Change or die: Targeting adaptive signaling to kinase inhibition in cancer cells

Biochemical Pharmacology

Volumn 91, Issue 4, 2014, Pages 417-425

  Rebecca, Vito W ^a   Smalley, Keiran S M ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

BRAF; Melanoma; NRAS; Phosphoproteomics; Signaling

Indexed keywords

ADAPTOR PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; PROTEIN SH3; PROTEIN TYROSINE KINASE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

AUTOPHOSPHORYLATION; CANCER CELL; CANCER GROWTH; CELL METABOLISM; CELL SURVIVAL; DRUG TREATMENT FAILURE; ENZYME ACTIVE SITE; EXTRACELLULAR MATRIX; FEEDBACK SYSTEM; GENE FUNCTION; HOMEOSTASIS; HUMAN; INTRACELLULAR SIGNALING; LIGAND BINDING; MOLECULARLY TARGETED THERAPY; NEGATIVE FEEDBACK; NONHUMAN; ONCOGENE; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; ADAPTATION; ENZYMOLOGY; METABOLISM; NEOPLASM; PATHOLOGY;

ADAPTATION, PHYSIOLOGICAL; HUMANS; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 84921628212     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.07.031     Document Type: Note

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