-
1
-
-
84866430997
-
Emerging role of neuronal exosomes in the central nervous system
-
Chivet, M., Hemming, F., Pernet-Gallay, K., Fraboulet, S., and Sadoul, R. (2012) Emerging role of neuronal exosomes in the central nervous system. Front. Physiol. 3, 145
-
(2012)
Front. Physiol.
, vol.3
, pp. 145
-
-
Chivet, M.1
Hemming, F.2
Pernet-Gallay, K.3
Fraboulet, S.4
Sadoul, R.5
-
2
-
-
27544470486
-
Snaring the function of α-synuclein
-
Bonini, N. M., and Giasson, B. I. (2005) Snaring the function of α-synuclein. Cell 123, 359-361
-
(2005)
Cell
, vol.123
, pp. 359-361
-
-
Bonini, N.M.1
Giasson, B.I.2
-
3
-
-
0034193399
-
Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
-
Murphy, D. D., Rueter, S. M., Trojanowski, J. Q., and Lee, V. M. (2000) Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J. neurosci. 20, 3214-3220
-
(2000)
J. Neurosci.
, vol.20
, pp. 3214-3220
-
-
Murphy, D.D.1
Rueter, S.M.2
Trojanowski, J.Q.3
Lee, V.M.4
-
4
-
-
84861563520
-
Direct observation of the interconversion of normal and toxic forms of α-synuclein
-
Cremades, N., Cohen, S. I., Deas, E., Abramov, A. Y., Chen, A. Y., Orte, A., Sandal, M., Clarke, R. W., Dunne, P., Aprile, F. A., Bertoncini, C. W., Wood, N. W., Knowles, T. P., Dobson, C. M., and Klenerman, D. (2012) Direct observation of the interconversion of normal and toxic forms of α-synuclein. Cell 149, 1048-1059
-
(2012)
Cell
, vol.149
, pp. 1048-1059
-
-
Cremades, N.1
Cohen, S.I.2
Deas, E.3
Abramov, A.Y.4
Chen, A.Y.5
Orte, A.6
Sandal, M.7
Clarke, R.W.8
Dunne, P.9
Aprile, F.A.10
Bertoncini, C.W.11
Wood, N.W.12
Knowles, T.P.13
Dobson, C.M.14
Klenerman, D.15
-
5
-
-
58149131277
-
Neurobiology and treatment of Parkinson's disease
-
Schapira, A. H. (2009) Neurobiology and treatment of Parkinson's disease. Trends Pharmacol. Sci. 30, 41-47
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 41-47
-
-
Schapira, A.H.1
-
6
-
-
0032929645
-
A data-driven approach to the study of heterogeneity in idiopathic Parkinson's disease: Identification of three distinct subtypes
-
Graham, J. M., and Sagar, H. J. (1999) A data-driven approach to the study of heterogeneity in idiopathic Parkinson's disease: identification of three distinct subtypes. Movement Disorders 14, 10-20
-
(1999)
Movement Disorders
, vol.14
, pp. 10-20
-
-
Graham, J.M.1
Sagar, H.J.2
-
7
-
-
79960842310
-
Neuropathology underlying clinical variability in patients with synucleinopathies
-
Halliday, G. M., Holton, J. L., Revesz, T., and Dickson, D. W. (2011) Neuropathology underlying clinical variability in patients with synucleinopathies. Acta Neuropathol. 122, 187-204
-
(2011)
Acta Neuropathol.
, vol.122
, pp. 187-204
-
-
Halliday, G.M.1
Holton, J.L.2
Revesz, T.3
Dickson, D.W.4
-
8
-
-
27644548054
-
α-Synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease
-
Halliday, G. M., Ophof, A., Broe, M., Jensen, P. H., Kettle, E., Fedorow, H., Cartwright, M. I., Griffiths, F. M., Shepherd, C. E., and Double, K. L. (2005) α-Synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease. Brain 128, 2654-2664
-
(2005)
Brain
, vol.128
, pp. 2654-2664
-
-
Halliday, G.M.1
Ophof, A.2
Broe, M.3
Jensen, P.H.4
Kettle, E.5
Fedorow, H.6
Cartwright, M.I.7
Griffiths, F.M.8
Shepherd, C.E.9
Double, K.L.10
-
9
-
-
23644461006
-
Lewy bodies in Parkinson's disease: Protectors or perpetrators?
-
Harrower, T. P., Michell, A. W., and Barker, R. A. (2005) Lewy bodies in Parkinson's disease: protectors or perpetrators? Exp. Neurol. 195, 1-6
-
(2005)
Exp. Neurol.
, vol.195
, pp. 1-6
-
-
Harrower, T.P.1
Michell, A.W.2
Barker, R.A.3
-
10
-
-
34648819365
-
The Lewy body in Parkinson's disease: Molecules implicated in the formation and degradation of α-synuclein aggregates
-
Wakabayashi, K., Tanji, K., Mori, F., and Takahashi, H. (2007) The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of α-synuclein aggregates. Neuropathology 27, 494-506
-
(2007)
Neuropathology
, vol.27
, pp. 494-506
-
-
Wakabayashi, K.1
Tanji, K.2
Mori, F.3
Takahashi, H.4
-
11
-
-
79952742454
-
In vivo demonstration that α-synuclein oligomers are toxic
-
Winner, B., Jappelli, R., Maji, S. K., Desplats, P. A., Boyer, L., Aigner, S., Hetzer, C., Loher, T., Vilar, M., Campioni, S., Tzitzilonis, C., Soragni, A., Jessberger, S., Mira, H., Consiglio, A., Pham, E., Masliah, E., Gage, F. H., and Riek, R. (2011) In vivo demonstration that α-synuclein oligomers are toxic. Proc. Natl. Sci. Acad. U.S.A. 108, 4194-4199
-
(2011)
Proc. Natl. Sci. Acad. U.S.A.
