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Volumn 64, Issue 5, 2015, Pages 800-812

Circulating microRNA signature in non-alcoholic fatty liver disease: From serum non-coding RNAs to liver histology and disease pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ARGONAUTE 2 PROTEIN; MICRORNA; MICRORNA 122; MICRORNA 125B; MICRORNA 192; MICRORNA 19A; MICRORNA 19B; MICRORNA 375; SMALL UNTRANSLATED RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA; AMINOTRANSFERASE; ARGONAUTE PROTEIN; BIOLOGICAL MARKER; EIF2C2 PROTEIN, HUMAN; MIRN122 MICRORNA, HUMAN;

EID: 84928885523     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2014-306996     Document Type: Article
Times cited : (449)

References (42)
  • 1
    • 49949117302 scopus 로고    scopus 로고
    • Widespread changes in protein synthesis induced by microRNAs
    • Selbach M, Schwanhausser B, Thierfelder N, et al. Widespread changes in protein synthesis induced by microRNAs. Nature 2008;455:58-63.
    • (2008) Nature , vol.455 , pp. 58-63
    • Selbach, M.1    Schwanhausser, B.2    Thierfelder, N.3
  • 2
    • 84863425849 scopus 로고    scopus 로고
    • Small RNAs have a large impact: Circulating microRNAs as biomarkers for human diseases
    • Weiland M, Gao XH, Zhou L, et al. Small RNAs have a large impact: circulating microRNAs as biomarkers for human diseases. RNA Biol 2012;9:850-9.
    • (2012) RNA Biol , vol.9 , pp. 850-859
    • Weiland, M.1    Gao, X.H.2    Zhou, L.3
  • 3
    • 84856695673 scopus 로고    scopus 로고
    • Circulating microRNAs: Novel biomarkers and extracellular communicators in cardiovascular disease?
    • Creemers EE, Tijsen AJ, Pinto YM. Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease? Circ Res 2012;110:483-95.
    • (2012) Circ Res , vol.110 , pp. 483-495
    • Creemers, E.E.1    Tijsen, A.J.2    Pinto, Y.M.3
  • 4
    • 84867334962 scopus 로고    scopus 로고
    • Cell-to-cell miRNA transfer: From body homeostasis to therapy
    • Redis RS, Calin S, Yang Y, et al. Cell-to-cell miRNA transfer: from body homeostasis to therapy. Pharmacol Ther 2012;136:169-74.
    • (2012) Pharmacol Ther , vol.136 , pp. 169-174
    • Redis, R.S.1    Calin, S.2    Yang, Y.3
  • 5
    • 84879092232 scopus 로고    scopus 로고
    • Circulating MicroRNA-122 signature in nonalcoholic fatty liver disease and cardiovascular disease: A new endocrine system in metabolic syndrome
    • Pirola CJ, Gianotti TF, Castano GO, et al. Circulating MicroRNA-122 signature in nonalcoholic fatty liver disease and cardiovascular disease: a new endocrine system in metabolic syndrome. Hepatology 2013;57:2545-7.
    • (2013) Hepatology , vol.57 , pp. 2545-2547
    • Pirola, C.J.1    Gianotti, T.F.2    Castano, G.O.3
  • 6
    • 79952231349 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: Distinct clinicopathologic meanings
    • Brunt EM, Kleiner DE, Wilson LA, et al. Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings. Hepatology 2011;53:810-20.
    • (2011) Hepatology , vol.53 , pp. 810-820
    • Brunt, E.M.1    Kleiner, D.E.2    Wilson, L.A.3
  • 7
    • 78649568544 scopus 로고    scopus 로고
    • Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: Impact of liver methylation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha promoter
    • Sookoian S, Rosselli MS, Gemma C, et al. Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: impact of liver methylation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha promoter. Hepatology 2010;52:1992-2000.
    • (2010) Hepatology , vol.52 , pp. 1992-2000
    • Sookoian, S.1    Rosselli, M.S.2    Gemma, C.3
  • 8
    • 84881546730 scopus 로고    scopus 로고
    • Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease
    • Pirola CJ, Gianotti TF, Burgueno AL, et al. Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease. Gut 2013;62:1356-63.
