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Volumn 66, Issue , 2015, Pages 80-89

Detection strategies for methylated and hypermethylated DNA

Author keywords

Aberrant DNA methylation; Cancer assay; Disease diagnosis; DNA hydroxymethylation; DNA hypermethylation; DNA hypomethylation; DNA methylation; Electrochemical method; Methylation analysis; Optical method

Indexed keywords

ALKYLATION; DIAGNOSIS; DISEASES; DNA SEQUENCES; METHYLATION;

EID: 84921887894     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2014.11.013     Document Type: Review
Times cited : (29)

References (99)
  • 1
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li E., Beard C., Jaenisch R. Role for DNA methylation in genomic imprinting. Nature 1993, 366:362-365.
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 4
    • 0019510628 scopus 로고
    • Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation
    • Mohandas T., Sparkes R.S., Shapiro L.J. Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. Science 1981, 211:393-396.
    • (1981) Science , vol.211 , pp. 393-396
    • Mohandas, T.1    Sparkes, R.S.2    Shapiro, L.J.3
  • 7
    • 31344466008 scopus 로고    scopus 로고
    • DNA methylation and gene silencing in cancer
    • Baylin S.B. DNA methylation and gene silencing in cancer. Nat. Clin. Pract. Oncol 2005, 2(Suppl. 1):S4-S11.
    • (2005) Nat. Clin. Pract. Oncol , vol.2 , pp. S4-S11
    • Baylin, S.B.1
  • 8
    • 80052179100 scopus 로고    scopus 로고
    • Genome-wide combination profiling of DNA copy number and methylation for deciphering biomarkers in non-small cell lung cancer patients
    • Son J.W., Jeong K.J., Jean W.-S., Park S.Y., Jheon S., Cho H.M., et al. Genome-wide combination profiling of DNA copy number and methylation for deciphering biomarkers in non-small cell lung cancer patients. Cancer Lett 2011, 311:29-37.
    • (2011) Cancer Lett , vol.311 , pp. 29-37
    • Son, J.W.1    Jeong, K.J.2    Jean, W.-S.3    Park, S.Y.4    Jheon, S.5    Cho, H.M.6
  • 9
    • 81155123078 scopus 로고    scopus 로고
    • Quantitative detection of RASSF1A DNA promoter methylation in tumors and serum of patients with serous epithelial ovarian cancer
    • Bondurant A.E., Huang Z., Whitaker R.S., Simel L.R., Berchuck A., Murphy S.K. Quantitative detection of RASSF1A DNA promoter methylation in tumors and serum of patients with serous epithelial ovarian cancer. Gynecol. Oncol 2011, 123:581-587.
    • (2011) Gynecol. Oncol , vol.123 , pp. 581-587
    • Bondurant, A.E.1    Huang, Z.2    Whitaker, R.S.3    Simel, L.R.4    Berchuck, A.5    Murphy, S.K.6
  • 10
    • 84876937056 scopus 로고    scopus 로고
    • DNA methylation biomarkers of stool and blood for early detection of colon cancer
    • Hong L., Ahuja N. DNA methylation biomarkers of stool and blood for early detection of colon cancer. Genet. Test. Mol. Biomarkers 2013, 17:401-406.
    • (2013) Genet. Test. Mol. Biomarkers , vol.17 , pp. 401-406
    • Hong, L.1    Ahuja, N.2
  • 11
    • 84858983373 scopus 로고    scopus 로고
    • DNA methylation signatures for breast cancer classification and prognosis
    • Szyf M. DNA methylation signatures for breast cancer classification and prognosis. Genome Med 2012, 4:26.
    • (2012) Genome Med , vol.4 , pp. 26
    • Szyf, M.1
  • 13
    • 84890266248 scopus 로고    scopus 로고
    • Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas
    • Renner M., Wolf T., Meyer H., Hartmann W., Penzel R., Ulrich A., et al. Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas. Genome Biol 2013, 14:r137.
    • (2013) Genome Biol , vol.14 , pp. r137
    • Renner, M.1    Wolf, T.2    Meyer, H.3    Hartmann, W.4    Penzel, R.5    Ulrich, A.6
  • 14
    • 84856732148 scopus 로고    scopus 로고
    • Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genes
    • Ammerpohl O., Haake A., Pellissery S., Giefing M., Richter J., Balint B., et al. Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genes. Leukemia 2012, 26:185-188.
    • (2012) Leukemia , vol.26 , pp. 185-188
    • Ammerpohl, O.1    Haake, A.2    Pellissery, S.3    Giefing, M.4    Richter, J.5    Balint, B.6
  • 15
    • 84891842006 scopus 로고    scopus 로고
    • Origins of aberrant DNA methylation in acute myeloid leukemia
    • Schoofs T., Berdel W.E., Müller-Tidow C. Origins of aberrant DNA methylation in acute myeloid leukemia. Leukemia 2014, 28:1-14.
    • (2014) Leukemia , vol.28 , pp. 1-14
    • Schoofs, T.1    Berdel, W.E.2    Müller-Tidow, C.3
  • 16
    • 0036844322 scopus 로고    scopus 로고
    • Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors
    • Zardo G., Tiirikainen M.I., Hong C., Misra A., Feuerstein B.G., Volik S., et al. Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors. Nat. Genet 2002, 32:453-458.
