메뉴 건너뛰기




Volumn 30, Issue 4, 2013, Pages

EMT transcription factors: Implication in osteosarcoma

Author keywords

Cancer therapy; Osteosarcoma; Snail; Twist; Zeb

Indexed keywords

CISPLATIN; DOXORUBICIN; FIBULIN 5; GELATINASE B; MESSENGER RNA; METHOTREXATE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR ZEB1; UVOMORULIN; ANTINEOPLASTIC AGENT; TRANSCRIPTION FACTOR;

EID: 84882400809     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-013-0697-2     Document Type: Review
Times cited : (122)

References (53)
  • 1
    • 77953669219 scopus 로고    scopus 로고
    • The epidemiology of osteosarcoma
    • 20213383 10.1007/978-1-4419-0284-9-1
    • Ottaviani G, Jaffe N. The epidemiology of osteosarcoma. Cancer Treat Res. 2009;152:3-13.
    • (2009) Cancer Treat Res , vol.152 , pp. 3-13
    • Ottaviani, G.1    Jaffe, N.2
  • 2
    • 63449118087 scopus 로고    scopus 로고
    • Osteosarcoma incidence and survival rates from 1973 to 2004: Data from the surveillance, epidemiology, and end results program
    • 19197972 10.1002/cncr.24121
    • Mirabello L, Troisi RJ, Savage SA. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the surveillance, epidemiology, and end results program. Cancer. 2009;115:1531-43.
    • (2009) Cancer , vol.115 , pp. 1531-1543
    • Mirabello, L.1    Troisi, R.J.2    Savage, S.A.3
  • 5
    • 33846882630 scopus 로고    scopus 로고
    • Molecular pathogenesis of osteosarcoma
    • DOI 10.1089/dna.2006.0505
    • Kansara M, Thomas DM. Molecular pathogenesis of osteosarcoma. DNA Cell Biol. 2007;26:1-18. (Pubitemid 46219587)
    • (2007) DNA and Cell Biology , vol.26 , Issue.1 , pp. 1-18
    • Kansara, M.1    Thomas, D.M.2
  • 6
    • 0035033404 scopus 로고    scopus 로고
    • Current treatment of osteosarcoma
    • DOI 10.1081/CNV-100102557
    • Ferguson WS, Goorin AM. Current treatment of osteosarcoma. Cancer Invest. 2001;19:292-315. (Pubitemid 32374371)
    • (2001) Cancer Investigation , vol.19 , Issue.3 , pp. 292-315
    • Ferguson, W.S.1    Goorin, A.M.2
  • 8
    • 31744450019 scopus 로고    scopus 로고
    • Management of osteosarcoma pulmonary metastases
    • DOI 10.1053/j.sempedsurg.2005.11.005, PII S1055858605000909, Childhood Cancer
    • Harting MT, Blakely ML. Management of osteosarcoma pulmonary metastases. Semin Pediatr Surg. 2006;15:25-9. (Pubitemid 43177159)
    • (2006) Seminars in Pediatric Surgery , vol.15 , Issue.1 , pp. 25-29
    • Harting, M.T.1    Blakely, M.L.2
  • 9
    • 79955524738 scopus 로고    scopus 로고
    • Molecular alterations as target for therapy in metastatic osteosarcoma: A review of literature
    • 21461590 10.1007/s10585-011-9384-x 1:CAS:528:DC%2BC3MXltFCitrs%3D
    • PosthumaDeBoer J, Witlox MA, Kaspers GJ, van Royen BJ. Molecular alterations as target for therapy in metastatic osteosarcoma: a review of literature. Clin Exp Metastasis. 2011;28:493-503.
