메뉴 건너뛰기




Volumn 393, Issue 2, 2014, Pages 195-208

The role of homeobox genes in retinal development and disease

Author keywords

Anophthalmia; Coloboma; Homeobox; Retina; Transcription factor; Vertebrate

Indexed keywords

FIBROBLAST GROWTH FACTOR; HOMEODOMAIN PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR;

EID: 84921651086     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2014.07.004     Document Type: Review
Times cited : (42)

References (188)
  • 3
    • 0029906061 scopus 로고    scopus 로고
    • Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins
    • Agulnick A.D., Taira M., Breen J.J., Tanaka T., Dawid I.B., Westphal H. Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins. Nature 1996, 384:270-272.
    • (1996) Nature , vol.384 , pp. 270-272
    • Agulnick, A.D.1    Taira, M.2    Breen, J.J.3    Tanaka, T.4    Dawid, I.B.5    Westphal, H.6
  • 4
    • 0034312313 scopus 로고    scopus 로고
    • Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye
    • Ashery-Padan R., Marquardt T., Zhou X., Gruss P. Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev. 2000, 14:2701-2711.
    • (2000) Genes Dev. , vol.14 , pp. 2701-2711
    • Ashery-Padan, R.1    Marquardt, T.2    Zhou, X.3    Gruss, P.4
  • 7
    • 62549095466 scopus 로고    scopus 로고
    • Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells
    • Badea T.C., Cahill H., Ecker J., Hattar S., Nathans J. Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells. Neuron 2009, 61:852-864.
    • (2009) Neuron , vol.61 , pp. 852-864
    • Badea, T.C.1    Cahill, H.2    Ecker, J.3    Hattar, S.4    Nathans, J.5
  • 10
    • 80051797691 scopus 로고    scopus 로고
    • The genetics of anophthalmia and microphthalmia
    • Bardakjian T.M., Schneider A. The genetics of anophthalmia and microphthalmia. Curr. Opin. Ophthalmol. 2011, 22:309-313.
    • (2011) Curr. Opin. Ophthalmol. , vol.22 , pp. 309-313
    • Bardakjian, T.M.1    Schneider, A.2
  • 11
    • 84876328551 scopus 로고    scopus 로고
    • The homeobox gene Otx2 in development and disease
    • Beby F., Lamonerie T. The homeobox gene Otx2 in development and disease. Exp. Eye Res. 2013, 111:9-16.
    • (2013) Exp. Eye Res. , vol.111 , pp. 9-16
    • Beby, F.1    Lamonerie, T.2
  • 12
    • 0033386714 scopus 로고    scopus 로고
    • The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain
    • Bertuzzi S., Hindges R., Mui S.H., O'Leary D.D., Lemke G. The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Genes Dev. 1999, 13:3092-3105.
    • (1999) Genes Dev. , vol.13 , pp. 3092-3105
    • Bertuzzi, S.1    Hindges, R.2    Mui, S.H.3    O'Leary, D.D.4    Lemke, G.5
  • 13
    • 0037106121 scopus 로고    scopus 로고
    • Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt
    • Bessa J., Gebelein B., Pichaud F., Casares F., Mann R.S. Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt. Genes Dev. 2002, 16:2415-2427.
    • (2002) Genes Dev. , vol.16 , pp. 2415-2427
    • Bessa, J.1    Gebelein, B.2    Pichaud, F.3    Casares, F.4    Mann, R.S.5
  • 14
    • 42149167968 scopus 로고    scopus 로고
    • Meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye
    • Bessa J., Tavares M.J., Santos J., Kikuta H., Laplante M., Becker T.S., Gomez-Skarmeta J.L., Casares F. meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye. Development 2008, 135:799-803.
    • (2008) Development , vol.135 , pp. 799-803
    • Bessa, J.1    Tavares, M.J.2    Santos, J.3    Kikuta, H.4    Laplante, M.5    Becker, T.S.6    Gomez-Skarmeta, J.L.7    Casares, F.8
  • 15
    • 0035977135 scopus 로고    scopus 로고
    • Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes
    • Blackshaw S., Fraioli R.E., Furukawa T., Cepko C.L. Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes. Cell 2001, 107:579-589.
    • (2001) Cell , vol.107 , pp. 579-589
    • Blackshaw, S.1    Fraioli, R.E.2    Furukawa, T.3    Cepko, C.L.4
  • 16
    • 13444249487 scopus 로고    scopus 로고
    • Genomic amplification of orthodenticle homologue 2 in medulloblastomas
    • Boon K., Eberhart C.G., Riggins G.J. Genomic amplification of orthodenticle homologue 2 in medulloblastomas. Cancer Res. 2005, 65:703-707.
    • (2005) Cancer Res. , vol.65 , pp. 703-707
    • Boon, K.1    Eberhart, C.G.2    Riggins, G.J.3
  • 18
    • 0034926798 scopus 로고    scopus 로고
    • Math5 is required for retinal ganglion cell and optic nerve formation
    • Brown N.L., Patel S., Brzezinski J., Glaser T. Math5 is required for retinal ganglion cell and optic nerve formation. Development 2001, 128:2497-2508.
    • (2001) Development , vol.128 , pp. 2497-2508
    • Brown, N.L.1    Patel, S.2    Brzezinski, J.3    Glaser, T.4
  • 19
    • 76449096558 scopus 로고    scopus 로고
    • Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development
    • Brzezinski J.A.t., Lamba D.A., Reh T.A. Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development. Development 2010, 137:619-629.
    • (2010) Development , vol.137 , pp. 619-629
    • Brzezinski, J.1    Lamba, D.A.2    Reh, T.A.3
  • 21
    • 84878869699 scopus 로고    scopus 로고
    • Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma
    • Cai Z., Tao C., Li H., Ladher R., Gotoh N., Feng G.S., Wang F., Zhang X. Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma. Development 2013, 140:2711-2723.
    • (2013) Development , vol.140 , pp. 2711-2723
    • Cai, Z.1    Tao, C.2    Li, H.3    Ladher, R.4    Gotoh, N.5    Feng, G.S.6    Wang, F.7    Zhang, X.8
  • 22
    • 0034892597 scopus 로고    scopus 로고
    • The Iroquois family of genes: from body building to neural patterning
    • Cavodeassi F., Modolell J., Gomez-Skarmeta J.L. The Iroquois family of genes: from body building to neural patterning. Development 2001, 128:2847-2855.
    • (2001) Development , vol.128 , pp. 2847-2855
    • Cavodeassi, F.1    Modolell, J.2    Gomez-Skarmeta, J.L.3
  • 24
    • 0036139494 scopus 로고    scopus 로고
    • Getting your Pax straight: Pax proteins in development and disease
    • Chi N., Epstein J.A. Getting your Pax straight: Pax proteins in development and disease. Trends Genet. 2002, 18:41-47.
