K.3
  • 3
    • 4043052971 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: twist in development and metastasis
    • COI: 1:CAS:528:DC%2BD2cXmslKrs7w%3D, PID: 15294153
    • Kang Y, Massagué J. Epithelial-mesenchymal transitions: twist in development and metastasis. Cell. 2004;118:277–9.
    • (2004) Cell , vol.118 , pp. 277-279
    • Kang, Y.1    Massagué, J.2
  • 4
    • 84885424897 scopus 로고    scopus 로고
    • Twist: a molecular target in cancer therapeutics
    • COI: 1:CAS:528:DC%2BC3sXhsFKqs7vP
    • Khan MA, Chen HC, Zhang D, Fu J. Twist: a molecular target in cancer therapeutics. Tumor Biol. 2013;34:2497–506.
    • (2013) Tumor Biol , vol.34 , pp. 2497-2506
    • Khan, M.A.1    Chen, H.C.2    Zhang, D.3    Fu, J.4
  • 5
    • 84901236438 scopus 로고    scopus 로고
    • Khan MI, Adhami VM, Lall RK, Sechi M, Joshi DC, Haider OM, et al. YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin. Oncotarget
    • Khan MI, Adhami VM, Lall RK, Sechi M, Joshi DC, Haider OM, et al. YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin. Oncotarget. 2014 Feb 19. (in press).
  • 6
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • COI: 1:CAS:528:DC%2BC3MXjs1Cgtbo%3D, PID: 21436443
    • Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science. 2011;331:1559–64.
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 7
    • 21244437500 scopus 로고    scopus 로고
    • Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
    • PID: 15864483
    • Martin TA, Goyal A, Watkins G, Jiang WG. Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Ann Surg Oncol. 2005;12:488–96.
    • (2005) Ann Surg Oncol , vol.12 , pp. 488-496
    • Martin, T.A.1    Goyal, A.2    Watkins, G.3    Jiang, W.G.4
  • 8
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • PID: 23344542
    • De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer. 2013;13:97–110.
    • (2013) Nat Rev Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 9
    • 84900449511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition—activating transcription factors—multifunctional regulators in cancer
    • PID: 24179606
    • Garg M. Epithelial-mesenchymal transition—activating transcription factors—multifunctional regulators in cancer. World J Stem Cells. 2013;5:188–95.
    • (2013) World J Stem Cells , vol.5 , pp. 188-195
    • Garg, M.1
  • 10
    • 84880257210 scopus 로고    scopus 로고
    • Prognostic value of Twist and E-cadherin in patients with osteosarcoma
    • COI: 1:CAS:528:DC%2BC38XhslCntr3E, PID: 22847601
    • Yin K, Liao Q, He H, Zhong D. Prognostic value of Twist and E-cadherin in patients with osteosarcoma. Med Oncol. 2012;29:3449–55.
    • (2012) Med Oncol , vol.29 , pp. 3449-3455
    • Yin, K.1    Liao, Q.2    He, H.3    Zhong, D.4
  • 11
    • 0037462477 scopus 로고    scopus 로고
    • Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity
    • PID: 12553906
    • Šošić D, Richardson JA, Yu K, Ornitz DM, Olson EN. Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell. 2003;112:169–80.
    • (2003) Cell , vol.112 , pp. 169-180
    • Šošić, D.1    Richardson, J.A.2    Yu, K.3    Ornitz, D.M.4    Olson, E.N.5
  • 12
    • 84868467012 scopus 로고    scopus 로고
    • Regulators of skeletal development: a cluster analysis of 206 bone tumors reveals diagnostically useful markers
    • COI: 1:CAS:528:DC%2BC38Xhs1arsrnN, PID: 22766796
    • Horvai AE, Roy R, Borys D, O’Donnell RJ. Regulators of skeletal development: a cluster analysis of 206 bone tumors reveals diagnostically useful markers. Mod Pathol. 2012;25:1452–61.
    • (2012) Mod Pathol , vol.25 , pp. 1452-1461
    • Horvai, A.E.1    Roy, R.2    Borys, D.3    O’Donnell, R.J.4
  • 13
    • 0033766291 scopus 로고    scopus 로고
    • Human Dermo-1 has attributes similar to twist in early bone development
    • COI: 1:CAS:528:DC%2BD3cXosFygt7o%3D, PID: 11062344
    • Lee MS, Lowe G, Flanagan S, Kuchler K, Glackin CA. Human Dermo-1 has attributes similar to twist in early bone development. Bone. 2000;27:591–602.
    • (2000) Bone , vol.27 , pp. 591-602
    • Lee, M.S.1    Lowe, G.2    Flanagan, S.3    Kuchler, K.4    Glackin, C.A.5
  • 14
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • COI: 1:CAS:528:DC%2BD2cXlsFWnu7w%3D, PID: 15210113
    • Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell. 2004;117:927–39.
    • (2004) Cell , vol.117 , pp. 927-939
    • Yang, J.1    Mani, S.A.2    Donaher, J.L.3    Ramaswamy, S.4    Itzykson, R.A.5    Come, C.6
  • 16
    • 57449112113 scopus 로고    scopus 로고
    • Methylation of the TWIST1 promoter, TWIST1 mRNA levels, and immunohistochemical expression of TWIST1 in breast cancer
    • COI: 1:CAS:528:DC%2BD1cXhsVOgtLzI
    • Gort EH, Suijkerbuijk KP, Roothaan SM, Raman V, Vooijs M, van der Wall E, et al. Methylation of the TWIST1 promoter, TWIST1 mRNA levels, and immunohistochemical expression of TWIST1 in breast cancer. Cancer Epidemiol Biomark Prev. 2008;17:3325–30.
    • (2008) Cancer Epidemiol Biomark Prev , vol.17 , pp. 3325-3330
    • Gort, E.H.1    Suijkerbuijk, K.P.2    Roothaan, S.M.3    Raman, V.4    Vooijs, M.5    van der Wall, E.6
  • 17
    • 2442445086 scopus 로고    scopus 로고
    • Very high frequency of hypermethylated genes in breast cancer metastasis to the bone, brain, and lung
    • COI: 1:CAS:528:DC%2BD2cXjs12ltrs%3D, PID: 15131050
    • Mehrotra J, Vali M, McVeigh M, Kominsky SL, Fackler MJ, Lahti-Domenici J, et al. Very high frequency of hypermethylated genes in breast cancer metastasis to the bone, brain, and lung. Clin Cancer Res. 2004;10:3104–9.
    • (2004) Clin Cancer Res , vol.10 , pp. 3104-3109
    • Mehrotra, J.1    Vali, M.2    McVeigh, M.3    Kominsky, S.L.4    Fackler, M.J.5    Lahti-Domenici, J.6
  • 18
    • 77950680545 scopus 로고    scopus 로고
    • TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer
    • COI: 1:CAS:528:DC%2BC3cXjtFKhsLo%3D
    • Okada T, Suehiro Y, Ueno K, Mitomori S, Kaneko S, Nishioka M, et al. TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer. Gene Chromosome Cancer. 2010;49:452–62.
