메뉴 건너뛰기




Volumn 383, Issue , 2014, Pages 27-54

Microbicide dosage forms

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; ASTODRIMER; CARRAGEENAN; CELLULOSE DERIVATIVE; DAPIVIRINE; DAPIVIRINE PLUS DS 003; EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; ESTRADIOL; ESTRADIOL ACETATE; ETHINYLESTRADIOL PLUS ETONOGESTREL; HYDROXYLETHYLCELLULOSE; MICROBICIDE; PLACEBO; POLYETHYLENE; POLYMACON; POLYPROPYLENE; SILASTIC; TENOFOVIR; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DRUG DOSAGE FORM;

EID: 84921696480     PISSN: 0070217X     EISSN: 21969965     Source Type: Book Series    
DOI: 10.1007/82_2013_357     Document Type: Article
Times cited : (24)

References (157)
  • 1
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Abdool Karim Q, Abdool Karim SS et al (2010) Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 329(5996):1168–1174
    • (2010) Science , vol.329 , Issue.5996 , pp. 1168-1174
    • Abdool Karim, Q.1    Abdool Karim, S.S.2
  • 2
    • 79954804509 scopus 로고    scopus 로고
    • Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women
    • Abdool Karim SS, Richardson BA et al (2011) Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women. AIDS 25(7):957–966
    • (2011) AIDS , vol.25 , Issue.7 , pp. 957-966
    • Abdool Karim, S.S.1    Richardson, B.A.2
  • 3
    • 43449092562 scopus 로고    scopus 로고
    • Mucosal irritation potential of personal lubricants relates to product osmolality as detected by the slug mucosal irritation assay
    • Adriaens E, Remon JP (2008) Mucosal irritation potential of personal lubricants relates to product osmolality as detected by the slug mucosal irritation assay. Sex Transm Dis 35(5):512–516
    • (2008) Sex Transm Dis , vol.35 , Issue.5 , pp. 512-516
    • Adriaens, E.1    Remon, J.P.2
  • 4
    • 84857125328 scopus 로고    scopus 로고
    • Formulation and delivery of microbicides
    • Agashe H, Hu M et al (2012) Formulation and delivery of microbicides. Curr HIV Res 10(1):88–96
    • (2012) Curr HIV Res , vol.10 , Issue.1 , pp. 88-96
    • Agashe, H.1    Hu, M.2
  • 5
    • 84857131210 scopus 로고    scopus 로고
    • Development and characterization of a vaginal film containing dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), for prevention of HIV-1 sexual transmission
    • Akil A, Parniak MA et al (2011) Development and characterization of a vaginal film containing dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), for prevention of HIV-1 sexual transmission. Drug Deliv Transl Res 1(3):209–222
    • (2011) Drug Deliv Transl Res , vol.1 , Issue.3 , pp. 209-222
    • Akil, A.1    Parniak, M.A.2
  • 6
    • 3242796693 scopus 로고    scopus 로고
    • Why consider vaginal drug administration?
    • Alexander NJ, Baker E et al (2004) Why consider vaginal drug administration? Fertil Steril 82(1):1–12
    • (2004) Fertil Steril , vol.82 , Issue.1 , pp. 1-12
    • Alexander, N.J.1    Baker, E.2
  • 7
    • 84921641965 scopus 로고    scopus 로고
    • Contraceptive diaphragm
    • Austin GD, Colburn TJ et al (1998) Contraceptive diaphragm. US patent Number 5, 900
    • (1998) US patent , vol.5 , pp. 900
    • Austin, G.D.1    Colburn, T.J.2
  • 8
    • 33746641829 scopus 로고    scopus 로고
    • Modulation of anisotropy in electrospun tissue-engineering scaffolds: Analysis of fiber alignment by the fast Fourier transform
    • Ayres C, Bowlin GL et al (2006) Modulation of anisotropy in electrospun tissue-engineering scaffolds: analysis of fiber alignment by the fast Fourier transform. Biomaterials 27(32):5524–5534
    • (2006) Biomaterials , vol.27 , Issue.32 , pp. 5524-5534
    • Ayres, C.1    Bowlin, G.L.2
  • 9
    • 84870318366 scopus 로고    scopus 로고
    • Drug-eluting fibers for HIV-1 inhibition and contraception
    • Ball C, Krogstad E et al (2012) Drug-eluting fibers for HIV-1 inhibition and contraception. PLoS One 7(11):e49792
    • (2012) PLoS One , vol.7 , Issue.11
    • Ball, C.1    Krogstad, E.2
  • 10
    • 79961125688 scopus 로고    scopus 로고
    • In vitro evaluation of mucoadhesive vaginal tablets of antifungal drugs prepared with thiolated polymer and development of a new dissolution technique for vaginal formulations
    • Baloglu E, Ay Senyigit Z et al (2011) In vitro evaluation of mucoadhesive vaginal tablets of antifungal drugs prepared with thiolated polymer and development of a new dissolution technique for vaginal formulations. Chem Pharm Bull (Tokyo) 59(8):952–958
    • (2011) Chem Pharm Bull (Tokyo) , vol.59 , Issue.8 , pp. 952-958
    • Baloglu, E.1    Ay Senyigit, Z.2
  • 11
    • 33847390394 scopus 로고    scopus 로고
    • Microbicide drug candidates to prevent HIV infection
    • Balzarini J, Van Damme L (2007) Microbicide drug candidates to prevent HIV infection. Lancet 369(9563):787–797
    • (2007) Lancet , vol.369 , Issue.9563 , pp. 787-797
    • Balzarini, J.1    Van Damme, L.2
  • 12
    • 80054773666 scopus 로고    scopus 로고
    • Pharmacokinetics and placental transfer of single-dose tenofovir 1% vaginal gel in term pregnancy
    • Beigi R, Noguchi L et al (2011) Pharmacokinetics and placental transfer of single-dose tenofovir 1% vaginal gel in term pregnancy. J Infect Dis 204(10):1527–1531
    • (2011) J Infect Dis , vol.204 , Issue.10 , pp. 1527-1531
    • Beigi, R.1    Noguchi, L.2
  • 13
    • 84859235750 scopus 로고    scopus 로고
    • Efficacy of oral metronidazole with vaginal clindamycin or vaginal probiotic for bacterial vaginosis: Randomised placebo-controlled double-blind trial
    • Bradshaw CS, Pirotta M et al (2012) Efficacy of oral metronidazole with vaginal clindamycin or vaginal probiotic for bacterial vaginosis: randomised placebo-controlled double-blind trial. PLoS One 7(4):e34540
    • (2012) PLoS One , vol.7 , Issue.4
    • Bradshaw, C.S.1    Pirotta, M.2
  • 14
    • 73549099755 scopus 로고    scopus 로고
    • Development of topical microbicides to prevent the sexual transmission of HIV
    • Buckheit RW Jr, Watson KM et al (2010) Development of topical microbicides to prevent the sexual transmission of HIV. Antiviral Res 85(1):142–158
    • (2010) Antiviral Res , vol.85 , Issue.1 , pp. 142-158
    • Buckheit, R.W.1    Watson, K.M.2
  • 15
    • 77952672525 scopus 로고    scopus 로고
    • RNA interference by nanofiber-based siRNA delivery system
    • Cao H, Jiang X et al (2010) RNA interference by nanofiber-based siRNA delivery system. J Control Release 144(2):203–212
    • (2010) J Control Release , vol.144 , Issue.2 , pp. 203-212
    • Cao, H.1    Jiang, X.2
  • 16
    • 84870423601 scopus 로고    scopus 로고
    • Sexual behavior, sexual attraction, and sexual identity in the United States: Data from the 2006–2008 national survey of family growth
    • Chandra A, Mosher WD et al (2011) Sexual behavior, sexual attraction, and sexual identity in the United States: data from the 2006–2008 national survey of family growth. Natl Health Stat Rep 36:1–36
    • (2011) Natl Health Stat Rep , vol.36 , pp. 1-36
    • Chandra, A.1    Mosher, W.D.2
  • 17
    • 84888355478 scopus 로고    scopus 로고
    • Prolong release bioadhesive vaginal film of anti-HIV drug (Zidovudine): Formualtion and in-vitro evaluation
    • Chatterjee A, Bhowmik B et al (2010) Prolong release bioadhesive vaginal film of anti-HIV drug (Zidovudine): formualtion and in-vitro evaluation. Int J Pharm Sci Res 1(3):28–37
    • (2010) Int J Pharm Sci Res , vol.1 , Issue.3 , pp. 28-37
    • Chatterjee, A.1    Bhowmik, B.2
  • 18
    • 84870378512 scopus 로고    scopus 로고
    • pH and temperature dual-sensitive liposome gel based on novel cleavable mPEG-Hz-CHEMS polymeric vaginal delivery system
    • Chen D, Sun K et al (2012) pH and temperature dual-sensitive liposome gel based on novel cleavable mPEG-Hz-CHEMS polymeric vaginal delivery system. Int J Nanomed 7:2621–2630