    • (2002) Trends Genet. , vol.18 , pp. 41-47
    • Chi, N.1    Epstein, J.A.2
  • 27
    • 0035281520 scopus 로고    scopus 로고
    • Zebrafish genes rx1 and rx2 help define the region of forebrain that gives rise to retina
    • Chuang J.C., Raymond P.A. Zebrafish genes rx1 and rx2 help define the region of forebrain that gives rise to retina. Dev. Biol. 2001, 231:13-30.
    • (2001) Dev. Biol. , vol.231 , pp. 13-30
    • Chuang, J.C.1    Raymond, P.A.2
  • 28
    • 38849172494 scopus 로고    scopus 로고
    • Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina
    • Clark A.M., Yun S., Veien E.S., Wu Y.Y., Chow R.L., Dorsky R.I., Levine E.M. Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina. Brain Res. 2008, 1192:99-113.
    • (2008) Brain Res. , vol.1192 , pp. 99-113
    • Clark, A.M.1    Yun, S.2    Veien, E.S.3    Wu, Y.Y.4    Chow, R.L.5    Dorsky, R.I.6    Levine, E.M.7
  • 29
    • 0342393088 scopus 로고    scopus 로고
    • Expression of two novel mouse Iroquois homeobox genes during neurogenesis
    • Cohen D.R., Cheng C.W., Cheng S.H., Hui C.C. Expression of two novel mouse Iroquois homeobox genes during neurogenesis. Mech. Dev. 2000, 91:317-321.
    • (2000) Mech. Dev. , vol.91 , pp. 317-321
    • Cohen, D.R.1    Cheng, C.W.2    Cheng, S.H.3    Hui, C.C.4
  • 33
    • 13944276799 scopus 로고    scopus 로고
    • Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina
    • de Melo J., Du G., Fonseca M., Gillespie L.A., Turk W.J., Rubenstein J.L., Eisenstat D.D. Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina. Development 2005, 132:311-322.
    • (2005) Development , vol.132 , pp. 311-322
    • de Melo, J.1    Du, G.2    Fonseca, M.3    Gillespie, L.A.4    Turk, W.J.5    Rubenstein, J.L.6    Eisenstat, D.D.7
  • 35
    • 0037911441 scopus 로고    scopus 로고
    • Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina
    • de Melo J., Qiu X., Du G., Cristante L., Eisenstat D.D. Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina. J. Comp. Neurol. 2003, 461:187-204.
    • (2003) J. Comp. Neurol. , vol.461 , pp. 187-204
    • de Melo, J.1    Qiu, X.2    Du, G.3    Cristante, L.4    Eisenstat, D.D.5
  • 36
    • 39449122730 scopus 로고    scopus 로고
    • Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development
    • de Melo J., Zhou Q.P., Zhang Q., Zhang S., Fonseca M., Wigle J.T., Eisenstat D.D. Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development. Nucleic Acids Res. 2008, 36:872-884.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 872-884
    • de Melo, J.1    Zhou, Q.P.2    Zhang, Q.3    Zhang, S.4    Fonseca, M.5    Wigle, J.T.6    Eisenstat, D.D.7
  • 38
    • 3543018511 scopus 로고    scopus 로고
    • Organization of Iroquois genes in fish
    • Dildrop R., Ruther U. Organization of Iroquois genes in fish. Dev. Genes Evol. 2004, 214:267-276.
    • (2004) Dev. Genes Evol. , vol.214 , pp. 267-276
    • Dildrop, R.1    Ruther, U.2
  • 39
    • 65249183755 scopus 로고    scopus 로고
    • BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons
    • Ding Q., Chen H., Xie X., Libby R.T., Tian N., Gan L. BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons. J. Neurosci. Off. J. Soc. Neurosci. 2009, 29:3992-4003.
    • (2009) J. Neurosci. Off. J. Soc. Neurosci. , vol.29 , pp. 3992-4003
    • Ding, Q.1    Chen, H.2    Xie, X.3    Libby, R.T.4    Tian, N.5    Gan, L.6
  • 40
    • 15444378731 scopus 로고    scopus 로고
    • Transcriptional activity of the paired-like homeodomain proteins CHX10 and VSX1
    • Dorval K.M., Bobechko B.P., Ahmad K.F., Bremner R. Transcriptional activity of the paired-like homeodomain proteins CHX10 and VSX1. J. Biol. Chem. 2005, 280:10100-10108.
    • (2005) J. Biol. Chem. , vol.280 , pp. 10100-10108
    • Dorval, K.M.1    Bobechko, B.P.2    Ahmad, K.F.3    Bremner, R.4
  • 41
    • 0038561099 scopus 로고    scopus 로고
    • Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina
    • Dyer M.A., Livesey F.J., Cepko C.L., Oliver G. Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nat. Genet. 2003, 34:53-58.
    • (2003) Nat. Genet. , vol.34 , pp. 53-58
    • Dyer, M.A.1    Livesey, F.J.2    Cepko, C.L.3    Oliver, G.4
  • 42
    • 1842611572 scopus 로고    scopus 로고
    • Newborn horizontal cells migrate bi-directionally across the neuroepithelium during retinal development
    • Edqvist P.H., Hallbook F. Newborn horizontal cells migrate bi-directionally across the neuroepithelium during retinal development. Development 2004, 131:1343-1351.
    • (2004) Development , vol.131 , pp. 1343-1351
    • Edqvist, P.H.1    Hallbook, F.2
  • 45
  • 46
    • 84880397289 scopus 로고    scopus 로고
    • Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors
    • Emerson M.M., Surzenko N., Goetz J.J., Trimarchi J., Cepko C.L. Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors. Dev. Cell 2013, 26:59-72.
    • (2013) Dev. Cell , vol.26 , pp. 59-72
    • Emerson, M.M.1    Surzenko, N.2    Goetz, J.J.3    Trimarchi, J.4    Cepko, C.L.5
  • 47
    • 77956487180 scopus 로고    scopus 로고
    • Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system
    • Erickson T., French C.R., Waskiewicz A.J. Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system. Neural Dev. 2010, 5:22.
    • (2010) Neural Dev. , vol.5 , pp. 22
    • Erickson, T.1    French, C.R.2    Waskiewicz, A.J.3
  • 48
    • 33846258014 scopus 로고    scopus 로고
    • Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries
    • Erickson T., Scholpp S., Brand M., Moens C.B., Waskiewicz A.J. Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries. Dev. Biol. 2007, 301:504-517.
    • (2007) Dev. Biol. , vol.301 , pp. 504-517
    • Erickson, T.1    Scholpp, S.2    Brand, M.3    Moens, C.B.4    Waskiewicz, A.J.5
  • 55
    • 0036522977 scopus 로고    scopus 로고
    • The mouse Crx 5'-upstream transgene sequence directs cell-specific and developmentally regulated expression in retinal photoreceptor cells
    • Furukawa A., Koike C., Lippincott P., Cepko C.L., Furukawa T. The mouse Crx 5'-upstream transgene sequence directs cell-specific and developmentally regulated expression in retinal photoreceptor cells. J. Neurosci. Off. J. Soc. Neurosci. 2002, 22:1640-1647.
