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Volumn 13, Issue 4, 2008, Pages 339-350

Update on nonoxynol-9 as vaginal spermicide

Author keywords

Cervical mucus; Contraceptive; Nonoxynol 9; Semen; Spermicide

Indexed keywords

ADVANTAGE 24; CELECOXIB; GYNOLL; INDOMETACIN; NONOXINOL 9; POVIDONE; PROPRANOLOL DERIVATIVE; TODAY; UNCLASSIFIED DRUG; VCF; CONTRACEPTIVE AGENT; NON PRESCRIPTION DRUG; NONOXINOL; SPERMICIDAL AGENT; SURFACTANT;

EID: 64749099593     PISSN: 13625187     EISSN: 14730782     Source Type: Journal    
DOI: 10.1080/13625180802263515     Document Type: Review
Times cited : (24)

References (82)
  • 1
    • 0016657917 scopus 로고
    • Solubilization of membranes by detergents
    • Helenius A, Simons K. Solubilization of membranes by detergents. Biochim Biophys Acta 1975; 415:29-79.
    • (1975) Biochim Biophys Acta , vol.415 , pp. 29-79
    • Helenius, A.1    Simons, K.2
  • 2
    • 0018855313 scopus 로고
    • Studies of nonoxynol-9. III. Effect of fibroblasts and spermatozoa
    • Chapvil M, Ulreich JB, O'Dea K, et al. Studies of nonoxynol-9. III. Effect of fibroblasts and spermatozoa. Fertil Steril 1980;33:521-5.
    • (1980) Fertil Steril , vol.33 , pp. 521-525
    • Chapvil, M.1    Ulreich, J.B.2    O'Dea, K.3
  • 3
    • 0029091528 scopus 로고
    • Spermicidal activity-structure relationship of nonoxynol oligomers: Physicochemical basis
    • Yu K, Yie W. Spermicidal activity-structure relationship of nonoxynol oligomers: Physicochemical basis. Int J Pharm 1995;125:81-90.
    • (1995) Int J Pharm , vol.125 , pp. 81-90
    • Yu, K.1    Yie, W.2
  • 4
    • 0025865490 scopus 로고
    • Solubilization and in vitro spermicidal assessment of nonoxynol-9 and selected fractions using rabbit spermatozoa
    • Walter BA, Hawi AA, Zavos PM, Digensis GA. Solubilization and in vitro spermicidal assessment of nonoxynol-9 and selected fractions using rabbit spermatozoa. Pharm Res 1991;8:403-8.
    • (1991) Pharm Res , vol.8 , pp. 403-408
    • Walter, B.A.1    Hawi, A.A.2    Zavos, P.M.3    Digensis, G.A.4
  • 5
    • 0028832136 scopus 로고
    • Spermicidal activity of nonoxynol-9: Quantitative assessment using flow cytometry
    • Yu K, Bagdon RE, Yurkow EJ, Chien YW. Spermicidal activity of nonoxynol-9: quantitative assessment using flow cytometry. Drug Dev Indu Pharm 1995;21: 243-56.
    • (1995) Drug Dev Indu Pharm , vol.21 , pp. 243-256
    • Yu, K.1    Bagdon, R.E.2    Yurkow, E.J.3    Chien, Y.W.4
  • 6
    • 31944439679 scopus 로고    scopus 로고
    • In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: A retrospective analysis of results from five laboratories
    • Beer BE, Doncel GF, Krebs FC, et al. In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories. Antimicrob Agents Chemother 2006;50:713- 23.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 713-723
    • Beer, B.E.1    Doncel, G.F.2    Krebs, F.C.3
  • 7
    • 0026514158 scopus 로고
    • Vaginal spermicides: Some current concerns
    • Chantler E. Vaginal spermicides: some current concerns. Br J Fam Plann 1992;17:118-9.
    • (1992) Br J Fam Plann , vol.17 , pp. 118-119
    • Chantler, E.1
  • 8
    • 0001737437 scopus 로고
    • A practical method for testing the spermicidal action of chemical contraceptives
    • Sander F, Cramer S. A practical method for testing the spermicidal action of chemical contraceptives. Hum Fertil 1941;6:134-7.
    • (1941) Hum Fertil , vol.6 , pp. 134-137
    • Sander, F.1    Cramer, S.2
  • 9
    • 0015955855 scopus 로고
    • Special requirements for testing spermicides
    • McConnell RF. Special requirements for testing spermicides. Acta Endocrinol 1974;75:373-86.
    • (1974) Acta Endocrinol , vol.75 , pp. 373-386
    • McConnell, R.F.1
  • 10
    • 0037190597 scopus 로고    scopus 로고
    • Effectiveness of COL-1492, nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: A randomized clinical trial
    • Van Damme L, Ramjee G, Alary M, et al. Effectiveness of COL-1492, nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: A randomized clinical trial. Lancet 2002;360: 971-7.