    • (2012) Int J Nanomed , vol.7 , pp. 2621-2630
    • Chen, D.1    Sun, K.2
  • 19
    • 36849041574 scopus 로고    scopus 로고
    • Functionalization of poly(L-lactide) nanofibrous scaffolds with bioactive collagen molecules
    • Chiu JB, Liu C et al (2007) Functionalization of poly(L-lactide) nanofibrous scaffolds with bioactive collagen molecules. J Biomed Mater Res A 83(4):1117–1127
    • (2007) J Biomed Mater Res A , vol.83 , Issue.4 , pp. 1117-1127
    • Chiu, J.B.1    Liu, C.2
  • 21
    • 84921697518 scopus 로고    scopus 로고
    • Development and preclinical pharmacokinetic evaluation of a tenofovir fast-dissolve vaginal tablet
    • Sydney, Australia
    • Clark M, Doncel G et al (2012) Development and preclinical pharmacokinetic evaluation of a tenofovir fast-dissolve vaginal tablet. Microbicides 2012, Sydney, Australia
    • (2012) Microbicides 2012
    • Clark, M.1    Doncel, G.2
  • 22
    • 78649749939 scopus 로고    scopus 로고
    • The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques
    • Cole AM, Patton DL et al (2010) The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. PLoS One 5(11):e15111
    • (2010) PLoS One , vol.5 , Issue.11
    • Cole, A.M.1    Patton, D.L.2
  • 23
    • 33645841647 scopus 로고    scopus 로고
    • Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy
    • Courtney T, Sacks MS et al (2006) Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy. Biomaterials 27(19):3631–3638
    • (2006) Biomaterials , vol.27 , Issue.19 , pp. 3631-3638
    • Courtney, T.1    Sacks, M.S.2
  • 24
    • 0035460306 scopus 로고    scopus 로고
    • A multinational evaluation of the efficacy, safety and acceptability of the protectaid contraceptive sponge
    • Creatsas G, Guerrero E et al (2001) A multinational evaluation of the efficacy, safety and acceptability of the protectaid contraceptive sponge. Eur J Contracept Reprod Health Care 6(3):172–182
    • (2001) Eur J Contracept Reprod Health Care , vol.6 , Issue.3 , pp. 172-182
    • Creatsas, G.1    Guerrero, E.2
  • 25
    • 33744521872 scopus 로고    scopus 로고
    • Investigation of drug release and matrix degradation of electrospun poly(DL-lactide) fibers with paracetanol inoculation
    • Cui W, Li X et al (2006) Investigation of drug release and matrix degradation of electrospun poly(DL-lactide) fibers with paracetanol inoculation. Biomacromolecules 7(5):1623–1629
    • (2006) Biomacromolecules , vol.7 , Issue.5 , pp. 1623-1629
    • Cui, W.1    Li, X.2
  • 26
    • 77953984131 scopus 로고    scopus 로고
    • Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clindamycin phosphate
    • Dobaria N, Mashru R (2010) Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clindamycin phosphate. Pharm Dev Technol 15(4):405–414
    • (2010) Pharm Dev Technol , vol.15 , Issue.4 , pp. 405-414
    • Dobaria, N.1    Mashru, R.2
  • 27
    • 70449524333 scopus 로고    scopus 로고
    • A novel itraconazole bioadhesive film for vaginal delivery: Design, optimization, and physicodynamic characterization
    • Dobaria NB, Badhan AC et al (2009) A novel itraconazole bioadhesive film for vaginal delivery: design, optimization, and physicodynamic characterization. AAPS PharmSciTech 10(3):951–959
    • (2009) AAPS PharmSciTech , vol.10 , Issue.3 , pp. 951-959
    • Dobaria, N.B.1    Badhan, A.C.2
  • 28
    • 84869226461 scopus 로고
    • Medicated devices and methods
    • Duncan G (1970) Medicated devices and methods. US Patent Number 3, 439
    • (1970) US Patent , vol.3 , pp. 439
    • Duncan, G.1
  • 29
    • 33947512397 scopus 로고    scopus 로고
    • Applications of thermo-reversible pluronic F-127 gels in pharmaceutical formulations
    • Escobar-Chavez JJ, Lopez-Cervantes M et al (2006) Applications of thermo-reversible pluronic F-127 gels in pharmaceutical formulations. J Pharm Pharm Sci 9(3):339–358
    • (2006) J Pharm Pharm Sci , vol.9 , Issue.3 , pp. 339-358
    • Escobar-Chavez, J.J.1    Lopez-Cervantes, M.2
  • 30
    • 84926452325 scopus 로고    scopus 로고
    • Social and behavioural aspects of prevention poster session 9: Women P2-S9.06 Vaginal film microbicides for HIV prevention: A mixed methods study of women’s preferences
    • Fan M, Ferguson L, Rohan L, Meyn L, Hillier S (2011) Social and behavioural aspects of prevention poster session 9: Women P2-S9.06 Vaginal film microbicides for HIV prevention: a mixed methods study of women’s preferences. Sex Transm Infect 87:A263. http:// sti.bmj.com/content/87/Suppl_1/A263.1. doi:10.1136/sextrans-2011-050108.392
    • (2011) Sex Transm Infect , vol.87
    • Fan, M.1    Ferguson, L.2    Rohan, L.3    Meyn, L.4    Hillier, S.5
  • 31
    • 0002676005 scopus 로고
    • Measurement of drug release from topical gels using two types of apparatus
    • Fares H, Zatz J (1995) Measurement of drug release from topical gels using two types of apparatus. Pharm Technol 19(1):52–58
    • (1995) Pharm Technol , vol.19 , Issue.1 , pp. 52-58
    • Fares, H.1    Zatz, J.2
  • 32
    • 84921641963 scopus 로고    scopus 로고
    • Guidance for industry, nonsterile semisolid dosage forms, scale-up and postapproval changes: Chemistry, manufacturing, and controls
    • FDA (1997) Guidance for industry, nonsterile semisolid dosage forms, scale-up and postapproval changes: chemistry, manufacturing, and controls. In vitro release testing and in vivo bioequivalence documentation
    • (1997) vitro release testing and in vivo bioequivalence documentation
  • 33
    • 77956341686 scopus 로고    scopus 로고
    • Novel antibacterial nanofibrous PLLA scaffolds
    • Feng K, Sun H et al (2010) Novel antibacterial nanofibrous PLLA scaffolds. J Control Release 146(3):363–369
    • (2010) J Control Release , vol.146 , Issue.3 , pp. 363-369
    • Feng, K.1    Sun, H.2
  • 34
    • 79954493015 scopus 로고    scopus 로고
    • Controlled-release vaginal ring drug-delivery systems: A key strategy for the development of effective HIV microbicides
    • Fetherston SM, Malcolm RK et al (2010) Controlled-release vaginal ring drug-delivery systems: a key strategy for the development of effective HIV microbicides. Ther Deliv 1(6):785–802
    • (2010) Ther Deliv , vol.1 , Issue.6 , pp. 785-802
    • Fetherston, S.M.1    Malcolm, R.K.2
  • 35
    • 59749098155 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor
    • Fletcher P, Harman S et al (2009) Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother 53(2):487–495
    • (2009) Antimicrob Agents Chemother , vol.53 , Issue.2 , pp. 487-495
    • Fletcher, P.1    Harman, S.2
  • 36
    • 0038506158 scopus 로고    scopus 로고
    • New contraceptive choices across reproductive life
    • Foran TM (2003) New contraceptive choices across reproductive life. Med J Aust 178(12):616–620
    • (2003) Med J Aust , vol.178 , Issue.12 , pp. 616-620
    • Foran, T.M.1
  • 37
    • 81255157679 scopus 로고    scopus 로고
    • Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc
    • Forbes CJ, Lowry D et al (2011) Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc. J Control Release 156(2):161–169
    • (2011) J Control Release , vol.156 , Issue.2 , pp. 161-169
    • Forbes, C.J.1    Lowry, D.2
  • 38
    • 0344845214 scopus 로고    scopus 로고
    • Ketoprofen: Release from, permeation across and rheology of simple gel formulations that simulate increasing dryness
    • Gallagher SJ, Trottet L et al (2003) Ketoprofen: release from, permeation across and rheology of simple gel formulations that simulate increasing dryness. Int J Pharm 268(1–2):37–45
    • (2003) Int J Pharm , vol.268 , Issue.1-2 , pp. 37-45
    • Gallagher, S.J.1    Trottet, L.2
  • 39
    • 0034850435 scopus 로고    scopus 로고
    • Properties of a new acid-buffering bioadhesive vaginal formulation (ACIDFORM)