    • (2002) Nat. Genet , vol.32 , pp. 453-458
    • Zardo, G.1    Tiirikainen, M.I.2    Hong, C.3    Misra, A.4    Feuerstein, B.G.5    Volik, S.6
  • 17
    • 84885794483 scopus 로고    scopus 로고
    • Higher 5-hydroxymethylcytosine identifies immortal DNA strand chromosomes in asymmetrically self-renewing distributed stem cells
    • Huh Y.H., Cohen J., Sherley J.L. Higher 5-hydroxymethylcytosine identifies immortal DNA strand chromosomes in asymmetrically self-renewing distributed stem cells. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:16862-16867.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 16862-16867
    • Huh, Y.H.1    Cohen, J.2    Sherley, J.L.3
  • 18
    • 84937738273 scopus 로고    scopus 로고
    • 5-Hydroxymethylcytosine: a new player in brain disorders?
    • Cheng Y., Bernstein A., Chen D., Jin P. 5-Hydroxymethylcytosine: a new player in brain disorders?. Exp. Neurol 2014, http://doi.org/10.1016/j.expneurol.2014.05.008.
    • (2014) Exp. Neurol
    • Cheng, Y.1    Bernstein, A.2    Chen, D.3    Jin, P.4
  • 19
    • 84988375135 scopus 로고    scopus 로고
    • 5-hydroxymethylcytosine: a new insight into epigenetics in cancer
    • Ye C., Li L. 5-hydroxymethylcytosine: a new insight into epigenetics in cancer. Cancer Biol. Ther 2014, 15:10-15.
    • (2014) Cancer Biol. Ther , vol.15 , pp. 10-15
    • Ye, C.1    Li, L.2
  • 20
    • 84876139704 scopus 로고    scopus 로고
    • Clinical applications of DNA methylation biomarkers in colorectal cancer
    • Laird P.W., Lange C.P.E. Clinical applications of DNA methylation biomarkers in colorectal cancer. Epigenomics 2013, 5:105-108.
    • (2013) Epigenomics , vol.5 , pp. 105-108
    • Laird, P.W.1    Lange, C.P.E.2
  • 21
    • 34250364447 scopus 로고    scopus 로고
    • Towards clinical application of methylated DNA sequences as cancer biomarkers: a joint NCI's EDRN and NIST workshop on standards, methods, assays, reagents and tools
    • Kagan J., Srivastava S., Barker P.E., Belinsky S.A., Cairns P. Towards clinical application of methylated DNA sequences as cancer biomarkers: a joint NCI's EDRN and NIST workshop on standards, methods, assays, reagents and tools. Cancer Res 2007, 67:4545-4549.
    • (2007) Cancer Res , vol.67 , pp. 4545-4549
    • Kagan, J.1    Srivastava, S.2    Barker, P.E.3    Belinsky, S.A.4    Cairns, P.5
  • 22
    • 84919846390 scopus 로고    scopus 로고
    • Clinical applications of epigenetics in cardiovascular disease: the long road ahead
    • Aslibekyan S., Claas S.A., Arnett D.K. Clinical applications of epigenetics in cardiovascular disease: the long road ahead. Transl. Res 2014, 1-11.
    • (2014) Transl. Res , pp. 1-11
    • Aslibekyan, S.1    Claas, S.A.2    Arnett, D.K.3
  • 23
    • 0025060989 scopus 로고
    • A quantitative Hpall-PCR assay to measure methylation of DNA from a small number of cells
    • Singer-Sam J., LeBon J.M., Tanguay R.L., Riggs A.D. A quantitative Hpall-PCR assay to measure methylation of DNA from a small number of cells. Nucleic Acids Res 1990, 18:687.
    • (1990) Nucleic Acids Res , vol.18 , pp. 687
    • Singer-Sam, J.1    LeBon, J.M.2    Tanguay, R.L.3    Riggs, A.D.4
  • 25
    • 0026546877 scopus 로고
    • A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
    • Frommer M., McDonald L.E., Millar D.S., Collis C.M., Watt F., Grigg G.W., et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc. Natl. Acad. Sci. U.S.A. 1992, 89:1827-1831.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 1827-1831
    • Frommer, M.1    McDonald, L.E.2    Millar, D.S.3    Collis, C.M.4    Watt, F.5    Grigg, G.W.6
  • 28
    • 80052166888 scopus 로고    scopus 로고
    • Detection of TFPI2 methylation in the serum of colorectal cancer patients
    • Hibi K., Goto T., Shirahata A., Saito M., Kigawa G., Nemoto H., et al. Detection of TFPI2 methylation in the serum of colorectal cancer patients. Cancer Lett 2011, 311:96-100.
    • (2011) Cancer Lett , vol.311 , pp. 96-100
    • Hibi, K.1    Goto, T.2    Shirahata, A.3    Saito, M.4    Kigawa, G.5    Nemoto, H.6
  • 29
    • 0030738231 scopus 로고    scopus 로고
    • Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)
    • Gonzalgo M.L., Jones P.A. Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res 1997, 25:2529-2531.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2529-2531
    • Gonzalgo, M.L.1    Jones, P.A.2
  • 30
    • 42449142344 scopus 로고    scopus 로고
    • Sensitive melting analysis after real time- methylation specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection
    • Kristensen L.S., Mikeska T., Krypuy M., Dobrovic A. Sensitive melting analysis after real time- methylation specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection. Nucleic Acids Res 2008, 36:e42.
