A new locus for autosomal recessive non-syndromal sensorineural hearing impairment (DFNB27) on chromosome 2q23-q31

European Journal of Human Genetics

Volumn 8, Issue 12, 2000, Pages 991-993

  Pulleyn, L J ^a   Jackson, A P ^a,b   Roberts, E ^a   Carridice, A ^a   Muxworthy, C ^a   Houseman, M ^a   Al Gazali, L I ^c   Lench, N J ^a   Markham, A F ^a   Mueller, R F ^b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^c UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Autozygosity mapping; Chromosome 2q; DFNA16; DFNB27; Heterogeneity; Homozygosity mapping; Locus

Indexed keywords

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHROMOSOME 2Q; CONSANGUINEOUS MARRIAGE; GENE LOCUS; GENE MAPPING; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENOTYPE; HUMAN; PERCEPTION DEAFNESS; PRIORITY JOURNAL; SYNDROME; UNITED ARAB EMIRATES;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 2; CONSANGUINITY; FEMALE; HEARING LOSS, SENSORINEURAL; HOMOZYGOTE; HUMANS; MALE; PEDIGREE;

EID: 17744397101     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200567     Document Type: Article

References (17)

1. Homozygosity mapping: A way to map human recessive traits with the DNA of inbred children
2. Faster sequential genetic linkage computations
3. Avoiding recomputation in linkage analysis
4. A gene for fluctuating, progressive autosomal dominant nonsyndromic hearing loss, DFNA16, maps to chromosome 2q23-24.3
5. A non-syndrome form of neurosensory, recessive deafness maps to the pericentromeric region of chromosome 13q
6. A gene responsible for a dominant form of neurosensory non-syndromic deafness maps to the NSRD1 recessive deafness gene interval
7. A human gene responsible for neurosensory, non-syndromic recessive deafness is a candidate homologue of the mouse sh-1gene
8. A gene for a dominant form of non-syndromic sensorineural deafness (DFNA11) maps within the region containing the DFNB2 recessive deafness gene
9. Connexin 26 mutations in hereditary non-syndromic sensorineural deafness
10. Connexin 26 gene linked to a dominant deafness
11. Mutations in the myosin VIIA gene cause non-syndromic recessive deafness
12. Autosomal dominant non-syndromic deafness caused by a mutation in the myosin VIIA gene
13. The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA gene
14. Mutations in the alpha-tectorin gene cause autosomal dominant non-syndromic hearing impairment
15. An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB2
16. Deafness linked to DFNA2: One locus but how many genes?
17. A second locus for familial generalized epilepsy with febrile seizures plus maps to chromosome 2q21-q33