Multiple residues in the second extracellular loop are critical for M 3 muscarinic acetylcholine receptor activation

Journal of Biological Chemistry

Volumn 282, Issue 10, 2007, Pages 7385-7396

  Scarselli, Marco ^a   Li, Bo ^a   Kim, Soo Kyung ^a,b   Wess, Jürgen ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; BOVINE RHODOPSIN; STRUCTURAL HOMOLOGY; TRANSMEMBRANE RECEPTOR CORE;

AMINES; AMINO ACIDS; MUTAGENESIS; PROTEINS;

BIOCHEMISTRY;

AMINO ACID; ARGININE; BIOGENIC AMINE; CYSTEINE; GLUTAMINE; GLYCINE; ISOLEUCINE; LEUCINE; MUSCARINIC RECEPTOR; PHENYLALANINE; PROLINE; MUSCARINIC M3 RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; GENETICS; MAMMAL CELL; MUTAGENESIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; STRUCTURAL HOMOLOGY; YEAST; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR GENETICS; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION;

BOVINAE; MAMMALIA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; RECEPTOR, MUSCARINIC M3; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34147167536     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610394200     Document Type: Article

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