, vol.108
, pp. 4194-4199
-
-
Winner, B.1
Jappelli, R.2
Maji, S.K.3
Desplats, P.A.4
Boyer, L.5
Aigner, S.6
Hetzer, C.7
Loher, T.8
Vilar, M.9
Campioni, S.10
Tzitzilonis, C.11
Soragni, A.12
Jessberger, S.13
Mira, H.14
Consiglio, A.15
Pham, E.16
Masliah, E.17
Gage, F.H.18
Riek, R.19
-
12
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini, M., Giannoni, E., Chiti, F., Baroni, F., Formigli, L., Zurdo, J., Taddei, N., Ramponi, G., Dobson, C. M., and Stefani, M. (2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416, 507-511
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
13
-
-
84871414210
-
The many faces of α-synuclein: From structure and toxicity to therapeutic target
-
Lashuel, H. A., Overk, C. R., Oueslati, A., and Masliah, E. (2013) The many faces of α-synuclein: from structure and toxicity to therapeutic target. Nat. Rev. Neurosci. 14, 38-48
-
(2013)
Nat. Rev. Neurosci.
, vol.14
, pp. 38-48
-
-
Lashuel, H.A.1
Overk, C.R.2
Oueslati, A.3
Masliah, E.4
-
14
-
-
0038341134
-
A broken α-helix in folded α-synuclein
-
Chandra, S., Chen, X., Rizo, J., Jahn, R., and Südhof, T. C. (2003) A broken α-helix in folded α-synuclein. J. Biol. Chem. 278, 15313-15318
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15313-15318
-
-
Chandra, S.1
Chen, X.2
Rizo, J.3
Jahn, R.4
Südhof, T.C.5
-
15
-
-
0035815115
-
Conformational properties of α-synuclein in its free and lipid-associated states
-
Eliezer, D., Kutluay, E., Bussell, R., Jr., and Browne, G. (2001) Conformational properties of α-synuclein in its free and lipid-associated states. J. Mol. Biol. 307, 1061-1073
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 1061-1073
-
-
Eliezer, D.1
Kutluay, E.2
Bussell, R.3
Browne, G.4
-
16
-
-
0038054286
-
A structural and functional role for 11-mer repeats in α-synuclein and other exchangeable lipid binding proteins
-
Bussell, R., Jr., and Eliezer, D. (2003) A structural and functional role for 11-mer repeats in α-synuclein and other exchangeable lipid binding proteins. J. Mol. Biol. 329, 763-778
-
(2003)
J. Mol. Biol.
, vol.329
, pp. 763-778
-
-
Bussell, R.1
Eliezer, D.2
-
17
-
-
79551498070
-
Direct evidence of coexisting horseshoe and extended helix conformations of membrane-bound α-synuclein
-
Robotta, M., Braun, P., van Rooijen, B., Subramaniam, V., Huber, M., and Drescher, M. (2011) Direct evidence of coexisting horseshoe and extended helix conformations of membrane-bound α-synuclein. Chem. Phys. Chem. 12, 267-269
-
(2011)
Chem. Phys. Chem.
, vol.12
, pp. 267-269
-
-
Robotta, M.1
Braun, P.2
Van Rooijen, B.3
Subramaniam, V.4
Huber, M.5
Drescher, M.6
-
18
-
-
34548620297
-
Neuropathology, biochemistry, and biophysics of α-synuclein aggregation
-
Uversky, V. N. (2007) Neuropathology, biochemistry, and biophysics of α-synuclein aggregation. J. Neurochem. 103, 17-37
-
(2007)
J. Neurochem.
, vol.103
, pp. 17-37
-
-
Uversky, V.N.1
-
19
-
-
4644290985
-
α-Synuclein locus duplication as a cause of familial Parkinson's disease
-
Chartier-Harlin, M. C., Kachergus, J., Roumier, C., Mouroux, V., Douay, X., Lincoln, S., Levecque, C., Larvor, L., Andrieux, J., Hulihan, M., Waucquier, N., Defebvre, L., Amouyel, P., Farrer, M., and Destée, A. (2004) α-Synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 364, 1167-1169
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hulihan, M.10
Waucquier, N.11
Defebvre, L.12
Amouyel, P.13
Farrer, M.14
Destée, A.15
-
20
-
-
0031990490
-
Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease
-
Krüger, R., Kuhn, W., Müller, T., Woitalla, D., Graeber, M., Kösel, S., Przuntek, H., Epplen, J. T., Schöls, L., and Riess, O. (1998) Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nat. Genet. 18, 106-108
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Krüger, R.1
Kuhn, W.2
Müller, T.3
Woitalla, D.4
Graeber, M.5
Kösel, S.6
Przuntek, H.7
Epplen, J.T.8
Schöls, L.9
Riess, O.10
-
21
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E. S., Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnson, W. G., Lazzarini, A. M., Duvoisin, R. C., Di Iorio, G., Golbe, L. I., and Nussbaum, R. L. (1997) Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
22
-
-
0242300619
-
α-Synuclein locus triplication causes Parkinson's disease
-
Singleton, A. B., Farrer, M., Johnson, J., Singleton, A., Hague, S., Kachergus, J., Hulihan, M., Peuralinna, T., Dutra, A., Nussbaum, R., Lincoln, S., Crawley, A., Hanson, M., Maraganore, D., Adler, C., Cookson, M. R., Muenter, M., Baptista, M., Miller, D., Blancato, J., Hardy, J., and Gwinn-Hardy, K. (2003) α-Synuclein locus triplication causes Parkinson's disease. Science 302, 841
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
23
-
-
10744230149
-
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
-
Zarranz, J. J., Alegre, J., Gómez-Esteban, J. C., Lezcano, E., Ros, R., Ampuero, I., Vidal, L., Hoenicka, J., Rodriguez, O., Atarés, B., Llorens, V., Gomez Tortosa, E., del Ser, T., Muñoz, D. G., and de Yebenes, J. G. (2004) The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia. Ann. Neurol. 55, 164-173
-
(2004)
Ann. Neurol.
