Cotargeting stress-activated Hsp27 and autophagy as a combinatorial strategy to amplify endoplasmic reticular stress in prostate cancer

Molecular Cancer Therapeutics

Volumn 11, Issue 8, 2012, Pages 1661-1671

  Kumano, Masafumi ^a   Furukawa, Junya ^b   Shiota, Masaki ^a   Zardan, Anousheh ^a   Zhang, Fan ^a   Beraldi, Eliana ^a   Wiedmann, Romina M ^a   Fazli, Ladan ^a   Zoubeidi, Amina ^a   Gleave, Martin E ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CHLOROQUINE; HEAT SHOCK PROTEIN 27; OGX 427; PROTEASOME; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER GROWTH; CANCER INHIBITION; CELL PROTECTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN FUNCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CHLOROQUINE; DRUG SYNERGISM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENE SILENCING; HSP27 HEAT-SHOCK PROTEINS; HUMANS; LEUPEPTINS; MALE; OLIGONUCLEOTIDES, ANTISENSE; PROSTATIC NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; TUMOR BURDEN; UBIQUITIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84864882148     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-12-0072     Document Type: Article

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