메뉴 건너뛰기




Volumn 47, Issue 2, 2015, Pages 303-315

Evaluation of 99mTc-ZIGF1R:4551-GGGC affibody molecule, a new probe for imaging of insulin-like growth factor type 1 receptor expression

Author keywords

99mTc; Affibody molecule; Biodistribution; IGF 1R; Peptide based chelator

Indexed keywords

RADIOPHARMACEUTICAL AGENT; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; Z SOMATOMEDIN C RECEPTOR 4551 GLYCYLGLYCYLGLYCYLCYSTEINE TC 99M; HYBRID PROTEIN; IGF1R PROTEIN, HUMAN; SOMATOMEDIN RECEPTOR; TECHNETIUM; TUMOR PROTEIN;

EID: 84922105067     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-014-1859-z     Document Type: Article
Times cited : (23)

References (48)
  • 1
    • 79952118497 scopus 로고    scopus 로고
    • Radionuclide molecular imaging using Affibody molecules
    • 1:CAS:528:DC%2BC3cXht1CmsrjI 20497119
    • Ahlgren S, Tolmachev V (2010) Radionuclide molecular imaging using Affibody molecules. Curr Pharm Biotechnol 11:581-589
    • (2010) Curr Pharm Biotechnol , vol.11 , pp. 581-589
    • Ahlgren, S.1    Tolmachev, V.2
  • 4
    • 77953872478 scopus 로고    scopus 로고
    • Kit formulation for 99mTc-labeling of recombinant anti-HER2 Affibody molecules with a C-terminally engineered cysteine
    • 1:CAS:528:DC%2BC3cXnvVOqu74%3D 20610158
    • Ahlgren S, Andersson K, Tolmachev V (2010) Kit formulation for 99mTc-labeling of recombinant anti-HER2 Affibody molecules with a C-terminally engineered cysteine. Nucl Med Biol 37:539-546
    • (2010) Nucl Med Biol , vol.37 , pp. 539-546
    • Ahlgren, S.1    Andersson, K.2    Tolmachev, V.3
  • 5
    • 59849091763 scopus 로고    scopus 로고
    • The insulin receptor substrate-1: A biomarker for cancer?
    • 1:CAS:528:DC%2BD1MXitFSgsLw%3D 18851963
    • Baserga R (2009) The insulin receptor substrate-1: a biomarker for cancer? Exp Cell Res 315:727-732
    • (2009) Exp Cell Res , vol.315 , pp. 727-732
    • Baserga, R.1
  • 6
    • 79551631839 scopus 로고    scopus 로고
    • Comparing the epidermal growth factor interaction with four different cell lines: Intriguing effects imply strong dependency of cellular context
    • Björkelund H, Gedda L, Andersson K (2011) Comparing the epidermal growth factor interaction with four different cell lines: intriguing effects imply strong dependency of cellular context. PLoS One 31(6):e16536
    • (2011) PLoS One , vol.31 , Issue.6 , pp. 16536
    • Björkelund, H.1    Gedda, L.2    Andersson, K.3
  • 7
    • 68849085354 scopus 로고    scopus 로고
    • Predictive biomarkers for targeting insulin-like growth factor-I (IGF-I) receptor
    • 1:CAS:528:DC%2BD1MXpvFCnur4%3D 19671737
    • Carden CP, Molife LR, de Bono JS (2009) Predictive biomarkers for targeting insulin-like growth factor-I (IGF-I) receptor. Mol Cancer Ther 8:2077-2078
    • (2009) Mol Cancer Ther , vol.8 , pp. 2077-2078
    • Carden, C.P.1    Molife, L.R.2    De Bono, J.S.3
  • 9
    • 34047198390 scopus 로고    scopus 로고
    • Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2
    • 1:CAS:528:DC%2BD2sXnvFCltb8%3D 17374994
    • Dearth RK, Cui X, Kim HJ, Hadsell DL, Lee AV (2007) Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2. Cell Cycle 6:705-713
    • (2007) Cell Cycle , vol.6 , pp. 705-713
    • Dearth, R.K.1    Cui, X.2    Kim, H.J.3    Hadsell, D.L.4    Lee, A.V.5
  • 12
    • 0031585866 scopus 로고    scopus 로고
    • Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells
    • 1:CAS:528:DyaK2sXhsVKktL4%3D 9056422
    • Guvakova MA, Surmacz E (1997) Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells. Exp Cell Res 231:149-162
    • (1997) Exp Cell Res , vol.231 , pp. 149-162