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gómez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atarés, B.10
Llorens, V.11
Gomez Tortosa, E.12
Del Ser, T.13
Muñoz, D.G.14
De Yebenes, J.G.15
-
24
-
-
77957939093
-
Are synucleinopathies prion-like disorders?
-
Angot, E., Steiner, J. A., Hansen, C., Li, J. Y., and Brundin, P. (2010) Are synucleinopathies prion-like disorders? Lancet Neurol. 9, 1128-1138
-
(2010)
Lancet Neurol.
, vol.9
, pp. 1128-1138
-
-
Angot, E.1
Steiner, J.A.2
Hansen, C.3
Li, J.Y.4
Brundin, P.5
-
25
-
-
84874594129
-
What's to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease?
-
Dunning, C. J., George, S., and Brundin, P. (2013) What's to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease? Prion 7, 92-97
-
(2013)
Prion
, vol.7
, pp. 92-97
-
-
Dunning, C.J.1
George, S.2
Brundin, P.3
-
26
-
-
84903714886
-
Resistance of naturally secreted α-synuclein to proteolysis
-
Ximerakis, M., Pampalakis, G., Roumeliotis, T. I., Sykioti, V. S., Garbis, S. D., Stefanis, L., Sotiropoulou, G., and Vekrellis, K. (2014) Resistance of naturally secreted α-synuclein to proteolysis. FASEB J. 28, 3146-3158
-
(2014)
FASEB J.
, vol.28
, pp. 3146-3158
-
-
Ximerakis, M.1
Pampalakis, G.2
Roumeliotis, T.I.3
Sykioti, V.S.4
Garbis, S.D.5
Stefanis, L.6
Sotiropoulou, G.7
Vekrellis, K.8
-
27
-
-
77952648551
-
Cell-produced α-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival
-
Emmanouilidou, E., Melachroinou, K., Roumeliotis, T., Garbis, S. D., Ntzouni, M., Margaritis, L. H., Stefanis, L., and Vekrellis, K. (2010) Cell-produced α-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival. J. Neurosci. 30, 6838-6851
-
(2010)
J. Neurosci.
, vol.30
, pp. 6838-6851
-
-
Emmanouilidou, E.1
Melachroinou, K.2
Roumeliotis, T.3
Garbis, S.D.4
Ntzouni, M.5
Margaritis, L.H.6
Stefanis, L.7
Vekrellis, K.8
-
28
-
-
84866426167
-
Exosomes: Vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?
-
Bellingham, S. A., Guo, B. B., Coleman, B. M., and Hill, A. F. (2012) Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front. Physiol. 3, 124
-
(2012)
Front. Physiol.
, vol.3
, pp. 124
-
-
Bellingham, S.A.1
Guo, B.B.2
Coleman, B.M.3
Hill, A.F.4
-
29
-
-
84860686110
-
Can Parkinson's disease pathology be propagated from one neuron to another?
-
Dunning, C. J., Reyes, J. F., Steiner, J. A., and Brundin, P. (2012) Can Parkinson's disease pathology be propagated from one neuron to another? Prog. Neurobiol. 97, 205-219
-
(2012)
Prog. Neurobiol.
, vol.97
, pp. 205-219
-
-
Dunning, C.J.1
Reyes, J.F.2
Steiner, J.A.3
Brundin, P.4
-
30
-
-
84880135337
-
Exosomes of BV-2 cells induced by α-synuclein: Important mediator of neurodegeneration in PD
-
Chang, C., Lang, H., Geng, N., Wang, J., Li, N., and Wang, X. (2013) Exosomes of BV-2 cells induced by α-synuclein: important mediator of neurodegeneration in PD. Neurosci. Lett. 548, 190-195
-
(2013)
Neurosci. Lett.
, vol.548
, pp. 190-195
-
-
Chang, C.1
Lang, H.2
Geng, N.3
Wang, J.4
Li, N.5
Wang, X.6
-
31
-
-
84873173557
-
Exosomes as a novel way of interneuronal communication
-
Chivet, M., Javalet, C., Hemming, F., Pernet-Gallay, K., Laulagnier, K., Fraboulet, S., and Sadoul, R. (2013) Exosomes as a novel way of interneuronal communication. Biochem. Soc. Trans. 41, 241-244
-
(2013)
Biochem. Soc. Trans.
, vol.41
, pp. 241-244
-
-
Chivet, M.1
Javalet, C.2
Hemming, F.3
Pernet-Gallay, K.4
Laulagnier, K.5
Fraboulet, S.6
Sadoul, R.7
-
32
-
-
84865307818
-
Exosomal cell-to-cell transmission of α synuclein oligomers
-
Danzer, K. M., Kranich, L. R., Ruf, W. P., Cagsal-Getkin, O., Winslow, A. R., Zhu, L., Vanderburg, C. R., and McLean, P. J. (2012) Exosomal cell-to-cell transmission of α synuclein oligomers. Mol. Neurodegener. 7, 42
-
(2012)
Mol. Neurodegener.
, vol.7
, pp. 42
-
-
Danzer, K.M.1
Kranich, L.R.2
Ruf, W.P.3
Cagsal-Getkin, O.4
Winslow, A.R.5
Zhu, L.6
Vanderburg, C.R.7
McLean, P.J.8
-
33
-
-
79954631518
-
Lysosomal dysfunction increases exosome-mediated α-synuclein release and transmission
-
Alvarez-Erviti, L., Seow, Y., Schapira, A. H., Gardiner, C., Sargent, I. L., Wood, M. J., and Cooper, J. M. (2011) Lysosomal dysfunction increases exosome-mediated α-synuclein release and transmission. Neurobiol. Dis. 42, 360-367
-
(2011)
Neurobiol. Dis.