    • (2008) Nucleic Acids Res , vol.36 , pp. e42
    • Kristensen, L.S.1    Mikeska, T.2    Krypuy, M.3    Dobrovic, A.4
  • 31
    • 78049448562 scopus 로고    scopus 로고
    • Quantitative detection of DNA methylation states in minute amounts of DNA from body fluids
    • Paliwal A., Vaissière T., Herceg Z. Quantitative detection of DNA methylation states in minute amounts of DNA from body fluids. Methods 2010, 52:242-247.
    • (2010) Methods , vol.52 , pp. 242-247
    • Paliwal, A.1    Vaissière, T.2    Herceg, Z.3
  • 32
    • 0036144753 scopus 로고    scopus 로고
    • Enzymatic regional methylation assay: a novel method to quantify regional CpG methylation density
    • Galm O., Rountree M.R., Bachman K.E., Jair K.-W., Baylin S.B., Herman J.G. Enzymatic regional methylation assay: a novel method to quantify regional CpG methylation density. Genome Res 2002, 12:153-157.
    • (2002) Genome Res , vol.12 , pp. 153-157
    • Galm, O.1    Rountree, M.R.2    Bachman, K.E.3    Jair, K.-W.4    Baylin, S.B.5    Herman, J.G.6
  • 35
    • 70449904964 scopus 로고    scopus 로고
    • Determination of DNA methylation by COBRA: a comparative study of CGE with LIF detection and conventional gel electrophoresis
    • Goedecke S., Schlosser S., Mühlisch J., Hempel G., Frühwald M.C., Wünsch B. Determination of DNA methylation by COBRA: a comparative study of CGE with LIF detection and conventional gel electrophoresis. Electrophoresis 2009, 30:3063-3070.
    • (2009) Electrophoresis , vol.30 , pp. 3063-3070
    • Goedecke, S.1    Schlosser, S.2    Mühlisch, J.3    Hempel, G.4    Frühwald, M.C.5    Wünsch, B.6
  • 37
    • 84897464807 scopus 로고    scopus 로고
    • Array-based DNA methylation profiling in male infertility reveals allele-specific DNA methylation in PIWIL1 and PIWIL2
    • Friemel C., Ammerpohl O., Gutwein J., Schmutzler A.G., Caliebe A., Kautza M., et al. Array-based DNA methylation profiling in male infertility reveals allele-specific DNA methylation in PIWIL1 and PIWIL2. Fertil. Steril 2014, 101:1097-1103.
    • (2014) Fertil. Steril , vol.101 , pp. 1097-1103
    • Friemel, C.1    Ammerpohl, O.2    Gutwein, J.3    Schmutzler, A.G.4    Caliebe, A.5    Kautza, M.6
  • 38
    • 35348943352 scopus 로고    scopus 로고
    • Allele-specific extension on microarray for DNA methylation analysis
    • Wu Z., Luo J., Ge Q., Zhang D., Wang Y., Jia C., et al. Allele-specific extension on microarray for DNA methylation analysis. Anal. Chim. Acta 2007, 603:199-204.
    • (2007) Anal. Chim. Acta , vol.603 , pp. 199-204
    • Wu, Z.1    Luo, J.2    Ge, Q.3    Zhang, D.4    Wang, Y.5    Jia, C.6
  • 40
    • 77249137168 scopus 로고    scopus 로고
    • Principles and challenges of genomewide DNA methylation analysis
    • Laird P.W. Principles and challenges of genomewide DNA methylation analysis. Nat. Rev. Genet 2010, 11:191-203.
    • (2010) Nat. Rev. Genet , vol.11 , pp. 191-203
    • Laird, P.W.1
  • 41
    • 84897532058 scopus 로고    scopus 로고
    • DNA methylation detection and inhibitor screening based on the discrimination of the aggregation of long and short DNA on a negatively charged indium tin oxide microelectrode
    • Wei X., Ma X., Sun J.-J., Lin Z., Guo L., Qiu B., et al. DNA methylation detection and inhibitor screening based on the discrimination of the aggregation of long and short DNA on a negatively charged indium tin oxide microelectrode. Anal. Chem 2014, 86:3563-3567.
    • (2014) Anal. Chem , vol.86 , pp. 3563-3567
    • Wei, X.1    Ma, X.2    Sun, J.-J.3    Lin, Z.4    Guo, L.5    Qiu, B.6
  • 42
    • 50249093359 scopus 로고    scopus 로고
    • Fluorescent conjugated polyelectrolyte as an indicator for convenient detection of DNA methylation
    • Feng F., Wang H., Han L., Wang S. Fluorescent conjugated polyelectrolyte as an indicator for convenient detection of DNA methylation. J. Am. Chem. Soc 2008, 130:11338-11343.
    • (2008) J. Am. Chem. Soc , vol.130 , pp. 11338-11343
    • Feng, F.1    Wang, H.2    Han, L.3    Wang, S.4
  • 43
    • 84863923396 scopus 로고    scopus 로고
    • Sensitive and label-free DNA methylation detection by ligation- mediated hyperbranched rolling circle amplification
    • Cao A., Zhang C. Sensitive and label-free DNA methylation detection by ligation- mediated hyperbranched rolling circle amplification. Anal. Chem 2012, 84:6199-6205.
    • (2012) Anal. Chem , vol.84 , pp. 6199-6205
    • Cao, A.1    Zhang, C.2
  • 44
    • 84882797941 scopus 로고    scopus 로고
    • A new strategy for methylated DNA detection based on photoelectrochemical immunosensor using Bi2S3 nanorods, methyl bonding domain protein and anti-his tag antibody
    • Yin H., Sun B., Zhou Y., Wang M., Xu Z., Fu Z., et al. A new strategy for methylated DNA detection based on photoelectrochemical immunosensor using Bi2S3 nanorods, methyl bonding domain protein and anti-his tag antibody. Biosens. Bioelectron 2014, 51:103-108.
