Liver enzymes, metabolomics and genome-wide association studies: From systems biology to the personalized medicine

World Journal of Gastroenterology

Volumn 21, Issue 3, 2015, Pages 711-725

  Sookoian, Silvia ^a   Pirola, Carlos J ^a  

^a INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

Author keywords

Alanineaminotransferase; Aminotransferases; Aspartate aminotransferase; Gene variants; Genetics; Glutamate oxalacetate transaminase; Glutamate pyruvate tran saminase; Glutamic acid; Metabolic syndrome; Metabolism; Metabolomics; Nonalcoholic fatty liver; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; PNPLA3; Single nucleotide polymorphisms; Systems biology; Transaminases

Indexed keywords

1 AMINOCYCLOPROPANE 1 CARBOXYLATE SYNTHASE LIKE PROTEIN 1; 1 AMINOCYCLOPROPANE 1 CARBOXYLATE SYNTHASE LIKE PROTEIN 2; ALANINE AMINOTRANSFERASE; ALANINE AMINOTRANSFERASE 1; ALANINE AMINOTRANSFERASE 2; ASPARTATE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE CYTOPLASMIC 2 ISOENZYME; ASPARTATE AMINOTRANSFERASE ISOENZYME 1; ASPARTATE AMINOTRANSFERASE ISOENZYME 2; FATTY ACID BINDING PROTEIN; GLUCOSE; KYNURENINE ALPHA AMINOADIPATE AMINOTRANSFERASE MITOCHONDRIAL ISOENZYME; KYNURENINE AMINOTRANSFERASE; KYNURENINE OXOGLUTARATE TRANSAMINASE 1; KYNURENINE OXOGLUTARATE TRANSAMINASE 3; LIVER ENZYME; TYROSINE AMINOTRANSFERASE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; GENE FUNCTION; GENETIC ASSOCIATION; GLUCOSE METABOLISM; HUMAN; INTRON; ISCHEMIC HEART DISEASE; LIVER CELL DAMAGE; LIVER FUNCTION; LIVER INJURY; METABOLIC DISORDER; METABOLIC SYNDROME X; METABOLOMICS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOPHYSIOLOGY; PERSONALIZED MEDICINE; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMS BIOLOGY; TRANSAMINATION; ANIMAL; BLOOD; ENZYME ASSAY; ENZYMOLOGY; GENE REGULATORY NETWORK; GENETIC PREDISPOSITION; GENETICS; GENOMICS; HEREDITY; LIVER; LIVER DISEASES; PHENOTYPE; PREDICTIVE VALUE; PROCEDURES; PROGNOSIS; PROTEIN PROTEIN INTERACTION; RISK FACTOR;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BIOMARKERS; CLINICAL ENZYME TESTS; GENE REGULATORY NETWORKS; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HEREDITY; HUMANS; LIVER; LIVER DISEASES; METABOLOMICS; PHENOTYPE; PRECISION MEDICINE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROTEIN INTERACTION MAPS; RISK FACTORS; SYSTEMS BIOLOGY;

EID: 84921485234     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v21.i3.711     Document Type: Review

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