The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Wifling, David ^a   Bernhardt, Günther ^a   Dove, Stefan ^a   Buschauer, Armin ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; EXTRACELLULAR LOOP 2; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; HISTAMINE; HISTAMINE H4 RECEPTOR; LIGAND; THIOPERAMIDE; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; HISTAMINE RECEPTOR; HRH4 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HISTAMINE METABOLISM; LIGAND BINDING; MUTATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; BINDING SITE; HUMAN; METABOLISM; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

HEXAPODA; RATTUS;

BINDING SITES; HISTAMINE; HUMANS; LIGANDS; MODELS, MOLECULAR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84922193619     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117185     Document Type: Article

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