    • Garg S, Anderson RA et al (2001) Properties of a new acid-buffering bioadhesive vaginal formulation (ACIDFORM). Contraception 64(1):67–75
    • (2001) Contraception , vol.64 , Issue.1 , pp. 67-75
    • Garg, S.1    Anderson, R.A.2
  • 40
    • 18044393199 scopus 로고    scopus 로고
    • Development and characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel contraceptive antimicrobial agent
    • Garg S, Vermani K et al (2005) Development and characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel contraceptive antimicrobial agent. Pharm Res 22(4):584–595
    • (2005) Pharm Res , vol.22 , Issue.4 , pp. 584-595
    • Garg, S.1    Vermani, K.2
  • 41
    • 78649436881 scopus 로고    scopus 로고
    • Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets
    • Garg S, Goldman D et al (2010) Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets. Antiviral Res 88(Suppl 1):S19–S29
    • (2010) Antiviral Res , vol.88 , pp. S19-S29
    • Garg, S.1    Goldman, D.2
  • 42
    • 27444436820 scopus 로고    scopus 로고
    • A review of co-processed directly compressible excipients
    • Gohel MC, Jogani PD (2005) A review of co-processed directly compressible excipients. J Pharm Pharm Sci 8(1):76–93
    • (2005) J Pharm Pharm Sci , vol.8 , Issue.1 , pp. 76-93
    • Gohel, M.C.1    Jogani, P.D.2
  • 43
    • 34547475023 scopus 로고    scopus 로고
    • Electrospinning: A fascinating method for the preparation of ultrathin fibers
    • Greiner A, Wendorff JH (2007) Electrospinning: a fascinating method for the preparation of ultrathin fibers. Angew Chem Int Ed Engl 46(30):5670–5703
    • (2007) Angew Chem Int Ed Engl , vol.46 , Issue.30 , pp. 5670-5703
    • Greiner, A.1    Wendorff, J.H.2
  • 44
    • 0037092619 scopus 로고    scopus 로고
    • Hydrogels: From controlled release to pH-responsive drug delivery
    • Gupta P, Vermani K et al (2002) Hydrogels: from controlled release to pH-responsive drug delivery. Drug Discov Today 7(10):569–579
    • (2002) Drug Discov Today , vol.7 , Issue.10 , pp. 569-579
    • Gupta, P.1    Vermani, K.2
  • 45
    • 54849431632 scopus 로고    scopus 로고
    • Polyurethane intravaginal ring for controlled delivery of dapivirine, a nonnucleoside reverse transcriptase inhibitor of HIV-1
    • Gupta KM, Pearce SM et al (2008) Polyurethane intravaginal ring for controlled delivery of dapivirine, a nonnucleoside reverse transcriptase inhibitor of HIV-1. J Pharm Sci 97(10):4228–4239
    • (2008) J Pharm Sci , vol.97 , Issue.10 , pp. 4228-4239
    • Gupta, K.M.1    Pearce, S.M.2
  • 46
    • 79952759340 scopus 로고    scopus 로고
    • Development and validation of a HPLC method for simultaneous determination of dapivirine and DS003 in combination microbicide tablet
    • Gupta J, Othman A et al (2011) Development and validation of a HPLC method for simultaneous determination of dapivirine and DS003 in combination microbicide tablet. Curr Pharm Anal 7(1):21–26
    • (2011) Curr Pharm Anal , vol.7 , Issue.1 , pp. 21-26
    • Gupta, J.1    Othman, A.2
  • 47
    • 84862782043 scopus 로고    scopus 로고
    • Vaginal film drug delivery of the pyrimidinedione IQP-0528 for the prevention of HIV infection
    • Ham AS, Rohan LC et al (2012) Vaginal film drug delivery of the pyrimidinedione IQP-0528 for the prevention of HIV infection. Pharm Res 29(7):1897–1907
    • (2012) Pharm Res , vol.29 , Issue.7 , pp. 1897-1907
    • Ham, A.S.1    Rohan, L.C.2
  • 48
    • 34447513849 scopus 로고    scopus 로고
    • Development of vaginal rings for sustained release of nonhormonal contraceptives and anti-HIV agents
    • Han YA, Singh M et al (2007) Development of vaginal rings for sustained release of nonhormonal contraceptives and anti-HIV agents. Contraception 76(2):132–138
    • (2007) Contraception , vol.76 , Issue.2 , pp. 132-138
    • Han, Y.A.1    Singh, M.2
  • 49
    • 65349175947 scopus 로고    scopus 로고
    • Orally dissolving film strips (ODFS): The final evolution of orally dissolving dosage forms
    • Hariharan M, Bogue BA (2009) Orally dissolving film strips (ODFS): the final evolution of orally dissolving dosage forms. Drug Deliv Technol 9(2):24–29
    • (2009) Drug Deliv Technol , vol.9 , Issue.2 , pp. 24-29
    • Hariharan, M.1    Bogue, B.A.2
  • 50
    • 84921742397 scopus 로고    scopus 로고
    • Candidate microbicides and their mechanisms of action
    • Epub ahead of print
    • Herrera C, Shattock RJ (2013) Candidate microbicides and their mechanisms of action. Curr Top Microbiol Immunol. http://link.springer.com/chapter/10.1007%2F82_2013_326. doi:10.1007/82_2013_326. Epub ahead of print
    • (2013) Curr Top Microbiol Immunol
    • Herrera, C.1    Shattock, R.J.2
  • 52
    • 33645923061 scopus 로고    scopus 로고
    • Encapsulating drugs in biodegradable ultrafine fibers through coaxial electrospinning
    • Huang ZM, He CL et al (2006) Encapsulating drugs in biodegradable ultrafine fibers through coaxial electrospinning. J Biomed Mater Res A 77(1):169–179
    • (2006) J Biomed Mater Res A , vol.77 , Issue.1 , pp. 169-179
    • Huang, Z.M.1    He, C.L.2
  • 53
    • 14844314490 scopus 로고    scopus 로고
    • The vagina as a route for systemic drug delivery
    • Hussain A, Ahsan F (2005) The vagina as a route for systemic drug delivery. J Control Release 103(2):301–313
    • (2005) J Control Release , vol.103 , Issue.2 , pp. 301-313
    • Hussain, A.1    Ahsan, F.2
  • 54
    • 77649271896 scopus 로고    scopus 로고
    • An anisotropic nanofiber/microsphere composite with controlled release of biomolecules for fibrous tissue engineering
    • Ionescu LC, Lee GC et al (2010) An anisotropic nanofiber/microsphere composite with controlled release of biomolecules for fibrous tissue engineering. Biomaterials 31(14):4113–4120
    • (2010) Biomaterials , vol.31 , Issue.14 , pp. 4113-4120
    • Ionescu, L.C.1    Lee, G.C.2
  • 57
    • 27744591467 scopus 로고    scopus 로고
    • A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents
    • Jiang H, Hu Y et al (2005) A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents. J Control Release 108(2–3):237–243
    • (2005) J Control Release , vol.108 , Issue.2-3 , pp. 237-243
    • Jiang, H.1    Hu, Y.2
  • 58
    • 45849112200 scopus 로고    scopus 로고
    • Nanofibrous scaffolds incorporating PDGF-BB microspheres induce chemokine expression and tissue neogenesis in vivo
    • Jin Q, Wei G et al (2008) Nanofibrous scaffolds incorporating PDGF-BB microspheres induce chemokine expression and tissue neogenesis in vivo. PLoS One 3(3):e1729
    • (2008) PLoS One , vol.3 , Issue.3
    • Jin, Q.1    Wei, G.2
  • 59
    • 33745477882 scopus 로고    scopus 로고
    • Acceptability of Praneem polyherbal vaginal tablet among HIV uninfected women & their male partners in Pune, India–Phase I study
    • Joglekar NS, Joshi SN et al (2006) Acceptability of Praneem polyherbal vaginal tablet among HIV uninfected women & their male partners in Pune, India–Phase I study. Indian J Med Res 123(4):547–552
    • (2006) Indian J Med Res , vol.123 , Issue.4 , pp. 547-552
    • Joglekar, N.S.1    Joshi, S.N.2
  • 60
    • 0033652088 scopus 로고    scopus 로고
    • The return of the pharmaceutical industry to the market of contraception
    • Johansson ED (2000) The return of the pharmaceutical industry to the market of contraception. Steroids 65(10–11):709–711
    • (2000) Steroids , vol.65 , Issue.10-11 , pp. 709-711
    • Johansson, E.D.1
  • 61
    • 75149116238 scopus 로고    scopus 로고
    • Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir
    • Johnson TJ, Gupta KM et al (2010) Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir. Eur J Pharm Sci 39(4):203–212
    • (2010) Eur J Pharm Sci , vol.39 , Issue.4 , pp. 203-212
    • Johnson, T.J.1    Gupta, K.M.2
  • 62
    • 84863173866 scopus 로고    scopus 로고