    • Guvakova, M.A.1    Surmacz, E.2
  • 13
    • 84878376748 scopus 로고    scopus 로고
    • The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer
    • 1:CAS:528:DC%2BC3sXns1Gjsb4%3D 23569026
    • Haisa M (2013) The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer. J Int Med Res 41:253-264
    • (2013) J Int Med Res , vol.41 , pp. 253-264
    • Haisa, M.1
  • 15
    • 0037092971 scopus 로고    scopus 로고
    • Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease
    • 1:CAS:528:DC%2BD38XjvFSmtLg%3D 12019176
    • Hellawell GO, Turner GD, Davies DR, Poulsom R, Brewster SF, Macaulay VM (2002) Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease. Cancer Res 62:2942-2950
    • (2002) Cancer Res , vol.62 , pp. 2942-2950
    • Hellawell, G.O.1    Turner, G.D.2    Davies, D.R.3    Poulsom, R.4    Brewster, S.F.5    Macaulay, V.M.6
  • 18
    • 79958148943 scopus 로고    scopus 로고
    • The use of a HEHEHE-purification tag improves biodistribution of Affibody molecules site-specifically labeled with 99mTc, 111In and 125I compared to a hexahistidine-tag
    • 21524142
    • Hofström C, Orlova A, Altai M, Wångsell F, Gräslund T, Tolmachev V (2011) The use of a HEHEHE-purification tag improves biodistribution of Affibody molecules site-specifically labeled with 99mTc, 111In and 125I compared to a hexahistidine-tag. J Med Chem 54:3817-3826
    • (2011) J Med Chem , vol.54 , pp. 3817-3826
    • Hofström, C.1    Orlova, A.2    Altai, M.3    Wångsell, F.4    Gräslund, T.5    Tolmachev, V.6
  • 20
    • 0000448982 scopus 로고
    • Prediction of protein antigenic determinants from amino acid sequences
    • 1:CAS:528:DyaL3MXksF2lu7s%3D 319665 6167991
    • Hopp TP, Woods KR (1981) Prediction of protein antigenic determinants from amino acid sequences. Proc Natl Acad Sci USA 78:3824-3828
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 3824-3828
    • Hopp, T.P.1    Woods, K.R.2
  • 21
    • 84868101162 scopus 로고    scopus 로고
    • Liver uptake of radiolabeled targeting proteins and peptides: Considerations for targeting peptide conjugate design
    • 1:CAS:528:DC%2BC38XhtV2mt7jI 22781499
    • Hosseinimehr SJ, Tolmachev V, Orlova A (2012) Liver uptake of radiolabeled targeting proteins and peptides: considerations for targeting peptide conjugate design. Drug Discov Today 17:1224-1232
    • (2012) Drug Discov Today , vol.17 , pp. 1224-1232
    • Hosseinimehr, S.J.1    Tolmachev, V.2    Orlova, A.3
  • 22
    • 84866486496 scopus 로고    scopus 로고
    • Targeting insulin-like growth factor in breast cancer therapeutics
    • 22424863
    • Karamouzis MV, Papavassiliou AG (2012) Targeting insulin-like growth factor in breast cancer therapeutics. Crit Rev Oncol Hematol 84:8-17
    • (2012) Crit Rev Oncol Hematol , vol.84 , pp. 8-17
    • Karamouzis, M.V.1    Papavassiliou, A.G.2
  • 23
    • 0034453098 scopus 로고    scopus 로고
    • The effects of insulin-like growth factors on tumorigenesis and neoplastic growth
    • 1:CAS:528:DC%2BD3cXlsF2gt7w%3D 10857553
    • Khandwala HM, McCutcheon IE, Flyvbjerg A, Friend KE (2000) The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev 21:215-244
    • (2000) Endocr Rev , vol.21 , pp. 215-244
    • Khandwala, H.M.1    McCutcheon, I.E.2    Flyvbjerg, A.3    Friend, K.E.4
  • 24
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • 1:CAS:528:DyaL38Xks1yjtro%3D 7108955
    • Kyte J, Doolittle RF (1982) A simple method for displaying the hydropathic character of a protein. J Mol Biol 157:105-132
    • (1982) J Mol Biol , vol.157 , pp. 105-132
    • Kyte, J.1    Doolittle, R.F.2
  • 25
    • 0038398622 scopus 로고    scopus 로고