    • (2002) J. Neurosci. Off. J. Soc. Neurosci. , vol.22 , pp. 1640-1647
    • Furukawa, A.1    Koike, C.2    Lippincott, P.3    Cepko, C.L.4    Furukawa, T.5
  • 56
    • 0030979167 scopus 로고    scopus 로고
    • Rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina
    • Furukawa T., Kozak C.A., Cepko C.L. rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina. Proc. Natl. Acad. Sci. USA 1997, 94:3088-3093.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3088-3093
    • Furukawa, T.1    Kozak, C.A.2    Cepko, C.L.3
  • 57
    • 0032749223 scopus 로고    scopus 로고
    • Retinopathy and attenuated circadian entrainment in Crx-deficient mice
    • Furukawa T., Morrow E.M., Li T., Davis F.C., Cepko C.L. Retinopathy and attenuated circadian entrainment in Crx-deficient mice. Nat. Genet. 1999, 23:466-470.
    • (1999) Nat. Genet. , vol.23 , pp. 466-470
    • Furukawa, T.1    Morrow, E.M.2    Li, T.3    Davis, F.C.4    Cepko, C.L.5
  • 58
    • 0029863515 scopus 로고    scopus 로고
    • POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells
    • Gan L., Xiang M., Zhou L., Wagner D.S., Klein W.H., Nathans J. POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells. Proc. Natl. Acad. Sci. USA 1996, 93:3920-3925.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3920-3925
    • Gan, L.1    Xiang, M.2    Zhou, L.3    Wagner, D.S.4    Klein, W.H.5    Nathans, J.6
  • 61
    • 0036668276 scopus 로고    scopus 로고
    • Iroquois genes: genomic organization and function in vertebrate neural development
    • Gomez-Skarmeta J.L., Modolell J. Iroquois genes: genomic organization and function in vertebrate neural development. Curr. Opin. Genet. Dev. 2002, 12:403-408.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 403-408
    • Gomez-Skarmeta, J.L.1    Modolell, J.2
  • 63
    • 84880594849 scopus 로고    scopus 로고
    • Lhx2 balances progenitor maintenance with neurogenic output and promotes competence state progression in the developing retina
    • Gordon P.J., Yun S., Clark A.M., Monuki E.S., Murtaugh L.C., Levine E.M. Lhx2 balances progenitor maintenance with neurogenic output and promotes competence state progression in the developing retina. J. Neurosci. Off. J. Soc. Neurosci. 2013, 33:12197-12207.
    • (2013) J. Neurosci. Off. J. Soc. Neurosci. , vol.33 , pp. 12197-12207
    • Gordon, P.J.1    Yun, S.2    Clark, A.M.3    Monuki, E.S.4    Murtaugh, L.C.5    Levine, E.M.6
  • 64
    • 0037323862 scopus 로고    scopus 로고
    • Genetic rescue of cell number in a mouse model of microphthalmia: interactions between Chx10 and G1-phase cell cycle regulators
    • Green E.S., Stubbs J.L., Levine E.M. Genetic rescue of cell number in a mouse model of microphthalmia: interactions between Chx10 and G1-phase cell cycle regulators. Development 2003, 130:539-552.
    • (2003) Development , vol.130 , pp. 539-552
    • Green, E.S.1    Stubbs, J.L.2    Levine, E.M.3
  • 65
    • 0029002548 scopus 로고
    • The role of Pax-6 in eye and nasal development
    • Grindley J.C., Davidson D.R., Hill R.E. The role of Pax-6 in eye and nasal development. Development 1995, 121:1433-1442.
    • (1995) Development , vol.121 , pp. 1433-1442
    • Grindley, J.C.1    Davidson, D.R.2    Hill, R.E.3
  • 66
    • 0033386715 scopus 로고    scopus 로고
    • Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system
    • Hallonet M., Hollemann T., Pieler T., Gruss P. Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system. Genes Dev. 1999, 13:3106-3114.
    • (1999) Genes Dev. , vol.13 , pp. 3106-3114
    • Hallonet, M.1    Hollemann, T.2    Pieler, T.3    Gruss, P.4
  • 67
    • 0031827413 scopus 로고    scopus 로고
    • Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain
    • Hallonet M., Hollemann T., Wehr R., Jenkins N.A., Copeland N.G., Pieler T., Gruss P. Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain. Development 1998, 125:2599-2610.
    • (1998) Development , vol.125 , pp. 2599-2610
    • Hallonet, M.1    Hollemann, T.2    Wehr, R.3    Jenkins, N.A.4    Copeland, N.G.5    Pieler, T.6    Gruss, P.7
  • 70
    • 42149133155 scopus 로고    scopus 로고
    • Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development
    • Heine P., Dohle E., Bumsted-O'Brien K., Engelkamp D., Schulte D. Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development. Development 2008, 135:805-811.
    • (2008) Development , vol.135 , pp. 805-811
    • Heine, P.1    Dohle, E.2    Bumsted-O'Brien, K.3    Engelkamp, D.4    Schulte, D.5
  • 71
    • 38849100921 scopus 로고    scopus 로고
    • Regulation of photoreceptor gene expression by Crx-associated transcription factor network
    • Hennig A.K., Peng G.H., Chen S. Regulation of photoreceptor gene expression by Crx-associated transcription factor network. Brain Res. 2008, 1192:114-133.
    • (2008) Brain Res. , vol.1192 , pp. 114-133
    • Hennig, A.K.1    Peng, G.H.2    Chen, S.3
  • 72
    • 0026552381 scopus 로고
    • Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development
    • Higashijima S., Kojima T., Michiue T., Ishimaru S., Emori Y., Saigo K. Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development. Genes Dev. 1992, 6:50-60.
    • (1992) Genes Dev. , vol.6 , pp. 50-60
    • Higashijima, S.1    Kojima, T.2    Michiue, T.3    Ishimaru, S.4    Emori, Y.5    Saigo, K.6
  • 74
    • 0034141791 scopus 로고    scopus 로고
    • Functions of LIM-homeobox genes
    • Hobert O., Westphal H. Functions of LIM-homeobox genes. Trends Genet. 2000, 16:75-83.
    • (2000) Trends Genet. , vol.16 , pp. 75-83
    • Hobert, O.1    Westphal, H.2
  • 75
    • 13444270824 scopus 로고    scopus 로고
    • Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity
    • Horsford D.J., Nguyen M.T., Sellar G.C., Kothary R., Arnheiter H., McInnes R.R. Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development 2005, 132:177-187.
    • (2005) Development , vol.132 , pp. 177-187
    • Horsford, D.J.1    Nguyen, M.T.2    Sellar, G.C.3    Kothary, R.4    Arnheiter, H.5    McInnes, R.R.6
  • 76
    • 0033613942 scopus 로고    scopus 로고
    • OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6
    • Jacquemin P., Lannoy V.J., Rousseau G.G., Lemaigre F.P. OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6. J. Biol. Chem. 1999, 274:2665-2671.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2665-2671
    • Jacquemin, P.1    Lannoy, V.J.2    Rousseau, G.G.3    Lemaigre, F.P.4
  • 78
    • 77952377285 scopus 로고    scopus 로고
    • Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development
    • Katoh K., Omori Y., Onishi A., Sato S., Kondo M., Furukawa T. Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development. J. Neurosci. Off. J. Soc. Neurosci. 2010, 30:6515-6526.
