Multiwalled carbon nanotubes induce a fibrogenic response by stimulating reactive oxygen species production, activating NF-κB signaling, and promoting fibroblast-to-myofibroblast transformation

Chemical Research in Toxicology

Volumn 24, Issue 12, 2011, Pages 2237-2248

  He, Xiaoqing ^a   Young, Shih Houng ^b   Schwegler Berry, Diane ^b   Chisholm, William P ^c   Fernback, Joseph E ^c   Ma, Qiang ^a  

^a Toxicology and Molecular Biology Branch   (United States)

^b Pathology and Physiology Research Branch   (United States)

^c NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MULTI WALLED NANOTUBE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; DNA BINDING; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG FIBROBLAST; MOUSE; MYOFIBROBLAST; NONHUMAN; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; CELL LINE; CHEMOKINES; CYTOKINES; FIBROBLASTS; FIBROSIS; HUMANS; MITOCHONDRIA; MYOFIBROBLASTS; NANOTUBES, CARBON; NF-KAPPA B; OXIDATIVE STRESS; PLATELET-DERIVED GROWTH FACTOR; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84055177567     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx200351d     Document Type: Article

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