    • (2002) Lancet , vol.360 , pp. 971-977
    • Van Damme, L.1    Ramjee, G.2    Alary, M.3
  • 11
    • 41949137339 scopus 로고    scopus 로고
    • Over-the-counter vaginal contraceptive and spermicide drug products containing nonoxynol-9; required labeling. Final rule
    • Over-the-counter vaginal contraceptive and spermicide drug products containing nonoxynol-9; required labeling. Final rule. Federal Register 2007;72: 71769-85.
    • (2007) Federal Register , vol.72 , pp. 71769-71785
  • 12
    • 0019420083 scopus 로고
    • Ultrastructure of human spermatozoa in the presence of the spermicide nonoxynol-9 and a vaginal contraceptive containing nonoxynol-9
    • Schill WB, Wolff HH. Ultrastructure of human spermatozoa in the presence of the spermicide nonoxynol-9 and a vaginal contraceptive containing nonoxynol-9. Andrologia 1981;13:42-9.
    • (1981) Andrologia , vol.13 , pp. 42-49
    • Schill, W.B.1    Wolff, H.H.2
  • 13
    • 0020622026 scopus 로고
    • Scanning electron microscopy of human spermatozoa after incubation with the spermicide nonoxynol-9
    • Wilborn WH, Hahn DW, McGuire JJ. Scanning electron microscopy of human spermatozoa after incubation with the spermicide nonoxynol-9. Fertil Steril 1983;39:717-9.
    • (1983) Fertil Steril , vol.39 , pp. 717-719
    • Wilborn, W.H.1    Hahn, D.W.2    McGuire, J.J.3
  • 14
    • 65249160315 scopus 로고    scopus 로고
    • Time dependent pattern of activity of the spermicide nonoxynol-9 on sperm qualitative characteristics
    • Zavos PM, Correa JR, Kaskar K, Zarmakoupis-Zavos PN. Time dependent pattern of activity of the spermicide nonoxynol-9 on sperm qualitative characteristics. Fertil Steril 2001;76(Suppl. 1):S263.
    • (2001) Fertil Steril , vol.76 , Issue.SUPPL. 1
    • Zavos, P.M.1    Correa, J.R.2    Kaskar, K.3    Zarmakoupis-Zavos, P.N.4
  • 15
    • 0002436289 scopus 로고
    • Micelle formation in aqueous and nonaqueous solutions
    • Schick M, ed, New York: Marcel Dekker
    • Becher P. Micelle formation in aqueous and nonaqueous solutions. In Schick M, ed. Nonionic surfactants. New York: Marcel Dekker, 1967:478- 515.
    • (1967) Nonionic surfactants , pp. 478-515
    • Becher, P.1
  • 17
    • 0343355658 scopus 로고
    • The micelle diffusion coefficient
    • DeGiorgio V, Corti M. The micelle diffusion coefficient. J Col1 Interf Sci 1984;101:289-91.
    • (1984) J Col1 Interf Sci , vol.101 , pp. 289-291
    • DeGiorgio, V.1    Corti, M.2
  • 18
    • 0021062009 scopus 로고
    • Liposomal membranes: XVIII. Interaction of spermicidal agents with liposomal membranes
    • Sunamoto J, Iwamoto K, Uesugi T, et al. Liposomal membranes: XVIII. Interaction of spermicidal agents with liposomal membranes. Chem Pharm Bull 1984;31:4230-5.
    • (1984) Chem Pharm Bull , vol.31 , pp. 4230-4235
    • Sunamoto, J.1    Iwamoto, K.2    Uesugi, T.3
  • 19
    • 0020523368 scopus 로고
    • Studies on the spermicidal activity of surfactants. 1. Correlation between spermicidal effect and physiochemical properties of p-menthanylphenyl polyoxyethylene (8.8) ether and related surfactants
    • Furuse K, Ishizeki C, Iwahara S. Studies on the spermicidal activity of surfactants. 1. Correlation between spermicidal effect and physiochemical properties of p-menthanylphenyl polyoxyethylene (8.8) ether and related surfactants. J Pharm Dyn 1983;6:359-72.
    • (1983) J Pharm Dyn , vol.6 , pp. 359-372
    • Furuse, K.1    Ishizeki, C.2    Iwahara, S.3
  • 20
    • 0029892687 scopus 로고    scopus 로고
    • Characterisation of in vitro spermicidal activity of chelating agent against human sperm
    • Lee CH, Anderson M, Chien YW. Characterisation of in vitro spermicidal activity of chelating agent against human sperm. J Pharm Sci 1996;85:649-54.