    • (2010) J. Neurosci. Off. J. Soc. Neurosci. , vol.30 , pp. 6515-6526
    • Katoh, K.1    Omori, Y.2    Onishi, A.3    Sato, S.4    Kondo, M.5    Furukawa, T.6
  • 79
    • 84964959528 scopus 로고    scopus 로고
    • Lhx1 in the proximal region of the optic vesicle permits neural retina development in the chicken
    • Kawaue T., Okamoto M., Matsuyo A., Inoue J., Ueda Y., Tomonari S., Noji S., Ohuchi H. Lhx1 in the proximal region of the optic vesicle permits neural retina development in the chicken. Biol. Open 2012, 1:1083-1093.
    • (2012) Biol. Open , vol.1 , pp. 1083-1093
    • Kawaue, T.1    Okamoto, M.2    Matsuyo, A.3    Inoue, J.4    Ueda, Y.5    Tomonari, S.6    Noji, S.7    Ohuchi, H.8
  • 80
    • 33751113037 scopus 로고    scopus 로고
    • Hedgehog-regulated localization of Vax2 controls eye development
    • Kim J.W., Lemke G. Hedgehog-regulated localization of Vax2 controls eye development. Genes Dev. 2006, 20:2833-2847.
    • (2006) Genes Dev. , vol.20 , pp. 2833-2847
    • Kim, J.W.1    Lemke, G.2
  • 81
    • 0033977329 scopus 로고    scopus 로고
    • Both PCE-1/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression
    • Kimura A., Singh D., Wawrousek E.F., Kikuchi M., Nakamura M., Shinohara T. Both PCE-1/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression. J. Biol. Chem. 2000, 275:1152-1160.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1152-1160
    • Kimura, A.1    Singh, D.2    Wawrousek, E.F.3    Kikuchi, M.4    Nakamura, M.5    Shinohara, T.6
  • 83
    • 84868342584 scopus 로고    scopus 로고
    • Otx but not Mitf transcription factors are required for zebrafish retinal pigment epithelium development
    • Lane B.M., Lister J.A. Otx but not Mitf transcription factors are required for zebrafish retinal pigment epithelium development. PloS One 2012, 7:e49357.
    • (2012) PloS One , vol.7 , pp. e49357
    • Lane, B.M.1    Lister, J.A.2
  • 84
    • 0029841390 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain
    • Lemaigre F.P., Durviaux S.M., Truong O., Lannoy V.J., Hsuan J.J., Rousseau G.G. Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain. Proc. Natl. Acad. Sci. USA 1996, 93:9460-9464.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9460-9464
    • Lemaigre, F.P.1    Durviaux, S.M.2    Truong, O.3    Lannoy, V.J.4    Hsuan, J.J.5    Rousseau, G.G.6
  • 86
    • 0027968803 scopus 로고
    • Restricted expression of a new paired-class homeobox gene in normal and regenerating adult goldfish retina
    • Levine E.M., Hitchcock P.F., Glasgow E., Schechter N. Restricted expression of a new paired-class homeobox gene in normal and regenerating adult goldfish retina. J. Comp. Neurol. 1994, 348:596-606.
    • (1994) J. Comp. Neurol. , vol.348 , pp. 596-606
    • Levine, E.M.1    Hitchcock, P.F.2    Glasgow, E.3    Schechter, N.4
  • 87
    • 0030249695 scopus 로고    scopus 로고
    • Iroquois: a prepattern gene that controls the formation of bristles on the thorax of Drosophila
    • Leyns L., Gomez-Skarmeta J.L., Dambly-Chaudiere C. iroquois: a prepattern gene that controls the formation of bristles on the thorax of Drosophila. Mech. Dev. 1996, 59:63-72.
    • (1996) Mech. Dev. , vol.59 , pp. 63-72
    • Leyns, L.1    Gomez-Skarmeta, J.L.2    Dambly-Chaudiere, C.3
  • 88
    • 84898623945 scopus 로고    scopus 로고
    • Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells
    • Li R., Wu F., Ruonala R., Sapkota D., Hu Z., Mu X. Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells. PloS One 2014, 9:e92105.
    • (2014) PloS One , vol.9 , pp. e92105
    • Li, R.1    Wu, F.2    Ruonala, R.3    Sapkota, D.4    Hu, Z.5    Mu, X.6
  • 89
    • 4544294005 scopus 로고    scopus 로고
    • Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors
    • Li S., Mo Z., Yang X., Price S.M., Shen M.M., Xiang M. Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors. Neuron 2004, 43:795-807.
    • (2004) Neuron , vol.43 , pp. 795-807
    • Li, S.1    Mo, Z.2    Yang, X.3    Price, S.M.4    Shen, M.M.5    Xiang, M.6
  • 90
    • 0028048848 scopus 로고
    • Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer
    • Liu I.S., Chen J.D., Ploder L., Vidgen D., van der Kooy D., Kalnins V.I., McInnes R.R. Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer. Neuron 1994, 13:377-393.
    • (1994) Neuron , vol.13 , pp. 377-393
    • Liu, I.S.1    Chen, J.D.2    Ploder, L.3    Vidgen, D.4    van der Kooy, D.5    Kalnins, V.I.6    McInnes, R.R.7
  • 91
    • 0033836886 scopus 로고    scopus 로고
    • All Brn3 genes can promote retinal ganglion cell differentiation in the chick
    • Liu W., Khare S.L., Liang X., Peters M.A., Liu X., Cepko C.L., Xiang M. All Brn3 genes can promote retinal ganglion cell differentiation in the chick. Development 2000, 127:3237-3247.
    • (2000) Development , vol.127 , pp. 3237-3247
    • Liu, W.1    Khare, S.L.2    Liang, X.3    Peters, M.A.4    Liu, X.5    Cepko, C.L.6    Xiang, M.7
  • 92
    • 0034008333 scopus 로고    scopus 로고
    • Specific expression of the LIM/homeodomain protein Lim-1 in horizontal cells during retinogenesis
    • Liu W., Wang J.H., Xiang M. Specific expression of the LIM/homeodomain protein Lim-1 in horizontal cells during retinogenesis. Dev. Dyna. Off. Publ. Am. Assoc. Anatomists 2000, 217:320-325.
