-
1
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth C, McLellan MD, Vandin F, et al. 2013. Mutational landscape and significance across 12 major cancer types. Nature 502:333-39
-
(2013)
Nature
, vol.502
, pp. 333-339
-
-
Kandoth, C.1
McLellan, M.D.2
Vandin, F.3
-
2
-
-
84899740340
-
DNA sequencing of cancer: What have we learned?
-
Chmielecki J, Meyerson M. 2014. DNA sequencing of cancer: What have we learned?. Annu. Rev. Med. 65:63-79
-
(2014)
Annu. Rev. Med.
, vol.65
, pp. 63-79
-
-
Chmielecki, J.1
Meyerson, M.2
-
3
-
-
84880896589
-
Use of pharmacogenetics for predicting cancer prognosis and treatment exposure, response and toxicity
-
Hertz DL, McLeod HL. 2013. Use of pharmacogenetics for predicting cancer prognosis and treatment exposure, response and toxicity. J. Hum. Genet. 58:346-52
-
(2013)
J. Hum. Genet.
, vol.58
, pp. 346-352
-
-
Hertz, D.L.1
McLeod, H.L.2
-
4
-
-
0035033019
-
Pharmacogenomics: Unlocking the human genome for better drug therapy
-
McLeod HL, EvansWE.2001. Pharmacogenomics: unlocking the human genome for better drug therapy. Annu. Rev. Pharmacol. Toxicol. 41:101-21
-
(2001)
Annu. Rev. Pharmacol. Toxicol.
, vol.41
, pp. 101-121
-
-
McLeod, H.L.1
Evans, W.E.2
-
5
-
-
84855906545
-
Using genome-wide association studies to identify genes important in serious adverse drug reactions
-
Daly AK. 2012. Using genome-wide association studies to identify genes important in serious adverse drug reactions. Annu. Rev. Pharmacol. Toxicol. 52:21-35
-
(2012)
Annu. Rev. Pharmacol. Toxicol.
, vol.52
, pp. 21-35
-
-
Daly, A.K.1
-
6
-
-
84883192385
-
Abacavir pharmacogenetics-from initial reports to standard of care
-
Martin MA, Kroetz DL. 2013. Abacavir pharmacogenetics-from initial reports to standard of care. Pharmacotherapy 33:765-75
-
(2013)
Pharmacotherapy
, vol.33
, pp. 765-775
-
-
Martin, M.A.1
Kroetz, D.L.2
-
7
-
-
84901036161
-
Using pharmacogene polymorphism panels to detect germline pharmacodynamic markers in oncology
-
Hertz DL, McLeod HL. 2014. Using pharmacogene polymorphism panels to detect germline pharmacodynamic markers in oncology. Clin. Cancer Res. 20:2530-40
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 2530-2540
-
-
Hertz, D.L.1
McLeod, H.L.2
-
8
-
-
84866593873
-
Pharmacogenomics and individualized medicine: Translating science into practice
-
Crews KR, Hicks JK, Pui CH, et al. 2012. Pharmacogenomics and individualized medicine: translating science into practice. Clin. Pharmacol. Ther. 92:467-75
-
(2012)
Clin. Pharmacol. Ther.
, vol.92
, pp. 467-475
-
-
Crews, K.R.1
Hicks, J.K.2
Pui, C.H.3
-
9
-
-
59849108152
-
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: Methods of the EGAPP working group
-
Teutsch SM, Bradley LA, Palomaki GE, et al. 2009. The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP working group. Genet. Med. 11:3-14
-
(2009)
Genet. Med.
, vol.11
, pp. 3-14
-
-
Teutsch, S.M.1
Bradley, L.A.2
Palomaki, G.E.3
-
10
-
-
0026680687
-
Closing in on a breast cancer gene on chromosome 17q
-
Hall JM, Friedman L, Guenther C, et al. 1992. Closing in on a breast cancer gene on chromosome 17q. Am. J. Hum. Genet. 50:1235-42
-
(1992)
Am. J. Hum. Genet.
