In vivo evaluation of vaginal films for mucosal delivery of nitric oxide

Biomaterials

Volumn 30, Issue 23-24, 2009, Pages 3978-3985

  Yoo, Jin Wook ^a   Acharya, Gayathri ^a   Lee, Chi H ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Female sexual arousal disorder; Nitric oxide; NO releasing vaginal film; Vagina blood flow

Indexed keywords

ADVANCED TREATMENT; BLOOD PERFUSION; CYTOTOXIC EFFECTS; DRYING METHODS; FEMALE SEXUAL AROUSAL DISORDER; FIRST ORDER KINETICS; IN-VITRO; IN-VIVO; LOADING EFFICIENCY; MUCOSAL DELIVERY; NO DONOR; NO-RELEASING VAGINAL FILM; PHARMACOLOGICAL ACTIVITY; POLYMERIC FILMS; RAT MODEL; RELEASE PROFILES; S-NITROSOGLUTATHIONE; SIGNALING PATHWAYS; VAGINA BLOOD FLOW;

BLOOD; HEMODYNAMICS; MECHANICAL PROPERTIES; NITRIC OXIDE;

OXIDE FILMS;

CARBOMER; CYCLIC GMP; HYDROXYPROPYLMETHYLCELLULOSE; MACROGOL; METHYLCELLULOSE; NITRIC OXIDE; S NITROSOGLUTATHIONE;

ANIMAL EXPERIMENT; ARTICLE; BIOFILM; CELL TYPE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; FEMALE; FEMALE SEXUAL DYSFUNCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MORPHOLOGY; MUCOADHESION; NONHUMAN; PERFUSION; PRIORITY JOURNAL; RAT; SEXUAL AROUSAL DISORDER; VAGINA CELL; VAGINAL FILM;

ANIMALS; CELL LINE; DRUG CARRIERS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, SCANNING; MUCOUS MEMBRANE; NITRIC OXIDE DONORS; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; VAGINA;

RATTUS;

EID: 67349181056     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.04.004     Document Type: Article

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