    • (2000) Dev. Dyna. Off. Publ. Am. Assoc. Anatomists , vol.217 , pp. 320-325
    • Liu, W.1    Wang, J.H.2    Xiang, M.3
  • 93
    • 0035257731 scopus 로고    scopus 로고
    • Vertebrate neural cell-fate determination: lessons from the retina
    • Livesey F.J., Cepko C.L. Vertebrate neural cell-fate determination: lessons from the retina. Nat. Rev. Neurosci. 2001, 2:109-118.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 109-118
    • Livesey, F.J.1    Cepko, C.L.2
  • 94
    • 33645518611 scopus 로고    scopus 로고
    • Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina
    • Livne-Bar I., Pacal M., Cheung M.C., Hankin M., Trogadis J., Chen D., Dorval K.M., Bremner R. Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina. Proc. Natl. Acad. Sci. USA 2006, 103:4988-4993.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 4988-4993
    • Livne-Bar, I.1    Pacal, M.2    Cheung, M.C.3    Hankin, M.4    Trogadis, J.5    Chen, D.6    Dorval, K.M.7    Bremner, R.8
  • 96
    • 0028864430 scopus 로고
    • Midline signalling is required for Pax gene regulation and patterning of the eyes
    • Macdonald R., Barth K.A., Xu Q., Holder N., Mikkola I., Wilson S.W. Midline signalling is required for Pax gene regulation and patterning of the eyes. Development 1995, 121:3267-3278.
    • (1995) Development , vol.121 , pp. 3267-3278
    • Macdonald, R.1    Barth, K.A.2    Xu, Q.3    Holder, N.4    Mikkola, I.5    Wilson, S.W.6
  • 97
    • 0030762576 scopus 로고    scopus 로고
    • The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain
    • Macdonald R., Scholes J., Strahle U., Brennan C., Holder N., Brand M., Wilson S.W. The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain. Development 1997, 124:2397-2408.
    • (1997) Development , vol.124 , pp. 2397-2408
    • Macdonald, R.1    Scholes, J.2    Strahle, U.3    Brennan, C.4    Holder, N.5    Brand, M.6    Wilson, S.W.7
  • 98
    • 0033118169 scopus 로고    scopus 로고
    • Pax genes and their role in organogenesis
    • (discussion 1709s-1710s)
    • Mansouri A., Goudreau G., Gruss P. Pax genes and their role in organogenesis. Cancer Res. 1999, 59:1707s-1709s. (discussion 1709s-1710s).
    • (1999) Cancer Res. , vol.59 , pp. 1707s-1709s
    • Mansouri, A.1    Goudreau, G.2    Gruss, P.3
  • 99
    • 44949168456 scopus 로고    scopus 로고
    • Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance
    • Manuel M., Pratt T., Liu M., Jeffery G., Price D.J. Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev. Biol. 2008, 8:59.
    • (2008) BMC Dev. Biol. , vol.8 , pp. 59
    • Manuel, M.1    Pratt, T.2    Liu, M.3    Jeffery, G.4    Price, D.J.5
  • 100
    • 0042700074 scopus 로고    scopus 로고
    • Transcriptional control of neuronal diversification in the retina
    • Marquardt T. Transcriptional control of neuronal diversification in the retina. Prog. Retinal Eye Res. 2003, 22:567-577.
    • (2003) Prog. Retinal Eye Res. , vol.22 , pp. 567-577
    • Marquardt, T.1
  • 104
    • 0031001710 scopus 로고    scopus 로고
    • The Rx homeobox gene is essential for vertebrate eye development
    • Mathers P.H., Grinberg A., Mahon K.A., Jamrich M. The Rx homeobox gene is essential for vertebrate eye development. Nature 1997, 387:603-607.
    • (1997) Nature , vol.387 , pp. 603-607
    • Mathers, P.H.1    Grinberg, A.2    Mahon, K.A.3    Jamrich, M.4
  • 105
    • 0028895055 scopus 로고
    • Mouse Otx2 functions in the formation and patterning of rostral head
    • Matsuo I., Kuratani S., Kimura C., Takeda N., Aizawa S. Mouse Otx2 functions in the formation and patterning of rostral head. Genes Dev. 1995, 9:2646-2658.
    • (1995) Genes Dev. , vol.9 , pp. 2646-2658
    • Matsuo, I.1    Kuratani, S.2    Kimura, C.3    Takeda, N.4    Aizawa, S.5
  • 106
    • 1642479166 scopus 로고    scopus 로고
    • Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells
    • Mo Z., Li S., Yang X., Xiang M. Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells. Development 2004, 131:1607-1618.
    • (2004) Development , vol.131 , pp. 1607-1618
    • Mo, Z.1    Li, S.2    Yang, X.3    Xiang, M.4
  • 107
    • 44349194164 scopus 로고    scopus 로고
    • Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2
    • Mu X., Fu X., Beremand P.D., Thomas T.L., Klein W.H. Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2. Proc. Natl. Acad. Sci. USA 2008, 105:6942-6947.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 6942-6947
    • Mu, X.1    Fu, X.2    Beremand, P.D.3    Thomas, T.L.4    Klein, W.H.5
  • 108
    • 0036333371 scopus 로고    scopus 로고
    • The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye
    • Mui S.H., Hindges R., O'Leary D.D., Lemke G., Bertuzzi S. The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development 2002, 129:797-804.
    • (2002) Development , vol.129 , pp. 797-804
    • Mui, S.H.1    Hindges, R.2    O'Leary, D.D.3    Lemke, G.4    Bertuzzi, S.5
  • 109
    • 18844396117 scopus 로고    scopus 로고
    • Vax genes ventralize the embryonic eye
    • Mui S.H., Kim J.W., Lemke G., Bertuzzi S. Vax genes ventralize the embryonic eye. Genes Dev. 2005, 19:1249-1259.
    • (2005) Genes Dev. , vol.19 , pp. 1249-1259
    • Mui, S.H.1    Kim, J.W.2    Lemke, G.3    Bertuzzi, S.4
  • 110
    • 84860261830 scopus 로고    scopus 로고
    • An essential role for Rax in retina and neuroendocrine system development
    • Muranishi Y., Terada K., Furukawa T. An essential role for Rax in retina and neuroendocrine system development. Dev. Growth Differ. 2012, 54:341-348.
    • (2012) Dev. Growth Differ. , vol.54 , pp. 341-348
    • Muranishi, Y.1    Terada, K.2    Furukawa, T.3
  • 112
    • 61349196787 scopus 로고    scopus 로고
    • Retinal homeobox 1 is required for retinal neurogenesis and photoreceptor differentiation in embryonic zebrafish
    • Nelson S.M., Park L., Stenkamp D.L. Retinal homeobox 1 is required for retinal neurogenesis and photoreceptor differentiation in embryonic zebrafish. Dev. Biol. 2009, 328:24-39.
    • (2009) Dev. Biol. , vol.328 , pp. 24-39
    • Nelson, S.M.1    Park, L.2    Stenkamp, D.L.3
  • 113
    • 0033828906 scopus 로고    scopus 로고
    • Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF
    • Nguyen M., Arnheiter H. Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF. Development 2000, 127:3581-3591.
    • (2000) Development , vol.127 , pp. 3581-3591
    • Nguyen, M.1    Arnheiter, H.2
  • 114
  • 115
    • 0027170576 scopus 로고
    • Evolution and role of Pax genes
    • Noll M. Evolution and role of Pax genes. Curr. Opin. Genet. Dev. 1993, 3:595-605.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 595-605
    • Noll, M.1
  • 116
    • 0025125431 scopus 로고
    • Spatially and temporally restricted expression of Pax2 during murine neurogenesis
    • Nornes H.O., Dressler G.R., Knapik E.W., Deutsch U., Gruss P. Spatially and temporally restricted expression of Pax2 during murine neurogenesis. Development 1990, 109:797-809.