, vol.42
, pp. 360-367
-
-
Alvarez-Erviti, L.1
Seow, Y.2
Schapira, A.H.3
Gardiner, C.4
Sargent, I.L.5
Wood, M.J.6
Cooper, J.M.7
-
34
-
-
84870769168
-
Environmental toxins trigger PD-like progression via increased α-synuclein release from enteric neurons in mice
-
Pan-Montojo, F., Schwarz, M., Winkler, C., Arnhold, M., O'Sullivan, G. A., Pal, A., Said, J., Marsico, G., Verbavatz, J. M., Rodrigo-Angulo, M., Gille, G., Funk, R. H., and Reichmann, H. (2012) Environmental toxins trigger PD-like progression via increased α-synuclein release from enteric neurons in mice. Sci. Rep. 2, 898
-
(2012)
Sci. Rep.
, vol.2
, pp. 898
-
-
Pan-Montojo, F.1
Schwarz, M.2
Winkler, C.3
Arnhold, M.4
O'Sullivan, G.A.5
Pal, A.6
Said, J.7
Marsico, G.8
Verbavatz, J.M.9
Rodrigo-Angulo, M.10
Gille, G.11
Funk, R.H.12
Reichmann, H.13
-
35
-
-
84901660540
-
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
-
Buell, A. K., Galvagnion, C., Gaspar, R., Sparr, E., Vendruscolo, M., Knowles, T. P., Linse, S., and Dobson, C. M. (2014) Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation. Proc. Natl. Acad. Sci. U.S.A. 111, 7671-7676
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 7671-7676
-
-
Buell, A.K.1
Galvagnion, C.2
Gaspar, R.3
Sparr, E.4
Vendruscolo, M.5
Knowles, T.P.6
Linse, S.7
Dobson, C.M.8
-
36
-
-
84858268438
-
Membrane interaction of α-synuclein in different aggregation states
-
Grey, M., Linse, S., Nilsson, H., Brundin, P., Sparr E. (2011) Membrane interaction of α-synuclein in different aggregation states. J. Parkinsons Dis. 1, 359-371
-
(2011)
J. Parkinsons Dis.
, vol.1
, pp. 359-371
-
-
Grey, M.1
Linse, S.2
Nilsson, H.3
Brundin, P.4
Sparr, E.5
-
37
-
-
79551519276
-
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
-
Hansen, C., Angot, E., Bergström, A. L., Steiner, J. A., Pieri, L., Paul, G., Outeiro, T. F., Melki, R., Kallunki, P., Fog, K., Li, J. Y., and Brundin, P. (2011) α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J. Clin. Invest. 121, 715-725
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 715-725
-
-
Hansen, C.1
Angot, E.2
Bergström, A.L.3
Steiner, J.A.4
Pieri, L.5
Paul, G.6
Outeiro, T.F.7
Melki, R.8
Kallunki, P.9
Fog, K.10
Li, J.Y.11
Brundin, P.12
-
38
-
-
43249109372
-
Isolation and characterization of exosomes from cell culture supernatants and biological fluids
-
2006 Chapter 3, Unit 3.22
-
Théry, C., Amigorena, S., Raposo, G., and Clayton, A. (2006) Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr. Protoc. Cell Biol. 2006 Chapter 3, Unit 3.22
-
(2006)
Curr. Protoc. Cell Biol.
-
-
Théry, C.1
Amigorena, S.2
Raposo, G.3
Clayton, A.4
-
39
-
-
80051855646
-
Improved immunodetection of endogenous α-synuclein
-
Lee, B. R., and Kamitani, T. (2011) Improved immunodetection of endogenous α-synuclein. PLoS ONE 6, e23939
-
(2011)
PLoS ONE
, vol.6
, pp. e23939
-
-
Lee, B.R.1
Kamitani, T.2
-
40
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh, E. G., and Dyer, W. J. (1959) A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917
-
(1959)
Can. J. Biochem. Physiol.
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
41
-
-
84879052241
-
Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion
-
Ejlerskov, P., Rasmussen, I., Nielsen, T. T., Bergström, A. L., Tohyama, Y., Jensen, P. H., and Vilhardt, F. (2013) Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion. J. Biol. Chem. 288, 17313-17335
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 17313-17335
-
-
Ejlerskov, P.1
Rasmussen, I.2
Nielsen, T.T.3
Bergström, A.L.4
Tohyama, Y.5
Jensen, P.H.6
Vilhardt, F.7
-
42
-
-
79960096964
-
Exosomes: Secreted vesicles and intercellular communications
-
Théry, C. (2011) Exosomes: secreted vesicles and intercellular communications. F1000 Biol. Rep. 3, 15
-
(2011)
F1000 Biol. Rep.
, vol.3
, pp. 15
-
-
Théry, C.1
-
43
-
-
0037297655
-
Dielectric properties of blood: An investigation of haematocrit dependence
-
Jaspard, F., Nadi, M., and Rouane, A. (2003) Dielectric properties of blood: an investigation of haematocrit dependence. Physiol. Meas. 24, 137-147
-
(2003)
Physiol. Meas.