, vol.50
, pp. 1235-1242
-
-
Hall, J.M.1
Friedman, L.2
Guenther, C.3
-
11
-
-
0030811585
-
Double indemnity p53, BRCA and cancer
-
Brugarolas J, Jacks T. 1997. Double indemnity: p53, BRCA and cancer. Nat. Med. 3:721-22
-
(1997)
Nat. Med.
, vol.3
, pp. 721-722
-
-
Brugarolas, J.1
Jacks, T.2
-
12
-
-
0029821230
-
Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex
-
Poklar N, Pilch DS, Lippard SJ, et al. 1996. Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proc. Natl. Acad. Sci. USA 93:7606-11
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7606-7611
-
-
Poklar, N.1
Pilch, D.S.2
Lippard, S.J.3
-
13
-
-
0037403380
-
Improved survival in women with BRCA-Associated ovarian carcinoma
-
Cass I, Baldwin RL, Varkey T, et al. 2003. Improved survival in women with BRCA-Associated ovarian carcinoma. Cancer 97:2187-95
-
(2003)
Cancer
, vol.97
, pp. 2187-2195
-
-
Cass, I.1
Baldwin, R.L.2
Varkey, T.3
-
14
-
-
84864026311
-
BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: A report from the Australian ovarian cancer study group
-
AlsopK, Fereday S, MeldrumC, et al. 2012. BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian ovarian cancer study group. J. Clin. Oncol. 30:2654-63
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2654-2663
-
-
Alsop, K.1
Fereday, S.2
Meldrum, C.3
-
15
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, et al. 2005. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434:917-21
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
-
16
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant HE, Schultz N, Thomas HD, et al. 2005. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 434:913-17
-
(2005)
Nature
, vol.434
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
-
17
-
-
77955039099
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial
-
AudehMW, Carmichael J, Penson RT, et al. 2010. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 376:245-51
-
(2010)
Lancet
, vol.376
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
-
18
-
-
84863010984
-
Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer
-
Kaye SB, Lubinski J, Matulonis U, et al. 2012. Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer. J. Clin. Oncol. 30:372-79
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 372-379
-
-
Kaye, S.B.1
Lubinski, J.2
Matulonis, U.3
-
19
-
-
77955886707
-
Somaticmutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer
-
Hennessy BT, Timms KM, Carey MS, et al. 2010. Somaticmutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer. J. Clin. Oncol. 28:3570-6
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3570-3576
-
-
Hennessy, B.T.1
Timms, K.M.2
Carey, M.S.3
-
20
-
-
85047656642
-
Positive results for drug combo in I-SPY 2 trial
-
OF2
-
A2014. Positive results for drug combo in I-SPY 2 trial. Cancer Discov. 4:OF2
-
(2014)
Cancer Discov.
, vol.4
-
-
-
21
-
-
84865516911
-
HLA and pharmacogenetics of drug hypersensitivity
-
Pavlos R, Mallal S, Phillips E. 2012. HLA and pharmacogenetics of drug hypersensitivity. Pharmacogenomics 13:1285-306
-
(2012)
Pharmacogenomics
, vol.13
, pp. 1285-1306
-
-
Pavlos, R.1
Mallal, S.2
Phillips, E.3
-
22
-
-
79952173247
-
HLA-DQA102:01 is a major risk factor for lapatinibinduced hepatotoxicity in women with advanced breast cancer
-
Spraggs CF, Budde LR, Briley LP, et al. 2011. HLA-DQA102:01 is a major risk factor for lapatinibinduced hepatotoxicity in women with advanced breast cancer. J. Clin. Oncol. 29:667-73
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 667-673
-
-
Spraggs, C.F.1
Budde, L.R.2
Briley, L.P.3
-
23
-
-
84905860711
-
Prospective validation of HLA-DRB107:01 allele carriage as a predictive risk factor for lapatinib-induced liver injury
-
Schaid DJ, Spraggs CF, McDonnell SK, et al. 2014. Prospective validation of HLA-DRB107:01 allele carriage as a predictive risk factor for lapatinib-induced liver injury. J. Clin. Oncol. 32:2296-303
-
(2014)
