-
1
-
-
79952463034
-
Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment
-
Romero-Gomez M, Eslam M, Ruiz A, Maraver M. Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment. Liver Int 2011;31:443-460.
-
(2011)
Liver Int
, vol.31
, pp. 443-460
-
-
Romero-Gomez, M.1
Eslam, M.2
Ruiz, A.3
Maraver, M.4
-
2
-
-
78049265857
-
Host genetic basis for hepatitis C virus clearance: a role for blood collection centers
-
Selvarajah S, Tobler LH, Simmons G, Busch MP. Host genetic basis for hepatitis C virus clearance: a role for blood collection centers. Curr Opin Hematol 2010;17:550-557.
-
(2010)
Curr Opin Hematol
, vol.17
, pp. 550-557
-
-
Selvarajah, S.1
Tobler, L.H.2
Simmons, G.3
Busch, M.P.4
-
3
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
Ge D, Fellay J, Thompson AJ, Simon JS, Shianna KV, Urban TJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009;461:399-401.
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.J.3
Simon, J.S.4
Shianna, K.V.5
Urban, T.J.6
-
4
-
-
70349548852
-
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
-
Suppiah V, Moldovan M, Ahlenstiel G, Berg T, Weltman M, Abate ML, et al. IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet 2009;41:1100-1104.
-
(2009)
Nat Genet
, vol.41
, pp. 1100-1104
-
-
Suppiah, V.1
Moldovan, M.2
Ahlenstiel, G.3
Berg, T.4
Weltman, M.5
Abate, M.L.6
-
5
-
-
70349533037
-
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
-
Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N, et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet 2009;41:1105-1109.
-
(2009)
Nat Genet
, vol.41
, pp. 1105-1109
-
-
Tanaka, Y.1
Nishida, N.2
Sugiyama, M.3
Kurosaki, M.4
Matsuura, K.5
Sakamoto, N.6
-
6
-
-
70349966196
-
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
-
Thomas DL, Thio CL, Martin MP, Qi Y, Ge D, O'Huigin C, et al. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature 2009;461:798-801.
-
(2009)
Nature
, vol.461
, pp. 798-801
-
-
Thomas, D.L.1
Thio, C.L.2
Martin, M.P.3
Qi, Y.4
Ge, D.5
O'Huigin, C.6
-
7
-
-
84887993940
-
Interferon-stimulated genes and their role in controlling hepatitis C virus
-
Metz P, Reuter A, Bender S, Bartenschlager R. Interferon-stimulated genes and their role in controlling hepatitis C virus. J Hepatol 2013;59:1331-1341.
-
(2013)
J Hepatol
, vol.59
, pp. 1331-1341
-
-
Metz, P.1
Reuter, A.2
Bender, S.3
Bartenschlager, R.4
-
8
-
-
82955187705
-
Interferon-stimulated genes and their antiviral effector functions
-
Schoggins JW, Rice CM. Interferon-stimulated genes and their antiviral effector functions. Curr Opin Virol 2012;1:519-525.
-
(2012)
Curr Opin Virol
, vol.1
, pp. 519-525
-
-
Schoggins, J.W.1
Rice, C.M.2
-
9
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell 2010;140:805-820.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
10
-
-
33750976374
-
5'-Triphosphate RNA is the ligand for RIG-I
-
Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, Kato H, et al. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006;314:994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
Kato, H.6
-
11
-
-
70349728538
-
Activation of MDA5 requires higher-order RNA structures generated during virus infection
-
Pichlmair A, Schulz O, Tan CP, Rehwinkel J, Kato H, Takeuchi O, et al. Activation of MDA5 requires higher-order RNA structures generated during virus infection. J Virol 2009;83:10761-10769.
-
(2009)
J Virol
, vol.83
, pp. 10761-10769
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Rehwinkel, J.4
Kato, H.5
Takeuchi, O.6
-
12
-
-
67749133995
-
5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
-
Schmidt A, Schwerd T, Hamm W, Hellmuth JC, Cui S, Wenzel M, et al. 5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I. Proc Natl Acad Sci U S A 2009;106:12067-12072.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12067-12072
-
-
Schmidt, A.1
Schwerd, T.2
Hamm, W.3
Hellmuth, J.C.4
Cui, S.5
Wenzel, M.6
-
13
-
-
79956314622
-
Immune signaling by RIG-I-like receptors
-
Loo YM, Gale M Jr. Immune signaling by RIG-I-like receptors. Immunity 2011;34:680-692.