, vol.24
, pp. 137-147
-
-
Jaspard, F.1
Nadi, M.2
Rouane, A.3
-
44
-
-
0034713072
-
Structural biology. Proton-powered turbine of a plant motor
-
Seelert, H., Poetsch, A., Dencher, N. A., Engel, A., Stahlberg, H., and Müller, D. J. (2000) Structural biology. Proton-powered turbine of a plant motor. Nature 405, 418-419
-
(2000)
Nature
, vol.405
, pp. 418-419
-
-
Seelert, H.1
Poetsch, A.2
Dencher, N.A.3
Engel, A.4
Stahlberg, H.5
Müller, D.J.6
-
45
-
-
84886057818
-
Adsorption of α-synuclein to supported lipid bilayers: Positioning and role of electrostatics
-
Hellstrand, E., Grey, M., Ainalem, M. L., Ankner, J., Forsyth, V. T., Fragneto, G., Haertlein, M., Dauvergne, M. T., Nilsson, H., Brundin, P., Linse, S., Nylander, T., and Sparr, E. (2013) Adsorption of α-synuclein to supported lipid bilayers: positioning and role of electrostatics. ACS Chem. Neurosci. 4, 1339-1351
-
(2013)
ACS Chem. Neurosci.
, vol.4
, pp. 1339-1351
-
-
Hellstrand, E.1
Grey, M.2
Ainalem, M.L.3
Ankner, J.4
Forsyth, V.T.5
Fragneto, G.6
Haertlein, M.7
Dauvergne, M.T.8
Nilsson, H.9
Brundin, P.10
Linse, S.11
Nylander, T.12
Sparr, E.13
-
46
-
-
80052398365
-
α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
-
Bartels, T., Choi, J. G., and Selkoe, D. J. (2011) α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation. Nature 477, 107-110
-
(2011)
Nature
, vol.477
, pp. 107-110
-
-
Bartels, T.1
Choi, J.G.2
Selkoe, D.J.3
-
47
-
-
84859577559
-
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer
-
Fauvet, B., Mbefo, M. K., Fares, M. B., Desobry, C., Michael, S., Ardah, M. T., Tsika, E., Coune, P., Prudent, M., Lion, N., Eliezer, D., Moore, D. J., Schneider, B., Aebischer, P., El-Agnaf, O. M., Masliah, E., and Lashuel, H. A. (2012) α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer. J. Biol. Chem. 287, 15345-15364
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 15345-15364
-
-
Fauvet, B.1
Mbefo, M.K.2
Fares, M.B.3
Desobry, C.4
Michael, S.5
Ardah, M.T.6
Tsika, E.7
Coune, P.8
Prudent, M.9
Lion, N.10
Eliezer, D.11
Moore, D.J.12
Schneider, B.13
Aebischer, P.14
El-Agnaf, O.M.15
Masliah, E.16
Lashuel, H.A.17
-
48
-
-
77950689601
-
Strategies to increase the reproducibility of protein fibrillization in plate reader assays
-
Giehm, L., and Otzen, D. E. (2010) Strategies to increase the reproducibility of protein fibrillization in plate reader assays. Anal. Biochem. 400, 270-281
-
(2010)
Anal. Biochem.
, vol.400
, pp. 270-281
-
-
Giehm, L.1
Otzen, D.E.2
-
49
-
-
84875553835
-
On-surface aggregation of α-synuclein at nanomolar concentrations results in two distinct growth mechanisms
-
Rabe, M., Soragni, A., Reynolds, N. P., Verdes, D., Liverani, E., Riek, R., and Seeger, S. (2013) On-surface aggregation of α-synuclein at nanomolar concentrations results in two distinct growth mechanisms. ACS Chem. Neurosci. 4, 408-417
-
(2013)
ACS Chem. Neurosci.
, vol.4
, pp. 408-417
-
-
Rabe, M.1
Soragni, A.2
Reynolds, N.P.3
Verdes, D.4
Liverani, E.5
Riek, R.6
Seeger, S.7
-
50
-
-
77952320068
-
Molecular mechanism of thioflavin-T binding to amyloid fibrils
-
Biancalana, M., and Koide, S. (2010) Molecular mechanism of thioflavin-T binding to amyloid fibrils. Biochim. Biophys. Acta 1804, 1405-1412
-
(2010)
Biochim. Biophys. Acta
, vol.1804
, pp. 1405-1412
-
-
Biancalana, M.1
Koide, S.2
-
51
-
-
77951676986
-
Amyloid β-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process
-
Hellstrand, E., Boland, B., Walsh, D. M., and Linse, S. (2010) Amyloid β-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process. ACS Chem. Neurosci. 1, 13-18
-
(2010)
ACS Chem. Neurosci.
, vol.1
, pp. 13-18
-
-
Hellstrand, E.1
Boland, B.2
Walsh, D.M.3
Linse, S.4
-
52
-
-
84878994873
-
Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism
-
Cohen, S. I., Linse, S., Luheshi, L. M., Hellstrand, E., White, D. A., Rajah, L., Otzen, D. E., Vendruscolo, M., Dobson, C. M., and Knowles, T. P. (2013) Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism. Proc. Natl. Acad. Sci. U.S.A. 110, 9758-9763
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 9758-9763
-
-
Cohen, S.I.1
Linse, S.2
Luheshi, L.M.3
Hellstrand, E.4
White, D.A.5
Rajah, L.6
Otzen, D.E.7
Vendruscolo, M.8
Dobson, C.M.9
Knowles, T.P.10
-
53
-
-
84884169039
-
Ionization constants pKa of cardiolipin
-
Olofsson, G., and Sparr, E. (2013) Ionization constants pKa of cardiolipin. PLoS ONE 8, e73040
-
(2013)
PLoS ONE
, vol.8
, pp. e73040
-
-
Olofsson, G.1
Sparr, E.2
-
54
-
-
0014779155
-
Two-dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots
-
Rouser, G., Fkeischer, S., and Yamamoto, A. (1970) Two-dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids 5, 494-496
-
(1970)
Lipids
, vol.5
, pp. 494-496
-
-
Rouser, G.1
Fkeischer, S.2
Yamamoto, A.3
-
55
-
-
84885395711
-
Membrane lipid co-aggregation with α-synuclein fibrils
-
Hellstrand, E., Nowacka, A., Topgaard, D., Linse, S., and Sparr, E. (2013) Membrane lipid co-aggregation with α-synuclein fibrils. PLoS ONE 8, e77235
-
(2013)
PLoS ONE
, vol.8
, pp. e77235
-
-
Hellstrand, E.1
Nowacka, A.2
Topgaard, D.3
Linse, S.4
Sparr, E.5
-
56
-
-
33646446451
-
Structure of fully hydrated fluid phase lipid bilayers with monounsaturated chains
-
Kucerka, N., Tristram-Nagle, S., and Nagle, J. F. (2005) Structure of fully hydrated fluid phase lipid bilayers with monounsaturated chains. J. Membr. Biol. 208, 193-202
-
(2005)