    • Safe and sustained vaginal delivery of pyrimidinedione HIV-1 inhibitors from polyurethane intravaginal rings
    • Johnson TJ, Srinivasan P et al (2012) Safe and sustained vaginal delivery of pyrimidinedione HIV-1 inhibitors from polyurethane intravaginal rings. Antimicrob Agents Chemother 56(3):1291–1299
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.3 , pp. 1291-1299
    • Johnson, T.J.1    Srinivasan, P.2
  • 63
    • 23844515523 scopus 로고    scopus 로고
    • Phase I safety study of Praneem polyherbal vaginal tablet use among HIV-uninfected women in Pune, India
    • Joshi SN, Katti U et al (2005) Phase I safety study of Praneem polyherbal vaginal tablet use among HIV-uninfected women in Pune, India. Trans R Soc Trop Med Hyg 99(10):769–774
    • (2005) Trans R Soc Trop Med Hyg , vol.99 , Issue.10 , pp. 769-774
    • Joshi, S.N.1    Katti, U.2
  • 64
    • 70350018361 scopus 로고    scopus 로고
    • Heterosexual anal intercourse among community and clinical settings in Cape Town, South Africa
    • Kalichman SC, Simbayi LC et al (2009) Heterosexual anal intercourse among community and clinical settings in Cape Town, South Africa. Sex Transm Infect 85(6):411–415
    • (2009) Sex Transm Infect , vol.85 , Issue.6 , pp. 411-415
    • Kalichman, S.C.1    Simbayi, L.C.2
  • 65
    • 79955077269 scopus 로고    scopus 로고
    • Designing of the mucoadhesive intravaginal spermicidal films
    • (PMCID: PMC3116316)
    • Kawarkhe S, Poddar SS (2010) Designing of the mucoadhesive intravaginal spermicidal films. Indian J Pharm Sci 72(5):652–655. doi:10.4103/0250-474X.78540 (PMCID: PMC3116316)
    • (2010) Indian J Pharm Sci , vol.72 , Issue.5 , pp. 652-655
    • Kawarkhe, S.1    Poddar, S.S.2
  • 66
    • 79551565205 scopus 로고    scopus 로고
    • A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel
    • Keller MJ, Madan RP et al (2011) A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel. PLoS One 6(1):e16475
    • (2011) PLoS One , vol.6 , Issue.1
    • Keller, M.J.1    Madan, R.P.2
  • 67
    • 2942557446 scopus 로고    scopus 로고
    • Mesoscopic spatial designs of nano- and microfiber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques
    • Kidoaki S, Kwon IK et al (2005) Mesoscopic spatial designs of nano- and microfiber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques. Biomaterials 26(1):37–46
    • (2005) Biomaterials , vol.26 , Issue.1 , pp. 37-46
    • Kidoaki, S.1    Kwon, I.K.2
  • 68
    • 30344476138 scopus 로고    scopus 로고
    • Structural features and mechanical properties of in situ-bonded meshes of segmented polyurethane electrospun from mixed solvents
    • Kidoaki S, Kwon IK et al (2006) Structural features and mechanical properties of in situ-bonded meshes of segmented polyurethane electrospun from mixed solvents. J Biomed Mater Res B Appl Biomater 76(1):219–229
    • (2006) J Biomed Mater Res B Appl Biomater , vol.76 , Issue.1 , pp. 219-229
    • Kidoaki, S.1    Kwon, I.K.2
  • 69
    • 77954314510 scopus 로고    scopus 로고
    • MMPs-responsive release of DNA from electrospun nanofibrous matrix for local gene therapy: In vitro and in vivo evaluation
    • Kim HS, Yoo HS (2010) MMPs-responsive release of DNA from electrospun nanofibrous matrix for local gene therapy: in vitro and in vivo evaluation. J Control Release 145(3):264–271
    • (2010) J Control Release , vol.145 , Issue.3 , pp. 264-271
    • Kim, H.S.1    Yoo, H.S.2
  • 70
    • 84858804932 scopus 로고    scopus 로고
    • State of the art in intravaginal ring technology for topical prophylaxis of HIV infection
    • Kiser PF, Johnson TJ et al (2012) State of the art in intravaginal ring technology for topical prophylaxis of HIV infection. AIDS Rev 14(1):62–77
    • (2012) AIDS Rev , vol.14 , Issue.1 , pp. 62-77
    • Kiser, P.F.1    Johnson, T.J.2
  • 71
    • 0027157232 scopus 로고
    • Comparison of diffusion studies of hydrocortisone between the Franz cell and the enhancer cell
    • Kumar P, Sanghvi P, Collins CC (1993) Comparison of diffusion studies of hydrocortisone between the Franz cell and the enhancer cell. Drug Dev Ind Pharm 19(13):1573–1585
    • (1993) Drug Dev Ind Pharm , vol.19 , Issue.13 , pp. 1573-1585
    • Kumar, P.1    Sanghvi, P.2    Collins, C.C.3
  • 72
    • 78650077732 scopus 로고    scopus 로고
    • Unacceptable side-effects associated with a hyperosmolar vaginal microbicide in a phase 1 trial
    • Lacey CJ, Woodhall S et al (2010) Unacceptable side-effects associated with a hyperosmolar vaginal microbicide in a phase 1 trial. Int J STD AIDS 21(10):714–717
    • (2010) Int J STD AIDS , vol.21 , Issue.10 , pp. 714-717
    • Lacey, C.J.1    Woodhall, S.2
  • 73
    • 77958150858 scopus 로고    scopus 로고
    • Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro
    • Lai BE, Geonnotti AR et al (2010) Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro. Antiviral Res 88(2):143–151
    • (2010) Antiviral Res , vol.88 , Issue.2 , pp. 143-151
    • Lai, B.E.1    Geonnotti, A.R.2
  • 74
    • 28644443338 scopus 로고    scopus 로고
    • In vitro non-viral gene delivery with nanofibrous scaffolds
    • Liang D, Luu YK et al (2005) In vitro non-viral gene delivery with nanofibrous scaffolds. Nucleic Acids Res 33(19):e170
    • (2005) Nucleic Acids Res , vol.33 , Issue.19
    • Liang, D.1    Luu, Y.K.2
  • 75
    • 0015845023 scopus 로고
    • C-film: A new vaginal contraceptive
    • Lichtman AS, Davajan V et al (1973) C-film: a new vaginal contraceptive. Contraception 8(4):291–297
    • (1973) Contraception , vol.8 , Issue.4 , pp. 291-297
    • Lichtman, A.S.1    Davajan, V.2
  • 76
    • 84858984112 scopus 로고    scopus 로고
    • Ethylene vinyl acetate intravaginal rings for the simultaneous delivery of the antiretroviral UC781 and contraceptive levonorgestrel
    • Loxley A, Mitchnick M et al (2011) Ethylene vinyl acetate intravaginal rings for the simultaneous delivery of the antiretroviral UC781 and contraceptive levonorgestrel. Drug Deliv Transl Res 1(3):247–255
    • (2011) Drug Deliv Transl Res , vol.1 , Issue.3 , pp. 247-255
    • Loxley, A.1    Mitchnick, M.2
  • 77
    • 28744457674 scopus 로고    scopus 로고
    • Controlled release of heparin from poly(epsiloncaprolactone) electrospun fibers
    • Luong-Van E, Grondahl L et al (2006) Controlled release of heparin from poly(epsiloncaprolactone) electrospun fibers. Biomaterials 27(9):2042–2050
    • (2006) Biomaterials , vol.27 , Issue.9 , pp. 2042-2050
    • Luong-Van, E.1    Grondahl, L.2
  • 78
    • 0000289081 scopus 로고
    • On the absorption of drugs and poisons through the vagina
    • Macht DI (1918) On the absorption of drugs and poisons through the vagina. J Pharmacol Exp Ther 10:509–522
    • (1918) J Pharmacol Exp Ther , vol.10 , pp. 509-522
    • Macht, D.I.1
  • 79
    • 78549244404 scopus 로고    scopus 로고
    • Design of a semisolid vaginal microbicide gel by relating composition to properties and performance
    • Mahalingam A, Smith E et al (2010) Design of a semisolid vaginal microbicide gel by relating composition to properties and performance. Pharm Res 27(11):2478–2491
    • (2010) Pharm Res , vol.27 , Issue.11 , pp. 2478-2491
    • Mahalingam, A.1    Smith, E.2
  • 80
    • 79953196872 scopus 로고    scopus 로고
    • Vaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1
    • Mahalingam A, Simmons AP et al (2011) Vaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1. Antimicrob Agents Chemother 55(4):1650–1660
    • (2011) Antimicrob Agents Chemother , vol.55 , Issue.4 , pp. 1650-1660
    • Mahalingam, A.1    Simmons, A.P.2
  • 81
    • 84921641962 scopus 로고    scopus 로고
    • A dapivirine releasing contraceptive diaphragm
    • Sydney, Australia
    • Major I, Boyd P et al (2012) A dapivirine releasing contraceptive diaphragm. Microbicides 2012, Sydney, Australia.