    • (2011) Clin Exp Metastasis , vol.28 , pp. 493-503
    • Posthumadeboer, J.1    Witlox, M.A.2    Kaspers, G.J.3    Van Royen, B.J.4
  • 10
    • 33749542027 scopus 로고    scopus 로고
    • The biology of metastases in pediatric sarcomas
    • Krishnan K, Khanna C, Helman LJ. The biology of metastases in pediatric sarcomas. Cancer J. 2005;11:306-13. (Pubitemid 44698797)
    • (2005) Cancer Journal , vol.11 , Issue.4 , pp. 306-313
    • Krishnan, K.1    Khanna, C.2    Helman, L.J.3
  • 11
    • 79953689605 scopus 로고    scopus 로고
    • Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-phenotypic cells: Are they cousins or twins?
    • 10.3390/cancers30100716
    • Kong D, Li Y, Wang Z, Sarkar FH. Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-phenotypic cells: are they cousins or twins? Cancers (Basel). 2011;3:716-29.
    • (2011) Cancers (Basel) , vol.3 , pp. 716-729
    • Kong, D.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 12
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: New insights in signaling, development, and disease
    • 16567498 10.1083/jcb.200601018 1:CAS:528:DC%2BD28XjtF2qsLs%3D
    • Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol. 2006;172:973-81.
    • (2006) J Cell Biol , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3    Thompson, E.W.4
  • 13
    • 84860367807 scopus 로고    scopus 로고
    • What is bad in cancer is good in the embryo: Importance of EMT in neural crest development
    • 22430756 10.1016/j.semcdb.2012.03.010 1:CAS:528:DC%2BC38XmslyhtLw%3D
    • Kerosuo L, Bronner-Fraser M. What is bad in cancer is good in the embryo: importance of EMT in neural crest development. Semin Cell Dev Biol. 2012;23:320-32.
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 320-332
    • Kerosuo, L.1    Bronner-Fraser, M.2
  • 14
    • 84885424897 scopus 로고    scopus 로고
    • Twist: A molecular target in cancer therapeutics
    • Online published
    • Khan MA, Chen HC, Zhang D, Fu J. Twist: a molecular target in cancer therapeutics, Tumor Biol. 2013; Online published.
    • (2013) Tumor Biol
    • Khan, M.A.1    Chen, H.C.2    Zhang, D.3    Fu, J.4
  • 17
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • 19945376 10.1016/j.cell.2009.11.007 1:CAS:528:DC%2BC3cXksFWltA%3D%3D
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell. 2009;139:871-90.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 18
    • 34249289041 scopus 로고    scopus 로고
    • Snail, ZEB and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • DOI 10.1038/nrc2131, PII NRC2131
    • Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer. 2007;7:415-28. (Pubitemid 46809165)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.6 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 19
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • 23344542 10.1038/nrc3447
    • De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer. 2013;13:97-110.
    • (2013) Nat Rev Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 20
    • 84880257210 scopus 로고    scopus 로고
    • Prognostic value of Twist and E-cadherin in patients with osteosarcoma
    • 22847601 10.1007/s12032-012-0317-6 1:CAS:528:DC%2BC38XhslCntr3E
    • Yin K, Liao Q, He H, Zhong D. Prognostic value of Twist and E-cadherin in patients with osteosarcoma. Med Oncol. 2012;29:3449-55.
    • (2012) Med Oncol , vol.29 , pp. 3449-3455
    • Yin, K.1    Liao, Q.2    He, H.3    Zhong, D.4
  • 21
    • 84868467012 scopus 로고    scopus 로고
    • Regulators of skeletal development: A cluster analysis of 206 bone tumors reveals diagnostically useful markers
    • 22766796 10.1038/modpathol.2012.110 1:CAS:528:DC%2BC38Xhs1arsrnN
    • Horvai AE, Roy R, Borys D, O'Donnell RJ. Regulators of skeletal development: a cluster analysis of 206 bone tumors reveals diagnostically useful markers. Mod Pathol. 2012;25:1452-61.