J. Membr. Biol.
, vol.208
, pp. 193-202
-
-
Kucerka, N.1
Tristram-Nagle, S.2
Nagle, J.F.3
-
57
-
-
33847022701
-
GM1 specifically interacts with α-synuclein and inhibits fibrillation
-
Martinez, Z., Zhu, M., Han, S., and Fink, A. L. (2007) GM1 specifically interacts with α-synuclein and inhibits fibrillation. Biochemistry 46, 1868-1877
-
(2007)
Biochemistry
, vol.46
, pp. 1868-1877
-
-
Martinez, Z.1
Zhu, M.2
Han, S.3
Fink, A.L.4
-
58
-
-
0035815664
-
Evidence for a partially folded intermediate in α-synuclein fibril formation
-
Uversky, V. N., Li, J., and Fink, A. L. (2001) Evidence for a partially folded intermediate in α-synuclein fibril formation. J. Biol. Chem. 276, 10737-10744
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10737-10744
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
59
-
-
64849109238
-
α-Synuclein binds large unilamellar vesicles as an extended helix
-
Trexler, A. J., and Rhoades, E. (2009) α-Synuclein binds large unilamellar vesicles as an extended helix. Biochemistry 48, 2304-2306
-
(2009)
Biochemistry
, vol.48
, pp. 2304-2306
-
-
Trexler, A.J.1
Rhoades, E.2
-
60
-
-
77951681963
-
Dual effect of amino modified polystyrene nanoparticles on amyloid β protein fibrillation
-
Cabaleiro-Lago, C., Quinlan-Pluck, F., Lynch, I., Dawson, K. A., and Linse, S. (2010) Dual effect of amino modified polystyrene nanoparticles on amyloid β protein fibrillation. ACS Chem. Neurosci. 1, 279-287
-
(2010)
ACS Chem. Neurosci.
, vol.1
, pp. 279-287
-
-
Cabaleiro-Lago, C.1
Quinlan-Pluck, F.2
Lynch, I.3
Dawson, K.A.4
Linse, S.5
-
61
-
-
44049099669
-
Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi, L., Raghavendran, V., Prabhu, B. M., Avadhani, N. G., and Anandatheerthavarada, H. K. (2008) Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J. Biol. Chem. 283, 9089-9100
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
62
-
-
78651415502
-
Ion flux and the function of endosomes and lysosomes: PH is just the start
-
Scott, C. C., and Gruenberg, J. (2011) Ion flux and the function of endosomes and lysosomes: pH is just the start. BioEssays 33, 103-110
-
(2011)
BioEssays
, vol.33
, pp. 103-110
-
-
Scott, C.C.1
Gruenberg, J.2
-
63
-
-
44749085250
-
Mitochondrial translocation of α-synuclein is promoted by intracellular acidification
-
Cole, N. B., Dieuliis, D., Leo, P., Mitchell, D. C., and Nussbaum, R. L. (2008) Mitochondrial translocation of α-synuclein is promoted by intracellular acidification. Exp. Cell Res. 314, 2076-2089
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 2076-2089
-
-
Cole, N.B.1
Dieuliis, D.2
Leo, P.3
Mitchell, D.C.4
Nussbaum, R.L.5
-
64
-
-
84879046970
-
Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid raft-mediated endocytosis negatively regulated by caveolin-1
-
Svensson, K. J., Christianson, H. C., Wittrup, A., Bourseau-Guilmain, E., Lindqvist, E., Svensson, L. M., Mörgelin, M., and Belting, M. (2013) Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid raft-mediated endocytosis negatively regulated by caveolin-1. J. Biol. Chem. 288, 17713-17724
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 17713-17724
-
-
Svensson, K.J.1
Christianson, H.C.2
Wittrup, A.3
Bourseau-Guilmain, E.4
Lindqvist, E.5
Svensson, L.M.6
Mörgelin, M.7
Belting, M.8
-
65
-
-
77958455514
-
Effects of curvature and composition on α-synuclein binding to lipid vesicles
-
Middleton, E. R., and Rhoades, E. (2010) Effects of curvature and composition on α-synuclein binding to lipid vesicles. Biophys. J. 99, 2279-2288
-
(2010)
Biophys. J.