    • (2010) Gene Chromosome Cancer , vol.49 , pp. 452-462
    • Okada, T.1    Suehiro, Y.2    Ueno, K.3    Mitomori, S.4    Kaneko, S.5    Nishioka, M.6
  • 19
    • 34248172540 scopus 로고    scopus 로고
    • Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls
    • PID: 17324252
    • Locke I, Kote-Jarai Z, Fackler MJ, Bancroft E, Osin P, Nerurkar A, et al. Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls. Breast Cancer Res. 2007;9(1):R20.
    • (2007) Breast Cancer Res , vol.9 , Issue.1 , pp. R20
    • Locke, I.1    Kote-Jarai, Z.2    Fackler, M.J.3    Bancroft, E.4    Osin, P.5    Nerurkar, A.6
  • 20
    • 84859474055 scopus 로고    scopus 로고
    • TWIST represses estrogen receptor-alpha expression by recruiting the NuRD protein complex in breast cancer cells
    • COI: 1:CAS:528:DC%2BC38XmtVOmt7g%3D, PID: 22457607
    • Fu J, Zhang L, He T, Xiao X, Liu X, Wang L, et al. TWIST represses estrogen receptor-alpha expression by recruiting the NuRD protein complex in breast cancer cells. Int J Biol Sci. 2012;8:522–32.
    • (2012) Int J Biol Sci , vol.8 , pp. 522-532
    • Fu, J.1    Zhang, L.2    He, T.3    Xiao, X.4    Liu, X.5    Wang, L.6
  • 21
    • 79953325124 scopus 로고    scopus 로고
    • Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator Twist1
    • COI: 1:CAS:528:DC%2BC3MXmslWlsr0%3D, PID: 20219012
    • Zhao XL, Sun T, Che N, Sun D, Zhao N, Dong XY. Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator Twist1. J Cell Mol Med. 2011;15:691–700.
    • (2011) J Cell Mol Med , vol.15 , pp. 691-700
    • Zhao, X.L.1    Sun, T.2    Che, N.3    Sun, D.4    Zhao, N.5    Dong, X.Y.6
  • 22
    • 67649449918 scopus 로고    scopus 로고
    • Negative regulation of TIMP1 is mediated by transcription factor TWIST1
    • COI: 1:CAS:528:DC%2BD1MXosFSlsrY%3D, PID: 19513566
    • Okamura H, Yoshida K, Haneji T. Negative regulation of TIMP1 is mediated by transcription factor TWIST1. Int J Oncol. 2009;35:181–6.
    • (2009) Int J Oncol , vol.35 , pp. 181-186
    • Okamura, H.1    Yoshida, K.2    Haneji, T.3
  • 23
    • 79651474948 scopus 로고    scopus 로고
    • The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis
    • COI: 1:CAS:528:DC%2BC3MXhsVOmu7g%3D, PID: 20714342
    • Fu J, Qin L, He T, Qin J, Hong J, Wong J, et al. The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res. 2011;21:275–89.
    • (2011) Cell Res , vol.21 , pp. 275-289
    • Fu, J.1    Qin, L.2    He, T.3    Qin, J.4    Hong, J.5    Wong, J.6
  • 24
    • 77957583439 scopus 로고    scopus 로고
    • Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
    • PID: 20818389
    • Yang MH, Hsu DS, Wang HW, Wang HJ, Lan HY, Yang WH, et al. Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat Cell Biol. 2010;12:982–92.
    • (2010) Nat Cell Biol , vol.12 , pp. 982-992
    • Yang, M.H.1    Hsu, D.S.2    Wang, H.W.3    Wang, H.J.4    Lan, H.Y.5    Yang, W.H.6
  • 25
    • 79351468712 scopus 로고    scopus 로고
    • Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters
    • PID: 21284870
    • Li J, Zhou BP. Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC Cancer. 2011;11:49.
    • (2011) BMC Cancer , vol.11 , pp. 49
    • Li, J.1    Zhou, B.P.2
  • 26
    • 84890852964 scopus 로고    scopus 로고
    • The role of Snail in EMT and tumorigenesis
    • COI: 1:CAS:528:DC%2BC2cXit1Olsg%3D%3D, PID: 24168186
    • Wang Y, Shi J, Chai K, Ying X, Zhou BP. The role of Snail in EMT and tumorigenesis. Curr Cancer Drug Targets. 2013;13:963–72.
    • (2013) Curr Cancer Drug Targets , vol.13 , pp. 963-972
    • Wang, Y.1    Shi, J.2    Chai, K.3    Ying, X.4    Zhou, B.P.5
  • 27
    • 23844528776 scopus 로고    scopus 로고
    • The Snail genes as inducers of cell movement and survival: implications in development and cancer
    • COI: 1:CAS:528:DC%2BD2MXosVemu74%3D, PID: 15983400
    • Barrallo-Gimeno A, Nieto MA. The Snail genes as inducers of cell movement and survival: implications in development and cancer. Development. 2005;132:3151–61.
    • (2005) Development , vol.132 , pp. 3151-3161
    • Barrallo-Gimeno, A.1    Nieto, M.A.2
  • 28
    • 0346363757 scopus 로고    scopus 로고
    • Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
    • COI: 1:CAS:528:DC%2BD2cXhtVWmtQ%3D%3D, PID: 14673164
    • Peinado H, Ballestar E, Esteller M, Cano A. Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol. 2004;24:306–19.
    • (2004) Mol Cell Biol , vol.24 , pp. 306-319
    • Peinado, H.1    Ballestar, E.2    Esteller, M.3    Cano, A.4
  • 29
    • 70349859809 scopus 로고    scopus 로고
    • Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
    • COI: 1:CAS:528:DC%2BD1MXhtlGnsbzO, PID: 19544473
    • Kurrey NK, Jalgaonkar SP, Joglekar AV, Ghanate AD, Chaskar PD, Doiphode RY, et al. Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells. 2009;27(9):2059–68.
    • (2009) Stem Cells , vol.27 , Issue.9 , pp. 2059-2068
    • Kurrey, N.K.1    Jalgaonkar, S.P.2    Joglekar, A.V.3    Ghanate, A.D.4    Chaskar, P.D.5    Doiphode, R.Y.6
  • 30
    • 84864360562 scopus 로고    scopus 로고
    • Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
    • COI: 1:CAS:528:DC%2BC38XhtVansbbP, PID: 22349261
    • Gheldof A, Hulpiau P, van Roy F, De Craene B, Berx G. Evolutionary functional analysis and molecular regulation of the ZEB transcription factors. Cell Mol Life Sci. 2012;69:2527–41.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 2527-2541
    • Gheldof, A.1    Hulpiau, P.2    van Roy, F.3    De Craene, B.4    Berx, G.5
  • 31
    • 77950502330 scopus 로고    scopus 로고
    • ZEB proteins link cell motility with cell cycle control and cell survival in cancer
    • COI: 1:CAS:528:DC%2BC3cXht12ktb%2FL, PID: 20160487
    • Browne G, Sayan AE, Tulchinsky E. ZEB proteins link cell motility with cell cycle control and cell survival in cancer. Cell Cycle. 2010;9:886–91.