    • (2012) Mod Pathol , vol.25 , pp. 1452-1461
    • Horvai, A.E.1    Roy, R.2    Borys, D.3    O'Donnell, R.J.4
  • 22
    • 0037462477 scopus 로고    scopus 로고
    • Twist regulates cytokine gene expression through a negative feedback loop that represses NF-κB activity
    • DOI 10.1016/S0092-8674(03)00002-3
    • Šošić D, Richardson JA, Yu K, Ornitz DM, Olson EN. Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell. 2003;112:169-80. (Pubitemid 36144107)
    • (2003) Cell , vol.112 , Issue.2 , pp. 169-180
    • Sosic, D.1    Richardson, J.A.2    Yu, K.3    Ornitz, D.M.4    Olson, E.N.5
  • 25
    • 84878969535 scopus 로고    scopus 로고
    • TWIST interacts with β-catenin signaling on osteosarcoma cell survival against cisplatin
    • Online published
    • Wu J, Liao Q, He H, Zhong D, Yin K. TWIST interacts with β-catenin signaling on osteosarcoma cell survival against cisplatin. Mol Carcinog. 2012; Online published.
    • (2012) Mol Carcinog
    • Wu, J.1    Liao, Q.2    He, H.3    Zhong, D.4    Yin, K.5
  • 26
    • 84872691828 scopus 로고    scopus 로고
    • TWIST interacts with endothelin-1/endothelin A receptor signaling in osteosarcoma cell survival against cisplatin
    • 23426781 1:CAS:528:DC%2BC3sXlt1Wnt7k%3D
    • Zhou Y, Zang X, Huang Z, Zhang C. TWIST interacts with endothelin-1/endothelin A receptor signaling in osteosarcoma cell survival against cisplatin. Oncol Lett. 2013;5:857-61.
    • (2013) Oncol Lett , vol.5 , pp. 857-861
    • Zhou, Y.1    Zang, X.2    Huang, Z.3    Zhang, C.4
  • 27
    • 33744927706 scopus 로고    scopus 로고
    • Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-κB in human osteosarcoma
    • DOI 10.1042/CS20050286
    • Felx M, Guyot MC, Isler M, Turcotte RE, Doyon J, Khatib AM, Leclerc S, Moreau A, Moldovan F. Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-kappaB in human osteosarcoma. Clin Sci (Lond). 2006;110:645-54. (Pubitemid 43844734)
    • (2006) Clinical Science , vol.110 , Issue.6 , pp. 645-654
    • Felx, M.1    Guyot, M.-C.2    Isler, M.3    Turcotte, R.E.4    Doyon, J.5    Khatib, A.-M.6    Leclerc, S.7    Moreau, A.8    Moldovan, F.9
  • 28
    • 67649449918 scopus 로고    scopus 로고
    • Negative regulation of TIMP1 is mediated by transcription factor TWIST1
    • 19513566 1:CAS:528:DC%2BD1MXosFSlsrY%3D
    • Okamura H, Yoshida K, Haneji T. Negative regulation of TIMP1 is mediated by transcription factor TWIST1. Int J Oncol. 2009;35:181-6.
    • (2009) Int J Oncol , vol.35 , pp. 181-186
    • Okamura, H.1    Yoshida, K.2    Haneji, T.3
  • 30
    • 0034680368 scopus 로고    scopus 로고
    • Snail/slug family of repressors: Slowly going into the fast lane of development and cancer
    • 11054563 10.1016/S0378-1119(00)00371-1 1:CAS:528:DC%2BD3cXovFSrsLs%3D
    • Hemavathy K, Ashraf SI, Ip YT. Snail/slug family of repressors: slowly going into the fast lane of development and cancer. Gene. 2000;257:1-12.
    • (2000) Gene , vol.257 , pp. 1-12
    • Hemavathy, K.1    Ashraf, S.I.2    Ip, Y.T.3
  • 31
    • 2342431153 scopus 로고    scopus 로고
    • The transcription factor Snail downregulates the tight junction components independently of E-cadherin downregulation
    • DOI 10.1242/jcs.01004
    • Ohkubo T, Ozawa M. The transcription factor Snail downregulates the tight junction components independently of E-cadherin downregulation. Cell Sci. 2004;117:1675-85. (Pubitemid 38559300)
    • (2004) Journal of Cell Science , vol.117 , Issue.9 , pp. 1675-1685
    • Ohkubo, T.1    Ozawa, M.2
  • 32
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • 10655587 10.1038/35000034 1:CAS:528:DC%2BD3cXhtVyltLo%3D
    • Batlle E, Sancho E, Francí C, Domínguez D, Monfar M, Baulida J, García De Herreros A. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol. 2000;2:84-9.