, vol.99
, pp. 2279-2288
-
-
Middleton, E.R.1
Rhoades, E.2
-
66
-
-
79957974579
-
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein α-synuclein
-
Nakamura, K., Nemani, V. M., Azarbal, F., Skibinski, G., Levy, J. M., Egami, K., Munishkina, L., Zhang, J., Gardner, B., Wakabayashi, J., Sesaki, H., Cheng, Y., Finkbeiner, S., Nussbaum, R. L., Masliah, E., and Edwards, R. H. (2011) Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein α-synuclein. J. Biol. Chem. 286, 20710-20726
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 20710-20726
-
-
Nakamura, K.1
Nemani, V.M.2
Azarbal, F.3
Skibinski, G.4
Levy, J.M.5
Egami, K.6
Munishkina, L.7
Zhang, J.8
Gardner, B.9
Wakabayashi, J.10
Sesaki, H.11
Cheng, Y.12
Finkbeiner, S.13
Nussbaum, R.L.14
Masliah, E.15
Edwards, R.H.16
-
67
-
-
37549068169
-
α-Synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains
-
Stöckl, M., Fischer, P., Wanker, E., and Herrmann, A. (2008) α-Synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains. J. Mol. Biol. 375, 1394-1404
-
(2008)
J. Mol. Biol.
, vol.375
, pp. 1394-1404
-
-
Stöckl, M.1
Fischer, P.2
Wanker, E.3
Herrmann, A.4
-
68
-
-
4444309565
-
The complex life of simple sphingolipids
-
Futerman, A. H., and Hannun, Y. A. (2004) The complex life of simple sphingolipids. EMBO Rep. 5, 777-782
-
(2004)
EMBO Rep.
, vol.5
, pp. 777-782
-
-
Futerman, A.H.1
Hannun, Y.A.2
-
69
-
-
84880168276
-
Binding and aggregation mechanism of amyloid β-peptides onto the GM1 gangli-oside- containing lipid membrane
-
Hoshino, T., Mahmood, M. I., Mori, K., and Matsuzaki, K. (2013) Binding and aggregation mechanism of amyloid β-peptides onto the GM1 gangli-oside- containing lipid membrane. J. Phys. Chem. B 117, 8085-8094
-
(2013)
J. Phys. Chem. B
, vol.117
, pp. 8085-8094
-
-
Hoshino, T.1
Mahmood, M.I.2
Mori, K.3
Matsuzaki, K.4
-
70
-
-
79952313543
-
Lipid matrix plays a role in Aβ fibril kinetics and morphology
-
Sani, M. A., Gehman, J. D., and Separovic, F. (2011) Lipid matrix plays a role in Aβ fibril kinetics and morphology. FEBS Lett. 585, 749-754
-
(2011)
FEBS Lett.
, vol.585
, pp. 749-754
-
-
Sani, M.A.1
Gehman, J.D.2
Separovic, F.3
-
71
-
-
51249115821
-
Formation of toxic Aβ (1-40) fibrils on GM1 ganglioside-containing membranes mimicking lipid rafts: Polymorphisms in Aβ (1-40) fibrils
-
Okada, T., Ikeda, K., Wakabayashi, M., Ogawa, M., and Matsuzaki, K. (2008) Formation of toxic Aβ (1-40) fibrils on GM1 ganglioside-containing membranes mimicking lipid rafts: polymorphisms in Aβ (1-40) fibrils. J. Mol. Biol. 382, 1066-1074
-
(2008)
J. Mol. Biol.
, vol.382
, pp. 1066-1074
-
-
Okada, T.1
Ikeda, K.2
Wakabayashi, M.3
Ogawa, M.4
Matsuzaki, K.5
-
72
-
-
34547454920
-
Nucleation of protein fibrillation by nanoparticles
-
Linse, S., Cabaleiro-Lago, C., Xue, W. F., Lynch, I., Lindman, S., Thulin, E., Radford, S. E., and Dawson, K. A. (2007) Nucleation of protein fibrillation by nanoparticles. Proc. Natl. Acad. Sci. U.S.A. 104, 8691-8696
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 8691-8696
-
-
Linse, S.1
Cabaleiro-Lago, C.2
Xue, W.F.3
Lynch, I.4
Lindman, S.5
Thulin, E.6
Radford, S.E.7
Dawson, K.A.8
-
73
-
-
84863012541
-
Depth of α-synuclein in a bilayer determined by fluorescence, neutron reflectometry, and computation
-
Pfefferkorn, C. M., Heinrich, F., Sodt, A. J., Maltsev, A. S., Pastor, R. W., and Lee, J. C. (2012) Depth of α-synuclein in a bilayer determined by fluorescence, neutron reflectometry, and computation. Biophys. J. 102, 613-621
-
(2012)
Biophys. J.
, vol.102
, pp. 613-621
-
-
Pfefferkorn, C.M.1
Heinrich, F.2
Sodt, A.J.3
Maltsev, A.S.4
Pastor, R.W.5
Lee, J.C.6
-
74
-
-
84892178364
-
Quantification of the concentration of Aβ42 propagons during the lag phase by an amyloid chain reaction assay
-
Arosio, P., Cukalevski, R., Frohm, B., Knowles, T. P., and Linse, S. (2014) Quantification of the concentration of Aβ42 propagons during the lag phase by an amyloid chain reaction assay. J. Am. Chem. Soc. 136, 219-225
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 219-225
-
-
Arosio, P.1
Cukalevski, R.2
Frohm, B.3
Knowles, T.P.4
Linse, S.5
-
75
-
-
84903696629
-
Differences in nucleation behaviour underlie the contrasting aggregation pathways of the Aβ40 and Aβ42 peptide
-
Meisl, G., Yang, X., Hellstrand, E., Frohm, B., Kirkegaard, J. B., Cohen, S. I., Dobson, C. M., Linse, S., and Knowles, T. P. (2014) Differences in nucleation behaviour underlie the contrasting aggregation pathways of the Aβ40 and Aβ42 peptide. Proc. Natl. Sci. Acad. U.S.A. 111, 9384-9389
-
(2014)
Proc. Natl. Sci. Acad. U.S.A.