    • (2013) Gut , vol.62 , pp. 1356-1363
    • Pirola, C.J.1    Gianotti, T.F.2    Burgueno, A.L.3
  • 9
    • 84881232944 scopus 로고    scopus 로고
    • Cardiovascular and systemic risk in nonalcoholic fatty liver disease-atherosclerosis as a major player in the natural course of NAFLD
    • Lonardo A, Sookoian S, Chonchol M, et al. Cardiovascular and systemic risk in nonalcoholic fatty liver disease-atherosclerosis as a major player in the natural course of NAFLD. Curr Pharm Des 2013;19:5177-92.
    • (2013) Curr Pharm des , vol.19 , pp. 5177-5192
    • Lonardo, A.1    Sookoian, S.2    Chonchol, M.3
  • 10
    • 3242736704 scopus 로고    scopus 로고
    • Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
    • Meister G, Landthaler M, Patkaniowska A, et al. Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell 2004;15:185-97.
    • (2004) Mol Cell , vol.15 , pp. 185-197
    • Meister, G.1    Landthaler, M.2    Patkaniowska, A.3
  • 11
    • 79953202200 scopus 로고    scopus 로고
    • Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
    • Arroyo JD, Chevillet JR, Kroh EM, et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A 2011;108:5003-8.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 5003-5008
    • Arroyo, J.D.1    Chevillet, J.R.2    Kroh, E.M.3
  • 12
    • 23844523406 scopus 로고    scopus 로고
    • MiR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1
    • Chang J, Nicolas E, Marks D, et al. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol 2004;1:106-13.
    • (2004) RNA Biol , vol.1 , pp. 106-113
    • Chang, J.1    Nicolas, E.2    Marks, D.3
  • 13
    • 33947712377 scopus 로고    scopus 로고
    • Identification of a novel polymorphism in the 30UTR of the L-arginine transporter gene SLC7A1: Contribution to hypertension and endothelial dysfunction
    • Yang Z, Venardos K, Jones E, et al. Identification of a novel polymorphism in the 30UTR of the L-arginine transporter gene SLC7A1: contribution to hypertension and endothelial dysfunction. Circulation 2007;115:1269-74.
    • (2007) Circulation , vol.115 , pp. 1269-1274
    • Yang, Z.1    Venardos, K.2    Jones, E.3
  • 14
    • 61649092260 scopus 로고    scopus 로고
    • Mechanistic insights into the link between a polymorphism of the 30UTR of the SLC7A1 gene and hypertension
    • Yang Z, Kaye DM. Mechanistic insights into the link between a polymorphism of the 30UTR of the SLC7A1 gene and hypertension. Hum Mutat 2009;30:328-33.
    • (2009) Hum Mutat , vol.30 , pp. 328-333
    • Yang, Z.1    Kaye, D.M.2
  • 16
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007;318:1931-4.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 18
    • 80053219898 scopus 로고    scopus 로고
    • Liver transcriptional profile of atherosclerosis-related genes in human nonalcoholic fatty liver disease
    • Sookoian S, Gianotti TF, Rosselli MS, et al. Liver transcriptional profile of atherosclerosis-related genes in human nonalcoholic fatty liver disease. Atherosclerosis 2011;218:378-85.
    • (2011) Atherosclerosis , vol.218 , pp. 378-385
    • Sookoian, S.1    Gianotti, T.F.2    Rosselli, M.S.3
  • 19
    • 84890547086 scopus 로고    scopus 로고
    • Limited value of plasma cytokeratin-18 as a biomarker for NASH and fibrosis in patients with non-alcoholic fatty liver disease
    • Cusi K, Chang Z, Harrison S, et al. Limited value of plasma cytokeratin-18 as a biomarker for NASH and fibrosis in patients with non-alcoholic fatty liver disease. J Hepatol 2014;60:167-74.
    • (2014) J Hepatol , vol.60 , pp. 167-174
    • Cusi, K.1    Chang, Z.2    Harrison, S.3
  • 20
    • 58149386462 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression
    • Cheung O, Puri P, Eicken C, et al. Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression. Hepatology 2008;48:1810-20.