    • The insulin-like growth factor system and cancer
    • 1:CAS:528:DC%2BD3sXktFWmsrk%3D 12767520
    • LeRoith D, Roberts CT Jr (2003) The insulin-like growth factor system and cancer. Cancer Lett 195:127-137
    • (2003) Cancer Lett , vol.195 , pp. 127-137
    • Leroith, D.1    Roberts, C.T.2
  • 26
    • 77954828431 scopus 로고    scopus 로고
    • Selection of affibody molecules to the ligand-binding site of the insulin-like growth factor-1 receptor
    • 1:CAS:528:DC%2BC3cXksVKqsbk%3D 20088825
    • Li J, Lundberg E, Vernet E, Larsson B, Höidén-Guthenberg I, Gräslund T (2010) Selection of affibody molecules to the ligand-binding site of the insulin-like growth factor-1 receptor. Biotechnol Appl Biochem 55:99-109
    • (2010) Biotechnol Appl Biochem , vol.55 , pp. 99-109
    • Li, J.1    Lundberg, E.2    Vernet, E.3    Larsson, B.4    Höidén-Guthenberg, I.5    Gräslund, T.6
  • 27
    • 84879055684 scopus 로고    scopus 로고
    • Co-inhibition of epidermal growth factor receptor and insulin-like growth factor receptor 1 enhances radiosensitivity in human breast cancer cells
    • 1:CAS:528:DC%2BC3sXht1WjsLrF 3697997 23777562
    • Li P, Veldwijk MR, Zhang Q, Li ZB, Xu WC, Fu S (2013) Co-inhibition of epidermal growth factor receptor and insulin-like growth factor receptor 1 enhances radiosensitivity in human breast cancer cells. BMC Cancer 13:297
    • (2013) BMC Cancer , vol.13 , pp. 297
    • Li, P.1    Veldwijk, M.R.2    Zhang, Q.3    Li, Z.B.4    Xu, W.C.5    Fu, S.6
  • 28
    • 84863581172 scopus 로고    scopus 로고
    • Evaluation of a HER2-targeting affibody molecule combining an N-terminal HEHEHE-tag with a GGGC chelator for 99mTc-labelling at the C terminus
    • 1:CAS:528:DC%2BC38XmsF2nur4%3D 22249974
    • Lindberg H, Hofström C, Altai M, Honorvar H, Wållberg H, Orlova A, Ståhl S, Gräslund T, Tolmachev V (2012) Evaluation of a HER2-targeting affibody molecule combining an N-terminal HEHEHE-tag with a GGGC chelator for 99mTc-labelling at the C terminus. Tumour Biol 33:641-651
    • (2012) Tumour Biol , vol.33 , pp. 641-651
    • Lindberg, H.1    Hofström, C.2    Altai, M.3    Honorvar, H.4    Wållberg, H.5    Orlova, A.6    Ståhl, S.7    Gräslund, T.8    Tolmachev, V.9
  • 29
    • 77953130101 scopus 로고    scopus 로고
    • Affibody molecules: Engineered proteins for therapeutic, diagnostic and biotechnological applications
    • 20388508
    • Löfblom J, Feldwisch J, Tolmachev V, Carlsson J, Ståhl S, Frejd FY (2010) Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications. FEBS Lett 584:2670-2680
    • (2010) FEBS Lett , vol.584 , pp. 2670-2680
    • Löfblom, J.1    Feldwisch, J.2    Tolmachev, V.3    Carlsson, J.4    Ståhl, S.5    Frejd, F.Y.6
  • 30
    • 43549101411 scopus 로고    scopus 로고
    • Alternative binding proteins: Affibody binding proteins developed from a small three-helix bundle scaffold
    • 1:CAS:528:DC%2BD1cXnt1CjsrY%3D 18435759
    • Nygren PA (2008) Alternative binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold. FEBS J 275:2668-2676
    • (2008) FEBS J , vol.275 , pp. 2668-2676
    • Nygren, P.A.1
  • 32
    • 0042889104 scopus 로고    scopus 로고
    • Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas
    • 1:CAS:528:DC%2BD3sXmslegu7w%3D 14506643
    • Ouban A, Muraca P, Yeatman T, Coppola D (2003) Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas. Hum Pathol 34(8):803-808
    • (2003) Hum Pathol , vol.34 , Issue.8 , pp. 803-808
    • Ouban, A.1    Muraca, P.2    Yeatman, T.3    Coppola, D.4
  • 33
    • 84855467975 scopus 로고    scopus 로고
