Comprehensive DNA adduct analysis reveals pulmonary inflammatory response contributes to genotoxic action of magnetite nanoparticles

International Journal of Molecular Sciences

Volumn 16, Issue 2, 2015, Pages 3474-3492

  Ishino, Kousuke ^a   Kato, Tatsuya ^a   Kato, Mamoru ^a   Shibata, Tatsuhiro ^a   Watanabe, Masatoshi ^b   Wakabayashi, Keiji ^c   Nakagama, Hitoshi ^a   Totsuka, Yukari ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b YOKOHAMA NATIONAL UNIVERSITY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

DNA adductome; Intratracheal instillation; Magnetite nanoparticle; Pulmonary inflammation

Indexed keywords

DEOXYCYTIDINE; MAGNETITE NANOPARTICLE; CONTRAST MEDIUM; DNA ADDUCT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DETERMINATION; DNA MODIFICATION; GENOTOXICITY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRINCIPAL COMPONENT ANALYSIS; ANALYSIS; ANIMAL; CHEMICALLY INDUCED; CHEMISTRY; DNA DAMAGE; DRUG EFFECTS; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; LUNG; METABOLISM;

MUS;

ANIMALS; CONTRAST MEDIA; DEOXYCYTIDINE; DNA ADDUCTS; DNA DAMAGE; LUNG; MAGNETITE NANOPARTICLES; MALE; MICE; MICE, INBRED ICR; PNEUMONIA; PRINCIPAL COMPONENT ANALYSIS;

EID: 84922375980     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms16023474     Document Type: Article

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