Geranylgeranylacetone prevents acute liver damage after massive hepatectomy in rats through suppression of a CXC chemokine GRO1 and induction of heat shock proteins

Journal of Gastrointestinal Surgery

Volumn 13, Issue 1, 2009, Pages 66-73

  Kanemura, Hirofumi ^a   Kusumoto, Kenji ^a   Miyake, Hidenori ^a   Tashiro, Seiki ^a   Rokutan, Kazuhito ^a   Shimada, Mitsuo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Acute liver damage; Geranylgeranylacetone; Heat shock proteins; Massive hepatectomy

Indexed keywords

ANTIULCER AGENT; CXCL1 CHEMOKINE; CXCL1 PROTEIN, RAT; DITERPENE; HEAT SHOCK PROTEIN 70; RNA; TEPRENONE;

ANIMAL; ARTICLE; AUTORADIOGRAPHY; COMPARATIVE STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION; GENETICS; LIVER FAILURE; LIVER RESECTION; MALE; METABOLISM; MICROARRAY ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT;

ANIMALS; ANTI-ULCER AGENTS; AUTORADIOGRAPHY; BLOTTING, WESTERN; CHEMOKINE CXCL1; DISEASE MODELS, ANIMAL; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HEPATECTOMY; HSP70 HEAT-SHOCK PROTEINS; LIVER FAILURE, ACUTE; MALE; MICROARRAY ANALYSIS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 57849122454     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-008-0604-x     Document Type: Article

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