    • (1996) J Pharm Sci , vol.85 , pp. 649-654
    • Lee, C.H.1    Anderson, M.2    Chien, Y.W.3
  • 21
    • 0031958840 scopus 로고    scopus 로고
    • Diffusion of nonoxynol-9 into human semen in vitro
    • Chantler E, Gwanmesia IL, Bruce JM. Diffusion of nonoxynol-9 into human semen in vitro. Contraception 1998;57:111-5.
    • (1998) Contraception , vol.57 , pp. 111-115
    • Chantler, E.1    Gwanmesia, I.L.2    Bruce, J.M.3
  • 22
    • 0036669711 scopus 로고    scopus 로고
    • In vitro test to evaluate the interaction between synthetic cervical mucus and vaginal formulations
    • Burruano BT, Schnaare RL, Malamud D. In vitro test to evaluate the interaction between synthetic cervical mucus and vaginal formulations. Contraception 2002;66: 137-40.
    • (2002) Contraception , vol.66 , pp. 137-140
    • Burruano, B.T.1    Schnaare, R.L.2    Malamud, D.3
  • 23
    • 0015909406 scopus 로고
    • Relation of detergent HLB number to solubilization and stabilization of D-alanine carboxypeptidase from Bacillus subtilis membrane
    • Umbreit JN, Strominger JL. Relation of detergent HLB number to solubilization and stabilization of D-alanine carboxypeptidase from Bacillus subtilis membrane. Proc Natl Acad Sci 1973;71:2997-3001.
    • (1973) Proc Natl Acad Sci , vol.71 , pp. 2997-3001
    • Umbreit, J.N.1    Strominger, J.L.2
  • 24
    • 65249146725 scopus 로고    scopus 로고
    • Christian M. Cosmetic ingredient review: Final report on the safety assessment of nonoxynols -2, -4, -8, -9, -10, -12, -14, 15, 30, -40 and -50. J Am Coll Toxicol 1983;2:35.
    • Christian M. Cosmetic ingredient review: Final report on the safety assessment of nonoxynols -2, -4, -8, -9, -10, -12, -14, 15, 30, -40 and -50. J Am Coll Toxicol 1983;2:35.
  • 26
    • 65249108270 scopus 로고    scopus 로고
    • Photodegradation of nonoxynol-9 in aqueous media. Studies of its in vitro phototoxicity
    • Canudas N, Rivas C. Photodegradation of nonoxynol-9 in aqueous media. Studies of its in vitro phototoxicity. Internet J Sci Biol Chem 1997. http://www.netscijournal. com/97v4/97017/index.htm
    • (1997) Internet J Sci Biol Chem
    • Canudas, N.1    Rivas, C.2
  • 27
    • 7344246554 scopus 로고    scopus 로고
    • Use of nonoxynol-9 and changes in vaginal lactobacilli
    • Richardson BA, Martin HL, Stevens CE, et al. Use of nonoxynol-9 and changes in vaginal lactobacilli. J Infect Dis 1998;178:441-5.
    • (1998) J Infect Dis , vol.178 , pp. 441-445
    • Richardson, B.A.1    Martin, H.L.2    Stevens, C.E.3
  • 28
    • 29144532580 scopus 로고    scopus 로고
    • Lactobacillus species isolated from the vagina: Identification, hydrogen peroxide production and nonoxynol-9 resistance
    • Pascual LM, Daniele MB, Pa'jaro C, Barberis L. Lactobacillus species isolated from the vagina: Identification, hydrogen peroxide production and nonoxynol-9 resistance. Contraception 2006;73:78-81.
    • (2006) Contraception , vol.73 , pp. 78-81
    • Pascual, L.M.1    Daniele, M.B.2    Pa'jaro, C.3    Barberis, L.4
  • 29
    • 39149106104 scopus 로고    scopus 로고
    • The effects of spermicides containing nonoxynol-9 on cervical cytology
    • Halpern V, Rountree W, Raymond EG, Law M. The effects of spermicides containing nonoxynol-9 on cervical cytology. Contraception 2008;77:191-4.
    • (2008) Contraception , vol.77 , pp. 191-194
    • Halpern, V.1    Rountree, W.2    Raymond, E.G.3    Law, M.4
  • 30
    • 13544267591 scopus 로고    scopus 로고
    • The effect of nonoxynol-9 on human endometrium
    • Jain JK, Li A, Minoo P, et al. The effect of nonoxynol-9 on human endometrium. Contraception 2005;71:137-42.
    • (2005) Contraception , vol.71 , pp. 137-142
    • Jain, J.K.1    Li, A.2    Minoo, P.3
  • 31
    • 0031924987 scopus 로고    scopus 로고
    • Effect on normal vaginal flora of three intravaginal microbicidal agents potentially active against human immunodeficiency virus type 1
    • Rosenstein IJ, Stafford MK, Kitchen VS, et al. Effect on normal vaginal flora of three intravaginal microbicidal agents potentially active against human immunodeficiency virus type 1. J Infect Dis 1998;177:1386-90.