    • The insulin receptor/insulin-like growth factor receptor family as a therapeutic target in oncology
    • 1:CAS:528:DC%2BC38XhvFWnug%3D%3D 22215905
    • Pollak M (2012) The insulin receptor/insulin-like growth factor receptor family as a therapeutic target in oncology. Clin Cancer Res 18:40-50
    • (2012) Clin Cancer Res , vol.18 , pp. 40-50
    • Pollak, M.1
  • 34
    • 3042781558 scopus 로고    scopus 로고
    • Insulin-like growth factors and neoplasia
    • 1:CAS:528:DC%2BD2cXlt1Oktro%3D 15229476
    • Pollak MN, Schernhammer ES, Hankinson SE (2004) Insulin-like growth factors and neoplasia. Nat Rev Cancer 4:505-518
    • (2004) Nat Rev Cancer , vol.4 , pp. 505-518
    • Pollak, M.N.1    Schernhammer, E.S.2    Hankinson, S.E.3
  • 35
    • 33846807433 scopus 로고    scopus 로고
    • Disrupting insulin-like growth factor signaling as a potential cancer therapy
    • 1:CAS:528:DC%2BD2sXmsVantg%3D%3D 17237261
    • Sachdev D, Yee D (2007) Disrupting insulin-like growth factor signaling as a potential cancer therapy. Mol Cancer Ther 6:1-12
    • (2007) Mol Cancer Ther , vol.6 , pp. 1-12
    • Sachdev, D.1    Yee, D.2
  • 36
    • 41949106937 scopus 로고    scopus 로고
    • An investigation of the ligand binding properties and negative cooperativity of soluble insulin-like growth factor receptors
    • 1:CAS:528:DC%2BD1cXit1Omsbw%3D 18056713
    • Surinya KH, Forbes BE, Occhiodoro F, Booker GW, Francis GL, Siddle K, Wallace JC, Cosgrove LJ (2008) An investigation of the ligand binding properties and negative cooperativity of soluble insulin-like growth factor receptors. J Biol Chem 283:5355-5363
    • (2008) J Biol Chem , vol.283 , pp. 5355-5363
    • Surinya, K.H.1    Forbes, B.E.2    Occhiodoro, F.3    Booker, G.W.4    Francis, G.L.5    Siddle, K.6    Wallace, J.C.7    Cosgrove, L.J.8
  • 38
    • 77957374838 scopus 로고    scopus 로고
    • Radiolabelled receptor-tyrosine-kinase targeting drugs for patient stratification and monitoring of therapy response: Prospects and pitfalls
    • 1:CAS:528:DC%2BC3cXht1ertLjI 20667780
    • Tolmachev V, Stone-Elander S, Orlova A (2010a) Radiolabelled receptor-tyrosine-kinase targeting drugs for patient stratification and monitoring of therapy response: prospects and pitfalls. Lancet Oncol 11:992-1000
    • (2010) Lancet Oncol , vol.11 , pp. 992-1000
    • Tolmachev, V.1    Stone-Elander, S.2    Orlova, A.3
  • 40
    • 84855410318 scopus 로고    scopus 로고
    • Imaging of insulin like growth factor type 1 receptor in prostate cancer xenografts using the affibody molecule 111In-DOTA-ZIGF1R:4551
    • 1:CAS:528:DC%2BC38XitFCjurs%3D 22173843
    • Tolmachev V, Malmberg J, Hofström C, Abrahmsén L, Bergman T, Sjöberg A, Sandström M, Gräslund T, Orlova A (2012a) Imaging of insulin like growth factor type 1 receptor in prostate cancer xenografts using the affibody molecule 111In-DOTA-ZIGF1R:4551. J Nucl Med 53:90-97
    • (2012) J Nucl Med , vol.53 , pp. 90-97
    • Tolmachev, V.1    Malmberg, J.2    Hofström, C.3    Abrahmsén, L.4    Bergman, T.5    Sjöberg, A.6    Sandström, M.7    Gräslund, T.8    Orlova, A.9
  • 41
    • 84861861669 scopus 로고    scopus 로고
    • Tumor targeting using affibody molecules: Interplay of affinity, target expression level, and binding site composition
    • 1:CAS:528:DC%2BC38XhtVyntL3L 22586147
    • Tolmachev V, Tran TA, Rosik D, Sjöberg A, Abrahmsén L, Orlova A (2012b) Tumor targeting using affibody molecules: interplay of affinity, target expression level, and binding site composition. J Nucl Med 53:953-960
    • (2012) J Nucl Med , vol.53 , pp. 953-960
    • Tolmachev, V.1    Tran, T.A.2    Rosik, D.3    Sjöberg, A.4    Abrahmsén, L.5    Orlova, A.6
