Xin repeats define a novel actin-binding motif

Journal of Cell Science

Volumn 117, Issue 22, 2004, Pages 5257-5268

  Pacholsky, Dirk ^a   Vakeel, Padmanabhan ^a   Himmel, Mirko ^a   Löwe, Thomas ^a   Stradal, Theresia ^b   Rottner, Klemens ^b   Fürst, Dieter O ^a   van der Ven, Peter F M ^a  

^a UNIVERSITY OF POTSDAM   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Actin binding proteins; Focal adhesions; Repeats; Striated muscle; Xin

Indexed keywords

ACTIN BINDING PROTEIN; ALPHA ACTIN; MUSCLE PROTEIN; PROTEIN XIN; PROTEIN XIRP2; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; BINDING ASSAY; CELL CULTURE; CENTRIFUGATION; CONTROLLED STUDY; CYTOSKELETON; GENETIC TRANSFECTION; IN VITRO STUDY; MICROFILAMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; RAT; SKELETAL MUSCLE;

ACTINS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BETA CATENIN; BICYCLO COMPOUNDS, HETEROCYCLIC; CADHERINS; CELL LINE; CELL LINE, TUMOR; CIRCULAR DICHROISM; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; FOCAL ADHESIONS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; MUTATION; NUCLEAR PROTEINS; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; THIAZOLES; THIAZOLIDINES; TRANS-ACTIVATORS; TRANSFECTION; TROPOMYOSIN;

ANIMALIA;

EID: 9444250471     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01406     Document Type: Article

References (41)