-
(2011)
Immunity
, vol.34
, pp. 680-692
-
-
Loo, Y.M.1
Gale, M.2
-
14
-
-
78651358320
-
Pattern recognition of viral nucleic acids by RIG-I-like helicases
-
Schmidt A, Endres S, Rothenfusser S. Pattern recognition of viral nucleic acids by RIG-I-like helicases. J Mol Med 2011;89:5-12.
-
(2011)
J Mol Med
, vol.89
, pp. 5-12
-
-
Schmidt, A.1
Endres, S.2
Rothenfusser, S.3
-
15
-
-
84880285547
-
Regulation of hepatic innate immunity by hepatitis C virus
-
Horner SM, Gale M Jr. Regulation of hepatic innate immunity by hepatitis C virus. Nat Med 2013;19:879-888.
-
(2013)
Nat Med
, vol.19
, pp. 879-888
-
-
Horner, S.M.1
Gale, M.2
-
16
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 2005;437:1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
Bartenschlager, R.6
-
17
-
-
79955542915
-
A diverse range of gene products are effectors of the type I interferon antiviral response
-
Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT, Bieniasz P, et al. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 2011;472:481-485.
-
(2011)
Nature
, vol.472
, pp. 481-485
-
-
Schoggins, J.W.1
Wilson, S.J.2
Panis, M.3
Murphy, M.Y.4
Jones, C.T.5
Bieniasz, P.6
-
18
-
-
13944253573
-
Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I
-
Sumpter R Jr, Loo YM, Foy E, Li K, Yoneyama M, Fujita T, et al. Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J Virol 2005;79:2689-2699.
-
(2005)
J Virol
, vol.79
, pp. 2689-2699
-
-
Sumpter, R.1
Loo, Y.M.2
Foy, E.3
Li, K.4
Yoneyama, M.5
Fujita, T.6
-
19
-
-
0033594380
-
Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Irish Hepatology Research Group
-
Kenny-Walsh E. Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Irish Hepatology Research Group. N Engl J Med 1999;340:1228-1233.
-
(1999)
N Engl J Med
, vol.340
, pp. 1228-1233
-
-
Kenny-Walsh, E.1
-
20
-
-
84874964101
-
Expression of heterologous proteins flanked by NS3-4A cleavage sites within the hepatitis C virus polyprotein
-
Horwitz JA, Dorner M, Friling T, Donovan BM, Vogt A, Loureiro J, et al. Expression of heterologous proteins flanked by NS3-4A cleavage sites within the hepatitis C virus polyprotein. Virology 2013;439:23-33.
-
(2013)
Virology
, vol.439
, pp. 23-33
-
-
Horwitz, J.A.1
Dorner, M.2
Friling, T.3
Donovan, B.M.4
Vogt, A.5
Loureiro, J.6
-
21
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
Lindenbach BD, Evans MJ, Syder AJ, Wolk B, Tellinghuisen TL, Liu CC, et al. Complete replication of hepatitis C virus in cell culture. Science 2005;309:623-626.
-
(2005)
Science
, vol.309
, pp. 623-626
-
-
Lindenbach, B.D.1
Evans, M.J.2
Syder, A.J.3
Wolk, B.4
Tellinghuisen, T.L.5
Liu, C.C.6
-
22
-
-
58049198421
-
IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells
-
Liu S, Wang H, Jin Y, Podolsky R, Reddy MV, Pedersen J, et al. IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells. Hum Mol Genet 2009;18:358-365.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 358-365
-
-
Liu, S.1
Wang, H.2
Jin, Y.3
Podolsky, R.4
Reddy, M.V.5
Pedersen, J.6
-
23
-
-
33745240931
-
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
-
Smyth DJ, Cooper JD, Bailey R, Field S, Burren O, Smink LJ, et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet 2006;38:617-619.
-
(2006)
Nat Genet
, vol.38
, pp. 617-619
-
-
Smyth, D.J.1
Cooper, J.D.2
Bailey, R.3
Field, S.4
Burren, O.5
Smink, L.J.6
-
24
-
-
65249131713
-
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
-
Nejentsev S, Walker N, Riches D, Egholm M, Todd JA. Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 2009;324:387-389.