    • (2008) Hepatology , vol.48 , pp. 1810-1820
    • Cheung, O.1    Puri, P.2    Eicken, C.3
  • 21
    • 84885031036 scopus 로고    scopus 로고
    • Kinetics of miR-122 expression in the liver during acute HCV infection
    • Choi Y, Dienes HP, Krawczynski K. Kinetics of miR-122 expression in the liver during acute HCV infection. PLoS ONE 2013;8:e76501.
    • (2013) PLoS ONE , vol.8 , pp. e76501
    • Choi, Y.1    Dienes, H.P.2    Krawczynski, K.3
  • 22
    • 70349976819 scopus 로고    scopus 로고
    • Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
    • Coulouarn C, Factor VM, Andersen JB, et al. Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene 2009;28:3526-36.
    • (2009) Oncogene , vol.28 , pp. 3526-3536
    • Coulouarn, C.1    Factor, V.M.2    Andersen, J.B.3
  • 23
    • 63149121152 scopus 로고    scopus 로고
    • Circulating microRNAs, potential biomarkers for drug-induced liver injury
    • Wang K, Zhang S, Marzolf B, et al. Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc Natl Acad Sci U S A 2009;106:4402-7.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4402-4407
    • Wang, K.1    Zhang, S.2    Marzolf, B.3
  • 24
    • 77956269092 scopus 로고    scopus 로고
    • Hepatocellular ballooning in NASH
    • Caldwell S, Ikura Y, Dias D, et al. Hepatocellular ballooning in NASH. J Hepatol 2010;53:719-23.
    • (2010) J Hepatol , vol.53 , pp. 719-723
    • Caldwell, S.1    Ikura, Y.2    Dias, D.3
  • 25
    • 84874109529 scopus 로고    scopus 로고
    • MiR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression
    • Li J, Ghazwani M, Zhang Y, et al. miR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression. J Hepatol 2013;58:522-8.
    • (2013) J Hepatol , vol.58 , pp. 522-528
    • Li, J.1    Ghazwani, M.2    Zhang, Y.3
  • 26
    • 84868211262 scopus 로고    scopus 로고
    • Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced and inflammatory liver diseases
    • Bala S, Petrasek J, Mundkur S, et al. Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced and inflammatory liver diseases. Hepatology 2012;56:1946-57.
    • (2012) Hepatology , vol.56 , pp. 1946-1957
    • Bala, S.1    Petrasek, J.2    Mundkur, S.3
  • 27
    • 78649837734 scopus 로고    scopus 로고
    • Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases
    • Zhang Y, Jia Y, Zheng R, et al. Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases. Clin Chem 2010;56:1830-8.
    • (2010) Clin Chem , vol.56 , pp. 1830-1838
    • Zhang, Y.1    Jia, Y.2    Zheng, R.3
  • 28
    • 58049217312 scopus 로고    scopus 로고
    • MicroRNA-122 stimulates translation of hepatitis C virus RNA
    • Henke JI, Goergen D, Zheng J, et al. microRNA-122 stimulates translation of hepatitis C virus RNA. EMBO J 2008;27:3300-10.
    • (2008) EMBO J , vol.27 , pp. 3300-3310
    • Henke, J.I.1    Goergen, D.2    Zheng, J.3
  • 29
    • 77952346716 scopus 로고    scopus 로고
    • MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism
    • Lu H, Buchan RJ, Cook SA. MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism. Cardiovasc Res 2010;86:410-20.
    • (2010) Cardiovasc Res , vol.86 , pp. 410-420
    • Lu, H.1    Buchan, R.J.2    Cook, S.A.3
  • 30
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • Birney E, Stamatoyannopoulos JA, Dutta A, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007;447:799-816.
    • (2007) Nature , vol.447 , pp. 799-816
    • Birney, E.1    Stamatoyannopoulos, J.A.2    Dutta, A.3
  • 31
    • 84874646362 scopus 로고    scopus 로고
    • A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets
    • Khorshid M, Hausser J, Zavolan M, et al. A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets. Nat Methods 2013;10:253-5.
