메뉴 건너뛰기




Volumn 121, Issue 3, 2014, Pages 510-527

Sevoflurane induces tau phosphorylation and glycogen synthase kinase 3β activation in young mice

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 6; LITHIUM; POSTSYNAPTIC DENSITY PROTEIN 95; SEVOFLURANE; TAU PROTEIN; ETHER DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INHALATION ANESTHETIC AGENT;

EID: 84921691623     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000278     Document Type: Article
Times cited : (128)

References (75)
  • 3
    • 79952199825 scopus 로고    scopus 로고
    • Early childhood general anaesthesia exposure and neurocognitive development
    • Sun L: Early childhood general anaesthesia exposure and neurocognitive development. Br J Anaesth 2010; 105(suppl 1):i61-8.
    • (2010) Br J Anaesth , vol.105 , pp. i61-i68
    • Sun, L.1
  • 5
    • 62349116245 scopus 로고    scopus 로고
    • Neonatal exposure to sevoflurane induces abnormal social behaviors and deficits in fear conditioning in mice
    • Satomoto M, Satoh Y, Terui K, Miyao H, Takishima K, Ito M, Imaki J: Neonatal exposure to sevoflurane induces abnormal social behaviors and deficits in fear conditioning in mice. Anesthesiology 2009; 110:628-37.
    • (2009) Anesthesiology , vol.110 , pp. 628-637
    • Satomoto, M.1    Satoh, Y.2    Terui, K.3    Miyao, H.4    Takishima, K.5    Ito, M.6    Imaki, J.7
  • 12
    • 0028305902 scopus 로고
    • Paired helical filament tau in Alzheimer's disease. The kinase connection
    • Trojanowski JQ, Lee VM: Paired helical filament tau in Alzheimer's disease. The kinase connection. Am J Pathol 1994; 144:449-53.
    • (1994) Am J Pathol , vol.144 , pp. 449-453
    • Trojanowski, J.Q.1    Lee, V.M.2
  • 14
    • 56349119351 scopus 로고    scopus 로고
    • Linking Abeta and tau in late-onset Alzheimer's disease: A dual pathway hypothesis
    • Small SA, Duff K: Linking Abeta and tau in late-onset Alzheimer's disease: A dual pathway hypothesis. Neuron 2008; 60:534-42.
    • (2008) Neuron , vol.60 , pp. 534-542
    • Small, S.A.1    Duff, K.2
  • 16
    • 84863337843 scopus 로고    scopus 로고
    • Alzheimer mechanisms and therapeutic strategies
    • Huang Y, Mucke L: Alzheimer mechanisms and therapeutic strategies. Cell 2012; 148:1204-22.
    • (2012) Cell , vol.148 , pp. 1204-1222
    • Huang, Y.1    Mucke, L.2
  • 20
    • 77956861933 scopus 로고    scopus 로고
    • Tau hyperphosphorylation is associated with memory impairment after exposure to 1.5% isoflurane without temperature maintenance in rats
    • Tan W, Cao X, Wang J, Lv H, Wu B, Ma H: Tau hyperphosphorylation is associated with memory impairment after exposure to 1.5% isoflurane without temperature maintenance in rats. Eur J Anaesthesiol 2010; 27:835-41.
    • (2010) Eur J Anaesthesiol , vol.27 , pp. 835-841
    • Tan, W.1    Cao, X.2    Wang, J.3    Lv, H.4    Wu, B.5    Ma, H.6
  • 21
    • 79952629918 scopus 로고    scopus 로고
    • Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission
    • Van der Jeugd A, Ahmed T, Burnouf S, Belarbi K, Hamdame M, Grosjean ME, Humez S, Balschun D, Blum D, Buée L, D'Hooge R: Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission. Neurobiol Learn Mem 2011; 95:296-304.
    • (2011) Neurobiol Learn Mem , vol.95 , pp. 296-304
    • Van Der Jeugd, A.1    Ahmed, T.2    Burnouf, S.3    Belarbi, K.4    Hamdame, M.5    Grosjean, M.E.6    Humez, S.7    Balschun, D.8    Blum, D.9    Buée, L.10    D'Hooge, R.11
  • 22
    • 69449093036 scopus 로고    scopus 로고
    • Agedependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology
    • Polydoro M, Acker CM, Duff K, Castillo PE, Davies P: Agedependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology. J Neurosci 2009; 29:10741-9.