-
(2009)
Science
, vol.324
, pp. 387-389
-
-
Nejentsev, S.1
Walker, N.2
Riches, D.3
Egholm, M.4
Todd, J.A.5
-
25
-
-
67649415364
-
Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes
-
Shigemoto T, Kageyama M, Hirai R, Zheng J, Yoneyama M, Fujita T. Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes. J Biol Chem 2009;284:13348-13354.
-
(2009)
J Biol Chem
, vol.284
, pp. 13348-13354
-
-
Shigemoto, T.1
Kageyama, M.2
Hirai, R.3
Zheng, J.4
Yoneyama, M.5
Fujita, T.6
-
26
-
-
29144462494
-
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
-
Li XD, Sun L, Seth RB, Pineda G, Chen ZJ. Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc Natl Acad Sci U S A 2005;102:17717-17722.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 17717-17722
-
-
Li, X.D.1
Sun, L.2
Seth, R.B.3
Pineda, G.4
Chen, Z.J.5
-
27
-
-
37849045856
-
Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1
-
Fredericksen BL, Keller BC, Fornek J, Katze MG, Gale M Jr. Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1. J Virol 2008;82:609-616.
-
(2008)
J Virol
, vol.82
, pp. 609-616
-
-
Fredericksen, B.L.1
Keller, B.C.2
Fornek, J.3
Katze, M.G.4
Gale, M.5
-
28
-
-
70349513508
-
A genome-wide genetic screen for host factors required for hepatitis C virus propagation
-
Li Q, Brass AL, Ng A, Hu Z, Xavier RJ, Liang TJ, et al. A genome-wide genetic screen for host factors required for hepatitis C virus propagation. Proc Natl Acad Sci U S A 2009;106:16410-16415.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16410-16415
-
-
Li, Q.1
Brass, A.L.2
Ng, A.3
Hu, Z.4
Xavier, R.J.5
Liang, T.J.6
-
29
-
-
84927711692
-
HepG2 cells mount an effective antiviral interferon-lambda based innate immune response to hepatitis C virus infection
-
Epub ahead of print
-
Israelow B, Narbus CM, Sourisseau M, Evans MJ. HepG2 cells mount an effective antiviral interferon-lambda based innate immune response to hepatitis C virus infection. Hepatology 2014 [Epub ahead of print].
-
(2014)
Hepatology
-
-
Israelow, B.1
Narbus, C.M.2
Sourisseau, M.3
Evans, M.J.4
-
30
-
-
82455175215
-
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
-
Andrus L, Marukian S, Jones CT, Catanese MT, Sheahan TP, Schoggins JW, et al. Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells. Hepatology 2011;54:1901-1912.
-
(2011)
Hepatology
, vol.54
, pp. 1901-1912
-
-
Andrus, L.1
Marukian, S.2
Jones, C.T.3
Catanese, M.T.4
Sheahan, T.P.5
Schoggins, J.W.6
-
31
-
-
84873523444
-
Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling
-
Motz C, Schuhmann KM, Kirchhofer A, Moldt M, Witte G, Conzelmann KK, et al. Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling. Science 2013;339:690-693.
-
(2013)
Science
, vol.339
, pp. 690-693
-
-
Motz, C.1
Schuhmann, K.M.2
Kirchhofer, A.3
Moldt, M.4
Witte, G.5
Conzelmann, K.K.6
-
32
-
-
33744791510
-
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
-
Gitlin L, Barchet W, Gilfillan S, Cella M, Beutler B, Flavell RA, et al. Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci U S A 2006;103:8459-8464.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 8459-8464
-
-
Gitlin, L.1
Barchet, W.2
Gilfillan, S.3
Cella, M.4
Beutler, B.5
Flavell, R.A.6
-
33
-
-
46949097299
-
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
-
Kato H, Takeuchi O, Mikamo-Satoh E, Hirai R, Kawai T, Matsushita K, et al. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J Exp Med 2008;205:1601-1610.
