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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 899, Issue , 2012, Pages 127-134

Direct pharmacokinetic analysis of puqietinone by in vivo microdialysis sampling and turbulent-flow chromatography coupled with liquid chromatography-mass spectrometry

(8) Xin, Gui Zhong a Cao, Liu a Shi, Zi Qi a Li, Hui Jun a Wen, Xiao Dong a Chen, Jun a Qi, Lian Wen a Li, Ping a

a CHINA PHARMACEUTICAL UNIVERSITY (China)

Author keywords

Desalting; Mass spectrometry; Microdialysis; Pharmacokinetic; Puqietinone; Turbulent flow chromatography

Indexed keywords

ACCURACY AND PRECISION; ANALYTES; AQUEOUS PHASE; BIO-SAMPLES; BIOANALYTICAL; DIVERTER VALVES; FAST-LC; FRITILLARIA; IN-VIVO; INJECTION VOLUME; INTRAVENOUS ADMINISTRATION; LIMIT OF QUANTIFICATIONS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MASS SPECTROMETRY ANALYSIS; MATRIX EFFECTS; MICRO-DIALYSIS; NOVEL STRATEGIES; ONE STEP; OPTIMIZATION PROCEDURES; PHARMACOKINETIC ANALYSIS; PHARMACOKINETIC STUDIES; PRE-CONCENTRATION; PUQIETINONE; SAMPLE PRETREATMENT; STANDARD CURVES;

DESALINATION; DIALYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SALT REMOVAL;

PHARMACOKINETICS;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ALKALOID DERIVATIVE; PUQIETINONE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; FLOW RATE; IN VIVO STUDY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; PROCESS DESIGN; PROCESS OPTIMIZATION; RAT; TURBULENT FLOW CHROMATOGRAPHY; VALIDATION PROCESS;

ALKALOIDS; ANIMALS; CHROMATOGRAPHY, LIQUID; FRITILLARIA; MALE; MASS SPECTROMETRY; MICRODIALYSIS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY;

FRITILLARIA PUQIENSIS; RATTUS;

EID: 84862123334 PISSN: 15700232 EISSN: 1873376X Source Type: Journal
DOI: 10.1016/j.jchromb.2012.05.012 Document Type: Article

Times cited : (11)

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