    • (2012) Microbicides , pp. 2012
    • Major, I.1    Boyd, P.2
  • 82
    • 78650827226 scopus 로고    scopus 로고
    • Development of a microbicide-releasing diaphragm as an HIV prevention strategy
    • Major I, Lowry D et al (2010) Development of a microbicide-releasing diaphragm as an HIV prevention strategy. Conf Proc IEEE Eng Med Biol Soc 2010:1089–1092
    • (2010) Conf Proc IEEE Eng Med Biol Soc , vol.2010 , pp. 1089-1092
    • Major, I.1    Lowry, D.2
  • 83
    • 78649398535 scopus 로고    scopus 로고
    • Advances in microbicide vaginal rings
    • Malcolm RK, Edwards KL et al (2010) Advances in microbicide vaginal rings. Antiviral Res 88(Suppl 1):S30–39
    • (2010) Antiviral Res , vol.88 , pp. S30-S39
    • Malcolm, R.K.1    Edwards, K.L.2
  • 84
    • 41249096760 scopus 로고    scopus 로고
    • Electrospun biodegradable nanofiber nonwovens for controlled release of proteins
    • Maretschek S, Greiner A et al (2008) Electrospun biodegradable nanofiber nonwovens for controlled release of proteins. J Control Release 127(2):180–187
    • (2008) J Control Release , vol.127 , Issue.2 , pp. 180-187
    • Maretschek, S.1    Greiner, A.2
  • 85
    • 0032710330 scopus 로고    scopus 로고
    • Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition
    • Martin HL, Richardson BA et al (1999) Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition. J Infect Dis 180(6):1863–1868
    • (1999) J Infect Dis , vol.180 , Issue.6 , pp. 1863-1868
    • Martin, H.L.1    Richardson, B.A.2
  • 86
    • 0030752641 scopus 로고    scopus 로고
    • An evaluation of the amount of nonoxynol-9 remaining in the vagina up to 4 h after insertion of a vaginal contraceptive film (VCF) containing 70 mg nonoxynol-9
    • Mauck CK, Allen S et al (1997a) An evaluation of the amount of nonoxynol-9 remaining in the vagina up to 4 h after insertion of a vaginal contraceptive film (VCF) containing 70 mg nonoxynol-9. Contraception 56(2):103–110
    • (1997) Contraception , vol.56 , Issue.2 , pp. 103-110
    • Mauck, C.K.1    Allen, S.2
  • 87
    • 0030770786 scopus 로고    scopus 로고
    • A phase I comparative study of contraceptive vaginal films containing benzalkonium chloride and nonoxynol-9
    • Mauck CK, Baker JM et al (1997b) A phase I comparative study of contraceptive vaginal films containing benzalkonium chloride and nonoxynol-9. Postcoital testing and colposcopy. Contraception 56(2):89–96
    • (1997) Postcoital testing and colposcopy. Contraception , vol.56 , Issue.2 , pp. 89-96
    • Mauck, C.K.1    Baker, J.M.2
  • 88
    • 0030768422 scopus 로고    scopus 로고
    • A phase I comparative study of three contraceptive vaginal films containing nonoxynol-9
    • Mauck CK, Baker JM et al (1997c) A phase I comparative study of three contraceptive vaginal films containing nonoxynol-9. Postcoital testing and colposcopy. Contraception 56(2):97–102
    • (1997) Postcoital testing and colposcopy. Contraception , vol.56 , Issue.2 , pp. 97-102
    • Mauck, C.K.1    Baker, J.M.2
  • 89
    • 70349959776 scopus 로고    scopus 로고
    • Engineering on the straight and narrow: The mechanics of nanofibrous assemblies for fiber-reinforced tissue regeneration
    • Mauck RL, Baker BM et al (2009) Engineering on the straight and narrow: the mechanics of nanofibrous assemblies for fiber-reinforced tissue regeneration. Tissue Eng Part B Rev 15(2):171–193
    • (2009) Tissue Eng Part B Rev , vol.15 , Issue.2 , pp. 171-193
    • Mauck, R.L.1    Baker, B.M.2
  • 90
    • 33645422725 scopus 로고    scopus 로고
    • Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women
    • Mayer KH, Maslankowski LA et al (2006) Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women. AIDS 20(4):543–551
    • (2006) AIDS , vol.20 , Issue.4 , pp. 543-551
    • Mayer, K.H.1    Maslankowski, L.A.2
  • 91
    • 84875746052 scopus 로고    scopus 로고
    • A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007)
    • McGowan I, Hoesley C et al (2013) A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007). PLoS One 8(4):e60147
    • (2013) PLoS One , vol.8 , Issue.4
    • McGowan, I.1    Hoesley, C.2
  • 92
    • 77249145280 scopus 로고    scopus 로고
    • Advances in the development of microbicides for the prevention of HIV infection
    • Minces LR, McGowan I (2010) Advances in the development of microbicides for the prevention of HIV infection. Curr Infect Dis Rep 12(1):56–62
    • (2010) Curr Infect Dis Rep , vol.12 , Issue.1 , pp. 56-62
    • Minces, L.R.1    McGowan, I.2
  • 93
    • 78349239340 scopus 로고    scopus 로고
    • Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse
    • Moench TR, Mumper RJ et al (2010) Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse. BMC Infect Dis 10:331
    • (2010) BMC Infect Dis , vol.10 , pp. 331
    • Moench, T.R.1    Mumper, R.J.2
  • 94
    • 78649407259 scopus 로고    scopus 로고
    • Clinical evaluation of microbicide formulations
    • Morrow KM, Hendrix C (2010) Clinical evaluation of microbicide formulations. Antiviral Res 88(Suppl 1):S40–46
    • (2010) Antiviral Res , vol.88 , pp. S40-S46
    • Morrow, K.M.1    Hendrix, C.2
  • 95
    • 84856071435 scopus 로고    scopus 로고
    • Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring
    • Moss JA, Malone AM et al (2012) Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring. Antimicrob Agents Chemother 56(2):875–882
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.2 , pp. 875-882
    • Moss, J.A.1    Malone, A.M.2
  • 96
    • 68049121905 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women
    • Nel A, Smythe S et al (2009a) Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women. J Acquir Immune Defic Syndr 51(4):416–423
    • (2009) J Acquir Immune Defic Syndr , vol.51 , Issue.4 , pp. 416-423
    • Nel, A.1    Smythe, S.2
  • 97
    • 68649117176 scopus 로고    scopus 로고
    • Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women
    • Nel AM, Coplan P et al (2009b) Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women. AIDS 23(12):1531–1538
    • (2009) AIDS , vol.23 , Issue.12 , pp. 1531-1538
    • Nel, A.M.1    Coplan, P.2
  • 98
    • 78649266105 scopus 로고    scopus 로고
    • Pharmacokinetic assessment of dapivirine vaginal microbicide gel in healthy, HIV-negative women
    • Nel AM, Coplan P et al (2010a) Pharmacokinetic assessment of dapivirine vaginal microbicide gel in healthy, HIV-negative women. AIDS Res Hum Retroviruses 26(11):1181–1190
    • (2010) AIDS Res Hum Retroviruses , vol.26 , Issue.11 , pp. 1181-1190
    • Nel, A.M.1    Coplan, P.2
  • 99
    • 77957323094 scopus 로고    scopus 로고
    • Pharmacokinetics of 2 dapivirine vaginal microbicide gels and their safety vs. Hydroxyethyl cellulose-based universal placebo gel
    • Nel AM, Smythe SC et al (2010b) Pharmacokinetics of 2 dapivirine vaginal microbicide gels and their safety vs. Hydroxyethyl cellulose-based universal placebo gel. J Acquir Immune Defic Syndr 55(2):161–169
    • (2010) J Acquir Immune Defic Syndr , vol.55 , Issue.2 , pp. 161-169
    • Nel, A.M.1    Smythe, S.C.2
  • 100
    • 80051758346 scopus 로고    scopus 로고
    • Acceptability of vaginal film, soft-gel capsule, and tablet as potential microbicide delivery methods among African women