    • (2010) Cell Cycle , vol.9 , pp. 886-891
    • Browne, G.1    Sayan, A.E.2    Tulchinsky, E.3
  • 33
    • 79957897561 scopus 로고    scopus 로고
    • SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation
    • COI: 1:CAS:528:DC%2BC3MXnsFamtrg%3D, PID: 21645397
    • Acun T, Oztas E, Yagci T, Yakicier MC. SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. BMC Cancer. 2011;11:223.
    • (2011) BMC Cancer , vol.11 , pp. 223
    • Acun, T.1    Oztas, E.2    Yagci, T.3    Yakicier, M.C.4
  • 34
    • 65849265065 scopus 로고    scopus 로고
    • Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays
    • PID: 18638373
    • Rodenhiser DI, Andrews J, Kennette W, Sadikovic B, Mendlowitz A, Tuck AB, et al. Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays. Breast Cancer Res. 2008;10:R62.
    • (2008) Breast Cancer Res , vol.10 , pp. R62
    • Rodenhiser, D.I.1    Andrews, J.2    Kennette, W.3    Sadikovic, B.4    Mendlowitz, A.5    Tuck, A.B.6
  • 35
    • 77954354936 scopus 로고    scopus 로고
    • Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels
    • COI: 1:CAS:528:DC%2BC3cXot1Wlu74%3D, PID: 20551052
    • Li A, Omura N, Hong SM, Vincent A, Walter K, Griffith M, et al. Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels. Cancer Res. 2010;70:5226–37.
    • (2010) Cancer Res , vol.70 , pp. 5226-5237
    • Li, A.1    Omura, N.2    Hong, S.M.3    Vincent, A.4    Walter, K.5    Griffith, M.6
  • 36
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    • COI: 1:CAS:528:DC%2BD1MXhsV2gsLnM, PID: 19935649
    • Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A, et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol. 2009;11:1487–95.
    • (2009) Nat Cell Biol , vol.11 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3    Schmalhofer, O.4    Zhu, F.5    Sonntag, A.6
  • 37
    • 33846550531 scopus 로고    scopus 로고
    • Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients
    • COI: 1:CAS:528:DC%2BD2sXotFelsw%3D%3D, PID: 17211477
    • Hosono S, Kajiyama H, Terauchi M, Shibata K, Ino K, Nawa A, et al. Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients. Br J Cancer. 2007;96:314–20.
    • (2007) Br J Cancer , vol.96 , pp. 314-320
    • Hosono, S.1    Kajiyama, H.2    Terauchi, M.3    Shibata, K.4    Ino, K.5    Nawa, A.6
  • 38
    • 35348870930 scopus 로고    scopus 로고
    • Upregulation of Twist induces angiogenesis and correlates with metastasis in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BD2sXhtlSlur7K, PID: 17987801
    • Niu RF, Zhang L, Xi GM, Wei XY, Yang Y, Shi YR, et al. Upregulation of Twist induces angiogenesis and correlates with metastasis in hepatocellular carcinoma. J Exp Clin Cancer Res. 2007;26:385–94.
    • (2007) J Exp Clin Cancer Res , vol.26 , pp. 385-394
    • Niu, R.F.1    Zhang, L.2    Xi, G.M.3    Wei, X.Y.4    Yang, Y.5    Shi, Y.R.6
  • 39
    • 47849086547 scopus 로고    scopus 로고
    • Effect and mechanism of the Twist gene on invasion and metastasis of gastric carcinoma cells
    • COI: 1:CAS:528:DC%2BD1cXptlWgs7k%3D, PID: 18442194
    • Luo GQ, Li JH, Wen JF, Zhou YH, Hu YB, Zhou JH. Effect and mechanism of the Twist gene on invasion and metastasis of gastric carcinoma cells. World J Gastroenterol. 2008;14:2487–93.
    • (2008) World J Gastroenterol , vol.14 , pp. 2487-2493
    • Luo, G.Q.1    Li, J.H.2    Wen, J.F.3    Zhou, Y.H.4    Hu, Y.B.5    Zhou, J.H.6
  • 40
    • 34249866557 scopus 로고    scopus 로고
    • Upregulation of Twist in oesophageal squamous cell carcinoma is associated with neoplastic transformation and distant metastasis
    • COI: 1:CAS:528:DC%2BD2sXnt1Gkurk%3D, PID: 16822877
    • Yuen HF, Chan YP, Wong ML, Kwok WK, Chan KK, Lee PY, et al. Upregulation of Twist in oesophageal squamous cell carcinoma is associated with neoplastic transformation and distant metastasis. J Clin Pathol. 2007;60:510–4.
    • (2007) J Clin Pathol , vol.60 , pp. 510-514
    • Yuen, H.F.1    Chan, Y.P.2    Wong, M.L.3    Kwok, W.K.4    Chan, K.K.5    Lee, P.Y.6
  • 41
    • 33749236403 scopus 로고    scopus 로고
    • The clinical significance of twist expression in nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BD28XhtVGit7jJ, PID: 16412561
    • Song LB, Liao WT, Mai HQ, Zhang HZ, Zhang L, Li MZ, et al. The clinical significance of twist expression in nasopharyngeal carcinoma. Cancer Lett. 2006;242:258–65.
    • (2006) Cancer Lett , vol.242 , pp. 258-265
    • Song, L.B.1    Liao, W.T.2    Mai, H.Q.3    Zhang, H.Z.4    Zhang, L.5    Li, M.Z.6
  • 42
    • 33947639964 scopus 로고    scopus 로고
    • Significance of TWIST and E-cadherin expression in the metastatic progression of prostatic cancer
    • PID: 17394502
    • Yuen HF, Chua CW, Chan YP, Wong YC, Wang X, Chan KW. Significance of TWIST and E-cadherin expression in the metastatic progression of prostatic cancer. Histopathology. 2007;50:648–58.
    • (2007) Histopathology , vol.50 , pp. 648-658
    • Yuen, H.F.1    Chua, C.W.2    Chan, Y.P.3    Wong, Y.C.4    Wang, X.5    Chan, K.W.6
  • 43
    • 76649134077 scopus 로고    scopus 로고
    • Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer
    • COI: 1:CAS:528:DC%2BC3cXkt1ektw%3D%3D, PID: 20012924
    • McConkey DJ, Choi W, Marquis L, Martin F, Williams MB, Shah J, et al. Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer. Cancer Metastasis Rev. 2009;28:335–44.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 335-344
    • McConkey, D.J.1    Choi, W.2    Marquis, L.3    Martin, F.4    Williams, M.B.5    Shah, J.6
  • 44
    • 33644873765 scopus 로고    scopus 로고
    • TWIST is expressed in human gliomas and promotes invasion
    • COI: 1:CAS:528:DC%2BD2MXhtlClurbJ, PID: 16229805
    • Elias MC, Tozer KR, Silber JR, Mikheeva S, Deng M, Morrison RS, et al. TWIST is expressed in human gliomas and promotes invasion. Neoplasia. 2005;7:824–37.