  • 42
    • 84897943445 scopus 로고    scopus 로고
    • Imaging of platelet-derived growth factor receptor β expression in glioblastoma xenografts using affibody molecule 111In-DOTA-Z09591
    • 1:CAS:528:DC%2BC2cXltlaqtLo%3D 24408895
    • Tolmachev V, Varasteh Z, Honarvar H, Hosseinimehr SJ, Eriksson O, Jonasson P, Frejd FY, Abrahmsen L, Orlova A (2014) Imaging of platelet-derived growth factor receptor β expression in glioblastoma xenografts using affibody molecule 111In-DOTA-Z09591. J Nucl Med 55:294-300
    • (2014) J Nucl Med , vol.55 , pp. 294-300
    • Tolmachev, V.1    Varasteh, Z.2    Honarvar, H.3    Hosseinimehr, S.J.4    Eriksson, O.5    Jonasson, P.6    Frejd, F.Y.7    Abrahmsen, L.8    Orlova, A.9
  • 43
    • 33947644139 scopus 로고    scopus 로고
    • In vivo evaluation of cysteine-based chelators for attachment of 99mTc to tumor-targeting Affibody molecules
    • 1:CAS:528:DC%2BD2sXisVGmu7c%3D 17330952
    • Tran T, Engfeldt T, Orlova A, Widström C, Bruskin A, Tolmachev V, Karlström AE (2007) In vivo evaluation of cysteine-based chelators for attachment of 99mTc to tumor-targeting Affibody molecules. Bioconjug Chem 18:549-558
    • (2007) Bioconjug Chem , vol.18 , pp. 549-558
    • Tran, T.1    Engfeldt, T.2    Orlova, A.3    Widström, C.4    Bruskin, A.5    Tolmachev, V.6    Karlström, A.E.7
  • 44
    • 16944364325 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation
    • 1:CAS:528:DyaK2sXkvFKrurw%3D 9242428
    • Turner BC, Haffty BG, Narayanan L, Yuan J, Havre PA, Gumbs AA, Kaplan L, Burgaud JL, Carter D, Baserga R, Glazer PM (1997) Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. Cancer Res 57:3079-3083
    • (1997) Cancer Res , vol.57 , pp. 3079-3083
    • Turner, B.C.1    Haffty, B.G.2    Narayanan, L.3    Yuan, J.4    Havre, P.A.5    Gumbs, A.A.6    Kaplan, L.7    Burgaud, J.L.8    Carter, D.9    Baserga, R.10    Glazer, P.M.11
  • 46
    • 79952798198 scopus 로고    scopus 로고
    • Molecular design and optimization of 99mTc-labeled recombinant affibody molecules improves their biodistribution and imaging properties
    • 21321280
    • Wållberg H, Orlova A, Altai M, Hosseinimehr SJ, Widström C, Malmberg J, Ståhl S, Tolmachev V (2011) Molecular design and optimization of 99mTc-labeled recombinant affibody molecules improves their biodistribution and imaging properties. J Nucl Med 52:461-469
    • (2011) J Nucl Med , vol.52 , pp. 461-469
    • Wållberg, H.1    Orlova, A.2    Altai, M.3    Hosseinimehr, S.J.4    Widström, C.5    Malmberg, J.6    Ståhl, S.7    Tolmachev, V.8
  • 47
    • 68149103024 scopus 로고    scopus 로고
    • The insulin-like growth factor-I receptor as an oncogene
    • 1:CAS:528:DC%2BD1MXhtlCqtLjI 19485702
    • Werner H, Bruchim I (2009) The insulin-like growth factor-I receptor as an oncogene. Arch Physiol Biochem 115:58-71
    • (2009) Arch Physiol Biochem , vol.115 , pp. 58-71
    • Werner, H.1    Bruchim, I.2
  • 48
    • 2342583415 scopus 로고    scopus 로고
    • Kinetics of perrhenate uptake and comparative biodistribution of perrhenate, pertechnetate, and iodide by NaI symporter-expressing tissues in vivo
    • 1:CAS:528:DC%2BD2cXivVCju7k%3D 15001694
    • Zuckier LS, Dohan O, Li Y, Chang C, Carrasco N, Dadachova E (2004) Kinetics of perrhenate uptake and comparative biodistribution of perrhenate, pertechnetate, and iodide by NaI symporter-expressing tissues in vivo. J Nucl Med 45:500-507
    • (2004) J Nucl Med , vol.45 , pp. 500-507
    • Zuckier, L.S.1    Dohan, O.2    Li, Y.3    Chang, C.4    Carrasco, N.5    Dadachova, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.