1. Ballestrem, C., Wehrle-Haller, B. and Imhof, B. A. (1998). Actin dynamics in living mammalian cells. J. Cell Sci. 111, 1649-1658.
2. Burgstaller, G., Kranewitter, W. J. and Gimona, M. (2002). The molecular basis for the autoregulation of calponin by isoform-specifie C-terminal tail sequences. J. Cell Sci. 115, 2021-2029.
3. Cai, S., Liu, X., Glasser, A., Volberg, T., Filla, M., Geiger, B., Polansky, J. R. and Kaufman, P. L. (2000). Effect of latrunculin-A on morphology and actin-associated adhesions of cultured human trabecular meshwork cells. Mol. Vis. 6, 132-143.
4. Campbell, R. E., Tour, O., Palmer, A. E., Steinbach, P. A., Baird, G. S., Zacharias, A A. and Tsien, R. Y. (2002). A monomeric red fluorescent protein. Proc. Natl. Acad. Sci. USA 99, 7877-7882.
5. Carugo, K. D., Banuelos, S. and Saraste, M. (1997). Crystal structure of a calponin homology domain. Nat. Struct. Biol. 4, 175-179.
6. Chen, M. J., Shih, C. L. and Wang, K. (1993). Nebulin as an actin zipper. A two-module nebulin fragment promotes actin nucleation and stabilizes actin filaments. J. Biol. Chem. 268 20327-20334.
7. Coue, M., Brenner, S. L., Spector, I. and Korn, E. D. (1987). Inhibition of actin polymerization by latrunculin A. FEBS Lett. 213, 316-318.
8. Dlugosz, A. A., Antin, P. B., Nachmias, V. T. and Holtzer, H. (1984). The relationship between stress fiber-like structures and nascent myofibrils in cultured cardiac myocytes. J. Cell Biol. 99, 2268-2278.
9. Geeves, M. A. and Holmes, K. C. (1999). Structural mechanism of muscle contraction. Annu. Rev. Biochem. 68, 687-728.
10. Gimona, M. and Mital, R. (1998). The single CH domain of calponin is neither sufficient nor necessary for F-actin binding. J. Cell Sci. 111, 1813-1821.
11. Gimona, M. and Winder, S. J. (1998). Single calponin homology domains are not actin-binding domains. Curr. Biol. 8 R674-R675.
12. He, H., Watanabe, T., Zhan, X., Huang, C., Schuuring, E., Fukami, K., Takenawa, T., Kumar, C. C., Simpson, R. J. and Maruta, H. (1998). Role of phosphatidylinositol 4,5-bisphosphate in Ras/Rac-induced disruption of the cortactin-actomyosin II complex and malignant transformation. Mol. Cell. Biol. 18, 3829-3837.
13. Jin, J. P. and Wang, K. (1991). Cloning, expression, and protein interaction of human nebulin fragments composed of varying numbers of sequence modules. J. Biol. Chem. 266, 21215-21223.
14. Kostyukova, A., Maeda, K., Yamauchi, E., Krieger, I. and Maeda, Y. (2000). Domain structure of tropomodulin: distinct properties of the N-terminal and C-terminal halves. Eur. J. Biochem. 267, 6470-6475.
15. Kranewitter, W. J., Ylanne, J. and Gimona, M. (2001). UNC-87 is an actin-bundling protein. J. Biol. Chem. 276, 6306-6312.
16. Kruger, M., Wright, J. and Wang, K. (1991). Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile. J. Cell Biol. 115, 97-107.
17. Labeit, S., Gibson, T., Lakey, A., Leonard, K., Zeviani, M., Knight, P., Wardale, J. and Trinick, J. (1991). Evidence that nebulin is a protein-ruler in muscle thin filaments. FEBS Lett. 282, 313-316.
18. Lener, T., Burgstaller, G. and Gimona, M. (2004). The role of calponin in the gene profile of metastatic cells: inhibition of metastatic cell motility by multiple calponin repeats. FEBS Lett. 556, 221-226.
19. Lukoyanova, N., VanLoock, M. S., Orlova, A., Galkin, V. E., Wang, K. and Egelman, E. H. (2002). Each actin subunit has three nebulin binding sites: implications for steric blocking. Curr. Biol. 12, 383-388.
20. Morton, W. M., Ayscough, K. R. and McLaughlin, P. J. (2000). Latrunculin alters the actin-monomer subunit interface to prevent polymerization. Nat. Cell Biol. 2, 376-378.
21. Obermann, W. M. J., Gautel, M., Weber, K. and Fürst, D. O. (1997). Molecular structure of the sarcomeric M band: mapping of titin and myosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin. EMBO J. 16, 211-220.
22. Pace, C. N., Vajdos, F., Fee, L., Grimsley, G. and Gray, T. (1995). How to measure and predict the molar absorption coefficient of a protein. Protein Sci. 4, 2411-2423.
23. Pan, P. W., Li, K., Tuggle, C. K., Yu, M., Liu, B. and Zhao, S. H. (2003). Sequencing, tissue distribution and physical mapping of the porcine homologue of cardiomyopathy associated 3 (CMYA3). Anim. Genet. 34, 473-474.
24. Perry, S. V. (2001). Vertebrate tropomyosin: distribution, properties and function. J. Muscle Res. Cell Motil. 22, 5-49.
25. Pfuhl, M., Winder, S. J. and Pastore, A. (1994). Nebulin, a helical actin binding protein. EMBO J. 13, 1782-1789.
26. Pittenger, M. F., Kazzaz, J. A. and Helfman, D. M. (1994). Functional properties of non-muscle tropomyosin isoforms. Curr. Opin. Cell Biol. 6, 96-104.
27. Pollard, T. D. (1999). Introduction to actin and associated proteins. In Guidebook to the Cytoskeletal and Motor Proteins (ed. T. Kreis and R. Vale), pp. 3-11. Oxford, UK: Oxford University Press.
28. Ruppel, K. M. and Spudich, J. A. (1996). Structure-function analysis of the motor domain of myosin. Annu. Rev. Cell Dev. Biol. 12, 543-573.
29. Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A. and Arnheim, N. (1985). Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230, 1350-1354.
30. Schmitz, H. D. and Bereiter-Hahn, J. (2001). GFP associates with microfilaments in fixed cells. Histochem. Cell Biol. 116, 89-94.
31. Sinn, H. W., Balsamo, J., Lilien, J. and Lin, J. J. (2002). Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development. Dev. Dyn. 225, 1-13.
32. Spector, I., Shochet, N. R., Kashman, Y. and Groweiss, A. (1983). Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells. Science 219, 493-495.
33. Spudich, J. A. and Watt, S. (1971). The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J. Biol. Chem. 246, 4866-4871.
34. Steffen, A., Rottner, K., Ehinger, J., Innocenti, M., Scita, G., Wehland, J. and Stradal, T. E. B. (2004). Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. EMBO J. 23, 749-759.
35. Stradal, T., Kranewitter, W., Winder, S. J. and Gimona, M. (1998). CH domains revisited. FEBS Lett. 431, 134-137.
36. Trinick, J. (1994). Titin and nebulin: protein rulers in muscle? Trends Biochem. Sci. 19, 405-409.
37. Wang, A Z., Hu, X., Lin, J. L. C., Kitten, G. T., Solursh, M. and Lin, J. J. C. (1996a). Differential displaying of mRNAs from the atrioventricular region of developing chicken hearts at stages 15 and 21. Front. Biosci. 1, 1-15.
38. Wang, K., Knipfer, M., Huang, Q. Q., van Heerden, A., Hsu, L. C., Gutierrez, G., Quian, X. L. and Stedman, H. (1996b). Human skeletal muscle nebulin sequence encodes a blueprint for thin filament architecture. Sequence motifs and affinity profiles of tandem repeats and terminal SH3. J. Biol. Chem. 271, 4304-4314.
39. Wang, A Z., Reiter, R. S., Lin, J. L., Wang, Q., Williams, H. S., Kroh, S. L., Schultheiss, T. M., Evans, S. and Lin, J. J. (1999). Requirement of a novel gene, Xin, in cardiac morphogetiesis. Development 126, 1281-1294.
40. Weed, S. A., Karginov, A. V., Schafer, D. A., Weaver, A. M., Kinley, A. W., Cooper, J. A. and Parsons, J. T. (2000). Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J. Cell Biol. 151, 29-40.
41. Zamir, E., Katz, M., Posen, Y., Erez, N., Yamada, K. M., Katz, B. Z., Lin, S., Lin, A C., Bershadsky, A., Kam, Z. et al. (2000). Dynamics and segregation of cell-matrix adhesions in cultured fibroblasts. Nat. Cell Biol. 2, 191-196.