    • (2005) Neoplasia , vol.7 , pp. 824-837
    • Elias, M.C.1    Tozer, K.R.2    Silber, J.R.3    Mikheeva, S.4    Deng, M.5    Morrison, R.S.6
  • 45
    • 42549134455 scopus 로고    scopus 로고
    • Role of Twist in head and neck carcinoma with lymph node metastasis
    • COI: 1:CAS:528:DC%2BD1cXmt1egsro%3D, PID: 18505078
    • Ou DL, Chien HF, Chen CL, Lin TC, Lin LI. Role of Twist in head and neck carcinoma with lymph node metastasis. Anticancer Res. 2008;28:1355–9.
    • (2008) Anticancer Res , vol.28 , pp. 1355-1359
    • Ou, D.L.1    Chien, H.F.2    Chen, C.L.3    Lin, T.C.4    Lin, L.I.5
  • 47
    • 84860394083 scopus 로고    scopus 로고
    • The role of TWIST as a regulator in giant cell tumor of bone
    • COI: 1:CAS:528:DC%2BC3MXhtVegtbnJ, PID: 21503964
    • Singh S, Mak IW, Cowan RW, Turcotte R, Singh G, Ghert M. The role of TWIST as a regulator in giant cell tumor of bone. J Cell Biochem. 2011;112:2287–95.
    • (2011) J Cell Biochem , vol.112 , pp. 2287-2295
    • Singh, S.1    Mak, I.W.2    Cowan, R.W.3    Turcotte, R.4    Singh, G.5    Ghert, M.6
  • 48
    • 78649317775 scopus 로고    scopus 로고
    • DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast
    • COI: 1:CAS:528:DC%2BC3cXht12qur%2FK, PID: 20563638
    • Huang KT, Dobrovic A, Yan M, Karim RZ, Lee CS, Lakhani SR, et al. DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast. Breast Cancer Res Treat. 2010;124:555–65.
    • (2010) Breast Cancer Res Treat , vol.124 , pp. 555-565
    • Huang, K.T.1    Dobrovic, A.2    Yan, M.3    Karim, R.Z.4    Lee, C.S.5    Lakhani, S.R.6
  • 49
    • 78650247441 scopus 로고    scopus 로고
    • Promoter hypermethylation of CDH13, DAPK1 and TWIST1 genes in precancerous and cancerous lesions of the uterine cervix
    • COI: 1:CAS:528:DC%2BC3cXhsFygur3O, PID: 21129853
    • Missaoui N, Hmissa S, Trabelsi A, Traoré C, Mokni M, Dante R, et al. Promoter hypermethylation of CDH13, DAPK1 and TWIST1 genes in precancerous and cancerous lesions of the uterine cervix. Pathol Res Pract. 2011;207:37–42.
    • (2011) Pathol Res Pract , vol.207 , pp. 37-42
    • Missaoui, N.1    Hmissa, S.2    Trabelsi, A.3    Traoré, C.4    Mokni, M.5    Dante, R.6
  • 50
    • 4143070300 scopus 로고    scopus 로고
    • The contribution of genetic and epigenetic changes in granulosa cell tumors of ovarian origin
    • COI: 1:CAS:528:DC%2BD2cXmvFSltbk%3D, PID: 15328194
    • Dhillon VS, Aslam M, Husain SA. The contribution of genetic and epigenetic changes in granulosa cell tumors of ovarian origin. Clin Cancer Res. 2004;10:5537–45.
    • (2004) Clin Cancer Res , vol.10 , pp. 5537-5545
    • Dhillon, V.S.1    Aslam, M.2    Husain, S.A.3
  • 51
    • 77952883763 scopus 로고    scopus 로고
    • Identification and validation of the methylated TWIST1 and NID2 genes through real-time methylation-specific polymerase chain reaction assays for the noninvasive detection of primary bladder cancer in urine samples
    • COI: 1:CAS:528:DC%2BC3cXps1entrc%3D, PID: 19674832
    • Renard I, Joniau S, van Cleynenbreugel B, Collette C, Naômé C, Vlassenbroeck I, et al. Identification and validation of the methylated TWIST1 and NID2 genes through real-time methylation-specific polymerase chain reaction assays for the noninvasive detection of primary bladder cancer in urine samples. Eur Urol. 2010;58:96–104.
    • (2010) Eur Urol , vol.58 , pp. 96-104
    • Renard, I.1    Joniau, S.2    van Cleynenbreugel, B.3    Collette, C.4    Naômé, C.5    Vlassenbroeck, I.6
  • 52
    • 78049518932 scopus 로고    scopus 로고
    • Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer
    • COI: 1:CAS:528:DC%2BC3cXhsVGht77M, PID: 20178103
    • Schneider BG, Peng DF, Camargo MC, Piazuelo MB, Sicinschi LA, Mera R, et al. Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer. Int J Cancer. 2010;127:2588–97.
    • (2010) Int J Cancer , vol.127 , pp. 2588-2597
    • Schneider, B.G.1    Peng, D.F.2    Camargo, M.C.3    Piazuelo, M.B.4    Sicinschi, L.A.5    Mera, R.6
  • 53
    • 38349173162 scopus 로고    scopus 로고
    • Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma
    • PID: 17967182
    • Tsou JA, Galler JS, Siegmund KD, Laird PW, Turla S, Cozen W, et al. Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma. Mol Cancer. 2007;6:70.
    • (2007) Mol Cancer , vol.6 , pp. 70
    • Tsou, J.A.1    Galler, J.S.2    Siegmund, K.D.3    Laird, P.W.4    Turla, S.5    Cozen, W.6
  • 54
    • 84883458394 scopus 로고    scopus 로고
    • TWIST1 promoter methylation is associated with prognosis in tonsillar squamous cell carcinoma
    • COI: 1:CAS:528:DC%2BC3sXns1Kit7Y%3D, PID: 23664538
    • Kwon MJ, Kwon JH, Nam ES, Shin HS, Lee DJ, Kim JH, et al. TWIST1 promoter methylation is associated with prognosis in tonsillar squamous cell carcinoma. Hum Pathol. 2013;44:1722–9.
