Sensitive determination of kaempferol in rat plasma by high-performance liquid chromatography with chemiluminescence detection and application to a pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 29, 2009, Pages 3595-3600

  Zhang, Qunlin ^a   Zhang, Yunjing ^a   Zhang, Zhongtang ^a   Lu, Zidong ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Cerium(IV); Chemiluminescence; High performance liquid chromatography; Kaempferol; Pharmacokinetics; Rat plasma; Rhodamine 6G

Indexed keywords

BODYWEIGHT; CHEMILUMINESCENCE DETECTION; DETECTION LIMITS; INTERNAL STANDARDS; ISOCRATIC ELUTION; KAEMPFEROL; MOBILE PHASE; ORAL ADMINISTRATION; PHARMACOKINETIC PARAMETERS; PHARMACOKINETIC STUDIES; PLASMA SAMPLES; PROTEIN PRECIPITATION; RAT PLASMA; RHODAMINE 6G; SAMPLE PREPARATION METHODS; SENSITIVE METHOD; WIDE-LINEAR RANGE;

ACIDS; CERIUM; CHEMILUMINESCENCE; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGHT EMISSION; LIGHT MEASUREMENT; LIQUIDS; METHANOL; PHARMACOKINETICS; PHOSPHORIC ACID; PLASMA (HUMAN); PLASMAS;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

CERIUM; ISORHAMNETIN; KAEMPFEROL; RHODAMINE 6G; SULFURIC ACID;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CHEMOLUMINESCENCE; CHICKEN; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE COMPARISON; FEMALE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT; SPECIES COMPARISON; SWINE; ULTRAVIOLET SPECTROSCOPY; VALIDATION STUDY;

ANIMALS; CHEMILUMINESCENT MEASUREMENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; KAEMPFEROLS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS;

RATTUS;

EID: 72049117129     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.08.046     Document Type: Article

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