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Volumn 4, Issue 1, 2014, Pages 175-188

Magnetite nanoparticles induce genotoxicity in the lungs of mice via inflammatory response

Author keywords

DNA damage; Genotoxicity; Intratracheal instillation; Magnetite nanoparticle (MGT); Pulmonary inflammation

Indexed keywords


EID: 84922364745     PISSN: None     EISSN: 20794991     Source Type: Journal    
DOI: 10.3390/nano4010175     Document Type: Article
Times cited : (31)

References (36)
  • 2
    • 84855824016 scopus 로고    scopus 로고
    • Nanoparticles: A boon to drug delivery, therapeutics, diagnostics and imaging
    • Parveen, S.; Misra, R.; Sahoo, S.K. Nanoparticles: A boon to drug delivery, therapeutics, diagnostics and imaging. Nanomedicine 2012, 8, 147–166.
    • (2012) Nanomedicine , vol.8 , pp. 147-166
    • Parveen, S.1    Misra, R.2    Sahoo, S.K.3
  • 3
    • 84866656031 scopus 로고    scopus 로고
    • Iron oxide-based nanostructures for MRI and magnetic hyperthermia
    • Hilger, I.; Kaiser, W.A. Iron oxide-based nanostructures for MRI and magnetic hyperthermia. Nanomedicine 2012, 7, 1443–1459.
    • (2012) Nanomedicine , vol.7 , pp. 1443-1459
    • Hilger, I.1    Kaiser, W.A.2
  • 6
    • 34250769487 scopus 로고    scopus 로고
    • Monodisperse magnetic nanoparticles for biomedical applications
    • Xu, C.J.; Sun, S.H. Monodisperse magnetic nanoparticles for biomedical applications. Polym. Int. 2007, 56, 821–826.
    • (2007) Polym. Int , vol.56 , pp. 821-826
    • Xu, C.J.1    Sun, S.H.2
  • 7
    • 84863513540 scopus 로고    scopus 로고
    • Cytotoxicity and genotoxicity of nanosized and microsized titanium dioxide and iron oxide particles in Syrian hamster embryo cells
    • Guichard, Y.; Schmit, J.; Darne, C.; Gaté, L.; Goutet, M.; Rousset, D.; Rastoix, O.; Wrobel, R.; Witschger, O.; Martin, A.; et al. Cytotoxicity and genotoxicity of nanosized and microsized titanium dioxide and iron oxide particles in Syrian hamster embryo cells. Ann. Occup. Hyg. 2012, 56, 631–644.
    • (2012) Ann. Occup. Hyg , vol.56 , pp. 631-644
    • Guichard, Y.1    Schmit, J.2    Darne, C.3    Gaté, L.4    Goutet, M.5    Rousset, D.6    Rastoix, O.7    Wrobel, R.8    Witschger, O.9    Martin, A.10
  • 8
    • 84873916492 scopus 로고    scopus 로고
    • Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: A quantitative method for oxidative stress assessment of nanoparticle-treated cells
    • Aranda, A.; Sequedo, L.; Tolosa, L.; Quintas, G.; Burello, E.; Castell, J.V.; Gombau, L. Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: A quantitative method for oxidative stress assessment of nanoparticle-treated cells. Toxicol. Vitro 2013, 27, 954–963.
    • (2013) Toxicol. Vitro , vol.27 , pp. 954-963
    • Aranda, A.1    Sequedo, L.2    Tolosa, L.3    Quintas, G.4    Burello, E.5    Castell, J.V.6    Gombau, L.7
  • 9
    • 78649904711 scopus 로고    scopus 로고
    • Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION)
    • Singh, N.; Jenkins, G.J.; Asadi, R.; Doak, S.H. Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION). Nano Rev. 2010, 1, 5358–5373.
    • (2010) Nano Rev , vol.1 , pp. 5358-5373
    • Singh, N.1    Jenkins, G.J.2    Asadi, R.3    Doak, S.H.4
  • 12
    • 67349144664 scopus 로고    scopus 로고
    • Size-dependent toxicity of metal oxide particles—A comparison between nano-and micrometer size