    • (1998) J Infect Dis , vol.177 , pp. 1386-1390
    • Rosenstein, I.J.1    Stafford, M.K.2    Kitchen, V.S.3
  • 33
    • 33748936111 scopus 로고    scopus 로고
    • The impact of use of COL-1492, a nonoxynol-9 vaginal gel, on the presence of cervical human papillomavirus in female sex workers
    • Marais D, Cararra H, Kay P, et al. The impact of use of COL-1492, a nonoxynol-9 vaginal gel, on the presence of cervical human papillomavirus in female sex workers. Virus Res 2006;121:220-2.
    • (2006) Virus Res , vol.121 , pp. 220-222
    • Marais, D.1    Cararra, H.2    Kay, P.3
  • 34
    • 0020073908 scopus 로고
    • Teratology study of intravaginally administered nonoxynol-9 containing contraceptive cream in rats
    • Abrutyn D, McKenzie BE, Nadaskay N. Teratology study of intravaginally administered nonoxynol-9 containing contraceptive cream in rats. Fertil Steril 1982;37:113-7.
    • (1982) Fertil Steril , vol.37 , pp. 113-117
    • Abrutyn, D.1    McKenzie, B.E.2    Nadaskay, N.3
  • 35
    • 0032935520 scopus 로고    scopus 로고
    • Synthesis, characterization and preclinical formulation of a dualaction phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI- 07) with potent anti-HIV and spermicidal activities
    • D'Cruz OJ, Shin MJ, Yiv SH, et al. Synthesis, characterization and preclinical formulation of a dualaction phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI- 07) with potent anti-HIV and spermicidal activities. Mol Hum Reprod 1999;5:421- 32.
    • (1999) Mol Hum Reprod , vol.5 , pp. 421-432
    • D'Cruz, O.J.1    Shin, M.J.2    Yiv, S.H.3
  • 36
    • 0026196420 scopus 로고
    • The effects of frequent nonoxynol-9 use on the vaginal and cervical mucosa
    • Niruthisard S, Roddy RE, Chutivongse S. The effects of frequent nonoxynol-9 use on the vaginal and cervical mucosa. Sex Transm Dis 1991;18:176-9.
    • (1991) Sex Transm Dis , vol.18 , pp. 176-179
    • Niruthisard, S.1    Roddy, R.E.2    Chutivongse, S.3
  • 37
    • 0026576056 scopus 로고
    • The toxicity and local effects of the spermicide nonoxynol-9
    • Rekart ML. The toxicity and local effects of the spermicide nonoxynol-9. J Acquir Immune Defic Syndr 1992;5:425-7.
    • (1992) J Acquir Immune Defic Syndr , vol.5 , pp. 425-427
    • Rekart, M.L.1
  • 38
    • 0028901558 scopus 로고
    • Nonoxynol-9 use, genital ulcers and HIV infection in a cohort of sex workers
    • Weir SS, Roddy RE, Zekeng L, Feldblum PJ. Nonoxynol-9 use, genital ulcers and HIV infection in a cohort of sex workers. Genitourin Med 1995;71:78- 81.
    • (1995) Genitourin Med , vol.71 , pp. 78-81
    • Weir, S.S.1    Roddy, R.E.2    Zekeng, L.3    Feldblum, P.J.4
  • 39
    • 0037029112 scopus 로고    scopus 로고
    • Effect of N-9 gel in urogenital gonorrhea and chlamydial infection: A randomized controlled trial
    • Roddy RE, Zekeng L, Ryan KA, et al. Effect of N-9 gel in urogenital gonorrhea and chlamydial infection: A randomized controlled trial. JAMA 2002;287:1117-22.
    • (2002) JAMA , vol.287 , pp. 1117-1122
    • Roddy, R.E.1    Zekeng, L.2    Ryan, K.A.3
  • 40
    • 0034974386 scopus 로고    scopus 로고
    • Evaluation of a low dose nonoxynol-9 gel for the prevention of sexually transmitted diseases: A randomized clinical trial
    • Richardson BA, Lavreys L, Martin HL, et al. Evaluation of a low dose nonoxynol-9 gel for the prevention of sexually transmitted diseases: a randomized clinical trial. Sex Transm Dis 2001;28:394-400.
    • (2001) Sex Transm Dis , vol.28 , pp. 394-400
    • Richardson, B.A.1    Lavreys, L.2    Martin, H.L.3
  • 41
    • 33644851726 scopus 로고    scopus 로고
    • Effects of long-term use of nonoxynol-9 on vaginal flora
    • Schreiber CA, Meyn LA, Creinin MD, et al. Effects of long-term use of nonoxynol-9 on vaginal flora. Obstet Gynecol 2006;107:136-43.