    • (1990) Development , vol.109 , pp. 797-809
    • Nornes, H.O.1    Dressler, G.R.2    Knapik, E.W.3    Deutsch, U.4    Gruss, P.5
  • 117
    • 38849193368 scopus 로고    scopus 로고
    • Regulation of retinal cell fate specification by multiple transcription factors
    • Ohsawa R., Kageyama R. Regulation of retinal cell fate specification by multiple transcription factors. Brain Res. 2008, 1192:90-98.
    • (2008) Brain Res. , vol.1192 , pp. 90-98
    • Ohsawa, R.1    Kageyama, R.2
  • 118
    • 79955936417 scopus 로고    scopus 로고
    • Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina
    • Omori Y., Katoh K., Sato S., Muranishi Y., Chaya T., Onishi A., Minami T., Fujikado T., Furukawa T. Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina. PloS One 2011, 6:e19685.
    • (2011) PloS One , vol.6 , pp. e19685
    • Omori, Y.1    Katoh, K.2    Sato, S.3    Muranishi, Y.4    Chaya, T.5    Onishi, A.6    Minami, T.7    Fujikado, T.8    Furukawa, T.9
  • 120
    • 8344226058 scopus 로고    scopus 로고
    • Magnitude of binocular vision controlled by islet-2 repression of a genetic program that specifies laterality of retinal axon pathfinding
    • Pak W., Hindges R., Lim Y.S., Pfaff S.L., O'Leary D.D. Magnitude of binocular vision controlled by islet-2 repression of a genetic program that specifies laterality of retinal axon pathfinding. Cell 2004, 119:567-578.
    • (2004) Cell , vol.119 , pp. 567-578
    • Pak, W.1    Hindges, R.2    Lim, Y.S.3    Pfaff, S.L.4    O'Leary, D.D.5
  • 121
    • 46749136875 scopus 로고    scopus 로고
    • ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells
    • Pan L., Deng M., Xie X., Gan L. ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells. Development 2008, 135:1981-1990.
    • (2008) Development , vol.135 , pp. 1981-1990
    • Pan, L.1    Deng, M.2    Xie, X.3    Gan, L.4
  • 122
    • 14844353279 scopus 로고    scopus 로고
    • Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis
    • Pan L., Yang Z., Feng L., Gan L. Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis. Development 2005, 132:703-712.
    • (2005) Development , vol.132 , pp. 703-712
    • Pan, L.1    Yang, Z.2    Feng, L.3    Gan, L.4
  • 124
    • 0036796883 scopus 로고    scopus 로고
    • Developmental functions of the Distal-less/Dlx homeobox genes
    • Panganiban G., Rubenstein J.L. Developmental functions of the Distal-less/Dlx homeobox genes. Development 2002, 129:4371-4386.
    • (2002) Development , vol.129 , pp. 4371-4386
    • Panganiban, G.1    Rubenstein, J.L.2
  • 125
    • 0033782832 scopus 로고    scopus 로고
    • Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development
    • Peters T., Dildrop R., Ausmeier K., Ruther U. Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development. Genome Res. 2000, 10:1453-1462.
    • (2000) Genome Res. , vol.10 , pp. 1453-1462
    • Peters, T.1    Dildrop, R.2    Ausmeier, K.3    Ruther, U.4
  • 126
    • 0030051923 scopus 로고    scopus 로고
    • Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation
    • Pfaff S.L., Mendelsohn M., Stewart C.L., Edlund T., Jessell T.M. Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Cell 1996, 84:309-320.
    • (1996) Cell , vol.84 , pp. 309-320
    • Pfaff, S.L.1    Mendelsohn, M.2    Stewart, C.L.3    Edlund, T.4    Jessell, T.M.5
  • 128
    • 34248398290 scopus 로고    scopus 로고
    • The proneural determinant MASH1 regulates forebrain Dlx1/2 expression through the I12b intergenic enhancer
    • Poitras L., Ghanem N., Hatch G., Ekker M. The proneural determinant MASH1 regulates forebrain Dlx1/2 expression through the I12b intergenic enhancer. Development 2007, 134:1755-1765.
    • (2007) Development , vol.134 , pp. 1755-1765
    • Poitras, L.1    Ghanem, N.2    Hatch, G.3    Ekker, M.4
  • 130
    • 41549112585 scopus 로고    scopus 로고
    • A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors
    • Qiu F., Jiang H., Xiang M. A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors. J. Neurosci. Off. J. Soc. Neurosci. 2008, 28:3392-3403.
    • (2008) J. Neurosci. Off. J. Soc. Neurosci. , vol.28 , pp. 3392-3403
    • Qiu, F.1    Jiang, H.2    Xiang, M.3
  • 132
    • 0027965633 scopus 로고
    • Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans
    • Quiring R., Walldorf U., Kloter U., Gehring W.J. Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 1994, 265:785-789.
    • (1994) Science , vol.265 , pp. 785-789
    • Quiring, R.1    Walldorf, U.2    Kloter, U.3    Gehring, W.J.4
  • 134
    • 33846782978 scopus 로고    scopus 로고
    • Functions of BarH transcription factors during embryonic development
    • Reig G., Cabrejos M.E., Concha M.L. Functions of BarH transcription factors during embryonic development. Dev. Biol. 2007, 302:367-375.
    • (2007) Dev. Biol. , vol.302 , pp. 367-375
    • Reig, G.1    Cabrejos, M.E.2    Concha, M.L.3
  • 137
    • 3042633465 scopus 로고    scopus 로고
    • Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter
    • Rowan S., Cepko C.L. Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter. Dev. Biol. 2004, 271:388-402.
    • (2004) Dev. Biol. , vol.271 , pp. 388-402
    • Rowan, S.1    Cepko, C.L.2
  • 138
    • 8444237405 scopus 로고    scopus 로고
    • Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10
    • Rowan S., Chen C.M., Young T.L., Fisher D.E., Cepko C.L. Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development 2004, 131:5139-5152.
    • (2004) Development , vol.131 , pp. 5139-5152
    • Rowan, S.1    Chen, C.M.2    Young, T.L.3    Fisher, D.E.4    Cepko, C.L.5
  • 140
    • 0036848614 scopus 로고    scopus 로고
    • Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain
    • Ryter J.M., Doe C.Q., Matthews B.W. Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain. Structure. 2002, 10:1541-1549.
    • (2002) Structure. , vol.10 , pp. 1541-1549
    • Ryter, J.M.1    Doe, C.Q.2    Matthews, B.W.3
  • 141
    • 0028060189 scopus 로고
    • The LIM domain: a new structural motif found in zinc-finger-like proteins
    • Sanchez-Garcia I., Rabbitts T.H. The LIM domain: a new structural motif found in zinc-finger-like proteins. Trends Genet. 1994, 10:315-320.
