Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry

Nature Protocols

Volumn 3, Issue 8, 2008, Pages 1287-1298

  Taghizadeh, Koli ^a   McFaline, Jose L ^a   Pang, Bo ^a,b,c   Sullivan, Matthew ^a   Dong, Min ^a,b,c   Plummer, Elaine ^a   Dedon, Peter C ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b ALNYLAM PHARMACEUTICALS   (United States)

^c Novartis Pharma AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DEOXYADENOSINE; DEOXYCYTIDINE; DEOXYINOSINE; DEOXYURIDINE; NUCLEOSIDE; RADIOISOTOPE; XANTHOSINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DEAMINATION; DILUTION; DNA DAMAGE; DNA DETERMINATION; DNA STRUCTURE; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID PEROXIDATION; LIQUID CHROMATOGRAPHY; NITROSATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY;

ANIMALS; BIOLOGICAL MARKERS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEAMINATION; DNA; DNA ADDUCTS; DNA DAMAGE; HUMANS; HYDROLYSIS; LIPID PEROXIDATION; MICE; OXIDATION-REDUCTION; PHOSPHORYLATION; TANDEM MASS SPECTROMETRY;

EID: 50349091399     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2008.119     Document Type: Article

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