    • (2006) Obstet Gynecol , vol.107 , pp. 136-143
    • Schreiber, C.A.1    Meyn, L.A.2    Creinin, M.D.3
  • 42
    • 0033965025 scopus 로고    scopus 로고
    • Safety of multiple daily applications of COL-1492, a nonoxynol-9 vaginal gel, among female sex workers. COL-1492 phase II study group
    • Van Damme L, Chandeying V, Ramjee G, et al. Safety of multiple daily applications of COL-1492, a nonoxynol-9 vaginal gel, among female sex workers. COL-1492 phase II study group. AIDS 2000;14:85-8.
    • (2000) AIDS , vol.14 , pp. 85-88
    • Van Damme, L.1    Chandeying, V.2    Ramjee, G.3
  • 43
    • 0032485243 scopus 로고    scopus 로고
    • Safety evaluation of nonoxynol-9 gel in women at low risk of HIV infection
    • Van Damme L, Niruthisard S, Atisook R. Safety evaluation of nonoxynol-9 gel in women at low risk of HIV infection. AIDS 1998;12:433-7.
    • (1998) AIDS , vol.12 , pp. 433-437
    • Van Damme, L.1    Niruthisard, S.2    Atisook, R.3
  • 45
    • 36348968191 scopus 로고    scopus 로고
    • Nonoxynol-9- a-cyclodextrin inclusion compound and its application for the controlled release of nonoxynol-9 spermicide
    • Whang HS, Hunt MA, Wrench N, et al. Nonoxynol-9- a-cyclodextrin inclusion compound and its application for the controlled release of nonoxynol-9 spermicide. J Appl Polymer Sci 2007;106:4104-9.
    • (2007) J Appl Polymer Sci , vol.106 , pp. 4104-4109
    • Whang, H.S.1    Hunt, M.A.2    Wrench, N.3
  • 46
    • 0031042666 scopus 로고    scopus 로고
    • Measurement and modulation of nonoxynol-9 diffusion and bioactivity against spermatozoa in human cervical mucus
    • Dunmire EN, Katz DF. Measurement and modulation of nonoxynol-9 diffusion and bioactivity against spermatozoa in human cervical mucus. Contraception 1997;55:115- 22.
    • (1997) Contraception , vol.55 , pp. 115-122
    • Dunmire, E.N.1    Katz, D.F.2
  • 47
    • 0030775613 scopus 로고    scopus 로고
    • Quantitation of vaginally administered nonoxynol-9 in premenopausal women
    • Barditch-Crovob P, Witter F, Hamzeh F, et al. Quantitation of vaginally administered nonoxynol-9 in premenopausal women. Contraception 1997;55:261-3.
    • (1997) Contraception , vol.55 , pp. 261-263
    • Barditch-Crovob, P.1    Witter, F.2    Hamzeh, F.3
  • 50
    • 0021832823 scopus 로고
    • Quantitation of vaginal discharge in healthy volunteers
    • Godley MJ. Quantitation of vaginal discharge in healthy volunteers. Br J Obstet Gynaecol 1985;92:739-42.
    • (1985) Br J Obstet Gynaecol , vol.92 , pp. 739-742
    • Godley, M.J.1
  • 51
    • 0019126170 scopus 로고
    • Electrolytes in vaginal fluid during the menstrual cycle of coitally active and inactive women
    • Wagner G, Levin RJ. Electrolytes in vaginal fluid during the menstrual cycle of coitally active and inactive women. J Reprod Fertil 1980;60:17-27.
    • (1980) J Reprod Fertil , vol.60 , pp. 17-27
    • Wagner, G.1    Levin, R.J.2
  • 52
    • 0033025198 scopus 로고    scopus 로고
    • Duration of vaginal retention and potential duration of antiviral activity for five nonoxynol-9 containing intravaginal contraceptives
    • Witter FR, Barditch-Crovob P, Rocco L, Trapnell CB. Duration of vaginal retention and potential duration of antiviral activity for five nonoxynol-9 containing intravaginal contraceptives. Int J Gynecol Obstet 1999; 65:165-70.
    • (1999) Int J Gynecol Obstet , vol.65 , pp. 165-170
    • Witter, F.R.1    Barditch-Crovob, P.2    Rocco, L.3    Trapnell, C.B.4
  • 53
    • 0002970915 scopus 로고
    • Chemical vaginal contraceptives: Preclinical evaluation
    • Mauck CK, Cordero M, Gabelnick HL, et al, eds, New York: Wiley-Liss
    • Doncel GF. Chemical vaginal contraceptives: preclinical evaluation. In Mauck CK, Cordero M, Gabelnick HL, et al., eds. Barrier contraceptives, current status and future prospects. New York: Wiley-Liss 1994:147-62.
