Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead

Toxicology

Volumn 264, Issue 3, 2009, Pages 215-224

  Stacchiotti, Alessandra ^a   Morandini, Fausta ^b   Bettoni, Francesca ^b   Schena, Ilaria ^b   Lavazza, Antonio ^c   Grigolato, Pier Giovanni ^d   Apostoli, Pietro ^b   Rezzani, Rita ^a   Aleo, Maria Francesca ^b  

^a School of Medicine   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA LOMBARDIA E DELL EMILIA ROMAGNA   (Italy)

^d Spedali Civili   (Italy)

Author keywords

Hg(II); Nephrotoxicity; NRK 52E; Oxidative stress; Pb(II); Stress proteins

Indexed keywords

GLUCOSE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 72; INORGANIC COMPOUND; LEAD; MERCURY; METALLOTHIONEIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL NUCLEUS; CELL STRESS; CELL SURVIVAL; CELL VACUOLE; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; KIDNEY CELL; KIDNEY PROXIMAL TUBULE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; POLLUTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TOXICOKINETICS; UPREGULATION;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HEAT-SHOCK PROTEINS; HSP27 HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; KIDNEY TUBULES, PROXIMAL; LEAD; MERCURIC CHLORIDE; METALLOTHIONEIN; MITOCHONDRIA; MOLECULAR CHAPERONES; NECROSIS; NITRIC OXIDE; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; TIME FACTORS;

RATTUS;

EID: 70349213201     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.08.014     Document Type: Article

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