    • (2014) Biosens. Bioelectron , vol.51 , pp. 103-108
    • Yin, H.1    Sun, B.2    Zhou, Y.3    Wang, M.4    Xu, Z.5    Fu, Z.6
  • 45
    • 80054710268 scopus 로고    scopus 로고
    • Electrochemical DNA methylation detection for enzymatically digested CpG oligonucleotides
    • Kato D., Goto K., Fujii S., Takatsu A., Hirono S., Niwa O. Electrochemical DNA methylation detection for enzymatically digested CpG oligonucleotides. Anal. Chem 2011, 83:7595-7599.
    • (2011) Anal. Chem , vol.83 , pp. 7595-7599
    • Kato, D.1    Goto, K.2    Fujii, S.3    Takatsu, A.4    Hirono, S.5    Niwa, O.6
  • 46
    • 79955476939 scopus 로고    scopus 로고
    • Analysis of global DNA methylation by hydrophilic interaction ultra high-pressure liquid chromatography tandem mass spectrometry
    • Zhang J., Zhang L., Zhou K., Ye X., Liu C., Zhang L., et al. Analysis of global DNA methylation by hydrophilic interaction ultra high-pressure liquid chromatography tandem mass spectrometry. Anal. Biochem 2011, 413:164-170.
    • (2011) Anal. Biochem , vol.413 , pp. 164-170
    • Zhang, J.1    Zhang, L.2    Zhou, K.3    Ye, X.4    Liu, C.5    Zhang, L.6
  • 47
    • 61849094247 scopus 로고    scopus 로고
    • Detection method for methylation density on microarray using methyl-CpG-binding domain protein
    • Luo J., Zheng W., Wang Y., Wu Z., Bai Y., Lu Z. Detection method for methylation density on microarray using methyl-CpG-binding domain protein. Anal. Biochem 2009, 387:143-149.
    • (2009) Anal. Biochem , vol.387 , pp. 143-149
    • Luo, J.1    Zheng, W.2    Wang, Y.3    Wu, Z.4    Bai, Y.5    Lu, Z.6
  • 48
    • 79952817426 scopus 로고    scopus 로고
    • Hypermethylated DAPK in serum DNA of women with uterine leiomyoma is a biomarker not restricted to cancer
    • Häfner N., Diebolder H., Jansen L., Hoppe I., Dürst M., Runnebaum I.B. Hypermethylated DAPK in serum DNA of women with uterine leiomyoma is a biomarker not restricted to cancer. Gynecol. Oncol 2011, 121:224-229.
    • (2011) Gynecol. Oncol , vol.121 , pp. 224-229
    • Häfner, N.1    Diebolder, H.2    Jansen, L.3    Hoppe, I.4    Dürst, M.5    Runnebaum, I.B.6
  • 49
    • 84455169454 scopus 로고    scopus 로고
    • Single base extension reaction-based surface enhanced Raman spectroscopy for DNA methylation assay
    • Hu J., Zhang C. Single base extension reaction-based surface enhanced Raman spectroscopy for DNA methylation assay. Biosens. Bioelectron 2012, 31:451-457.
    • (2012) Biosens. Bioelectron , vol.31 , pp. 451-457
    • Hu, J.1    Zhang, C.2
  • 50
    • 60549084858 scopus 로고    scopus 로고
    • High-performance capillary electrophoretic method for the quantification of global DNA methylation: application to methotrexate-resistant cells
    • Li M., Hu S., Shen Z., He X., Tao S., Dong L., et al. High-performance capillary electrophoretic method for the quantification of global DNA methylation: application to methotrexate-resistant cells. Anal. Biochem 2009, 387:71-75.
    • (2009) Anal. Biochem , vol.387 , pp. 71-75
    • Li, M.1    Hu, S.2    Shen, Z.3    He, X.4    Tao, S.5    Dong, L.6
  • 51
    • 77957337980 scopus 로고    scopus 로고
    • Label-free DNA methylation analysis using opto-fluidic ring resonators
    • Suter J.D., Howard D.J., Shi H., Caldwell C.W., Fan X. Label-free DNA methylation analysis using opto-fluidic ring resonators. Biosens. Bioelectron 2010, 26:1016-1020.
    • (2010) Biosens. Bioelectron , vol.26 , pp. 1016-1020
    • Suter, J.D.1    Howard, D.J.2    Shi, H.3    Caldwell, C.W.4    Fan, X.5
  • 52
  • 54
    • 84874052472 scopus 로고    scopus 로고
    • Label-free real-time detection of DNA methylation based on quartz crystal microbalance measurement
    • Wang J., Zhu Z., Ma H. Label-free real-time detection of DNA methylation based on quartz crystal microbalance measurement. Anal. Chem 2013, 85:2096-2101.
    • (2013) Anal. Chem , vol.85 , pp. 2096-2101
    • Wang, J.1    Zhu, Z.2    Ma, H.3
  • 55
    • 41149156894 scopus 로고    scopus 로고
    • A nanocarbon film electrode as a platform for exploring DNA methylation
    • Kato D., Sekioka N., Ueda A., Kurita R., Hirono S., Suzuki K., et al. A nanocarbon film electrode as a platform for exploring DNA methylation. J. Am. Chem. Soc 2008, 130:3716-3717.