    • (2013) Hum Pathol , vol.44 , pp. 1722-1729
    • Kwon, M.J.1    Kwon, J.H.2    Nam, E.S.3    Shin, H.S.4    Lee, D.J.5    Kim, J.H.6
  • 55
    • 24944450362 scopus 로고    scopus 로고
    • The transcriptional repressor Snail promotes mammary tumor recurrence
    • COI: 1:CAS:528:DC%2BD2MXhtV2gt7rF, PID: 16169465
    • Moody SE, Perez D, Pan TC, Sarkisian CJ, Portocarrero CP, Sterner CJ, et al. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell. 2005;8:197–209.
    • (2005) Cancer Cell , vol.8 , pp. 197-209
    • Moody, S.E.1    Perez, D.2    Pan, T.C.3    Sarkisian, C.J.4    Portocarrero, C.P.5    Sterner, C.J.6
  • 56
    • 84878583653 scopus 로고    scopus 로고
    • Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells
    • COI: 1:CAS:528:DC%2BC38XhsVKisbnF, PID: 23342249
    • Fan F, Samuel S, Evans KW, Lu J, Xia L, Zhou Y, et al. Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells. Cancer Med. 2012;1:5–16.
    • (2012) Cancer Med , vol.1 , pp. 5-16
    • Fan, F.1    Samuel, S.2    Evans, K.W.3    Lu, J.4    Xia, L.5    Zhou, Y.6
  • 57
    • 84860264531 scopus 로고    scopus 로고
    • Snail overexpression induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells
    • COI: 1:CAS:528:DC%2BC38XmtlGgt7o%3D, PID: 22349639
    • Zhu LF, Hu Y, Yang CC, Xu XH, Ning TY, Wang ZL, et al. Snail overexpression induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells. Lab Invest. 2012;92:744–52.
    • (2012) Lab Invest , vol.92 , pp. 744-752
    • Zhu, L.F.1    Hu, Y.2    Yang, C.C.3    Xu, X.H.4    Ning, T.Y.5    Wang, Z.L.6
  • 58
    • 84868689227 scopus 로고    scopus 로고
    • Overexpression of Snail is associated with lymph node metastasis and poor prognosis in patients with gastric cancer
    • COI: 1:CAS:528:DC%2BC3sXjtVKitro%3D, PID: 23151184
    • Shin NR, Jeong EH, Choi CI, Moon HJ, Kwon CH, Chu IS, et al. Overexpression of Snail is associated with lymph node metastasis and poor prognosis in patients with gastric cancer. BMC Cancer. 2012;12:521.
    • (2012) BMC Cancer , vol.12 , pp. 521
    • Shin, N.R.1    Jeong, E.H.2    Choi, C.I.3    Moon, H.J.4    Kwon, C.H.5    Chu, I.S.6
  • 59
    • 84899576175 scopus 로고    scopus 로고
    • Expression profiles of epithelial-mesenchymal transition-associated proteins in epithelial ovarian carcinoma
    • PID: 24800235
    • Kim MK, Kim MA, Kim H, Kim YB, Song YS. Expression profiles of epithelial-mesenchymal transition-associated proteins in epithelial ovarian carcinoma. Biomed Res Int. 2014;2014:495754.
    • (2014) Biomed Res Int , vol.2014 , pp. 495754
    • Kim, M.K.1    Kim, M.A.2    Kim, H.3    Kim, Y.B.4    Song, Y.S.5
  • 60
    • 14544297919 scopus 로고    scopus 로고
    • The transcriptional repressor SNAIL is overexpressed in human colon cancer
    • COI: 1:CAS:528:DC%2BD2MXhs1equ74%3D, PID: 15712635
    • Roy HK, Smyrk TC, Koetsier J, Victor TA, Wali RK. The transcriptional repressor SNAIL is overexpressed in human colon cancer. Dig Dis Sci. 2005;50:42–6.
    • (2005) Dig Dis Sci , vol.50 , pp. 42-46
    • Roy, H.K.1    Smyrk, T.C.2    Koetsier, J.3    Victor, T.A.4    Wali, R.K.5
  • 61
    • 84892440278 scopus 로고    scopus 로고
    • Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential
    • PID: 24162662
    • De Craene B, Denecker G, Vermassen P, Taminau J, Mauch C, Derore A, et al. Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential. Cell Death Differ. 2014;21:310–20.
    • (2014) Cell Death Differ , vol.21 , pp. 310-320
    • De Craene, B.1    Denecker, G.2    Vermassen, P.3    Taminau, J.4    Mauch, C.5    Derore, A.6
  • 62
    • 84888417066 scopus 로고    scopus 로고
    • Roles of transcriptional factor Snail and adhesion factor E-cadherin in clear cell renal cell carcinoma
    • PID: 24255679
    • Cai J. Roles of transcriptional factor Snail and adhesion factor E-cadherin in clear cell renal cell carcinoma. Exp Ther Med. 2013;6:1489–93.
    • (2013) Exp Ther Med , vol.6 , pp. 1489-1493
    • Cai, J.1
  • 63
    • 84864452523 scopus 로고    scopus 로고
    • Snail transcription factor negatively regulates maspin tumor suppressor in human prostate cancer cells
    • COI: 1:CAS:528:DC%2BC38Xhs1SisbjP, PID: 22857708
    • Neal CL, Henderson V, Smith BN, McKeithen D, Graham T, Vo BT, et al. Snail transcription factor negatively regulates maspin tumor suppressor in human prostate cancer cells. BMC Cancer. 2012;12:336.
    • (2012) BMC Cancer , vol.12 , pp. 336
    • Neal, C.L.1    Henderson, V.2    Smith, B.N.3    McKeithen, D.4    Graham, T.5    Vo, B.T.6
  • 64
    • 33947664420 scopus 로고    scopus 로고
    • Slug is overexpressed in gastric carcinomas and may act synergistically with SIP1 and Snail in the down-regulation of E-cadherin
    • COI: 1:STN:280:DC%2BD2s7ntVyksw%3D%3D, PID: 17299729
    • Castro Alves C, Rosivatz E, Schott C, Hollweck R, Becker I, Sarbia M, et al. Slug is overexpressed in gastric carcinomas and may act synergistically with SIP1 and Snail in the down-regulation of E-cadherin. J Pathol. 2007;211:507–15.
    • (2007) J Pathol , vol.211 , pp. 507-515
    • Castro Alves, C.1    Rosivatz, E.2    Schott, C.3    Hollweck, R.4    Becker, I.5    Sarbia, M.6
  • 65
    • 80052403945 scopus 로고    scopus 로고
    • The EMT regulator slug and lung carcinogenesis
    • COI: 1:CAS:528:DC%2BC3MXhtFehtbrK, PID: 21665887
    • Shih JY, Yang PC. The EMT regulator slug and lung carcinogenesis. Carcinogenesis. 2011;32:1299–304.
    • (2011) Carcinogenesis , vol.32 , pp. 1299-1304
    • Shih, J.Y.1    Yang, P.C.2
  • 66
    • 33745086313 scopus 로고    scopus 로고
    • Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients
    • COI: 1:CAS:528:DC%2BD28XlsFequ7s%3D, PID: 16773075
    • Shioiri M, Shida T, Koda K, Oda K, Seike K, Nishimura M, et al. Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients. Br J Cancer. 2006;94:1816–22.