    • Karlsson, H.L.; Gustafsson, J.; Cronholm, P.; Möller, L. Size-dependent toxicity of metal oxide particles—A comparison between nano-and micrometer size. Toxicol. Lett. 2009, 188, 112–118.
    • (2009) Toxicol. Lett , vol.188 , pp. 112-118
    • Karlsson, H.L.1    Gustafsson, J.2    Cronholm, P.3    Möller, L.4
  • 16
    • 84860237913 scopus 로고    scopus 로고
    • Potential toxic effects of iron oxide nanoparticles in in vivo and in vitro experiments
    • Szalay, B.; Tátrai, E.; Nyírő, G.; Vezér, T.; Dura, G. Potential toxic effects of iron oxide nanoparticles in in vivo and in vitro experiments. J. Appl. Toxicol. 2012, 32, 446–453.
    • (2012) J. Appl. Toxicol , vol.32 , pp. 446-453
    • Szalay, B.1    Tátrai, E.2    Nyírő, G.3    Vezér, T.4    Dura, G.5
  • 18
    • 84880143893 scopus 로고    scopus 로고
    • Genotoxicity and reactive oxygen species production induced by magnetite nanoparticles in mammalian cells
    • Kawanishi, M.; Ogo, S.; Ikemoto, M.; Totsuka, Y.; Ishino, K.; Wakabayahsi, K.; Yagi, T. Genotoxicity and reactive oxygen species production induced by magnetite nanoparticles in mammalian cells. J. Toxicol. Sci. 2013, 38, 503–511.
    • (2013) J. Toxicol. Sci , vol.38 , pp. 503-511
    • Kawanishi, M.1    Ogo, S.2    Ikemoto, M.3    Totsuka, Y.4    Ishino, K.5    Wakabayahsi, K.6    Yagi, T.7
  • 19
    • 77954818793 scopus 로고    scopus 로고
    • Inflammatory responses may be induced by a single intratracheal instillation of iron nanoparticles in mice
    • Park, E.J.; Kim, H.; Kim, Y.; Yi, J.; Choi, K.; Park, K. Inflammatory responses may be induced by a single intratracheal instillation of iron nanoparticles in mice. Toxicology 2010, 275, 65–71.
    • (2010) Toxicology , vol.275 , pp. 65-71
    • Park, E.J.1    Kim, H.2    Kim, Y.3    Yi, J.4    Choi, K.5    Park, K.6
  • 20
    • 0030344622 scopus 로고    scopus 로고
    • Mutational spectra in transgenic animal research: Data analysis and study design based upon the mutant or mutation frequency
    • Carr, G.J.; Gorelick, N.J. Mutational spectra in transgenic animal research: Data analysis and study design based upon the mutant or mutation frequency. Environ. Mol. Mutagen. 1996, 28, 405–413.
    • (1996) Environ. Mol. Mutagen , vol.28 , pp. 405-413
    • Carr, G.J.1    Gorelick, N.J.2
  • 24
    • 0032584107 scopus 로고    scopus 로고
    • Oxidized, deaminated cytosines are a source of C → T transitions in vivo
    • Kreutzer, D.A.; Essigmann, J.M. Oxidized, deaminated cytosines are a source of C → T transitions in vivo. Proc. Natl. Acad. Sci. USA 1998, 95, 3578–3582.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3578-3582
    • Kreutzer, D.A.1    Essigmann, J.M.2
  • 25
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird, A.P. CpG-rich islands and the function of DNA methylation. Nature 1986, 321, 209–213.
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 26
    • 0025981359 scopus 로고
    • Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
    • Shibutani, S.; Takeshita, M.; Grollman, A.P. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 1991, 349, 431–434.
    • (1991) Nature , vol.349 , pp. 431-434
    • Shibutani, S.1    Takeshita, M.2    Grollman, A.P.3
  • 27
    • 0027399969 scopus 로고
    • Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-Oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells
