Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential

Cell Death and Differentiation

Volumn 21, Issue 2, 2014, Pages 310-320

  De Craene, B ^a   Denecker, G ^a   Vermassen, P ^a   Taminau, J ^a   Mauch, C ^b   Derore, A ^a   Jonkers, J ^c   Fuchs, E ^d   Berx, G ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF COLOGNE   (Germany)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

EMT; skin cancer; Snail; stem cells

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; PROTEIN; PROTEIN FOXM1; PROTEIN P53; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL CARCINOMA; CANCER GROWTH; CARCINOGENESIS; CELL EXPANSION; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; EPIDERMIS CELL; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; INFANT; KERATINOCYTE; METASTASIS; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEBACEOUS CARCINOMA; SKIN CANCER; SQUAMOUS CELL CARCINOMA; STEM CELL; ANIMAL; CANCER STEM CELL; CELL DIFFERENTIATION; DISEASE COURSE; GENETICS; METABOLISM; PATHOLOGY; SEBACEOUS GLAND TUMOR; SKIN TUMOR; TRANSGENIC MOUSE;

GASTROPODA; MUS MUSCULUS;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; DISEASE PROGRESSION; HUMANS; MICE; MICE, TRANSGENIC; NEOPLASM METASTASIS; NEOPLASTIC STEM CELLS; SEBACEOUS GLAND NEOPLASMS; SKIN NEOPLASMS; TRANSCRIPTION FACTORS;

EID: 84892440278     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.148     Document Type: Article

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