    • Nel AM, Mitchnick LB et al (2011) Acceptability of vaginal film, soft-gel capsule, and tablet as potential microbicide delivery methods among African women. J Womens Health (Larchmt) 20(8):1207–1214
    • (2011) J Womens Health (Larchmt) , vol.20 , Issue.8 , pp. 1207-1214
    • Nel, A.M.1    Mitchnick, L.B.2
  • 101
    • 34547741003 scopus 로고    scopus 로고
    • Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering
    • Nerurkar NL, Elliott DM et al (2007) Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering. J Orthop Res 25(8):1018–1028
    • (2007) J Orthop Res , vol.25 , Issue.8 , pp. 1018-1028
    • Nerurkar, N.L.1    Elliott, D.M.2
  • 102
    • 0032807887 scopus 로고    scopus 로고
    • Design of a ‘‘microbicide’’ for prevention of sexually transmitted diseases using ‘‘inactive’’ pharmaceutical excipients
    • Neurath AR, Strick N et al (1999) Design of a ‘‘microbicide’’ for prevention of sexually transmitted diseases using ‘‘inactive’’ pharmaceutical excipients. Biologicals 27(1):11–21
    • (1999) Biologicals , vol.27 , Issue.1 , pp. 11-21
    • Neurath, A.R.1    Strick, N.2
  • 103
    • 2942627489 scopus 로고    scopus 로고
    • Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120
    • Neurath AR, Strick N et al (2001) Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120. BMC Infect Dis 1:17
    • (2001) BMC Infect Dis , vol.1 , pp. 17
    • Neurath, A.R.1    Strick, N.2
  • 104
    • 2442642818 scopus 로고    scopus 로고
    • Water dispersible microbicidal cellulose acetate phthalate film
    • Neurath AR, Strick N et al (2003) Water dispersible microbicidal cellulose acetate phthalate film. BMC Infect Dis 3:27
    • (2003) BMC Infect Dis , vol.3 , pp. 27
    • Neurath, A.R.1    Strick, N.2
  • 105
    • 0037369681 scopus 로고    scopus 로고
    • The combined contraceptive vaginal ring, NuvaRing: An international study of user acceptability
    • Novak A, de la Loge C et al (2003) The combined contraceptive vaginal ring, NuvaRing: an international study of user acceptability. Contraception 67(3):187–194
    • (2003) Contraception , vol.67 , Issue.3 , pp. 187-194
    • Novak, A.1    De La Loge, C.2
  • 107
    • 77950339867 scopus 로고    scopus 로고
    • Time-programmed dual release formulation by multilayered drug-loaded nanofiber meshes
    • Okuda T, Tominaga K et al (2010) Time-programmed dual release formulation by multilayered drug-loaded nanofiber meshes. J Control Release 143(2):258–264
    • (2010) J Control Release , vol.143 , Issue.2 , pp. 258-264
    • Okuda, T.1    Tominaga, K.2
  • 108
    • 0037235124 scopus 로고    scopus 로고
    • Effect of temperature and pH on contraceptive gel viscosity
    • Owen DH, Peters JJ et al (2003) Effect of temperature and pH on contraceptive gel viscosity. Contraception 67(1):57–64
    • (2003) Contraception , vol.67 , Issue.1 , pp. 57-64
    • Owen, D.H.1    Peters, J.J.2
  • 109
    • 33745799503 scopus 로고    scopus 로고
    • Electrospinning of polymeric nanofibers for tissue engineering applications: A review
    • Pham Q, Sharma U et al (2006) Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng 12(5):1197–1211
    • (2006) Tissue Eng , vol.12 , Issue.5 , pp. 1197-1211
    • Pham, Q.1    Sharma, U.2
  • 110
    • 0028564410 scopus 로고
    • Non-aqueous gel permeation chromatography of wheat starch in dimethylacetamide (DMAC) and LiCl: Extrusion-induced fragmentation
    • Politz ML, Timpa JD et al (1994) Non-aqueous gel permeation chromatography of wheat starch in dimethylacetamide (DMAC) and LiCl: extrusion-induced fragmentation. Carbohydr Polym 24:91–99
    • (1994) Carbohydr Polym , vol.24 , pp. 91-99
    • Politz, M.L.1    Timpa, J.D.2
  • 111
    • 33745242540 scopus 로고    scopus 로고
    • Comparative effects of a contraceptive vaginal ring delivering a nonandrogenic progestin and continuous ethinyl estradiol and a combined oral contraceptive containing levonorgestrel on hemostasis variables
    • Rad M, Kluft C et al (2006) Comparative effects of a contraceptive vaginal ring delivering a nonandrogenic progestin and continuous ethinyl estradiol and a combined oral contraceptive containing levonorgestrel on hemostasis variables. Am J Obstet Gynecol 195(1):72–77
    • (2006) Am J Obstet Gynecol , vol.195 , Issue.1 , pp. 72-77
    • Rad, M.1    Kluft, C.2
  • 112
    • 24344496912 scopus 로고    scopus 로고
    • Emerging drug targets for antiretroviral therapy
    • Reeves JD, Piefer AJ (2005) Emerging drug targets for antiretroviral therapy. Drugs 65(13):1747–1766
    • (2005) Drugs , vol.65 , Issue.13 , pp. 1747-1766
    • Reeves, J.D.1    Piefer, A.J.2
  • 114
    • 0032552228 scopus 로고    scopus 로고
    • A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases
    • Roddy RE, Zekeng L et al (1998) A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases. N Engl J Med 339(8):504–510
    • (1998) N Engl J Med , vol.339 , Issue.8 , pp. 504-510
    • Roddy, R.E.1    Zekeng, L.2
  • 115
    • 0035103518 scopus 로고    scopus 로고
    • Efficacy, tolerability and acceptability of a novel contraceptive vaginal ring releasing etonogestrel and ethinyl oestradiol
    • Roumen FJ, Apter D et al (2001) Efficacy, tolerability and acceptability of a novel contraceptive vaginal ring releasing etonogestrel and ethinyl oestradiol. Hum Reprod 16(3):469–475
    • (2001) Hum Reprod , vol.16 , Issue.3 , pp. 469-475
    • Roumen, F.J.1    Apter, D.2
  • 116
    • 0035010666 scopus 로고    scopus 로고
    • Thermoreversible gel formulations containing sodium lauryl sulfate or n-Lauroylsarcosine as potential topical microbicides against sexually transmitted diseases
    • Roy S, Gourde P et al (2001) Thermoreversible gel formulations containing sodium lauryl sulfate or n-Lauroylsarcosine as potential topical microbicides against sexually transmitted diseases. Antimicrob Agents Chemother 45(6):1671–1681
    • (2001) Antimicrob Agents Chemother , vol.45 , Issue.6 , pp. 1671-1681
    • Roy, S.1    Gourde, P.2
  • 117
    • 0344621700 scopus 로고    scopus 로고
    • Drug delivery system: Adding therapeutic and economic value to pharmacotherapy part 2
    • Sam AP, Fokkens JG (1997) Drug delivery system: adding therapeutic and economic value to pharmacotherapy part 2. Pharm Tech Eur 9:58–66
    • (1997) Pharm Tech Eur , vol.9 , pp. 58-66
    • Sam, A.P.1    Fokkens, J.G.2
  • 118
    • 52449109917 scopus 로고    scopus 로고
    • Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products
    • Sassi AB, Isaacs CE et al (2008) Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products. J Pharm Sci 97(8):3123–3139
    • (2008) J Pharm Sci , vol.97 , Issue.8 , pp. 3123-3139
    • Sassi, A.B.1    Isaacs, C.E.2
  • 119
    • 79955528232 scopus 로고    scopus 로고
    • Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product
    • Sassi AB, Cost MR et al (2011) Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product. Antimicrob Agents Chemother 55(5):2282–2289
    • (2011) Antimicrob Agents Chemother , vol.55 , Issue.5 , pp. 2282-2289
    • Sassi, A.B.1    Cost, M.R.2
  • 120
    • 67049101047 scopus 로고    scopus 로고
    • Sustained release of microbicides by newly engineered vaginal rings
    • Saxena BB, Han YA et al (2009) Sustained release of microbicides by newly engineered vaginal rings. AIDS 23(8):917–922