    • (2009) J Neurosci , vol.29 , pp. 10741-10749
    • Polydoro, M.1    Acker, C.M.2    Duff, K.3    Castillo, P.E.4    Davies, P.5
  • 24
    • 0032566623 scopus 로고    scopus 로고
    • Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase
    • Wang JZ, Wu Q, Smith A, Grundke-Iqbal I, Iqbal K: Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase. FEBS Lett 1998; 436:28-34.
    • (1998) FEBS Lett , vol.436 , pp. 28-34
    • Wang, J.Z.1    Wu, Q.2    Smith, A.3    Grundke-Iqbal, I.4    Iqbal, K.5
  • 25
    • 0037163879 scopus 로고    scopus 로고
    • Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3
    • Liu F, Iqbal K, Grundke-Iqbal I, Gong CX: Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3β. FEBS Lett 2002; 530:209-14.
    • (2002) FEBS Lett , vol.530 , pp. 209-214
    • Liu, F.1    Iqbal, K.2    Grundke-Iqbal, I.3    Gong, C.X.4
  • 26
    • 0033302735 scopus 로고    scopus 로고
    • Tau protein in normal and Alzheimer's disease brain: An update
    • Johnson GV, Hartigan JA: Tau protein in normal and Alzheimer's disease brain: An update. J Alzheimers Dis 1999; 1:329-51.
    • (1999) J Alzheimers Dis , vol.1 , pp. 329-351
    • Johnson, G.V.1    Hartigan, J.A.2
  • 27
    • 0032987650 scopus 로고    scopus 로고
    • Phosphorylation of tau protein by recombinant GSK-3β: Pronounced phosphorylation at select ser/thr-pro motifs but no phosphorylation at ser262 in the repeat domain
    • Godemann R, Biernat J, Mandelkow E, Mandelkow EM: Phosphorylation of tau protein by recombinant GSK-3β: Pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain. FEBS Lett 1999; 454:157-64.
    • (1999) FEBS Lett , vol.454 , pp. 157-164
    • Godemann, R.1    Biernat, J.2    Mandelkow, E.3    Mandelkow, E.M.4
  • 28
    • 0032578024 scopus 로고    scopus 로고
    • Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of alzheimer's disease neurofibrillary degeneration
    • Pei JJ, Grundke-Iqbal I, Iqbal K, Bogdanovic N, Winblad B, Cowburn RF: Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration. Brain Res 1998; 797:267-77.
    • (1998) Brain Res , vol.797 , pp. 267-277
    • Pei, J.J.1    Grundke-Iqbal, I.2    Iqbal, K.3    Bogdanovic, N.4    Winblad, B.5    Cowburn, R.F.6
  • 29
    • 0035087703 scopus 로고    scopus 로고
    • Localization of active forms of C-jun kinase ( JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration
    • Pei JJ, Braak E, Braak H, Grundke-Iqbal I, Iqbal K, Winblad B, Cowburn RF: Localization of active forms of C-jun kinase ( JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration. J Alzheimers Dis 2001; 3:41-8.
    • (2001) J Alzheimers Dis , vol.3 , pp. 41-48
    • Pei, J.J.1    Braak, E.2    Braak, H.3    Grundke-Iqbal, I.4    Iqbal, K.5    Winblad, B.6    Cowburn, R.F.7
  • 30
    • 3142712947 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase ( JNK)
    • Yoshida H, Hastie CJ, McLauchlan H, Cohen P, Goedert M: Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase ( JNK). J Neurochem 2004; 90:352-8.
    • (2004) J Neurochem , vol.90 , pp. 352-358
    • Yoshida, H.1    Hastie, C.J.2    Mclauchlan, H.3    Cohen, P.4    Goedert, M.5
  • 31
    • 43249124363 scopus 로고    scopus 로고
    • Microtubule-associated protein tau in development, degeneration and protection of neurons
    • Wang JZ, Liu F: Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol 2008; 85:148-75.
    • (2008) Prog Neurobiol , vol.85 , pp. 148-175
    • Wang, J.Z.1    Liu, F.2
  • 32
    • 84872551783 scopus 로고    scopus 로고
    • Abnormal hyperphosphorylation of tau: Sites, regulation, and molecular mechanism of neurofibrillary degeneration
    • Wang JZ, Xia YY, Grundke-Iqbal I, Iqbal K: Abnormal hyperphosphorylation of tau: Sites, regulation, and molecular mechanism of neurofibrillary degeneration. J Alzheimers Dis 2013; 33(suppl 1):S123-39.
    • (2013) J Alzheimers Dis , vol.33 , pp. S123-S139
    • Wang, J.Z.1    Xia, Y.Y.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 34
    • 0033965591 scopus 로고    scopus 로고
    • Distribution of tau protein kinase I/glycogen synthase kinase-3β, phosphatases 2A and 2B, and phosphorylated tau in the developing rat brain
    • Takahashi M, Tomizawa K, Ishiguro K: Distribution of tau protein kinase I/glycogen synthase kinase-3β, phosphatases 2A and 2B, and phosphorylated tau in the developing rat brain. Brain Res 2000; 857:193-206.