    • (2000) Nat Cell Biol , vol.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Francí, C.3    Domínguez, D.4    Monfar, M.5    Baulida, J.6    García De Herreros, A.7
  • 33
  • 34
    • 80051677041 scopus 로고    scopus 로고
    • Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer
    • 21858154 10.1371/journal.pone.0023524 1:CAS:528:DC%2BC3MXhtFGhtLbF
    • Larriba MJ, Ordóñez-Morán P, Chicote I, Martín-Fernández G, Puig I, Muñoz A, Pálmer HG. Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer. PLoS One. 2011;6:e23524.
    • (2011) PLoS One , vol.6 , pp. 23524
    • Larriba, M.J.1    Ordóñez-Morán, P.2    Chicote, I.3    Martín-Fernández, G.4    Puig, I.5    Muñoz, A.6    Pálmer, H.G.7
  • 35
    • 84870541317 scopus 로고    scopus 로고
    • Using components of the vitamin D pathway to prevent and treat colon cancer
    • 23206285 10.1111/j.1753-4887.2012.00522.x
    • Stubbins RE, Hakeem A, Núñez NP. Using components of the vitamin D pathway to prevent and treat colon cancer. Nutr Rev. 2012;70:721-9.
    • (2012) Nutr Rev , vol.70 , pp. 721-729
    • Stubbins, R.E.1    Hakeem, A.2    Núñez, N.P.3
  • 37
    • 63849130585 scopus 로고    scopus 로고
    • Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers
    • 10.2741/3433
    • Alves CC, Carneiro F, Hoefler H, Becker KF. Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers. Front Biosci. 2009;14:3035-50.
    • (2009) Front Biosci , vol.14 , pp. 3035-3050
    • Alves, C.C.1    Carneiro, F.2    Hoefler, H.3    Becker, K.F.4
  • 38
    • 79960631940 scopus 로고    scopus 로고
    • Expression of Snail2 in long bone osteosarcomas correlates with tumour malignancy
    • 10.1007/s13277-010-0146-1 1:CAS:528:DC%2BC3MXlvFOjsbY%3D
    • Sharili AS, Allen S, Smith K, Hargreaves J, Price J, McGonnell I. Expression of Snail2 in long bone osteosarcomas correlates with tumour malignancy. Tumor Biol. 2011;32:515-26.
    • (2011) Tumor Biol , vol.32 , pp. 515-526
    • Sharili, A.S.1    Allen, S.2    Smith, K.3    Hargreaves, J.4    Price, J.5    McGonnell, I.6
  • 39
    • 72449129934 scopus 로고    scopus 로고
    • Regulation of bone development and extracellular matrix protein genes by RUNX2
    • 19649655 10.1007/s00441-009-0832-8 1:CAS:528:DC%2BD1MXhsVymtrbI
    • Komori T. Regulation of bone development and extracellular matrix protein genes by RUNX2. Cell Tissue Res. 2010;339:189-95.