    • (1994) Barrier contraceptives, current status and future prospects , pp. 147-162
    • Doncel, G.F.1
  • 54
    • 0030752641 scopus 로고    scopus 로고
    • An evaluation of the amount of N-9 remaining in the vagina up to 4 hrs after insertion of a vaginal contraceptive film [VCF1] containing 70 mg N-9
    • Mauck CK, Allen S, Baker JM, et al. An evaluation of the amount of N-9 remaining in the vagina up to 4 hrs after insertion of a vaginal contraceptive film [VCF1] containing 70 mg N-9. Contraception 1997;56:103-10.
    • (1997) Contraception , vol.56 , pp. 103-110
    • Mauck, C.K.1    Allen, S.2    Baker, J.M.3
  • 55
    • 0015317755 scopus 로고
    • The function of the cervix in fertility
    • Moghissi KS. The function of the cervix in fertility. Fertil Steril 1972;23:295-306.
    • (1972) Fertil Steril , vol.23 , pp. 295-306
    • Moghissi, K.S.1
  • 56
    • 0342913712 scopus 로고
    • Vaginal anatomy and physiology as they relate to sexual intercourse
    • Mauck CK, Cordero M, Gabelnick HL, et al, eds, New York: Wiley-Liss
    • Roy S. Vaginal anatomy and physiology as they relate to sexual intercourse. In Mauck CK, Cordero M, Gabelnick HL, et al., eds. Barrier contraceptives, current status and future prospects. New York: Wiley-Liss 1994:77-89.
    • (1994) Barrier contraceptives, current status and future prospects , pp. 77-89
    • Roy, S.1
  • 57
    • 65249150844 scopus 로고    scopus 로고
    • Posture influences vaginal gel distributions in women: In vivo studies
    • Katz DF, Couchman GM, Driscoll SL, et al. Posture influences vaginal gel distributions in women: In vivo studies. Fertil Steril 2001;76:S18.
    • (2001) Fertil Steril , vol.76
    • Katz, D.F.1    Couchman, G.M.2    Driscoll, S.L.3
  • 58
    • 0034949619 scopus 로고    scopus 로고
    • Distribution of topical medication in the human vagina as imaged by MRI
    • Barnhart K, Pretorius ES, Stolpen A, Malamud D. Distribution of topical medication in the human vagina as imaged by MRI. Fertil Steril 2001;76:189-95.
    • (2001) Fertil Steril , vol.76 , pp. 189-195
    • Barnhart, K.1    Pretorius, E.S.2    Stolpen, A.3    Malamud, D.4
  • 59
    • 0034974658 scopus 로고    scopus 로고
    • Distribution of spermicide containing nonoxynol-9 in the vaginal canal and the upper female reproductive tract
    • Barnhart KT, Pretorius ES, Stolpen A, Malamud D. Distribution of spermicide containing nonoxynol-9 in the vaginal canal and the upper female reproductive tract. Hum Reprod 2001;16:1151-4.
    • (2001) Hum Reprod , vol.16 , pp. 1151-1154
    • Barnhart, K.T.1    Pretorius, E.S.2    Stolpen, A.3    Malamud, D.4
  • 60
    • 39149145460 scopus 로고    scopus 로고
    • Vaginal distribution of Replens1 and K-Y1 jelly using three imaging techniques
    • Mauck CK, Katz D, Sandefer EP, et al. Vaginal distribution of Replens1 and K-Y1 jelly using three imaging techniques. Contraception 2008;77:195-204.
    • (2008) Contraception , vol.77 , pp. 195-204
    • Mauck, C.K.1    Katz, D.2    Sandefer, E.P.3
  • 61
    • 0023412736 scopus 로고
    • Contraceptive failure in the United States: A critical review of the literature
    • Trussell J, Kost K. Contraceptive failure in the United States: a critical review of the literature. Stud Fam Plann 1987;18:237-83.
    • (1987) Stud Fam Plann , vol.18 , pp. 237-283
    • Trussell, J.1    Kost, K.2
  • 62
    • 0022644502 scopus 로고
    • Comparison of the action of nonoxynol-9 and chlorhexidine on sperm
    • Sharman D, Chantler E, Elstein M, et al. Comparison of the action of nonoxynol-9 and chlorhexidine on sperm. Fertil Steril 1986;45:259-65.
    • (1986) Fertil Steril , vol.45 , pp. 259-265
    • Sharman, D.1    Chantler, E.2    Elstein, M.3
  • 63
    • 0026604867 scopus 로고
    • The effect of cocaine on sperm motility characteristics and bovine cervical mucus penetration
    • Hurd WW, Kelly MS, Ohl DA, et al. The effect of cocaine on sperm motility characteristics and bovine cervical mucus penetration. Fertil Steril 1992;57: 178-82.
    • (1992) Fertil Steril , vol.57 , pp. 178-182
    • Hurd, W.W.1    Kelly, M.S.2    Ohl, D.A.3
  • 64
    • 0019400922 scopus 로고
    • Evaluation of male infertility with an in vitro cervical mucus penetration test
    • Alexander NJ. Evaluation of male infertility with an in vitro cervical mucus penetration test. Fertil Steril 1981;36:201-8.