    • (2009) AIDS , vol.23 , Issue.8 , pp. 917-922
    • Saxena, B.B.1    Han, Y.A.2
  • 121
    • 48649101771 scopus 로고    scopus 로고
    • SILCS diaphragm: Postcoital testing of a new single-size contraceptive device
    • Schwartz JL, Ballagh SA et al (2008a) SILCS diaphragm: postcoital testing of a new single-size contraceptive device. Contraception 78(3):237–244
    • (2008) Contraception , vol.78 , Issue.3 , pp. 237-244
    • Schwartz, J.L.1    Ballagh, S.A.2
  • 122
    • 41149175595 scopus 로고    scopus 로고
    • A randomized six-day safety study of an antiretroviral microbicide candidate UC781, a non-nucleoside reverse transcriptase inhibitor
    • Schwartz JL, Kovalevsky G et al (2008b) A randomized six-day safety study of an antiretroviral microbicide candidate UC781, a non-nucleoside reverse transcriptase inhibitor. Sex Transm Dis 35(4):414–419
    • (2008) Sex Transm Dis , vol.35 , Issue.4 , pp. 414-419
    • Schwartz, J.L.1    Kovalevsky, G.2
  • 123
    • 0031958859 scopus 로고    scopus 로고
    • Drug-delivery products and the Zydis fast-dissolving dosage form
    • Seager H (1998) Drug-delivery products and the Zydis fast-dissolving dosage form. J Pharm Pharmacol 50(4):375–382
    • (1998) J Pharm Pharmacol , vol.50 , Issue.4 , pp. 375-382
    • Seager, H.1
  • 124
    • 84921641961 scopus 로고    scopus 로고
    • What is the STD-HIV connection? Accessed June 2000
    • Seattle King County Department of Public Health (2000) What is the STD-HIV connection? Accessed June 2000. http://www.metrokc.gov/health/apu/healthed/Powr/HIV_STD/sld003.htm
    • (2000)
  • 125
    • 0028870099 scopus 로고
    • Induction of labor utilizing vaginal vs. intracervical prostaglandin E2
    • Seeras RC (1995) Induction of labor utilizing vaginal vs. intracervical prostaglandin E2. Int J Gynaecol Obstet 48(2):163–167
    • (1995) Int J Gynaecol Obstet , vol.48 , Issue.2 , pp. 163-167
    • Seeras, R.C.1
  • 126
    • 0028910796 scopus 로고
    • Induction of labor using prostaglandin E2 (PGE2) vaginal gel in triacetin base. An efficacy study comparing two dosage regimens
    • Seeras RC, Olatunbosun OA et al (1995) Induction of labor using prostaglandin E2 (PGE2) vaginal gel in triacetin base. An efficacy study comparing two dosage regimens. Clin Exp Obstet Gynecol 22(2):105–110
    • (1995) Clin Exp Obstet Gynecol , vol.22 , Issue.2 , pp. 105-110
    • Seeras, R.C.1    Olatunbosun, O.A.2
  • 127
    • 0024340376 scopus 로고
    • Determination of in vitro drug release from hydrocortisone creams
    • Shah VP, Elkins J et al (1989) Determination of in vitro drug release from hydrocortisone creams. Int J Pharm 53(1):53–59
    • (1989) Int J Pharm , vol.53 , Issue.1 , pp. 53-59
    • Shah, V.P.1    Elkins, J.2
  • 128
    • 0141800053 scopus 로고    scopus 로고
    • FIP/AAPS guidelines to dissolution/in vitro release testing of novel/special dosage forms
    • Siewert M, Dressman J et al (2003) FIP/AAPS guidelines to dissolution/in vitro release testing of novel/special dosage forms. AAPS PharmSciTech 4(1):E7
    • (2003) AAPS PharmSciTech , vol.4 , Issue.1
    • Siewert, M.1    Dressman, J.2
  • 129
    • 57049091723 scopus 로고    scopus 로고
    • Efficacy of Carraguard for prevention of HIV infection in women in South Africa: A randomised, double-blind, placebo-controlled trial
    • Skoler-Karpoff S, Ramjee G et al (2008) Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial. Lancet 372(9654):1977–1987
    • (2008) Lancet , vol.372 , Issue.9654 , pp. 1977-1987
    • Skoler-Karpoff, S.1    Ramjee, G.2
  • 130
    • 5144234094 scopus 로고    scopus 로고
    • Mucosal drug delivery: Membranes, methodologies, and applications
    • Song Y, Wang Y et al (2004) Mucosal drug delivery: membranes, methodologies, and applications. Crit Rev Ther Drug Carrier Syst 21(3):195–256
    • (2004) Crit Rev Ther Drug Carrier Syst , vol.21 , Issue.3 , pp. 195-256
    • Song, Y.1    Wang, Y.2
  • 131
    • 27644501985 scopus 로고    scopus 로고
    • Controlled fabrication of a biological vascular substitute
    • Stitzel J, Liu J et al (2006) Controlled fabrication of a biological vascular substitute. Biomaterials 27(7):1088–1094
    • (2006) Biomaterials , vol.27 , Issue.7 , pp. 1088-1094
    • Stitzel, J.1    Liu, J.2
  • 132
    • 79952303706 scopus 로고    scopus 로고
    • Development and characterization of bioadhesive vaginal films of clotrimazole for vaginal candidiasis
    • Sudeendra B, Umme H et al (2010) Development and characterization of bioadhesive vaginal films of clotrimazole for vaginal candidiasis. Acta Pharmaceutica Sciencia 52:417–426
    • (2010) Acta Pharmaceutica Sciencia , vol.52 , pp. 417-426
    • Sudeendra, B.1    Umme, H.2
  • 133
    • 0024100474 scopus 로고
    • Biostability of polyurethane elastomers: A critical review
    • Szycher M (1988) Biostability of polyurethane elastomers: a critical review. J Biomater Appl 3(2):297–402
    • (1988) J Biomater Appl , vol.3 , Issue.2 , pp. 297-402
    • Szycher, M.1
  • 134
    • 33646200711 scopus 로고    scopus 로고
    • Drug-loaded electrospun mats of poly(vinyl alcohol) fibres and their release characteristics of four model drugs
    • Taepaiboon P, Rungsardthong U et al (2006) Drug-loaded electrospun mats of poly(vinyl alcohol) fibres and their release characteristics of four model drugs. Nanotechnology 17(9):2317–2329
    • (2006) Nanotechnology , vol.17 , Issue.9 , pp. 2317-2329
    • Taepaiboon, P.1    Rungsardthong, U.2
  • 135
    • 0029866440 scopus 로고    scopus 로고
    • The effects of ageing on the rheological, dielectric and mucoadhesive properties of poly(acrylic acid) gel systems
    • Tamburic S, Craig DQ (1996) The effects of ageing on the rheological, dielectric and mucoadhesive properties of poly(acrylic acid) gel systems. Pharm Res 13(2):279–283
    • (1996) Pharm Res , vol.13 , Issue.2 , pp. 279-283
    • Tamburic, S.1    Craig, D.Q.2
  • 136
    • 56749163373 scopus 로고    scopus 로고
    • Electrospinning of photocrosslinked and degradable fibrous scaffolds
    • Tan AR, Ifkovits JL et al (2008) Electrospinning of photocrosslinked and degradable fibrous scaffolds. J Biomed Mater Res A 87(4):1034–1043
    • (2008) J Biomed Mater Res A , vol.87 , Issue.4 , pp. 1034-1043
    • Tan, A.R.1    Ifkovits, J.L.2
  • 137
    • 48749086467 scopus 로고    scopus 로고
    • Enhancement of HIV infection by cellulose sulfate
    • Tao W, Richards C et al (2008) Enhancement of HIV infection by cellulose sulfate. AIDS Res Hum Retroviruses 24(7):925–929
    • (2008) AIDS Res Hum Retroviruses , vol.24 , Issue.7 , pp. 925-929
    • Tao, W.1    Richards, C.2
  • 138
    • 0035444059 scopus 로고    scopus 로고
    • Electrostatic field-assisted alignment of electrospun nanofibres
    • Theron A, Zussman E et al (2001) Electrostatic field-assisted alignment of electrospun nanofibres. Nanotechnology 12:384–390
    • (2001) Nanotechnology , vol.12 , pp. 384-390
    • Theron, A.1    Zussman, E.2
  • 139
    • 0035698796 scopus 로고    scopus 로고
    • A new intravaginal device for stress incontinence in women
    • Thyssen H, Bidmead J et al (2001) A new intravaginal device for stress incontinence in women. BJU Int 88(9):889–892
    • (2001) BJU Int , vol.88 , Issue.9 , pp. 889-892
    • Thyssen, H.1    Bidmead, J.2
  • 140