    • (2013) Nat Methods , vol.10 , pp. 253-255
    • Khorshid, M.1    Hausser, J.2    Zavolan, M.3
  • 32
    • 33847682663 scopus 로고    scopus 로고
    • MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
    • Kato M, Zhang J, Wang M, et al. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A 2007;104:3432-7.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3432-3437
    • Kato, M.1    Zhang, J.2    Wang, M.3
  • 33
    • 65249093130 scopus 로고    scopus 로고
    • MiR-375 maintains normal pancreatic alpha- and beta-cell mass
    • Poy MN, Hausser J, Trajkovski M, et al. miR-375 maintains normal pancreatic alpha- and beta-cell mass. Proc Natl Acad Sci U S A 2009;106:5813-18.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5813-5818
    • Poy, M.N.1    Hausser, J.2    Trajkovski, M.3
  • 34
    • 77955611511 scopus 로고    scopus 로고
    • MiR-192 mediates TGF-beta/Smad3-driven renal fibrosis
    • Chung AC, Huang XR, Meng X, et al. miR-192 mediates TGF-beta/Smad3-driven renal fibrosis. J Am Soc Nephrol 2010;21:1317-25.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1317-1325
    • Chung, A.C.1    Huang, X.R.2    Meng, X.3
  • 35
    • 84867898027 scopus 로고    scopus 로고
    • A miR-19 regulon that controls NF-kappaB signaling
    • Gantier MP, Stunden HJ, McCoy CE, et al. A miR-19 regulon that controls NF-kappaB signaling. Nucleic Acids Res 2012;40:8048-58.
    • (2012) Nucleic Acids Res , vol.40 , pp. 8048-8058
    • Gantier, M.P.1    Stunden, H.J.2    McCoy, C.E.3
  • 36
    • 78049294740 scopus 로고    scopus 로고
    • Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1
    • Villeneuve LM, Kato M, Reddy MA, et al. Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes 2010;59:2904-15.
    • (2010) Diabetes , vol.59 , pp. 2904-2915
    • Villeneuve, L.M.1    Kato, M.2    Reddy, M.A.3
  • 37
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman RC, Farh KK, Burge CB, et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009;19:92-105.
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3
  • 38
    • 84856694355 scopus 로고    scopus 로고
    • MicroRNAs in vascular and metabolic disease
    • Zampetaki A, Mayr M. MicroRNAs in vascular and metabolic disease. Circ Res 2012;110:508-22.
    • (2012) Circ Res , vol.110 , pp. 508-522
    • Zampetaki, A.1    Mayr, M.2
  • 39
    • 40249106014 scopus 로고    scopus 로고
    • Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver
    • Elmen J, Lindow M, Silahtaroglu A, et al. Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res 2008;36:1153-62.
    • (2008) Nucleic Acids Res , vol.36 , pp. 1153-1162
    • Elmen, J.1    Lindow, M.2    Silahtaroglu, A.3
  • 40
    • 84864773072 scopus 로고    scopus 로고
    • MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
    • Tsai WC, Hsu SD, Hsu CS, et al. MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. J Clin Invest 2012;122:2884-97.
    • (2012) J Clin Invest , vol.122 , pp. 2884-2897
    • Tsai, W.C.1    Hsu, S.D.2    Hsu, C.S.3
  • 41
    • 84891375969 scopus 로고    scopus 로고
    • MicroRNA-122 down-regulation may play a role in severe myocardial fibrosis in human aortic stenosis through TGF-beta1 up-regulation
    • Lond
    • Beaumont J, Lopez B, Hermida N, et al. microRNA-122 down-regulation may play a role in severe myocardial fibrosis in human aortic stenosis through TGF-beta1 up-regulation. Clin Sci (Lond) 2014;126:497-506.
    • (2014) Clin Sci , vol.126 , pp. 497-506
    • Beaumont, J.1    Lopez, B.2    Hermida, N.3
  • 42
    • 84860469242 scopus 로고    scopus 로고
    • Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease
    • Min HK, Kapoor A, Fuchs M, et al. Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease. Cell Metab 2012;15:665-74.
    • (2012) Cell Metab , vol.15 , pp. 665-674
    • Min, H.K.1    Kapoor, A.2    Fuchs, M.3


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