    • (2006) Br J Cancer , vol.94 , pp. 1816-1822
    • Shioiri, M.1    Shida, T.2    Koda, K.3    Oda, K.4    Seike, K.5    Nishimura, M.6
  • 68
    • 79952075985 scopus 로고    scopus 로고
    • Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling
    • COI: 1:CAS:528:DC%2BC3MXisVKrurw%3D, PID: 21283078
    • Zhang K, Chen D, Jiao X, Zhang S, Liu X, Cao J, et al. Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling. Lab Invest. 2011;91:426–38.
    • (2011) Lab Invest , vol.91 , pp. 426-438
    • Zhang, K.1    Chen, D.2    Jiao, X.3    Zhang, S.4    Liu, X.5    Cao, J.6
  • 69
    • 16844368863 scopus 로고    scopus 로고
    • Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
    • COI: 1:CAS:528:DC%2BD2MXjvVymtbw%3D, PID: 15742334
    • Elloul S, Elstrand MB, Nesland JM, Tropé CG, Kvalheim G, Goldberg I, et al. Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer. 2005;103:1631–43.
    • (2005) Cancer , vol.103 , pp. 1631-1643
    • Elloul, S.1    Elstrand, M.B.2    Nesland, J.M.3    Tropé, C.G.4    Kvalheim, G.5    Goldberg, I.6
  • 70
    • 80755143039 scopus 로고    scopus 로고
    • SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis
    • COI: 1:CAS:528:DC%2BC38XksFGrug%3D%3D, PID: 22074556
    • Uygur B, Wu WS. SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis. Mol Cancer. 2011;10:139.
    • (2011) Mol Cancer , vol.10 , pp. 139
    • Uygur, B.1    Wu, W.S.2
  • 71
    • 27744527762 scopus 로고    scopus 로고
    • Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BD2MXht12hu7fI, PID: 16285938
    • Giannelli G, Bergamini C, Fransvea E, Sgarra C, Antonaci S. Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma. Gastroenterology. 2005;129:1375–83.
    • (2005) Gastroenterology , vol.129 , pp. 1375-1383
    • Giannelli, G.1    Bergamini, C.2    Fransvea, E.3    Sgarra, C.4    Antonaci, S.5
  • 72
    • 33645732687 scopus 로고    scopus 로고
    • The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers
    • COI: 1:CAS:528:DC%2BD28XjtVOqsrk%3D, PID: 16585218
    • Spoelstra NS, Manning NG, Higashi Y, Darling D, Singh M, Shroyer KR, et al. The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers. Cancer Res. 2006;66:3893–902.
    • (2006) Cancer Res , vol.66 , pp. 3893-3902
    • Spoelstra, N.S.1    Manning, N.G.2    Higashi, Y.3    Darling, D.4    Singh, M.5    Shroyer, K.R.6
  • 73
    • 33748116186 scopus 로고    scopus 로고
    • A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
    • COI: 1:CAS:528:DC%2BD28XhtVKrurnP, PID: 16952552
    • Spaderna S, Schmalhofer O, Hlubek F, Berx G, Eger A, Merkel S, et al. A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology. 2006;131:830–40.
    • (2006) Gastroenterology , vol.131 , pp. 830-840
    • Spaderna, S.1    Schmalhofer, O.2    Hlubek, F.3    Berx, G.4    Eger, A.5    Merkel, S.6
  • 74
    • 33744925683 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
    • COI: 1:CAS:528:DC%2BD28XksF2isbw%3D, PID: 16707460
    • Dohadwala M, Yang SC, Luo J, Sharma S, Batra RK, Huang M, et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res. 2006;66:5338–45.
    • (2006) Cancer Res , vol.66 , pp. 5338-5345
    • Dohadwala, M.1    Yang, S.C.2    Luo, J.3    Sharma, S.4    Batra, R.K.5    Huang, M.6
  • 75
    • 42049092980 scopus 로고    scopus 로고
    • Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells
    • COI: 1:CAS:528:DC%2BD1cXktV2js7c%3D, PID: 18381457
    • Graham TR, Zhau HE, Odero-Marah VA, Osunkoya AO, Kimbro KS, Tighiouart M, et al. Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells. Cancer Res. 2008;68:2479–88.
    • (2008) Cancer Res , vol.68 , pp. 2479-2488
    • Graham, T.R.1    Zhau, H.E.2    Odero-Marah, V.A.3    Osunkoya, A.O.4    Kimbro, K.S.5    Tighiouart, M.6
  • 76
    • 58149529709 scopus 로고    scopus 로고
    • Zeb1-mediated T-cadherin repression increases the invasive potential of gallbladder cancer
    • COI: 1:CAS:528:DC%2BD1MXotlKlug%3D%3D, PID: 19116147
    • Adachi Y, Takeuchi T, Nagayama T, Ohtsuki Y, Furihata M. Zeb1-mediated T-cadherin repression increases the invasive potential of gallbladder cancer. FEBS Lett. 2009;583:430–6.
    • (2009) FEBS Lett , vol.583 , pp. 430-436
    • Adachi, Y.1    Takeuchi, T.2    Nagayama, T.3    Ohtsuki, Y.4    Furihata, M.5
  • 77
    • 70349273757 scopus 로고    scopus 로고
    • SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer
    • COI: 1:CAS:528:DC%2BD1MXhtFGrt7%2FK, PID: 19706487
    • Sayan AE, Griffiths TR, Pal R, Browne GJ, Ruddick A, Yagci T, et al. SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer. Proc Natl Acad Sci U S A. 2009;106:14884–9.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14884-14889
    • Sayan, A.E.1    Griffiths, T.R.2    Pal, R.3    Browne, G.J.4    Ruddick, A.5    Yagci, T.6
  • 78
    • 84860578009 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
    • PID: 22505459
    • Celià-Terrassa T, Meca-Cortés O, Mateo F, de Paz AM, Rubio N, Arnal-Estapé A, et al. Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells. J Clin Invest. 2012;122:1849–68.
    • (2012) J Clin Invest , vol.122 , pp. 1849-1868
    • Celià-Terrassa, T.1    Meca-Cortés, O.2    Mateo, F.3    de Paz, A.M.4    Rubio, N.5    Arnal-Estapé, A.6
  • 79
    • 84872416422 scopus 로고    scopus 로고
    • Biomarkers of epithelial-mesenchymal transition in squamous cell carcinoma
    • COI: 1:STN:280:DC%2BC3s7htVGqtw%3D%3D, PID: 23128109
    • Scanlon CS, Van Tubergen EA, Inglehart RC, D’Silva NJ. Biomarkers of epithelial-mesenchymal transition in squamous cell carcinoma. J Dent Res. 2013;92:114–21.