    • (1994) Trends Genet. , vol.10 , pp. 315-320
    • Sanchez-Garcia, I.1    Rabbitts, T.H.2
  • 143
    • 0030581164 scopus 로고    scopus 로고
    • Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities
    • Schedl A., Ross A., Lee M., Engelkamp D., Rashbass P., van Heyningen V., Hastie N.D. Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell 1996, 86:71-82.
    • (1996) Cell , vol.86 , pp. 71-82
    • Schedl, A.1    Ross, A.2    Lee, M.3    Engelkamp, D.4    Rashbass, P.5    van Heyningen, V.6    Hastie, N.D.7
  • 145
    • 0033231291 scopus 로고    scopus 로고
    • Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map
    • Schulte D., Furukawa T., Peters M.A., Kozak C.A., Cepko C.L. Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map. Neuron 1999, 24:541-553.
    • (1999) Neuron , vol.24 , pp. 541-553
    • Schulte, D.1    Furukawa, T.2    Peters, M.A.3    Kozak, C.A.4    Cepko, C.L.5
  • 146
    • 0033738874 scopus 로고    scopus 로고
    • Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6
    • Schwarz M., Cecconi F., Bernier G., Andrejewski N., Kammandel B., Wagner M., Gruss P. Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6. Development 2000, 127:4325-4334.
    • (2000) Development , vol.127 , pp. 4325-4334
    • Schwarz, M.1    Cecconi, F.2    Bernier, G.3    Andrejewski, N.4    Kammandel, B.5    Wagner, M.6    Gruss, P.7
  • 149
    • 0027260743 scopus 로고
    • A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo
    • Simeone A., Acampora D., Mallamaci A., Stornaiuolo A., D'Apice M.R., Nigro V., Boncinelli E. A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J. 1993, 12:2735-2747.
    • (1993) EMBO J. , vol.12 , pp. 2735-2747
    • Simeone, A.1    Acampora, D.2    Mallamaci, A.3    Stornaiuolo, A.4    D'Apice, M.R.5    Nigro, V.6    Boncinelli, E.7
  • 150
    • 0029846335 scopus 로고    scopus 로고
    • A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo
    • Smith S.T., Jaynes J.B. A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo. Development 1996, 122:3141-3150.
    • (1996) Development , vol.122 , pp. 3141-3150
    • Smith, S.T.1    Jaynes, J.B.2
  • 155
    • 77954879972 scopus 로고    scopus 로고
    • Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina
    • Swaroop A., Kim D., Forrest D. Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina. Nat. Rev. Neurosci. 2010, 11:563-576.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 563-576
    • Swaroop, A.1    Kim, D.2    Forrest, D.3
  • 156
    • 58149383817 scopus 로고    scopus 로고
    • OTX2 loss of function mutation causes anophthalmia and combined pituitary hormone deficiency with a small anterior and ectopic posterior pituitary
    • Tajima T., Ohtake A., Hoshino M., Amemiya S., Sasaki N., Ishizu K., Fujieda K. OTX2 loss of function mutation causes anophthalmia and combined pituitary hormone deficiency with a small anterior and ectopic posterior pituitary. J. Clin. Endocrinol. Metab. 2009, 94:314-319.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 314-319
    • Tajima, T.1    Ohtake, A.2    Hoshino, M.3    Amemiya, S.4    Sasaki, N.5    Ishizu, K.6    Fujieda, K.7
  • 157
    • 0028277885 scopus 로고
    • Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected]
    • Tanizawa Y., Riggs A.C., Dagogo-Jack S., Vaxillaire M., Froguel P., Liu L., Donis-Keller H., Permutt M.A. Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected]. Diabetes 1994, 43:935-941.
    • (1994) Diabetes , vol.43 , pp. 935-941
    • Tanizawa, Y.1    Riggs, A.C.2    Dagogo-Jack, S.3    Vaxillaire, M.4    Froguel, P.5    Liu, L.6    Donis-Keller, H.7    Permutt, M.A.8
  • 158
    • 33644983711 scopus 로고    scopus 로고
    • Nucleosome regulator Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1
    • Terada K., Kitayama A., Kanamoto T., Ueno N., Furukawa T. Nucleosome regulator Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1. Dev. Biol. 2006, 291:398-412.
    • (2006) Dev. Biol. , vol.291 , pp. 398-412
    • Terada, K.1    Kitayama, A.2    Kanamoto, T.3    Ueno, N.4    Furukawa, T.5
  • 159
    • 60549094394 scopus 로고    scopus 로고
    • The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation
    • Tetreault N., Champagne M.P., Bernier G. The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation. Dev. Biol. 2009, 327:541-550.
    • (2009) Dev. Biol. , vol.327 , pp. 541-550
    • Tetreault, N.1    Champagne, M.P.2    Bernier, G.3
  • 160
    • 0029953417 scopus 로고    scopus 로고
    • Pax2 contributes to inner ear patterning and optic nerve trajectory
    • Torres M., Gomez-Pardo E., Gruss P. Pax2 contributes to inner ear patterning and optic nerve trajectory. Development 1996, 122:3381-3391.
    • (1996) Development , vol.122 , pp. 3381-3391
    • Torres, M.1    Gomez-Pardo, E.2    Gruss, P.3
  • 161
    • 0023182049 scopus 로고
    • A common progenitor for neurons and glia persists in rat retina late in development
    • Turner D.L., Cepko C.L. A common progenitor for neurons and glia persists in rat retina late in development. Nature 1987, 328:131-136.
    • (1987) Nature , vol.328 , pp. 131-136
    • Turner, D.L.1    Cepko, C.L.2
  • 162
    • 25444528475 scopus 로고    scopus 로고
    • PAX6 mutations: genotype-phenotype correlations
    • Tzoulaki I., White I.M., Hanson I.M. PAX6 mutations: genotype-phenotype correlations. BMC Genet. 2005, 6:27.
    • (2005) BMC Genet. , vol.6 , pp. 27
    • Tzoulaki, I.1    White, I.M.2    Hanson, I.M.3
  • 164
    • 31744436876 scopus 로고    scopus 로고
    • Divergence of hedgehog signal transduction mechanism between Drosophila and mammals
    • Varjosalo M., Li S.P., Taipale J. Divergence of hedgehog signal transduction mechanism between Drosophila and mammals. Dev. Cell 2006, 10:177-186.
    • (2006) Dev. Cell , vol.10 , pp. 177-186
    • Varjosalo, M.1    Li, S.P.2    Taipale, J.3
  • 167
    • 0026340588 scopus 로고
    • Pax-6, a murine paired box gene, is expressed in the developing CNS
    • Walther C., Gruss P. Pax-6, a murine paired box gene, is expressed in the developing CNS. Development 1991, 113:1435-1449.
    • (1991) Development , vol.113 , pp. 1435-1449
    • Walther, C.1    Gruss, P.2
  • 169
    • 0035176828 scopus 로고    scopus 로고
    • Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning
    • Waskiewicz A.J., Rikhof H.A., Hernandez R.E., Moens C.B. Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning. Development 2001, 128:4139-4151.
