Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury

Journal of Clinical Investigation

Volumn 122, Issue 1, 2012, Pages 267-279

  Yoshioka, Jun ^a   Chutkow, William A ^a   Lee, Samuel ^a   Kim, Jae Bum ^a   Yan, Jie ^a   Tian, Rong ^a,d   Lindsey, Merry L ^b   Feener, Edward P ^a   Seidman, Christine E ^a   Seidman, Jonathan G ^a   Lee, Richard T ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; LACTIC ACID; TAMOXIFEN; THIOREDOXIN INTERACTING PROTEIN;

ANAEROBIC GLYCOLYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; FUNCTIONAL PROTEOMICS; GENE DELETION; GENE EXPRESSION; GENE REPRESSION; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HYPOXIA; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; NUCLEOTIDE METABOLISM; OXYGEN CONSUMPTION; PRIORITY JOURNAL; REPERFUSION INJURY;

ADENOSINE TRIPHOSPHATE; ANAEROBIOSIS; ANIMALS; CARRIER PROTEINS; ENERGY METABOLISM; FEMALE; GLYCOLYSIS; HUMANS; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MODELS, CARDIOVASCULAR; MYOCARDIAL REPERFUSION INJURY; THIOREDOXINS;

EID: 84855420336     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI44927     Document Type: Article

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