    • (2000) Brain Res , vol.857 , pp. 193-206
    • Takahashi, M.1    Tomizawa, K.2    Ishiguro, K.3
  • 35
    • 0026784416 scopus 로고
    • P42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]
    • Goedert M, Cohen ES, Jakes R, Cohen P: p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]. FEBS Lett 1992; 312:95-9.
    • (1992) FEBS Lett , vol.312 , pp. 95-99
    • Goedert, M.1    Cohen, E.S.2    Jakes, R.3    Cohen, P.4
  • 36
    • 0029995590 scopus 로고    scopus 로고
    • Restoration of biological activity of alzheimer abnormally phosphorylated tau by dephosphorylation with protein phosphatase-2A, -2B and -1
    • Wang JZ, Grundke-Iqbal I, Iqbal K: Restoration of biological activity of Alzheimer abnormally phosphorylated tau by dephosphorylation with protein phosphatase-2A, -2B and -1. Brain Res Mol Brain Res 1996; 38:200-8.
    • (1996) Brain Res Mol Brain Res , vol.38 , pp. 200-208
    • Wang, J.Z.1    Grundke-Iqbal, I.2    Iqbal, K.3
  • 37
    • 0030602070 scopus 로고    scopus 로고
    • Inhibition of protein phosphatase-2B (calcineurin) activity towards Alzheimer abnormally phosphorylated tau by neuroleptics
    • Gong CX, Shaikh S, Grundke-Iqbal I, Iqbal K: Inhibition of protein phosphatase-2B (calcineurin) activity towards Alzheimer abnormally phosphorylated tau by neuroleptics. Brain Res 1996; 741:95-102.
    • (1996) Brain Res , vol.741 , pp. 95-102
    • Gong, C.X.1    Shaikh, S.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 38
    • 0029113874 scopus 로고
    • Phosphatase activity toward abnormally phosphorylated tau: Decrease in Alzheimer disease brain
    • Gong CX, Shaikh S, Wang JZ, Zaidi T, Grundke-Iqbal I, Iqbal K: Phosphatase activity toward abnormally phosphorylated tau: Decrease in Alzheimer disease brain. J Neurochem 1995; 65:732-8.
    • (1995) J Neurochem , vol.65 , pp. 732-738
    • Gong, C.X.1    Shaikh, S.2    Wang, J.Z.3    Zaidi, T.4    Grundke-Iqbal, I.5    Iqbal, K.6
  • 39
    • 0028172239 scopus 로고
    • The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases
    • Mawal-Dewan M, Henley J, Van de Voorde A, Trojanowski JQ, Lee VM: The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases. J Biol Chem 1994; 269:30981-7.
    • (1994) J Biol Chem , vol.269 , pp. 30981-30987
    • Mawal-Dewan, M.1    Henley, J.2    Van De Voorde, A.3    Trojanowski, J.Q.4    Lee, V.M.5
  • 44
    • 84862662873 scopus 로고    scopus 로고
    • Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and aβ generation
    • Dong Y, Wu X, Xu Z, Zhang Y, Xie Z: Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Aβ generation. PLoS One 2012; 7:e39386.
    • (2012) PLoS One , vol.7 , pp. e39386
    • Dong, Y.1    Wu, X.2    Xu, Z.3    Zhang, Y.4    Xie, Z.5
  • 47
    • 0030957966 scopus 로고    scopus 로고
    • SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density
    • Takeuchi M, Hata Y, Hirao K, Toyoda A, Irie M, Takai Y: SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. J Biol Chem 1997; 272:11943-51.
    • (1997) J Biol Chem , vol.272 , pp. 11943-11951
    • Takeuchi, M.1    Hata, Y.2    Hirao, K.3    Toyoda, A.4    Irie, M.5    Takai, Y.6
  • 48
    • 78650347671 scopus 로고    scopus 로고
    • Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration
    • Liu Q, Trotter J, Zhang J, Peters MM, Cheng H, Bao J, Han X, Weeber EJ, Bu G: Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. J Neurosci 2010; 30:17068-78.
    • (2010) J Neurosci , vol.30 , pp. 17068-17078
    • Liu, Q.1    Trotter, J.2    Zhang, J.3    Peters, M.M.4    Cheng, H.5    Bao, J.6    Han, X.7    Weeber, E.J.8    Bu, G.9
  • 49
    • 0030868557 scopus 로고    scopus 로고
    • Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3
    • Hong M, Chen DC, Klein PS, Lee VM: Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3. J Biol Chem 1997; 272:25326-32.