    • (2013) J Dent Res , vol.92 , pp. 114-121
    • Scanlon, C.S.1    Van Tubergen, E.A.2    Inglehart, R.C.3    D’Silva, N.J.4
  • 80
    • 41149143022 scopus 로고    scopus 로고
    • Short interfering RNA directed against TWIST, a novel zinc finger transcription factor, increases A549 cell sensitivity to cisplatin via MAPK/mitochondrial pathway
    • COI: 1:CAS:528:DC%2BD1cXksVejtbs%3D, PID: 18331824
    • Zhuo WL, Wang Y, Zhuo XL, Zhang YS, Chen ZT. Short interfering RNA directed against TWIST, a novel zinc finger transcription factor, increases A549 cell sensitivity to cisplatin via MAPK/mitochondrial pathway. Biochem Biophys Res Commun. 2008;369:1098–102.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 1098-1102
    • Zhuo, W.L.1    Wang, Y.2    Zhuo, X.L.3    Zhang, Y.S.4    Chen, Z.T.5
  • 81
    • 65249155400 scopus 로고    scopus 로고
    • Twist1-mediated adriamycin-induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells
    • COI: 1:CAS:528:DC%2BD1MXksV2nsLY%3D, PID: 19336515
    • Li QQ, Xu JD, Wang WJ, Cao XX, Chen Q, Tang F, et al. Twist1-mediated adriamycin-induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells. Clin Cancer Res. 2009;15:2657–65.
    • (2009) Clin Cancer Res , vol.15 , pp. 2657-2665
    • Li, Q.Q.1    Xu, J.D.2    Wang, W.J.3    Cao, X.X.4    Chen, Q.5    Tang, F.6
  • 82
    • 78650413780 scopus 로고    scopus 로고
    • Dietary curcumin attenuates glioma growth in a syngeneic mouse model by inhibition of the JAK1,2/STAT3 signaling pathway
    • COI: 1:CAS:528:DC%2BC3cXhsFamtLrF, PID: 21138870
    • Weissenberger J, Priester M, Bernreuther C, Rakel S, Glatzel M, Seifert V, et al. Dietary curcumin attenuates glioma growth in a syngeneic mouse model by inhibition of the JAK1,2/STAT3 signaling pathway. Clin Cancer Res. 2010;16:5781–95.
    • (2010) Clin Cancer Res , vol.16 , pp. 5781-5795
    • Weissenberger, J.1    Priester, M.2    Bernreuther, C.3    Rakel, S.4    Glatzel, M.5    Seifert, V.6
  • 83
    • 79957794952 scopus 로고    scopus 로고
    • Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells
    • Srivastava RK, Tang SN, Zhu W, Meeker D, Shankar S. Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells. Front Biosci (Elite Ed). 2011;3:515–28.
    • (2011) Front Biosci (Elite Ed) , vol.3 , pp. 515-528
    • Srivastava, R.K.1    Tang, S.N.2    Zhu, W.3    Meeker, D.4    Shankar, S.5
  • 84
    • 84874108284 scopus 로고    scopus 로고
    • Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer
    • PID: 22422628
    • Chang WW, Hu FW, Yu CC, Wang HH, Feng HP, Lan C, et al. Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer. Head Neck. 2013;35:413–9.
    • (2013) Head Neck , vol.35 , pp. 413-419
    • Chang, W.W.1    Hu, F.W.2    Yu, C.C.3    Wang, H.H.4    Feng, H.P.5    Lan, C.6
  • 85
    • 84875719759 scopus 로고    scopus 로고
    • Moscatilin inhibits migration and metastasis of human breast cancer MDA-MB-231 cells through inhibition of Akt and Twist signaling pathway
    • COI: 1:CAS:528:DC%2BC3sXjtlygu7s%3D
    • Pai HC, Chang LH, Peng CY, Chang YL, Chen CC, Shen CC, et al. Moscatilin inhibits migration and metastasis of human breast cancer MDA-MB-231 cells through inhibition of Akt and Twist signaling pathway. J Mol Med (Berl). 2013;91:347–56.
    • (2013) J Mol Med (Berl) , vol.91 , pp. 347-356
    • Pai, H.C.1    Chang, L.H.2    Peng, C.Y.3    Chang, Y.L.4    Chen, C.C.5    Shen, C.C.6
  • 86
    • 84939928042 scopus 로고    scopus 로고
    • Khan MA, Yang M, Wei C, Gan L, Fu J. Thymoquinone downregulates n-cadherin, twist and snail expression and inhibits migration and invasion in cancer cells. Proceedings of Annual meeting of American Association of Cancer Research; April 05-09, 2014 at San Diego, USA (Abstract No. 5009)
    • Khan MA, Yang M, Wei C, Gan L, Fu J. Thymoquinone downregulates n-cadherin, twist and snail expression and inhibits migration and invasion in cancer cells. Proceedings of Annual meeting of American Association of Cancer Research; April 05-09, 2014 at San Diego, USA (Abstract No. 5009).
  • 87
    • 84899934299 scopus 로고    scopus 로고
    • ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition
    • PID: 24766737
    • Lin X, Yi Z, Diao J, Shao M, Zhao L, Cai H, et al. ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. J Transl Med. 2014;12:105.
    • (2014) J Transl Med , vol.12 , pp. 105
    • Lin, X.1    Yi, Z.2    Diao, J.3    Shao, M.4    Zhao, L.5    Cai, H.6
  • 88
    • 84904958092 scopus 로고    scopus 로고
    • Huang Y, Liu W, Liu H, Yang Y, Cui J, Zhang P, et al. Grape seed pro-anthocyanidins ameliorates radiation-induced lung injury. J Cell Mol Med. 2014 Apr 24. (in press)
    • Huang Y, Liu W, Liu H, Yang Y, Cui J, Zhang P, et al. Grape seed pro-anthocyanidins ameliorates radiation-induced lung injury. J Cell Mol Med. 2014 Apr 24. (in press).
  • 89
    • 84901399890 scopus 로고    scopus 로고
    • Lv M, Li Y, Ji MH, Zhuang M, Tang JH. Inhibition of invasion and epithelial-mesenchymal transition of human breast cancer cells by hydrogen sulfide through decreased phospho-p38 expression. Mol Med Rep. 2014 Apr 17. (in press)
    • Lv M, Li Y, Ji MH, Zhuang M, Tang JH. Inhibition of invasion and epithelial-mesenchymal transition of human breast cancer cells by hydrogen sulfide through decreased phospho-p38 expression. Mol Med Rep. 2014 Apr 17. (in press).
  • 90
    • 84901465771 scopus 로고    scopus 로고
    • Bao B, Azmi A, Aboukameel A, Ahmad A, Bolling-Fischer A, Sethi S, et al. Pancreatic cancer stem-like cells display aggressive behavior mediated via activation of FoxQ1. J Biol Chem. 2014 Apr 9. (in press)
    • Bao B, Azmi A, Aboukameel A, Ahmad A, Bolling-Fischer A, Sethi S, et al. Pancreatic cancer stem-like cells display aggressive behavior mediated via activation of FoxQ1. J Biol Chem. 2014 Apr 9. (in press).
