Short interfering RNA directed against TWIST, a novel zinc finger transcription factor, increases A549 cell sensitivity to cisplatin via MAPK/mitochondrial pathway

Biochemical and Biophysical Research Communications

Volumn 369, Issue 4, 2008, Pages 1098-1102

  Zhuo, Wen Lei ^a   Wang, Yan ^a   Zhuo, Xian Lu ^a   Zhang, Yun Song ^b   Chen, Zheng Tang ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cisplatin; Epithelial mesenchymal transition; MAPKs; Mitochondrial pathway; Non small cell lung cancer; RNA interference; Sensitivity; TWIST

Indexed keywords

CISPLATIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR TWIST; ZINC FINGER PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL; CARCINOGENICITY; CELL VIABILITY; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; LUNG CANCER; MESENCHYME CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; DRUG RESISTANCE, NEOPLASM; GENETIC VECTORS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; NUCLEAR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TWIST TRANSCRIPTION FACTOR; ZINC FINGERS;

EID: 41149143022     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.02.143     Document Type: Article

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