    • (2008) J. Am. Chem. Soc , vol.130 , pp. 3716-3717
    • Kato, D.1    Sekioka, N.2    Ueda, A.3    Kurita, R.4    Hirono, S.5    Suzuki, K.6
  • 56
    • 84884954823 scopus 로고    scopus 로고
    • A sensitive electrochemical method for DNA methyltransferase assay and inhibitor screening based on DNA methylation-sensitive cleavage
    • Xu Z., Wang M., Yin H., Ai S., Wang L., Pang J. A sensitive electrochemical method for DNA methyltransferase assay and inhibitor screening based on DNA methylation-sensitive cleavage. Electrochim. Acta 2013, 112:596-602.
    • (2013) Electrochim. Acta , vol.112 , pp. 596-602
    • Xu, Z.1    Wang, M.2    Yin, H.3    Ai, S.4    Wang, L.5    Pang, J.6
  • 57
    • 84887674276 scopus 로고    scopus 로고
    • Electrochemical assay for the signal-on detection of human DNA methyltransferase activity
    • Muren N.B., Barton J.K. Electrochemical assay for the signal-on detection of human DNA methyltransferase activity. J. Am. Chem. Soc 2013, 135:16632-16640.
    • (2013) J. Am. Chem. Soc , vol.135 , pp. 16632-16640
    • Muren, N.B.1    Barton, J.K.2
  • 58
    • 84875115399 scopus 로고    scopus 로고
    • Electrochemical strategy for sensing DNA methylation and DNA methyltransferase activity
    • Wang G.L., Zhou L.Y., Luo H.Q., Li N.B. Electrochemical strategy for sensing DNA methylation and DNA methyltransferase activity. Anal. Chim. Acta 2013, 768:76-81.
    • (2013) Anal. Chim. Acta , vol.768 , pp. 76-81
    • Wang, G.L.1    Zhou, L.Y.2    Luo, H.Q.3    Li, N.B.4
  • 59
    • 77955172789 scopus 로고    scopus 로고
    • Direct electrochemical detection of DNA methylation for retinoblastoma and CpG fragments using a nanocarbon film
    • Goto K., Kato D., Sekioka N., Ueda A., Hirono S., Niwa O. Direct electrochemical detection of DNA methylation for retinoblastoma and CpG fragments using a nanocarbon film. Anal. Biochem 2010, 405:59-66.
    • (2010) Anal. Biochem , vol.405 , pp. 59-66
    • Goto, K.1    Kato, D.2    Sekioka, N.3    Ueda, A.4    Hirono, S.5    Niwa, O.6
  • 60
    • 84874518778 scopus 로고    scopus 로고
    • Electrochemical evaluation of DNA methylation level based on the stoichiometric relationship between purine and pyrimidine bases
    • Wang P., Chen H., Tian J., Dai Z., Zou X. Electrochemical evaluation of DNA methylation level based on the stoichiometric relationship between purine and pyrimidine bases. Biosens. Bioelectron 2013, 45:34-39.
    • (2013) Biosens. Bioelectron , vol.45 , pp. 34-39
    • Wang, P.1    Chen, H.2    Tian, J.3    Dai, Z.4    Zou, X.5
  • 61
    • 72249087918 scopus 로고    scopus 로고
    • Use of adsorptive transfer stripping voltammetry for analyzing variations of cytosine methylation in DNA
    • Ioannou A., Alexiadou D., Kouidou S., Girousi S., Voulgaropoulos A. Use of adsorptive transfer stripping voltammetry for analyzing variations of cytosine methylation in DNA. Electroanalysis 2009, 21:2685-2692.
    • (2009) Electroanalysis , vol.21 , pp. 2685-2692
    • Ioannou, A.1    Alexiadou, D.2    Kouidou, S.3    Girousi, S.4    Voulgaropoulos, A.5
  • 62
    • 0031792779 scopus 로고    scopus 로고
    • Identification and characterization of a family of mammalian methyl-CpG binding proteins
    • Hendrich B., Bird A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol. Cell. Biol 1998, 18:6538-6547.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 6538-6547
    • Hendrich, B.1    Bird, A.2
  • 63
    • 84867036557 scopus 로고    scopus 로고
    • Development of a method to measure DNA methylation levels by using methyl CpG-binding protein and luciferase-fused zinc finger protein
    • Hiraoka D., Yoshida W., Abe K., Wakeda H., Hata K., Ikebukuro K. Development of a method to measure DNA methylation levels by using methyl CpG-binding protein and luciferase-fused zinc finger protein. Anal. Chem 2012, 84:8259-8264.
    • (2012) Anal. Chem , vol.84 , pp. 8259-8264
    • Hiraoka, D.1    Yoshida, W.2    Abe, K.3    Wakeda, H.4    Hata, K.5    Ikebukuro, K.6
  • 64
    • 77953592498 scopus 로고    scopus 로고
    • Direct DNA methylation profiling using methyl binding domain proteins
    • Yu Y., Blair S., Gillespie D., Jensen R., Myszka D., Badran A.H., et al. Direct DNA methylation profiling using methyl binding domain proteins. Anal. Chem 2010, 82:5012-5019.