    • (1997) J Biol Chem , vol.272 , pp. 25326-25332
    • Hong, M.1    Chen, D.C.2    Klein, P.S.3    Lee, V.M.4
  • 50
    • 77953027616 scopus 로고    scopus 로고
    • Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and alzheimer disease transgenic mice
    • Lu Y, Wu X, Dong Y, Xu Z, Zhang Y, Xie Z: Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice. Anesthesiology 2010; 112:1404-16.
    • (2010) Anesthesiology , vol.112 , pp. 1404-1416
    • Lu, Y.1    Wu, X.2    Dong, Y.3    Xu, Z.4    Zhang, Y.5    Xie, Z.6
  • 53
    • 58149269462 scopus 로고    scopus 로고
    • The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid β-protein level in vivo
    • Xie Z, Culley DJ, Dong Y, Zhang G, Zhang B, Moir RD, Frosch MP, Crosby G, Tanzi RE: The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid β-protein level in vivo. Ann Neurol 2008; 64:618-27.
    • (2008) Ann Neurol , vol.64 , pp. 618-627
    • Xie, Z.1    Culley, D.J.2    Dong, Y.3    Zhang, G.4    Zhang, B.5    Moir, R.D.6    Frosch, M.P.7    Crosby, G.8    Tanzi, R.E.9
  • 54
    • 0027978816 scopus 로고
    • The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line l6 is blocked by wortmannin, but not by rapamycin: Evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in l6 cells between ras and raf
    • Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P: The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: Evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf. Biochem J 1994; 303(Pt 1): 21-6.
    • (1994) Biochem J , vol.303 , pp. 21-26
    • Cross, D.A.1    Alessi, D.R.2    Vandenheede, J.R.3    Mcdowell, H.E.4    Hundal, H.S.5    Cohen, P.6
  • 55
    • 0027515127 scopus 로고
    • Inactivation of glycogen synthase kinase-3β by phosphorylation: New kinase connections in insulin and growth-factor signalling
    • Sutherland C, Leighton IA, Cohen P: Inactivation of glycogen synthase kinase-3β by phosphorylation: New kinase connections in insulin and growth-factor signalling. Biochem J 1993; 296(Pt 1):15-9.
    • (1993) Biochem J , vol.296 , pp. 15-19
    • Sutherland, C.1    Leighton, I.A.2    Cohen, P.3
  • 56
    • 0027960448 scopus 로고
    • Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation
    • Stambolic V, Woodgett JR: Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation. Biochem J 1994; 303(Pt 3):701-4.
    • (1994) Biochem J , vol.303 , pp. 701-704
    • Stambolic, V.1    Woodgett, J.R.2
  • 57
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA: Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378:785-9.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 58
    • 0442276554 scopus 로고    scopus 로고
    • The glamour and gloom of glycogen synthase kinase-3
    • Jope RS, Johnson GV: The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci 2004; 29:95-102.
    • (2004) Trends Biochem Sci , vol.29 , pp. 95-102
    • Jope, R.S.1    Johnson, G.V.2
  • 59
    • 33646795341 scopus 로고    scopus 로고
    • Targeting GS K-3: A promising approach for cancer therapy?
    • Ougolkov AV, Billadeau DD: Targeting GS K-3: A promising approach for cancer therapy? Future Oncol 2006; 2:91-100.
    • (2006) Future Oncol , vol.2 , pp. 91-100
    • Ougolkov, A.V.1    Billadeau, D.D.2
  • 62
    • 78649517775 scopus 로고    scopus 로고
    • Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats
    • Cao XZ, Ma H, Wang JK, Liu F, Wu BY, Tian AY, Wang LL, Tan WF: Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats. Prog Neuropsychopharmacol Biol Psychiatry 2010; 34:1426-32.
    • (2010) Prog Neuropsychopharmacol Biol Psychiatry , vol.34 , pp. 1426-1432
    • Cao, X.Z.1    Ma, H.2    Wang, J.K.3    Liu, F.4    Wu, B.Y.5    Tian, A.Y.6    Wang, L.L.7    Tan, W.F.8
  • 63
    • 51449117700 scopus 로고    scopus 로고
    • Exaggerated sickness behavior and brain pro inflammatory cytokine expression in aged mice in response to intra cerebroventricular lipopolysaccharide
    • Huang Y, Henry CJ, Dantzer R, Johnson RW, Godbout JP: Exaggerated sickness behavior and brain pro inflammatory cytokine expression in aged mice in response to intra cerebroventricular lipopolysaccharide. Neurobiol Aging 2008; 29:1744-53.
