All Brn3 genes can promote retinal ganglion cell differentiation in the chick

Development

Volumn 127, Issue 15, 2000, Pages 3237-3247

  Liu, W ^a   Khare, S L ^a   Liang, X ^a   Peters, M A ^a   Liu, X ^a   Cepko, C L ^a   Xiang, M ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Brn3; Chick; POU domain; Retinal ganglion cell; Transcription factor

Indexed keywords

TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; CELL MATURATION; CHICK EMBRYO; CHICKEN; CONTROLLED STUDY; DNA BINDING; EMBRYO; GENE DISRUPTION; GENE EXPRESSION; IN VIVO STUDY; MITOSIS; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; RETINA DEVELOPMENT; RETINA GANGLION CELL; STEM CELL; SURVIVAL; TRANSACTIVATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL MOVEMENT; CHICK EMBRYO; DNA; DNA-BINDING PROTEINS; HUMANS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RETINA; RETINAL GANGLION CELLS; STEM CELLS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR BRN-3; TRANSCRIPTION FACTOR BRN-3A; TRANSCRIPTION FACTOR BRN-3B; TRANSCRIPTION FACTOR BRN-3C; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA; GALLUS GALLUS;

EID: 0033836886     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. A temporally regulated, diffusible activity is required for rod photoreceptor development in vitro
2. Placodal origin of Brn-3-expressing cranial sensory neurons
3. Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch
4. Lineage-specific regulators couple cell lineage asymmetry to the transcription of the Caenorhabditis elegans POU gene unc-86 during neurogenesis
5. A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts
6. Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death
7. The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site
8. The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells
9. POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element
10. A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program
11. The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates
12. Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development
13. Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression/transduction in the chick embryo
14. The unc-86 gene product couples cell lineage and cell identity in C. elegans
15. The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors
16. POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification
17. POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells
18. Brn-3.0: A POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs
19. Transient production of proteins using an adenovirus transformed cell line
20. POU domain factors of the Brn-3 class recognize functional DNA elements which are distinctive, symmetrical, and highly conserved in evolution
21. A series of normal stages in the development of the chick embryos
22. Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene
23. Xath5 participates in a network of bHLH genes in the developing Xenopus retina
24. Identification of a chicken homologue in the Brn-3 subfamily of POU- transcription factors
25. Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons
26. Manipulating gene expression with replication-competent retroviruses
27. The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain
28. Myogenin gene disruption results in perinatal lethality because of severe muscle defect
29. Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo
30. X-ngnr-1 and Xath3 promote ectopic expression of sensory neuron markers in the neural ectoderm and have distinct inducing properties in the retina
31. Spatial and temporal patterns of neurogenesis in the chick retina
32. Regulation of herpes simplex virus (HSV) immediate-early gene expression during lytic and latent infection
33. Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis
34. Regulation of cytomegalovirus gene expression: Alpha and beta promoters are transactivated by viral functions in permissive human fibroblasts
35. Mouse Brn-3 family of POU transcription factors: A new aminoterminal domain is crucial for the oncogenic activity of Brn-3a
36. Short isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif binding
37. Autoregulatory sequences are revealed by complex stability screening of the mouse brn-3.0 locus
38. A common progenitor for neurons and glia persists in rat retina late in development
39. Lineage-independent determination of cell type in the embryonic mouse retina
40. Similar DNA recognition properties of alternatively spliced Drosophila POU factors
41. Brn-3.2: A Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid
42. Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans
43. Myogenin can substitute for Myf5 in promoting myogenesis but less efficiently
44. Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin
45. Novel cell lines display properties of nociceptive sensory neurons
46. Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors
47. Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling
48. Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development
49. Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells
50. Brn-3b: A POU domain gene expressed in a subset of retinal ganglion cells
51. The Brn-3 family of POU-domain factors: Primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons
52. Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate
53. Cell differentiation in the retina of the mouse