Apoptosis-associated speck-like protein containing a CARD forms specks but does not activate caspase-1 in the absence of NLRP3 during macrophage swelling

Journal of Immunology

Volumn 194, Issue 3, 2015, Pages 1261-1273

  Compan, Vincent ^a,c   Martín Sánchez, Fátima ^b   Baroja Mazo, Alberto ^b   Lopez Castejon, Gloria ^a   Gomez, Ana I ^b   Verkhratsky, Alexei ^a   Brough, David ^a   Pelegrín, Pablo ^a,b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

^c INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING A C TERMINAL CASPASE RECRUITMENT DOMAIN; APOPTOSIS REGULATORY PROTEIN; CALCIUM ION; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTATE DEHYDROGENASE; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 2; CALCIUM CHANNEL; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE; TRPV2 PROTEIN, MOUSE; VANILLOID RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL PERMEABILIZATION; CELL SWELLING; CELL VIABILITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME RELEASE; IMMUNOREACTIVITY; INTRACELLULAR SIGNALING; MACROPHAGE; MALE; MOUSE; NONHUMAN; OLIGOMERIZATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PYROPTOSIS; ANIMAL; CELL LINE; CHEMISTRY; HUMAN; KNOCKOUT MOUSE; METABOLISM; PROTEIN DOMAIN; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM CHANNELS; CARRIER PROTEINS; CASPASE 1; CELL LINE; ENZYME ACTIVATION; HUMANS; INFLAMMASOMES; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; TRPV CATION CHANNELS;

EID: 84921456203     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1301676     Document Type: Article

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