    • (2010) Anal. Chem , vol.82 , pp. 5012-5019
    • Yu, Y.1    Blair, S.2    Gillespie, D.3    Jensen, R.4    Myszka, D.5    Badran, A.H.6
  • 65
    • 84870842895 scopus 로고    scopus 로고
    • An electrochemical assay for DNA methylation, methyltransferase activity and inhibitor screening based on methyl binding domain protein
    • Yin H., Zhou Y., Xu Z., Chen L., Zhang D., Ai S. An electrochemical assay for DNA methylation, methyltransferase activity and inhibitor screening based on methyl binding domain protein. Biosens. Bioelectron 2013, 41:492-497.
    • (2013) Biosens. Bioelectron , vol.41 , pp. 492-497
    • Yin, H.1    Zhou, Y.2    Xu, Z.3    Chen, L.4    Zhang, D.5    Ai, S.6
  • 66
    • 84878359945 scopus 로고    scopus 로고
    • Ultrasensitive electrochemical immunoassay for DNA methyltransferase activity and inhibitor screening based on methyl binding domain protein of MeCP2 and enzymatic signal amplification
    • Yin H., Zhou Y., Xu Z., Wang M., Ai S. Ultrasensitive electrochemical immunoassay for DNA methyltransferase activity and inhibitor screening based on methyl binding domain protein of MeCP2 and enzymatic signal amplification. Biosens. Bioelectron 2013, 49:39-45.
    • (2013) Biosens. Bioelectron , vol.49 , pp. 39-45
    • Yin, H.1    Zhou, Y.2    Xu, Z.3    Wang, M.4    Ai, S.5
  • 68
    • 84880566878 scopus 로고    scopus 로고
    • Label-free and selective photoelectrochemical detection of chemical DNA methylation damage using DNA repair enzymes
    • Wu Y., Zhang B., Guo L.-H. Label-free and selective photoelectrochemical detection of chemical DNA methylation damage using DNA repair enzymes. Anal. Chem 2013, 85:6908-6914.
    • (2013) Anal. Chem , vol.85 , pp. 6908-6914
    • Wu, Y.1    Zhang, B.2    Guo, L.-H.3
  • 70
    • 84873676731 scopus 로고    scopus 로고
    • Semiconductor technology for early detection of DNA methylation for cancer: from concept to practice
    • Kalofonou M., Toumazou C. Semiconductor technology for early detection of DNA methylation for cancer: from concept to practice. Sens. Actuators B Chem 2013, 178:572-580.
    • (2013) Sens. Actuators B Chem , vol.178 , pp. 572-580
    • Kalofonou, M.1    Toumazou, C.2
  • 71
    • 84884471024 scopus 로고    scopus 로고
    • A membrane-based near-infrared fluorescence assay for detecting DNA methylation and transcription
    • Chen Y., Wang J. A membrane-based near-infrared fluorescence assay for detecting DNA methylation and transcription. Anal. Biochem 2013, 442:196-204.
    • (2013) Anal. Biochem , vol.442 , pp. 196-204
    • Chen, Y.1    Wang, J.2
  • 72
    • 79958265351 scopus 로고    scopus 로고
    • Detection method for quantifying global DNA methylation by fluorescence correlation spectroscopy
    • Umezu T., Ohyashiki K., Ohyashiki J.H. Detection method for quantifying global DNA methylation by fluorescence correlation spectroscopy. Anal. Biochem 2011, 415:145-150.
    • (2011) Anal. Biochem , vol.415 , pp. 145-150
    • Umezu, T.1    Ohyashiki, K.2    Ohyashiki, J.H.3
  • 73
    • 84858806394 scopus 로고    scopus 로고
    • Determination of DNA methylation using electrochemiluminescence with surface accumulable coreactant
    • Kurita R., Arai K., Nakamoto K., Kato D., Niwa O. Determination of DNA methylation using electrochemiluminescence with surface accumulable coreactant. Anal. Chem 2012, 84:1799-1803.
    • (2012) Anal. Chem , vol.84 , pp. 1799-1803
    • Kurita, R.1    Arai, K.2    Nakamoto, K.3    Kato, D.4    Niwa, O.5
  • 74
    • 66949139642 scopus 로고    scopus 로고
    • A simple, universal colorimetric assay for endonuclease/methyltransferase activity and inhibition based on an enzyme-responsive nanoparticle system
    • Song G., Chen C., Ren J., Qu X. A simple, universal colorimetric assay for endonuclease/methyltransferase activity and inhibition based on an enzyme-responsive nanoparticle system. ACS Nano 2009, 3:1183-1189.
    • (2009) ACS Nano , vol.3 , pp. 1183-1189
    • Song, G.1    Chen, C.2    Ren, J.3    Qu, X.4
  • 75
    • 77249135022 scopus 로고    scopus 로고
    • Cationic conjugated polymers for optical detection of DNA methylation, lesions, and single nucleotide polymorphisms
    • Duan X., Liu L., Feng F., Wang S. Cationic conjugated polymers for optical detection of DNA methylation, lesions, and single nucleotide polymorphisms. Acc. Chem. Res 2010, 43:260-270.
    • (2010) Acc. Chem. Res , vol.43 , pp. 260-270
    • Duan, X.1    Liu, L.2    Feng, F.3    Wang, S.4
  • 76
    • 75649112663 scopus 로고    scopus 로고
    • Enzymatic incorporation of multiple dyes for increased sensitivity in QD-FRET sensing for DNA methylation detection
    • Bailey V.J., Keeley B.P., Zhang Y., Ho Y.-P., Easwaran H., Brock M.V., et al. Enzymatic incorporation of multiple dyes for increased sensitivity in QD-FRET sensing for DNA methylation detection. Chembiochem 2010, 11:71-74.
