Identification and Validation of the Methylated TWIST1 and NID2 Genes through Real-Time Methylation-Specific Polymerase Chain Reaction Assays for the Noninvasive Detection of Primary Bladder Cancer in Urine Samples

European Urology

Volumn 58, Issue 1, 2010, Pages 96-104

  Renard, Isabelle ^a   Joniau, Steven ^b   van Cleynenbreugel, Ben ^b   Collette, Catherine ^a   Naômé, Christophe ^a   Vlassenbroeck, Ilse ^a   Nicolas, Hubert ^c   de Leval, Jean ^d   Straub, Josef ^a   Van Criekinge, Wim ^a   Hamida, Wissem ^d   Hellel, Majed ^d   Thomas, Alexandre ^d   de Leval, Laurence ^d,e   Bierau, Katja ^a   Waltregny, David ^d,e  

^a OncoMethylome Sciences SA   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c Centre Hospitalier Regional de La Citadelle   (Belgium)

^d UNIVERSITY OF LIÈGE   (Belgium)

^e UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Bladder cancer; Cytology; Gene promoter; Methylation; PCR; Urine

Indexed keywords

BETA ACTIN; GENOMIC DNA; NID2 PROTEIN; PROTEIN; TWIST1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BLADDER CANCER; CANCER DIAGNOSIS; CANCER GRADING; CANCER STAGING; CANCER TISSUE; CONTROLLED STUDY; CYTOLOGY; DNA EXTRACTION; DNA METHYLATION; GENE IDENTIFICATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MARKER GENE; NON INVASIVE MEASUREMENT; PRIMARY TUMOR; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; URINALYSIS;

ACTINS; ADULT; AGED; AGED, 80 AND OVER; CELL ADHESION MOLECULES; CELL LINE, TUMOR; DNA METHYLATION; DNA, NEOPLASM; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL; TWIST TRANSCRIPTION FACTOR; URINARY BLADDER NEOPLASMS;

EID: 77952883763     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2009.07.041     Document Type: Article

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