    • 33845239887 scopus 로고    scopus 로고
    • Biocompatibility of solid-dosage forms of anti-human immunodeficiency virus type 1 microbicides with the human cervicovaginal mucosa modeled ex vivo
    • Trifonova RT, Pasicznyk JM et al (2006) Biocompatibility of solid-dosage forms of anti-human immunodeficiency virus type 1 microbicides with the human cervicovaginal mucosa modeled ex vivo. Antimicrob Agents Chemother 50(12):4005–4010
    • (2006) Antimicrob Agents Chemother , vol.50 , Issue.12 , pp. 4005-4010
    • Trifonova, R.T.1    Pasicznyk, J.M.2
  • 141
    • 84856496679 scopus 로고    scopus 로고
    • Topical microbicides to prevent the transmission of HIV: Formulation gaps and challenges
    • Turpin JA (2011) Topical microbicides to prevent the transmission of HIV: formulation gaps and challenges. Drug Deliv Transl Res 1(3):194–200
    • (2011) Drug Deliv Transl Res , vol.1 , Issue.3 , pp. 194-200
    • Turpin, J.A.1
  • 142
    • 0037151321 scopus 로고    scopus 로고
    • Effect of supersaturation and crystallization phenomena on the release properties of a controlled release device based on EVA copolymer
    • van Laarhoven JA, Kruft MA et al (2002a) Effect of supersaturation and crystallization phenomena on the release properties of a controlled release device based on EVA copolymer. J Control Release 82(2–3):309–317
    • (2002) J Control Release , vol.82 , Issue.2-3 , pp. 309-317
    • Van Laarhoven, J.A.1    Kruft, M.A.2
  • 143
    • 0037203657 scopus 로고    scopus 로고
    • In vitro release properties of etonogestrel and ethinyl estradiol from a contraceptive vaginal ring
    • van Laarhoven JA, Kruft MA et al (2002b) In vitro release properties of etonogestrel and ethinyl estradiol from a contraceptive vaginal ring. Int J Pharm 232(1–2):163–173
    • (2002) Int J Pharm , vol.232 , Issue.1-2 , pp. 163-173
    • Van Laarhoven, J.A.1    Kruft, M.A.2
  • 144
    • 77954068718 scopus 로고    scopus 로고
    • Acceptability of UC781 gel as a rectal microbicide among HIV-uninfected women and men
    • Ventuneac A, Carballo-Dieguez A et al (2010) Acceptability of UC781 gel as a rectal microbicide among HIV-uninfected women and men. AIDS Behav 14(3):618–628
    • (2010) AIDS Behav , vol.14 , Issue.3 , pp. 618-628
    • Ventuneac, A.1    Carballo-Dieguez, A.2
  • 145
    • 0034306493 scopus 로고    scopus 로고
    • The scope and potential of vaginal drug delivery
    • Vermani K, Garg S (2000) The scope and potential of vaginal drug delivery. Pharm Sci Technolo Today 3(10):359–364
    • (2000) Pharm Sci Technolo Today , vol.3 , Issue.10 , pp. 359-364
    • Vermani, K.1    Garg, S.2
  • 146
    • 0002139122 scopus 로고
    • Zydis-a novel, fast dissolving dosage form
    • Virley P, Yarwood R (1990) Zydis-a novel, fast dissolving dosage form. Manufact Chemist 61:36–37
    • (1990) Manufact Chemist , vol.61 , pp. 36-37
    • Virley, P.1    Yarwood, R.2
  • 147
    • 65549132388 scopus 로고    scopus 로고
    • Dissolvable films: Dissolvable films for flexible product format in drug delivery
    • Accessed
    • Vondrak B, Barnhart S (2008) Dissolvable films: dissolvable films for flexible product format in drug delivery. Pharm Technol. Accessed http://www.pharmtech.com/pharmtech/Article/Dissolvable-Films-Dissolvable-Films-for-Flexible-P/ArticleStandard/Article/detail/505380
    • (2008) Pharm Technol
    • Vondrak, B.1    Barnhart, S.2
  • 148
    • 73849103173 scopus 로고    scopus 로고
    • Effect of experimental parameters on the formation of chitosan- Poly(acrylic acid) nanofibrous scaffolds and evaluation of their potential application as DNA carrier
    • Wang J, Chen C et al (2010) Effect of experimental parameters on the formation of chitosan- Poly(acrylic acid) nanofibrous scaffolds and evaluation of their potential application as DNA carrier. J Appl Polym Sci 155(1769):1769–1780
    • (2010) J Appl Polym Sci , vol.155 , Issue.1769 , pp. 1769-1780
    • Wang, J.1    Chen, C.2
  • 149
    • 22144454301 scopus 로고    scopus 로고
    • The development of vaginal microbicides for the prevention of HIV transmission
    • Weber J, Desai K et al (2005) The development of vaginal microbicides for the prevention of HIV transmission. PLoS Med 2(5):e142
    • (2005) PLoS Med , vol.2 , Issue.5
    • Weber, J.1    Desai, K.2
  • 150
    • 33645776259 scopus 로고    scopus 로고
    • Nano-fibrous scaffold for controlled delivery of recombinant human PDGF-BB
    • Wei G, Jin Q et al (2006) Nano-fibrous scaffold for controlled delivery of recombinant human PDGF-BB. J Control Release 112(1):103–110
    • (2006) J Control Release , vol.112 , Issue.1 , pp. 103-110
    • Wei, G.1    Jin, Q.2
  • 151
    • 0011757065 scopus 로고
    • Hydrophilic gels for biological use
    • Wichterle O, Lim D (1960) Hydrophilic gels for biological use. Nature 185(4706):117–118
    • (1960) Nature , vol.185 , Issue.4706 , pp. 117-118
    • Wichterle, O.1    Lim, D.2
  • 152
    • 0032827796 scopus 로고    scopus 로고
    • Design of an intravaginal ring for the controlled delivery of 17 beta-estradiol as its 3-acetate ester
    • Woolfson A, Elliott G et al (1999) Design of an intravaginal ring for the controlled delivery of 17 beta-estradiol as its 3-acetate ester. J Control Release 61(3):319–328
    • (1999) J Control Release , vol.61 , Issue.3 , pp. 319-328
    • Woolfson, A.1    Elliott, G.2
  • 153
    • 65549098898 scopus 로고    scopus 로고
    • Characterization of cyclodextrin inclusion complexes of the anti-HIV non-nucleoside reverse transcriptase inhibitor UC781
    • Yang H, Parniak MA et al (2008) Characterization of cyclodextrin inclusion complexes of the anti-HIV non-nucleoside reverse transcriptase inhibitor UC781. AAPS J 10(4):606–613
    • (2008) AAPS J , vol.10 , Issue.4 , pp. 606-613
    • Yang, H.1    Parniak, M.A.2
  • 154
    • 31144448147 scopus 로고    scopus 로고
    • The physicodynamic properties of mucoadhesive polymeric films developed as female controlled drug delivery system
    • Yoo JW, Dharmala K et al (2006) The physicodynamic properties of mucoadhesive polymeric films developed as female controlled drug delivery system. Int J Pharm 309(1–2):139–145
    • (2006) Int J Pharm , vol.309 , Issue.1-2 , pp. 139-145
    • Yoo, J.W.1    Dharmala, K.2
  • 155
    • 67349181056 scopus 로고    scopus 로고
    • In vivo evaluation of vaginal films for mucosal delivery of nitric oxide
    • Yoo JW, Acharya G et al (2009) In vivo evaluation of vaginal films for mucosal delivery of nitric oxide. Biomaterials 30(23–24):3978–3985
    • (2009) Biomaterials , vol.30 , Issue.23-24 , pp. 3978-3985
    • Yoo, J.W.1    Acharya, G.2
  • 157
    • 33646354615 scopus 로고    scopus 로고
    • Coaxial electrospinning of (fluorescein isothiocyanateconjugated bovine serum albumin)-encapsulated poly(epsilon-caprolactone) nanofibers for sustained release
    • Microbicides, Sydney, Australia Zhang YZ, Wang X et al (2006) Coaxial electrospinning of (fluorescein isothiocyanateconjugated bovine serum albumin)-encapsulated poly(epsilon-caprolactone) nanofibers for sustained release. Biomacromolecules 7(4):1049–1057
    • (2006) Biomacromolecules , vol.7 , Issue.4 , pp. 1049-1057
    • Microbicides, S.1    Australia Zhang, Y.Z.2    Wang, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.