  • 91
    • 84939928046 scopus 로고    scopus 로고
    • Zhang JP, Zeng C, Xu L, Gong J, Fang JH, Zhuang SM. MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling. Oncogene
    • Zhang JP, Zeng C, Xu L, Gong J, Fang JH, Zhuang SM. MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling. Oncogene. 2013 Sep 9. (in press).
  • 92
    • 84884523034 scopus 로고    scopus 로고
    • Snail family proteins in cervical squamous carcinoma: expression and significance
    • COI: 1:CAS:528:DC%2BC3sXhsV2lurzI, PID: 23906494
    • Zhao W, Zhou Y, Xu H, Cheng Y, Kong B. Snail family proteins in cervical squamous carcinoma: expression and significance. Clin Invest Med. 2013;36:E223–33.
    • (2013) Clin Invest Med , vol.36 , pp. E223-E233
    • Zhao, W.1    Zhou, Y.2    Xu, H.3    Cheng, Y.4    Kong, B.5
  • 93
    • 84891389727 scopus 로고    scopus 로고
    • Stability and prognostic value of Slug, Sox9 and Sox10 expression in breast cancers treated with neoadjuvant chemotherapy
    • PID: 24404438
    • Riemenschnitter C, Teleki I, Tischler V, Guo W, Varga Z. Stability and prognostic value of Slug, Sox9 and Sox10 expression in breast cancers treated with neoadjuvant chemotherapy. Springerplus. 2013;2:695.
    • (2013) Springerplus , vol.2 , pp. 695
    • Riemenschnitter, C.1    Teleki, I.2    Tischler, V.3    Guo, W.4    Varga, Z.5
  • 94
    • 84898663718 scopus 로고    scopus 로고
    • Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma
    • PID: 24233839
    • Lee HJ, Jeng YM, Chen YL, Chung L, Yuan RH. Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma. Carcinogenesis. 2013;35:769–75.
    • (2013) Carcinogenesis , vol.35 , pp. 769-775
    • Lee, H.J.1    Jeng, Y.M.2    Chen, Y.L.3    Chung, L.4    Yuan, R.H.5
  • 95
    • 84885398079 scopus 로고    scopus 로고
    • Combination of rapamycin, CI-1040, and 17-AAG inhibits metastatic capacity of prostate cancer via Slug inhibition
    • COI: 1:CAS:528:DC%2BC3sXhs1Cjsr%2FN, PID: 24130883
    • Ding G, Feng C, Jiang H, Ding Q, Zhang L, Na R, et al. Combination of rapamycin, CI-1040, and 17-AAG inhibits metastatic capacity of prostate cancer via Slug inhibition. PLoS One. 2013;8:e77400.
    • (2013) PLoS One , vol.8 , pp. e77400
    • Ding, G.1    Feng, C.2    Jiang, H.3    Ding, Q.4    Zhang, L.5    Na, R.6
  • 96
    • 84882344200 scopus 로고    scopus 로고
    • From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review)
    • COI: 1:CAS:528:DC%2BC3sXhs1CmsbrP, PID: 23939688
    • Piva R, Spandidos DA, Gambari R. From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review). Int J Oncol. 2013;43:985–94.
    • (2013) Int J Oncol , vol.43 , pp. 985-994
    • Piva, R.1    Spandidos, D.A.2    Gambari, R.3
  • 97
    • 84883360050 scopus 로고    scopus 로고
    • Knockdown of Slug by RNAi inhibits the proliferation and invasion of HCT116 colorectal cancer cells
    • COI: 1:CAS:528:DC%2BC3sXhs1elsbzI, PID: 23900394
    • Qian J, Liu H, Chen W, Wen K, Lu W, Huang C, et al. Knockdown of Slug by RNAi inhibits the proliferation and invasion of HCT116 colorectal cancer cells. Mol Med Rep. 2013;8:1055–9.
    • (2013) Mol Med Rep , vol.8 , pp. 1055-1059
    • Qian, J.1    Liu, H.2    Chen, W.3    Wen, K.4    Lu, W.5    Huang, C.6
  • 98
    • 84874004871 scopus 로고    scopus 로고
    • Lentivirus-mediated shRNA interference targeting SLUG inhibits lung cancer growth and metastasis
    • PID: 23244088
    • Wang YP, Wang MZ, Luo YR, Shen Y, Wei ZX. Lentivirus-mediated shRNA interference targeting SLUG inhibits lung cancer growth and metastasis. Asian Pac J Cancer Prev. 2012;13:4947–51.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 4947-4951
    • Wang, Y.P.1    Wang, M.Z.2    Luo, Y.R.3    Shen, Y.4    Wei, Z.X.5
  • 99
    • 84864361751 scopus 로고    scopus 로고
    • Lentivirus-delivered ZEB-1 small interfering RNA inhibits lung adenocarcinoma cell growth in vitro and in vivo
    • COI: 1:CAS:528:DC%2BC38XhtVGht7vK, PID: 22481253
    • Liu Y, Yan X, Liu N, Zhou J, Liu J, Pang H, et al. Lentivirus-delivered ZEB-1 small interfering RNA inhibits lung adenocarcinoma cell growth in vitro and in vivo. J Cancer Res Clin Oncol. 2012;138:1329–38.
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 1329-1338
    • Liu, Y.1    Yan, X.2    Liu, N.3    Zhou, J.4    Liu, J.5    Pang, H.6
  • 100
    • 84858016877 scopus 로고    scopus 로고
    • Induction of ZEB proteins by inactivation of RB protein is key determinant of mesenchymal phenotype of breast cancer
    • COI: 1:CAS:528:DC%2BC38XjsFCktbk%3D, PID: 22262832
    • Arima Y, Hayashi H, Sasaki M, Hosonaga M, Goto TM, Chiyoda T, et al. Induction of ZEB proteins by inactivation of RB protein is key determinant of mesenchymal phenotype of breast cancer. J Biol Chem. 2012;287:7896–906.
    • (2012) J Biol Chem , vol.287 , pp. 7896-7906
    • Arima, Y.1    Hayashi, H.2    Sasaki, M.3    Hosonaga, M.4    Goto, T.M.5    Chiyoda, T.6
  • 101
    • 84861099981 scopus 로고    scopus 로고
    • Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma
    • COI: 1:CAS:528:DC%2BC38XmslKjtrs%3D, PID: 22213004
    • Shen A, Zhang Y, Yang H, Xu R, Huang G. Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma. J Surg Oncol. 2012;105:830–4.
    • (2012) J Surg Oncol , vol.105 , pp. 830-834
    • Shen, A.1    Zhang, Y.2    Yang, H.3    Xu, R.4    Huang, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.