Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2

Journal of Biological Chemistry

Volumn 290, Issue 5, 2015, Pages 3057-3068

  Fishel, Melissa L ^a   Wu, Xue ^a   Devlin, Cecilia M ^a   Logsdon, Derek P ^a   Jiang, Yanlin ^a   Luo, Meihua ^a   He, Ying ^a   Yu, Zhangsheng ^a   Tong, Yan ^a   Lipking, Kelsey P ^a   Maitra, Anirban ^b,c   Rajeshkumar, N V ^b,d   Scandura, Glenda ^a   Kelley, Mark R ^a   Ivan, Mircea ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d INTREXON CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

ACTIVATOR PROTEIN-1; DOWNSTREAM TARGET; DUCTAL ADENOCARCINOMAS; HYPOXIA-INDUCIBLE FACTOR 1; MULTIFUNCTIONAL PROTEIN; REACTIVE OXYGEN SPECIES; SMALL MOLECULE INHIBITOR; THERAPEUTIC TARGETS;

TUMORS;

HEME OXYGENASE 1; REACTIVE OXYGEN METABOLITE; REDOX EFFECTOR FACTOR 1; TRANSCRIPTION FACTOR NRF2; APEX1 PROTEIN, HUMAN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; NFE2L2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; TRANSCRIPTION INITIATION; TUMOR CELL; UPREGULATION; GENETICS; METABOLISM; PANCREAS TUMOR; TUMOR CELL LINE;

CELL LINE, TUMOR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; HUMANS; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; PANCREATIC NEOPLASMS; REACTIVE OXYGEN SPECIES;

EID: 84921888012     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.621995     Document Type: Article

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