    • Moriya, M. Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-Oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells. Proc. Natl. Acad. Sci. USA 1993, 90, 1122–1126.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1122-1126
    • Moriya, M.1
  • 28
    • 33748654795 scopus 로고    scopus 로고
    • Translesion DNA Synthesis across the heptanone-etheno-2′-deoxycytidine adduct in cells
    • Pollack, M.; Yang, I.Y.; Kim, H.Y.; Blair, I.A.; Moriya, M. Translesion DNA Synthesis across the heptanone-etheno-2′-deoxycytidine adduct in cells. Chem. Res. Toxicol. 2006, 19, 1074–1079.
    • (2006) Chem. Res. Toxicol , vol.19 , pp. 1074-1079
    • Pollack, M.1    Yang, I.Y.2    Kim, H.Y.3    Blair, I.A.4    Moriya, M.5
  • 29
    • 58649116940 scopus 로고    scopus 로고
    • Two distinct translesion synthesis pathways across a lipid peroxidation-derived DNA adduct in mammalian cells
    • Yang, I.Y.; Hashimoto, K.; de Wind, N.; Blair, I.A.; Moriya, M. Two distinct translesion synthesis pathways across a lipid peroxidation-derived DNA adduct in mammalian cells. J. Biol. Chem. 2009, 284, 191–198.
    • (2009) J. Biol. Chem , vol.284 , pp. 191-198
    • Yang, I.Y.1    Hashimoto, K.2    de Wind, N.3    Blair, I.A.4    Moriya, M.5
  • 30
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert, C.; Pétrilli, V.; van Bruggen, R.; Steele, C.; Mossman, B.T.; Tschopp, J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008, 320, 674–677.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Pétrilli, V.2    van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 32
    • 84862850519 scopus 로고    scopus 로고
    • Magnetic nanoparticles: An update of application for drug delivery and possible toxic effects
    • Kim, J.E.; Shin, J.Y.; Cho, M.H. Magnetic nanoparticles: An update of application for drug delivery and possible toxic effects. Arch. Toxicol. 2012, 86, 685–700.
    • (2012) Arch. Toxicol , vol.86 , pp. 685-700
    • Kim, J.E.1    Shin, J.Y.2    Cho, M.H.3
  • 33
    • 67349133162 scopus 로고    scopus 로고
    • Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance
    • Simberg, D.; Park, J.H.; Karmali, P.P.; Zhang, W.M.; Merkulov, S.; McCrae, K.; Bhatia, S.N.; Sailor, M.; Ruoslahti, E. Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance. Biomaterials 2009, 30, 3926–3933.
    • (2009) Biomaterials , vol.30 , pp. 3926-3933
    • Simberg, D.1    Park, J.H.2    Karmali, P.P.3    Zhang, W.M.4    Merkulov, S.5    McCrae, K.6    Bhatia, S.N.7    Sailor, M.8    Ruoslahti, E.9
  • 34
    • 84858340262 scopus 로고    scopus 로고
    • Subtle cytotoxicity and genotoxicity differences in superparamagnetic iron oxide nanoparticles coated with various functional groups
    • Hong, S.C.; Lee, J.H.; Lee, J.; Kim, H.Y.; Park, J.Y.; Cho, J.; Lee, J.; Han, D.W. Subtle cytotoxicity and genotoxicity differences in superparamagnetic iron oxide nanoparticles coated with various functional groups. Int. J. Nanomed. 2011, 6, 3219–3231.
    • (2011) Int. J. Nanomed , vol.6 , pp. 3219-3231
    • Hong, S.C.1    Lee, J.H.2    Lee, J.3    Kim, H.Y.4    Park, J.Y.5    Cho, J.6    Lee, J.7    Han, D.W.8
  • 36
    • 0034693862 scopus 로고    scopus 로고
    • Recent advances in the protocols of transgenic mouse mutation assays
    • Nohmi, T.; Suzuki, T.; Masumura, K. Recent advances in the protocols of transgenic mouse mutation assays. Mutat. Res. 2000, 455, 191–215.
    • (2000) Mutat. Res , vol.455 , pp. 191-215
    • Nohmi, T.1    Suzuki, T.2    Masumura, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.