    • (2010) Chembiochem , vol.11 , pp. 71-74
    • Bailey, V.J.1    Keeley, B.P.2    Zhang, Y.3    Ho, Y.-P.4    Easwaran, H.5    Brock, M.V.6
  • 77
    • 70349786386 scopus 로고    scopus 로고
    • Highly sensitive determination of microRNA using target-primed and branched rolling-circle amplification
    • Cheng Y., Zhang X., Li Z., Jiao X., Wang Y., Zhang Y. Highly sensitive determination of microRNA using target-primed and branched rolling-circle amplification. Angew. Chem. Int. Ed Engl 2009, 48:3268-3272.
    • (2009) Angew. Chem. Int. Ed Engl , vol.48 , pp. 3268-3272
    • Cheng, Y.1    Zhang, X.2    Li, Z.3    Jiao, X.4    Wang, Y.5    Zhang, Y.6
  • 78
    • 84871660360 scopus 로고    scopus 로고
    • Highly sensitive fluorescence assay of DNA methyltransferase activity via methylation-sensitive cleavage coupled with nicking enzyme-assisted signal amplification
    • Zhao Y., Chen F., Wu Y., Dong Y., Fan C. Highly sensitive fluorescence assay of DNA methyltransferase activity via methylation-sensitive cleavage coupled with nicking enzyme-assisted signal amplification. Biosens. Bioelectron 2013, 42:56-61.
    • (2013) Biosens. Bioelectron , vol.42 , pp. 56-61
    • Zhao, Y.1    Chen, F.2    Wu, Y.3    Dong, Y.4    Fan, C.5
  • 79
    • 82355191011 scopus 로고    scopus 로고
    • A carbon nanoparticle-based low-background biosensing platform for sensitive and label-free fluorescent assay of DNA methylation
    • Ouyang X., Liu J., Li J., Yang R. A carbon nanoparticle-based low-background biosensing platform for sensitive and label-free fluorescent assay of DNA methylation. Chem. Commun 2012, 48:88-90.
    • (2012) Chem. Commun , vol.48 , pp. 88-90
    • Ouyang, X.1    Liu, J.2    Li, J.3    Yang, R.4
  • 80
    • 84864380666 scopus 로고    scopus 로고
    • Electrogenerated chemiluminescence biosensing method for the detection of DNA methylation and assay of the methyltransferase activity
    • Li Y., Huang C., Zheng J., Qi H. Electrogenerated chemiluminescence biosensing method for the detection of DNA methylation and assay of the methyltransferase activity. Biosens. Bioelectron 2012, 38:407-410.
    • (2012) Biosens. Bioelectron , vol.38 , pp. 407-410
    • Li, Y.1    Huang, C.2    Zheng, J.3    Qi, H.4
  • 81
    • 84994229754 scopus 로고    scopus 로고
    • DNA methylation analysis by MALDI mass spectrometry
    • Second Edi
    • Tost J., Gut I.G. DNA methylation analysis by MALDI mass spectrometry. Encycl. Mol. Cell Biol. Mol. Med 2012, 1-40. Second Edi.
    • (2012) Encycl. Mol. Cell Biol. Mol. Med , pp. 1-40
    • Tost, J.1    Gut, I.G.2
  • 82
    • 67449108171 scopus 로고    scopus 로고
    • Enzymatic methylation of DNA in cultured human cells studied by stable isotope incorporation and mass spectrometry
    • Herring J.L., Rogstad D.K., Sowers L.C. Enzymatic methylation of DNA in cultured human cells studied by stable isotope incorporation and mass spectrometry. Chem. Res. Toxicol 2009, 22:1060-1068.
    • (2009) Chem. Res. Toxicol , vol.22 , pp. 1060-1068
    • Herring, J.L.1    Rogstad, D.K.2    Sowers, L.C.3
  • 83
    • 0036714169 scopus 로고    scopus 로고
    • A method to assess genomic DNA methylation using high-performance liquid chromatography/electrospray ionization mass spectrometry
    • Friso S., Choi S.-W., Dolnikowski G.G., Selhub J. A method to assess genomic DNA methylation using high-performance liquid chromatography/electrospray ionization mass spectrometry. Anal. Chem 2002, 74:4526-4531.
    • (2002) Anal. Chem , vol.74 , pp. 4526-4531
    • Friso, S.1    Choi, S.-W.2    Dolnikowski, G.G.3    Selhub, J.4
  • 84
    • 84893675090 scopus 로고    scopus 로고
    • Optimization of global DNA methylation measurement by LC-MS/MS and its application in lung cancer patients
    • Hu C.-W., Lee H., Chen J.-L., Li Y.-J., Chao M.-R. Optimization of global DNA methylation measurement by LC-MS/MS and its application in lung cancer patients. Anal. Bioanal. Chem 2013, 405:8859-8869.
    • (2013) Anal. Bioanal. Chem , vol.405 , pp. 8859-8869
    • Hu, C.-W.1    Lee, H.2    Chen, J.-L.3    Li, Y.-J.4    Chao, M.-R.5
  • 85
    • 0035139370 scopus 로고    scopus 로고
    • MALDI-TOF-MS analysis of protein and DNA
    • Bonk T., Humeny A. MALDI-TOF-MS analysis of protein and DNA. Neuroscientist 2001, 7:6-12.
