Small heat shock proteins and the endoplasmic reticulum: Potential attractive therapeutic targets?

Current Molecular Medicine

Volumn 15, Issue 1, 2015, Pages 38-46

  Zeng, L ^a   Tan, J ^b   Lu, T ^a   Lei, Q ^a   Chen, C ^a   Hu, Z ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Apoptosis; Cancer; Cytoprotection; Endoplasmic reticulum (ER) stress; Small heat shock proteins (sHsps)

Indexed keywords

ALPHA CRYSTALLIN; BORTEZOMIB; CAVEOLIN 3; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DEXAMETHASONE; DOXORUBICIN; ENDOPLASMIC RETICULUM PROTEIN 29; GEMCITABINE; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN 20; HEAT SHOCK PROTEIN 27; HEAT SHOCK TRANSCRIPTION FACTOR 1; INITIATION FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN; PROTEIN BAK; PROTEIN BCL 2; SMALL HEAT SHOCK PROTEIN; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; HUMAN; LIPOGENESIS; NEOPLASM; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ANIMAL; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; MOUSE; NEOPLASMS; PATHOLOGY;

MAMMALIA;

ALPHA-CRYSTALLIN B CHAIN; ANIMALS; APOPTOSIS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK PROTEINS, SMALL; HUMANS; MICE; MOLECULAR TARGETED THERAPY; NEOPLASMS;

EID: 84922326874     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/1566524015666150114111745     Document Type: Article

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