Depletion of the type 1 IGF receptor delays repair of radiation-induced DNA double strand breaks

Radiotherapy and Oncology

Volumn 103, Issue 3, 2012, Pages 402-409

  Turney, Benjamin W ^a,b   Kerr, Martin ^a   Chitnis, Meenali M ^a,b   Lodhia, Kunal ^a   Wang, Yong ^a   Riedemann, Johann ^a   Rochester, Mark ^a   Protheroe, Andrew S ^b   Brewster, Simon F ^b   MacAulay, Valentine M ^a,b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

DNA double strand break; DNA repair; IGF; IGF 1R; Prostate cancer; Type 1 IGF receptor

Indexed keywords

SOMATOMEDIN C RECEPTOR;

ARTICLE; CANCER CELL; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IONIZING RADIATION; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEPLETION; RADIATION EXPOSURE; RADIOSENSITIZATION;

CELL CYCLE; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; ELECTROPHORESIS, GEL, PULSED-FIELD; HISTONES; HOMOLOGOUS RECOMBINATION; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; MALE; PROSTATIC NEOPLASMS; RADIATION DOSAGE; RADIATION TOLERANCE; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; RNA, SMALL INTERFERING;

EID: 84861822121     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2012.03.009     Document Type: Article

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