    • (1981) Fertil Steril , vol.36 , pp. 201-208
    • Alexander, N.J.1
  • 65
    • 0342597355 scopus 로고
    • Zatuchni GI, Sobrero AJ, Speide JJ, Sciarra JJ, eds, Hagerstown, MD: Harper and Row
    • Zatuchni GI, Sobrero AJ, Speide JJ, Sciarra JJ, eds. Vaginal contraceptives: New developments. Hagerstown, MD: Harper and Row, 1979.
    • (1979) Vaginal contraceptives: New developments
  • 66
    • 0030801222 scopus 로고    scopus 로고
    • Alteration of human sperm kinematics in cervical mucus due to nonoxynol-9
    • Dunmire EN, Katz F. Alteration of human sperm kinematics in cervical mucus due to nonoxynol-9. Contraception 1997;55:209-17.
    • (1997) Contraception , vol.55 , pp. 209-217
    • Dunmire, E.N.1    Katz, F.2
  • 67
    • 0026576170 scopus 로고
    • The relation of computer-based measures of sperm morphology and motility to male infertility
    • Boyle CA, Khoury MJ, Katz DF, et al. The relation of computer-based measures of sperm morphology and motility to male infertility. Epidemiology 1992;3:239-46.
    • (1992) Epidemiology , vol.3 , pp. 239-246
    • Boyle, C.A.1    Khoury, M.J.2    Katz, D.F.3
  • 68
    • 0026674535 scopus 로고
    • Effects of the aggregation state of amphotericin B on its toxicity to mice
    • Barwicz J, Christian S, Gruda I. Effects of the aggregation state of amphotericin B on its toxicity to mice. Antimicrob Agents Chemother 1992;36:2310-5.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 2310-2315
    • Barwicz, J.1    Christian, S.2    Gruda, I.3
  • 69
    • 0029005047 scopus 로고
    • Micelle/ monomer control over the membrane-disrupting properties of an amphiphilic antibiotic
    • Yamashita K, Janout V, Bernard EM, et al. Micelle/ monomer control over the membrane-disrupting properties of an amphiphilic antibiotic. J Am Chem Soc 1995;117:249-53.
    • (1995) J Am Chem Soc , vol.117 , pp. 249-253
    • Yamashita, K.1    Janout, V.2    Bernard, E.M.3
  • 70
    • 0026889502 scopus 로고
    • Correlation between hydrophobicity and resistance to nonoxynol-9 and vancomycin for urogenital isolates of lactobacilli
    • Tomecjek L, Reid G, Cuprerus PL, et al. Correlation between hydrophobicity and resistance to nonoxynol-9 and vancomycin for urogenital isolates of lactobacilli. FEMS Microbiol Lett 1992;73:101-4.
    • (1992) FEMS Microbiol Lett , vol.73 , pp. 101-104
    • Tomecjek, L.1    Reid, G.2    Cuprerus, P.L.3
  • 71
    • 0031891991 scopus 로고    scopus 로고
    • Safety study of nonoxynol-9 as a vaginal microbicide: Evidence of adverse effects
    • Stafford M, Ward H, Flanagan A, et al. Safety study of nonoxynol-9 as a vaginal microbicide: evidence of adverse effects. J Acquir Immune Defic Syndr Hum Retrovirol 1998;17:327-31.
    • (1998) J Acquir Immune Defic Syndr Hum Retrovirol , vol.17 , pp. 327-331
    • Stafford, M.1    Ward, H.2    Flanagan, A.3
  • 72
    • 0033636302 scopus 로고    scopus 로고
    • Nonoxynol-9 causes rapid exfoliation of sheets of rectal epithelium
    • Phillips D, Taylor C, Zacharopoulos V, Maguire R. Nonoxynol-9 causes rapid exfoliation of sheets of rectal epithelium. Contraception 2000;62:149-54.
    • (2000) Contraception , vol.62 , pp. 149-154
    • Phillips, D.1    Taylor, C.2    Zacharopoulos, V.3    Maguire, R.4
  • 74
    • 0032996769 scopus 로고    scopus 로고
    • Protective effect of a thermoreversible gel against the toxicity of nonoxynol- 9
    • Gagne N, Cormier H, Omar R, et al. Protective effect of a thermoreversible gel against the toxicity of nonoxynol- 9. Sex Transm Dis 1999;26:177-83.