    • (2008) Neurobiol Aging , vol.29 , pp. 1744-1753
    • Huang, Y.1    Henry, C.J.2    Dantzer, R.3    Johnson, R.W.4    Godbout, J.P.5
  • 64
    • 77950128963 scopus 로고    scopus 로고
    • Correlations between peripheral blood mononuclear cell production of BDNF, TNF-α, IL -6, IL -10 and cognitive performances in multiple sclerosis patients
    • Patanella AK, Zinno M, Quaranta D, Nociti V, Frisullo G, Gainotti G, Tonali PA, Batocchi AP, Marra C: Correlations between peripheral blood mononuclear cell production of BDNF, TNF-α, IL -6, IL -10 and cognitive performances in multiple sclerosis patients. J Neurosci Res 2010; 88:1106-12.
    • (2010) J Neurosci Res , vol.88 , pp. 1106-1112
    • Patanella, A.K.1    Zinno, M.2    Quaranta, D.3    Nociti, V.4    Frisullo, G.5    Gainotti, G.6    Tonali, P.A.7    Batocchi, A.P.8    Marra, C.9
  • 65
    • 79952245068 scopus 로고    scopus 로고
    • Elevated postoperative inflammatory biomarkers are associated with short- And medium-term cognitive dysfunction after coronary artery surgery
    • Hudetz JA, Gandhi SD, Iqbal Z, Patterson KM, Pagel PS: Elevated postoperative inflammatory biomarkers are associated with short- And medium-term cognitive dysfunction after coronary artery surgery. J Anesth 2011; 25:1-9.
    • (2011) J Anesth , vol.25 , pp. 1-9
    • Hudetz, J.A.1    Gandhi, S.D.2    Iqbal, Z.3    Patterson, K.M.4    Pagel, P.S.5
  • 67
    • 84885450496 scopus 로고    scopus 로고
    • An updated review of the optimal lithium dosage regimen for renal protection
    • Carter L, Zolezzi M, Lewczyk A: An updated review of the optimal lithium dosage regimen for renal protection. Can J Psychiatry 2013; 58:595-600.
    • (2013) Can J Psychiatry , vol.58 , pp. 595-600
    • Carter, L.1    Zolezzi, M.2    Lewczyk, A.3
  • 68
    • 84894189382 scopus 로고    scopus 로고
    • Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing p301l tau mutant and tau-tubulin kinase 1
    • Asai H, Ikezu S, Woodbury ME, Yonemoto GM, Cui L, Ikezu T: Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1. Am J Pathol 2014; 184:808-18.
    • (2014) Am J Pathol , vol.184 , pp. 808-818
    • Asai, H.1    Ikezu, S.2    Woodbury, M.E.3    Yonemoto, G.M.4    Cui, L.5    Ikezu, T.6
  • 69
    • 7244242262 scopus 로고    scopus 로고
    • Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human p301s tau protein
    • Bellucci A, Westwood AJ, Ingram E, Casamenti F, Goedert M, Spillantini MG: Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein. Am J Pathol 2004; 165:1643-52.
    • (2004) Am J Pathol , vol.165 , pp. 1643-1652
    • Bellucci, A.1    Westwood, A.J.2    Ingram, E.3    Casamenti, F.4    Goedert, M.5    Spillantini, M.G.6
  • 71
    • 25644456097 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
    • Kitazawa M, Oddo S, Yamasaki TR, Green KN, LaFerla FM: Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci 2005; 25:8843-53.
    • (2005) J Neurosci , vol.25 , pp. 8843-8853
    • Kitazawa, M.1    Oddo, S.2    Yamasaki, T.R.3    Green, K.N.4    LaFerla, F.M.5
  • 74
    • 84887915500 scopus 로고    scopus 로고
    • Sevoflurane inhibits neurogenesis and the wnt-catenin signaling pathway in mouse neural progenitor cells
    • Zhang Y, Dong Y, Zheng H, Shie V, Wang H, Busscher JJ, Yue Y, Xu Z, Xie Z: Sevoflurane inhibits neurogenesis and the Wnt-catenin signaling pathway in mouse neural progenitor cells. Curr Mol Med 2013; 13:1446-54.
    • (2013) Curr Mol Med , vol.13 , pp. 1446-1454
    • Zhang, Y.1    Dong, Y.2    Zheng, H.3    Shie, V.4    Wang, H.5    Busscher, J.J.6    Yue, Y.7    Xu, Z.8    Xie, Z.9
  • 75


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.