-
(2008)
J Exp Med
, vol.205
, pp. 1601-1610
-
-
Kato, H.1
Takeuchi, O.2
Mikamo-Satoh, E.3
Hirai, R.4
Kawai, T.5
Matsushita, K.6
-
34
-
-
84883491208
-
Visualisation of direct interaction of MDA5 and the dsRNA replicative intermediate form of positive strand RNA viruses
-
Triantafilou K, Vakakis E, Kar S, Richer E, Evans GL, Triantafilou M. Visualisation of direct interaction of MDA5 and the dsRNA replicative intermediate form of positive strand RNA viruses. J Cell Sci 2012;125:4761-4769.
-
(2012)
J Cell Sci
, vol.125
, pp. 4761-4769
-
-
Triantafilou, K.1
Vakakis, E.2
Kar, S.3
Richer, E.4
Evans, G.L.5
Triantafilou, M.6
-
35
-
-
77955367899
-
Study of transcriptional effects in Cis at the IFIH1 locus
-
Zouk H, Marchand L, Polychronakos C. Study of transcriptional effects in Cis at the IFIH1 locus. PLoS One 2010;5:e11564.
-
(2010)
PLoS One
, vol.5
, pp. e11564
-
-
Zouk, H.1
Marchand, L.2
Polychronakos, C.3
-
36
-
-
80054703126
-
Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA
-
Kowalinski E, Lunardi T, McCarthy AA, Louber J, Brunel J, Grigorov B, et al. Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell 2011;147:423-435.
-
(2011)
Cell
, vol.147
, pp. 423-435
-
-
Kowalinski, E.1
Lunardi, T.2
McCarthy, A.A.3
Louber, J.4
Brunel, J.5
Grigorov, B.6
-
37
-
-
80054685883
-
Structural insights into RNA recognition by RIG-I
-
Luo D, Ding SC, Vela A, Kohlway A, Lindenbach BD, Pyle AM. Structural insights into RNA recognition by RIG-I. Cell 2011;147:409-422.
-
(2011)
Cell
, vol.147
, pp. 409-422
-
-
Luo, D.1
Ding, S.C.2
Vela, A.3
Kohlway, A.4
Lindenbach, B.D.5
Pyle, A.M.6
-
38
-
-
81555204380
-
Structural basis of RNA recognition and activation by innate immune receptor RIG-I
-
Jiang F, Ramanathan A, Miller MT, Tang GQ, Gale M Jr, Patel SS, et al. Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature 2011;479:423-427.
-
(2011)
Nature
, vol.479
, pp. 423-427
-
-
Jiang, F.1
Ramanathan, A.2
Miller, M.T.3
Tang, G.Q.4
Gale, M.5
Patel, S.S.6
-
39
-
-
84872604349
-
Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5
-
Wu B, Peisley A, Richards C, Yao H, Zeng X, Lin C, et al. Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5. Cell 2013;152:276-289.
-
(2013)
Cell
, vol.152
, pp. 276-289
-
-
Wu, B.1
Peisley, A.2
Richards, C.3
Yao, H.4
Zeng, X.5
Lin, C.6
-
40
-
-
84862909216
-
Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition
-
Peisley A, Lin C, Wu B, Orme-Johnson M, Liu M, Walz T, et al. Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Proc Natl Acad Sci U S A 2011;108:21010-21015.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 21010-21015
-
-
Peisley, A.1
Lin, C.2
Wu, B.3
Orme-Johnson, M.4
Liu, M.5
Walz, T.6
-
43
-
-
84899495767
-
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
-
Rice GI, Del Toro Duany Y, Jenkinson EM, Forte GM, Anderson BH, Ariaudo G, et al. Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling. Nat Genet 2014;46:503-509.
-
(2014)
Nat Genet
, vol.46
, pp. 503-509
-
-
Rice, G.I.1
Del Toro Duany, Y.2
Jenkinson, E.M.3
Forte, G.M.4
Anderson, B.H.5
Ariaudo, G.6
-
44
-
-
84885443409
-
Association of IFIH1 rs1990760 polymorphism with susceptibility to autoimmune diseases: a meta-analysis
-
Cen H, Wang W, Leng RX, Wang TY, Pan HF, Fan YG, et al. Association of IFIH1 rs1990760 polymorphism with susceptibility to autoimmune diseases: a meta-analysis. Autoimmunity 2013;46:455-462.
-
(2013)
Autoimmunity
, vol.46
, pp. 455-462
-
-
Cen, H.1
Wang, W.2
Leng, R.X.3
Wang, T.Y.4
Pan, H.F.5
Fan, Y.G.6
|