, vol.111
, pp. 9384-9389
-
-
Meisl, G.1
Yang, X.2
Hellstrand, E.3
Frohm, B.4
Kirkegaard, J.B.5
Cohen, S.I.6
Dobson, C.M.7
Linse, S.8
Knowles, T.P.9
-
76
-
-
0028885854
-
GM1 ganglioside-bound amyloid β-protein (A β): A possible form of preamyloid in Alzheimer's disease
-
Yanagisawa, K., Odaka, A., Suzuki, N., and Ihara, Y. (1995) GM1 ganglioside-bound amyloid β-protein (A β): a possible form of preamyloid in Alzheimer's disease. Nat. Med. 1, 1062-1066
-
(1995)
Nat. Med.
, vol.1
, pp. 1062-1066
-
-
Yanagisawa, K.1
Odaka, A.2
Suzuki, N.3
Ihara, Y.4
-
77
-
-
48549100652
-
Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease - A review
-
Ariga, T., McDonald, M. P., and Yu, R. K. (2008) Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease-a review. J. Lipid Res. 49, 1157-1175
-
(2008)
J. Lipid Res.
, vol.49
, pp. 1157-1175
-
-
Ariga, T.1
McDonald, M.P.2
Yu, R.K.3
-
78
-
-
84899068704
-
Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes
-
Hong, S., Ostaszewski, B. L., Yang, T., O'Malley, T. T., Jin, M., Yanagisawa, K., Li, S., Bartels, T., and Selkoe, D. J. (2014) Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes. Neuron 82, 308-319
-
(2014)
Neuron
, vol.82
, pp. 308-319
-
-
Hong, S.1
Ostaszewski, B.L.2
Yang, T.3
O'Malley, T.T.4
Jin, M.5
Yanagisawa, K.6
Li, S.7
Bartels, T.8
Selkoe, D.J.9
-
79
-
-
0035816709
-
Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein, an endogenous seed for Alzheimer amyloid
-
Kakio, A., Nishimoto, S. I., Yanagisawa, K., Kozutsumi, Y., and Matsuzaki, K. (2001) Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein, an endogenous seed for Alzheimer amyloid. J. Biol. Chem. 276, 24985-24990
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24985-24990
-
-
Kakio, A.1
Nishimoto, S.I.2
Yanagisawa, K.3
Kozutsumi, Y.4
Matsuzaki, K.5
-
80
-
-
77953235479
-
Aβ polymerization through interaction with membrane gangliosides
-
Matsuzaki, K., Kato, K., and Yanagisawa, K. (2010) Aβ polymerization through interaction with membrane gangliosides. Biochim. Biophys. Acta 1801, 868-877
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 868-877
-
-
Matsuzaki, K.1
Kato, K.2
Yanagisawa, K.3
-
81
-
-
84866555624
-
Potential contribution of exosomes to the prion-like propagation of lesions in Alzheimer's disease
-
Vingtdeux, V., Sergeant, N., and Buée, L. (2012) Potential contribution of exosomes to the prion-like propagation of lesions in Alzheimer's disease. Front. Physiol. 3, 229
-
(2012)
Front. Physiol.
, vol.3
, pp. 229
-
-
Vingtdeux, V.1
Sergeant, N.2
Buée, L.3
-
82
-
-
84859554327
-
Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-β peptide
-
Keilani, S., Lun, Y., Stevens, A. C., Williams, H. N., Sjoberg, E. R., Khanna, R., Valenzano, K. J., Checler, F., Buxbaum, J. D., Yanagisawa, K., Lockhart, D. J., Wustman, B. A., and Gandy, S. (2012) Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-β peptide. J. Neurosci. 32, 5223-5236
-
(2012)
J. Neurosci.
, vol.32
, pp. 5223-5236
-
-
Keilani, S.1
Lun, Y.2
Stevens, A.C.3
Williams, H.N.4
Sjoberg, E.R.5
Khanna, R.6
Valenzano, K.J.7
Checler, F.8
Buxbaum, J.D.9
Yanagisawa, K.10
Lockhart, D.J.11
Wustman, B.A.12
Gandy, S.13
-
83
-
-
84866529985
-
Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove
-
Dehay, B., Martinez-Vicente, M., Ramirez, A., Perier, C., Klein, C., Vila, M., and Bezard, E. (2012) Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove. Autophagy 8, 1389-1391
-
(2012)
Autophagy
, vol.8
, pp. 1389-1391
-
-
Dehay, B.1
Martinez-Vicente, M.2
Ramirez, A.3
Perier, C.4
Klein, C.5
Vila, M.6
Bezard, E.7
-
84
-
-
84879607073
-
Lysosomal impairment in Parkinson's disease
-
Dehay, B., Martinez-Vicente, M., Caldwell, G. A., Caldwell, K. A., Yue, Z., Cookson, M. R., Klein, C., Vila, M., and Bezard, E. (2013) Lysosomal impairment in Parkinson's disease. Mov. Disord. 28, 725-732
-
(2013)
Mov. Disord.
, vol.28
, pp. 725-732
-
-
Dehay, B.1
Martinez-Vicente, M.2
Caldwell, G.A.3
Caldwell, K.A.4
Yue, Z.5
Cookson, M.R.6
Klein, C.7
Vila, M.8
Bezard, E.9
-
85
-
-
84891905725
-
Extracellular monomeric Tau is sufficient to initiate the spread of Tau pathology
-
Michel, C. H., Kumar, S., Pinotsi, D., Tunnacliffe, A., St George-Hyslop, P., Mandelkow, E., Mandelkow, E. M., Kaminski, C. F., and Kaminski Schierle, G. S. (2014) Extracellular monomeric Tau is sufficient to initiate the spread of Tau pathology. J. Biol. Chem. 289, 956-967
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 956-967
-
-
Michel, C.H.1
Kumar, S.2
Pinotsi, D.3
Tunnacliffe, A.4
St George-Hyslop, P.5
Mandelkow, E.6
Mandelkow, E.M.7
Kaminski, C.F.8
Kaminski Schierle, G.S.9
|