    • (2001) Neuroscientist , vol.7 , pp. 6-12
    • Bonk, T.1    Humeny, A.2
  • 86
    • 84875463071 scopus 로고
    • Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers
    • Hillenkamp F., Karas M., Beavis R.C., Chait B.T. Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers. Anal. Chem 1991, 63:1193A-1203A.
    • (1991) Anal. Chem , vol.63 , pp. 1193A-1203A
    • Hillenkamp, F.1    Karas, M.2    Beavis, R.C.3    Chait, B.T.4
  • 87
    • 27644548948 scopus 로고    scopus 로고
    • Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry
    • Ehrich M., Nelson M.R., Stanssens P., Zabeau M., Liloglou T., Xinarianos G., et al. Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:15785-15790.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 15785-15790
    • Ehrich, M.1    Nelson, M.R.2    Stanssens, P.3    Zabeau, M.4    Liloglou, T.5    Xinarianos, G.6
  • 90
    • 84875192951 scopus 로고    scopus 로고
    • Detection and quantification of methylation in DNA using solid-state nanopores
    • Shim J., Humphreys G.I., Venkatesan B.M., Munz J.M., Zou X., Sathe C., et al. Detection and quantification of methylation in DNA using solid-state nanopores. Sci. Rep 2013, 3:1389.
    • (2013) Sci. Rep , vol.3 , pp. 1389
    • Shim, J.1    Humphreys, G.I.2    Venkatesan, B.M.3    Munz, J.M.4    Zou, X.5    Sathe, C.6
  • 91
    • 84886308865 scopus 로고    scopus 로고
    • Designing DNA interstrand lock for locus-specific methylation detection in a nanopore
    • Artticle number 2381
    • Kang I., Wang Y., Reagan C., Fu Y., Wang M.X., Gu L.-Q. Designing DNA interstrand lock for locus-specific methylation detection in a nanopore. Sci. Rep 2013, 3. Artticle number 2381. 10.1038/srep02381.
    • (2013) Sci. Rep , vol.3
    • Kang, I.1    Wang, Y.2    Reagan, C.3    Fu, Y.4    Wang, M.X.5    Gu, L.-Q.6
  • 93
    • 84857912089 scopus 로고    scopus 로고
    • Quantitative measurement of genome-wide DNA methylation by a reliable and cost-efficient enzyme-linked immunosorbent assay technique
    • Kremer D., Metzger S., Kolb-Bachofen V. Quantitative measurement of genome-wide DNA methylation by a reliable and cost-efficient enzyme-linked immunosorbent assay technique. Anal. Biochem 2012, 422:74-78.
    • (2012) Anal. Biochem , vol.422 , pp. 74-78
    • Kremer, D.1    Metzger, S.2    Kolb-Bachofen, V.3
  • 94
    • 54049121723 scopus 로고    scopus 로고
    • In situ detection of methylated DNA by histo endonuclease-linked detection of methylated DNA sites: a new principle of analysis of DNA methylation
    • Koji T., Kondo S., Hishikawa Y., An S., Sato Y. In situ detection of methylated DNA by histo endonuclease-linked detection of methylated DNA sites: a new principle of analysis of DNA methylation. Histochem. Cell Biol 2008, 130:917-925.
    • (2008) Histochem. Cell Biol , vol.130 , pp. 917-925
    • Koji, T.1    Kondo, S.2    Hishikawa, Y.3    An, S.4    Sato, Y.5
  • 95
    • 70349628902 scopus 로고    scopus 로고
    • Fluorescence polarization combined capillary electrophoresis immunoassay for the sensitive detection of genomic DNA methylation
    • Wang X., Song Y., Song M., Wang Z., Li T., Wang H. Fluorescence polarization combined capillary electrophoresis immunoassay for the sensitive detection of genomic DNA methylation. Anal. Chem 2009, 81:7885-7891.
    • (2009) Anal. Chem , vol.81 , pp. 7885-7891
    • Wang, X.1    Song, Y.2    Song, M.3    Wang, Z.4    Li, T.5    Wang, H.6
  • 96
    • 84859317392 scopus 로고    scopus 로고
    • A simple colo rimetric detection of DNA methylation
    • Ge C., Fang Z., Chen J., Liu J., Lu X., Zeng L. A simple colo rimetric detection of DNA methylation. Analyst 2012, 137:2032-2035.
    • (2012) Analyst , vol.137 , pp. 2032-2035
    • Ge, C.1    Fang, Z.2    Chen, J.3    Liu, J.4    Lu, X.5    Zeng, L.6
  • 98
    • 74949087173 scopus 로고    scopus 로고
    • Methylated DNA immunoprecipitation and microarray-based analysis: detection of DNA methylation in breast cancer cell lines
    • Weng Y.-I., Huang T.H.-M., Yan P.S. Methylated DNA immunoprecipitation and microarray-based analysis: detection of DNA methylation in breast cancer cell lines. Methods Mol. Biol 2009, 590:165-176.
    • (2009) Methods Mol. Biol , vol.590 , pp. 165-176
    • Weng, Y.-I.1    Huang, T.H.-M.2    Yan, P.S.3
  • 99
    • 84865749932 scopus 로고    scopus 로고
    • DNA methylation analysis triggered by bulge specific immuno-recognition
    • Kurita R., Niwa O. DNA methylation analysis triggered by bulge specific immuno-recognition. Anal. Chem 2012, 84:7533-7538.
    • (2012) Anal. Chem , vol.84 , pp. 7533-7538
    • Kurita, R.1    Niwa, O.2


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