    • (2001) Development , vol.128 , pp. 4139-4151
    • Waskiewicz, A.J.1    Rikhof, H.A.2    Hernandez, R.E.3    Moens, C.B.4
  • 170
    • 0036850345 scopus 로고    scopus 로고
    • Eliminating zebrafish pbx proteins reveals a hindbrain ground state
    • Waskiewicz A.J., Rikhof H.A., Moens C.B. Eliminating zebrafish pbx proteins reveals a hindbrain ground state. Dev. Cell 2002, 3:723-733.
    • (2002) Dev. Cell , vol.3 , pp. 723-733
    • Waskiewicz, A.J.1    Rikhof, H.A.2    Moens, C.B.3
  • 172
    • 0023869524 scopus 로고
    • Multipotent precursors can give rise to all major cell types of the frog retina
    • Wetts R., Fraser S.E. Multipotent precursors can give rise to all major cell types of the frog retina. Science 1988, 239:1142-1145.
    • (1988) Science , vol.239 , pp. 1142-1145
    • Wetts, R.1    Fraser, S.E.2
  • 173
    • 0033018615 scopus 로고    scopus 로고
    • Prox1 function is crucial for mouse lens-fibre elongation
    • Wigle J.T., Chowdhury K., Gruss P., Oliver G. Prox1 function is crucial for mouse lens-fibre elongation. Nat. Genet. 1999, 21:318-322.
    • (1999) Nat. Genet. , vol.21 , pp. 318-322
    • Wigle, J.T.1    Chowdhury, K.2    Gruss, P.3    Oliver, G.4
  • 174
    • 38949214667 scopus 로고    scopus 로고
    • Homeobox genes in vertebrate forebrain development and disease
    • Wigle J.T., Eisenstat D.D. Homeobox genes in vertebrate forebrain development and disease. Clin. Genet. 2008, 73:212-226.
    • (2008) Clin. Genet. , vol.73 , pp. 212-226
    • Wigle, J.T.1    Eisenstat, D.D.2
  • 176
    • 84863393076 scopus 로고    scopus 로고
    • Onecut 1 and Onecut 2 are potential regulators of mouse retinal development
    • Wu F., Sapkota D., Li R., Mu X. Onecut 1 and Onecut 2 are potential regulators of mouse retinal development. J. Comp. Neurol. 2012, 520:952-969.
    • (2012) J. Comp. Neurol. , vol.520 , pp. 952-969
    • Wu, F.1    Sapkota, D.2    Li, R.3    Mu, X.4
  • 179
    • 0029964874 scopus 로고    scopus 로고
    • Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling
    • Xiang M., Gan L., Zhou L., Klein W.H., Nathans J. Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling. Proc. Natl. Acad. Sci. USA 1996, 93:11950-11955.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11950-11955
    • Xiang, M.1    Gan, L.2    Zhou, L.3    Klein, W.H.4    Nathans, J.5
  • 180
    • 0029025828 scopus 로고
    • The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons
    • Xiang M., Zhou L., Macke J.P., Yoshioka T., Hendry S.H., Eddy R.L., Shows T.B., Nathans J. The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons. J Neurosci. Off. J. Soc. Neurosci. 1995, 15:4762-4785.
    • (1995) J Neurosci. Off. J. Soc. Neurosci. , vol.15 , pp. 4762-4785
    • Xiang, M.1    Zhou, L.2    Macke, J.P.3    Yoshioka, T.4    Hendry, S.H.5    Eddy, R.L.6    Shows, T.B.7    Nathans, J.8
  • 181
    • 0021830601 scopus 로고
    • Cell differentiation in the retina of the mouse
    • Young R.W. Cell differentiation in the retina of the mouse. Anat. Rec. 1985, 212:199-205.
    • (1985) Anat. Rec. , vol.212 , pp. 199-205
    • Young, R.W.1
  • 182
    • 17044383349 scopus 로고    scopus 로고
    • Structural basis of Prospero-DNA interaction: implications for transcription regulation in developing cells
    • Yousef M.S., Matthews B.W. Structural basis of Prospero-DNA interaction: implications for transcription regulation in developing cells. Structure 2005, 13:601-607.
    • (2005) Structure , vol.13 , pp. 601-607
    • Yousef, M.S.1    Matthews, B.W.2
  • 184
    • 85028133592 scopus 로고    scopus 로고
    • Transcriptional regulation of the POU homeobox gene Brn3b by Dlx1 and Dlx2 is required for late-born retinal ganglion cell differentiation in the developing vertebrate retina, in revision.
    • Zhang Q, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Wigle JT, Schuurmans C, Eisenstat DD. Transcriptional regulation of the POU homeobox gene Brn3b by Dlx1 and Dlx2 is required for late-born retinal ganglion cell differentiation in the developing vertebrate retina, in revision.
    • Zhang, Q.1    Cheng, S.2    Dixit, R.3    Zhang, S.4    de Melo, J.5    Mu, X.6    Klein, W.H.7    Wigle, J.T.8    Schuurmans, C.9    Eisenstat, D.D.10
  • 185
    • 0034490095 scopus 로고    scopus 로고
    • Function of Rx, but not Pax6, is essential for the formation of retinal progenitor cells in mice
    • Transcriptional regulation of the POU homeobox gene Brn3b by Dlx1 and Dlx2 is required for late-born retinal ganglion cell differentiation in the developing vertebrate retina, in revision.Zhang L Mathers P.H. Jamrich M.
    • Zhang Q, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Wigle JT, Schuurmans C, Eisenstat DD.Transcriptional regulation of the POU homeobox gene Brn3b by Dlx1 and Dlx2 is required for late-born retinal ganglion cell differentiation in the developing vertebrate retina, in revision.Zhang L., Mathers P.H., Jamrich M. Function of Rx, but not Pax6, is essential for the formation of retinal progenitor cells in mice. Genesis 2000, 28:135-142.
    • (2000) Genesis , vol.28 , pp. 135-142
    • Zhang, Q.1    Cheng, S.2    Dixit, R.3    Zhang, S.4    de Melo, J.5    Mu, X.6    Klein, W.H.7    Wigle, J.T.8    Schuurmans, C.9    Eisenstat, D.D.10
  • 187
    • 84866948611 scopus 로고    scopus 로고
    • Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding
    • Zou C., Levine E.M. Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding. PLoS Genet. 2012, 8:e1002924.
    • (2012) PLoS Genet. , vol.8 , pp. e1002924
    • Zou, C.1    Levine, E.M.2
  • 188
    • 0242635513 scopus 로고    scopus 로고
    • Specification of the vertebrate eye by a network of eye field transcription factors
    • Zuber M.E., Gestri G., Viczian A.S., Barsacchi G., Harris W.A. Specification of the vertebrate eye by a network of eye field transcription factors. Development 2003, 130:5155-5167.
    • (2003) Development , vol.130 , pp. 5155-5167
    • Zuber, M.E.1    Gestri, G.2    Viczian, A.S.3    Barsacchi, G.4    Harris, W.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.