    • (2010) Cell Tissue Res , vol.339 , pp. 189-195
    • Komori, T.1
  • 40
    • 33846038681 scopus 로고    scopus 로고
    • Osteosarcoma and osteoblastic differentiation: A new perspective on oncogenesis
    • DOI 10.1097/BLO.0b013e31802b683c, PII 0000308620070100000039
    • Haydon RC, Luu HH, He TC. Osteosarcoma and osteoblastic differentiation: a new perspective on oncogenesis. Clin Orthop Relat Res. 2007;454:237-46. (Pubitemid 46066041)
    • (2007) Clinical Orthopaedics and Related Research , Issue.454 , pp. 237-246
    • Haydon, R.C.1    Luu, H.H.2    He, T.-C.3
  • 41
    • 63049101157 scopus 로고    scopus 로고
    • The role of the ZEB family of transcription factors in development and disease
    • 19011757 10.1007/s00018-008-8465-8 1:CAS:528:DC%2BD1MXisVOku7k%3D
    • Vandewalle C, Van Roy F, Berx G. The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci. 2009;66:773-87.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 773-787
    • Vandewalle, C.1    Van Roy, F.2    Berx, G.3
  • 42
    • 84864360562 scopus 로고    scopus 로고
    • Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
    • 22349261 10.1007/s00018-012-0935-3 1:CAS:528:DC%2BC38XhtVansbbP
    • Gheldof A, Hulpiau P, van Roy F, De Craene B, Berx G. Evolutionary functional analysis and molecular regulation of the ZEB transcription factors. Cell Mol Life Sci. 2012;69:2527-41.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 2527-2541
    • Gheldof, A.1    Hulpiau, P.2    Van Roy, F.3    De Craene, B.4    Berx, G.5
  • 43
    • 77950502330 scopus 로고    scopus 로고
    • ZEB proteins link cell motility with cell cycle control and cell survival in cancer
    • 20160487 10.4161/cc.9.5.10839 1:CAS:528:DC%2BC3cXht12ktb%2FL
    • Browne G, Sayan AE, Tulchinsky E. ZEB proteins link cell motility with cell cycle control and cell survival in cancer. Cell Cycle. 2010;9:886-91.
    • (2010) Cell Cycle , vol.9 , pp. 886-891
    • Browne, G.1    Sayan, A.E.2    Tulchinsky, E.3
  • 45
    • 33748116186 scopus 로고    scopus 로고
    • A Transient, EMT-Linked Loss of Basement Membranes Indicates Metastasis and Poor Survival in Colorectal Cancer
    • DOI 10.1053/j.gastro.2006.06.016, PII S0016508506012868
    • Spaderna S, Schmalhofer O, Hlubek F, Berx G, Eger A, Merkel S, Jung A, Kirchner T, Brabletz T. A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology. 2006;131:830-40. (Pubitemid 44307069)
    • (2006) Gastroenterology , vol.131 , Issue.3 , pp. 830-840
    • Spaderna, S.1    Schmalhofer, O.2    Hlubek, F.3    Berx, G.4    Eger, A.5    Merkel, S.6    Jung, A.7    Kirchner, T.8    Brabletz, T.9
  • 47
    • 80054073802 scopus 로고    scopus 로고
    • RLIM interacts with Smurf2 and promotes TGF-β induced U2OS cell migration
    • 21945933 10.1016/j.bbrc.2011.09.053 1:CAS:528:DC%2BC3MXhtlaks7bJ
    • Huang Y, Yang Y, Gao R, Yang X, Yan X, Wang C, Jiang S, Yu L. RLIM interacts with Smurf2 and promotes TGF-β induced U2OS cell migration. Biochem Biophys Res Commun. 2011;414:181-5.
    • (2011) Biochem Biophys Res Commun , vol.414 , pp. 181-185
    • Huang, Y.1    Yang, Y.2    Gao, R.3    Yang, X.4    Yan, X.5    Wang, C.6    Jiang, S.7    Yu, L.8
  • 48
    • 84861099981 scopus 로고    scopus 로고
    • Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma
    • 22213004 10.1002/jso.23012 1:CAS:528:DC%2BC38XmslKjtrs%3D
    • Shen A, Zhang Y, Yang H, Xu R, Huang G. Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma. J Surg Oncol. 2012;105:830-4.
    • (2012) J Surg Oncol , vol.105 , pp. 830-834
    • Shen, A.1    Zhang, Y.2    Yang, H.3    Xu, R.4    Huang, G.5
  • 50
    • 70349614360 scopus 로고    scopus 로고
    • Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors
    • 19771160 10.1371/journal.pone.0007133
    • Wensman H, Heldin NE, Pejler G, Hellmén E. Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors. PLoS One. 2009;4:e7133.
    • (2009) PLoS One , vol.4 , pp. 7133
    • Wensman, H.1    Heldin, N.E.2    Pejler, G.3    Hellmén, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.