    • (1999) Sex Transm Dis , vol.26 , pp. 177-183
    • Gagne, N.1    Cormier, H.2    Omar, R.3
  • 75
    • 0013537560 scopus 로고
    • Studies on the association of 14C-povidone-131I-iodine complex with red blood cells and bacterial membranes
    • Digenis GA and Ansell J, eds, Lexington: University of Kentucky
    • Digenis GA, Rokem SS, Eckert D, Blecher L. Studies on the association of 14C-povidone-131I-iodine complex with red blood cells and bacterial membranes. In Digenis GA and Ansell J, eds. Proceedings of the International Symposium on Povidone. Lexington: University of Kentucky 1983:302-11.
    • (1983) Proceedings of the International Symposium on Povidone , pp. 302-311
    • Digenis, G.A.1    Rokem, S.S.2    Eckert, D.3    Blecher, L.4
  • 76
    • 0015359847 scopus 로고
    • The protective effect of polyvinylpyrrolidone and hydroxyethyl starch on noncryogenic injury to red blood cells
    • Ben-David A, Gavendo S. The protective effect of polyvinylpyrrolidone and hydroxyethyl starch on noncryogenic injury to red blood cells. Cryobiology 1972;9:192-7.
    • (1972) Cryobiology , vol.9 , pp. 192-197
    • Ben-David, A.1    Gavendo, S.2
  • 77
    • 23144464358 scopus 로고    scopus 로고
    • Coprecipitation of nonoxynol-9 with polyvinylpyrrolidone to decrease vaginal irritation potential while spermicidal potency
    • Fowler PT, Doncel GF, Bummer PM, Digenis GA. Coprecipitation of nonoxynol-9 with polyvinylpyrrolidone to decrease vaginal irritation potential while spermicidal potency. AAPS Pharm Sci Tech 2003;4:1-8.
    • (2003) AAPS Pharm Sci Tech , vol.4 , pp. 1-8
    • Fowler, P.T.1    Doncel, G.F.2    Bummer, P.M.3    Digenis, G.A.4
  • 78
    • 0031970353 scopus 로고    scopus 로고
    • Assessment of a tablet drug delivery system incorporating nonoxynol-9 coprecipitated with polyvinylpyrrolidone in preventing the onset of pregnancy in rabbits
    • Zavos PM, Correa JR, Zarmakoupis-Zavos PN. Assessment of a tablet drug delivery system incorporating nonoxynol-9 coprecipitated with polyvinylpyrrolidone in preventing the onset of pregnancy in rabbits. Fertil Steril 1998;69:768-73.
    • (1998) Fertil Steril , vol.69 , pp. 768-773
    • Zavos, P.M.1    Correa, J.R.2    Zarmakoupis-Zavos, P.N.3
  • 79
    • 0030200311 scopus 로고    scopus 로고
    • Comparative spermicidal performance of iodinated and non-iodinated contraceptive formulations of nonoxynol-9 co-precipitated with polyvinylpyrrolidone
    • Zavos PM, Correa JR, Nasek D, et al. Comparative spermicidal performance of iodinated and non-iodinated contraceptive formulations of nonoxynol-9 co-precipitated with polyvinylpyrrolidone. Contraception 1996;54: 39-41.
    • (1996) Contraception , vol.54 , pp. 39-41
    • Zavos, P.M.1    Correa, J.R.2    Nasek, D.3
  • 80
    • 0030030609 scopus 로고    scopus 로고
    • Comparative in vitro spermicidal activity of chelating agents and synergistic effect with nonoxynol-9 on human sperm functionality
    • Lee CH, Bagdon R, Chien YW. Comparative in vitro spermicidal activity of chelating agents and synergistic effect with nonoxynol-9 on human sperm functionality. J Pharm Sci 1996;85:91-5.
    • (1996) J Pharm Sci , vol.85 , pp. 91-95
    • Lee, C.H.1    Bagdon, R.2    Chien, Y.W.3
  • 81
    • 0028839359 scopus 로고
    • Complementary effects of propranolol and nonoxynol- 9 upon human sperm motility
    • White DR, Clarkson JS, Ratnasooriya WD, Aitken RJ. Complementary effects of propranolol and nonoxynol- 9 upon human sperm motility. Contraception 1995;52: 241-7.
    • (1995) Contraception , vol.52 , pp. 241-247
    • White, D.R.1    Clarkson, J.S.2    Ratnasooriya, W.D.3    Aitken, R.J.4
  • 82
    • 34249705209 scopus 로고    scopus 로고
    • Apotential antiimplantation and spermicidal strategy: Putative derivatives of nonoxynol-9 and anti-inflammatory agents and their spermicidal activity
    • Ingram MJ, Zeller E, Moss GP, Hall CE.Apotential antiimplantation and spermicidal strategy: Putative derivatives of nonoxynol-9 and anti-inflammatory agents and their spermicidal activity. Eur J Contracept Reprod Health Care 2006;11:258-61.
    • (2006) Eur J Contracept Reprod Health Care , vol.11 , pp. 258-261
    • Ingram, M.J.1    Zeller, E.2    Moss, G.P.3    Hall, C.E.4


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