J. Clin. Oncol.
, vol.32
, pp. 2296-2303
-
-
Schaid, D.J.1
Spraggs, C.F.2
McDonnell, S.K.3
-
24
-
-
0028861745
-
A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase
-
Krynetski EY, Schuetz JD, Galpin AJ, et al. 1995. A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. Proc. Natl. Acad. Sci. USA 92:949-53
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 949-953
-
-
Krynetski, E.Y.1
Schuetz, J.D.2
Galpin, A.J.3
-
25
-
-
0030986251
-
Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT3A, TPMT2): Mechanisms for the genetic polymorphism of TPMT activity
-
Tai HL, Krynetski EY, Schuetz EG, et al. 1997. Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT3A, TPMT2): mechanisms for the genetic polymorphism of TPMT activity. Proc. Natl. Acad. Sci. USA 94:6444-49
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6444-6449
-
-
Tai, H.L.1
Krynetski, E.Y.2
Schuetz, E.G.3
-
26
-
-
0032030953
-
Human thiopurine methyltransferase pharmacogenetics Kindred with a terminal exon splice junction mutation that results in loss of activity
-
Otterness DM, Szumlanski CL, Wood TC, Weinshilboum RM. 1998. Human thiopurine methyltransferase pharmacogenetics. Kindred with a terminal exon splice junction mutation that results in loss of activity. J. Clin. Investig. 101:1036-44
-
(1998)
J. Clin. Investig.
, vol.101
, pp. 1036-1044
-
-
Otterness, D.M.1
Szumlanski, C.L.2
Wood, T.C.3
Weinshilboum, R.M.4
-
27
-
-
0033486029
-
Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus
-
RellingMV, HancockML, RiveraGK, et al. 1999. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J. Natl. Cancer Inst. 91:2001-8
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 2001-2008
-
-
Relling, M.V.1
Hancock, M.L.2
Rivera, G.K.3
-
28
-
-
0025331198
-
Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
-
Lennard L, Lilleyman JS, Van Loon J, Weinshilboum RM. 1990. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia. Lancet 336:225-29
-
(1990)
Lancet
, vol.336
, pp. 225-229
-
-
Lennard, L.1
Lilleyman, J.S.2
Van Loon, J.3
Weinshilboum, R.M.4
-
29
-
-
0032212759
-
Thiopurine methyltransferase genotype predicts therapylimiting severe toxicity from azathioprine
-
Black AJ, McLeod HL, Capell HA, et al. 1998. Thiopurine methyltransferase genotype predicts therapylimiting severe toxicity from azathioprine. Ann. Intern. Med. 129:716-18
-
(1998)
Ann. Intern. Med.
, vol.129
, pp. 716-718
-
-
Black, A.J.1
McLeod, H.L.2
Capell, H.A.3
-
30
-
-
20144365645
-
Thiopurinemethyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia
-
Stanulla M, Schaeffeler E, Flohr T, et al. 2005. Thiopurinemethyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia. JAMA 293:1485-89
-
(2005)
JAMA
, vol.293
, pp. 1485-1489
-
-
Stanulla, M.1
Schaeffeler, E.2
Flohr, T.3
-
31
-
-
76749115697
-
Long-Term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia
-
Schmiegelow K, Forestier E, Hellebostad M, et al. 2010. Long-Term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia. Leukemia 24:345-54
-
(2010)
Leukemia
, vol.24
, pp. 345-354
-
-
Schmiegelow, K.1
Forestier, E.2
Hellebostad, M.3
-
32
-
-
84895756369
-
Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: Influence on cure rates and risk of second cancer
-
Levinsen M, Rotevatn EO, Rosthoj S, et al. 2014. Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: influence on cure rates and risk of second cancer. Pediatr. Blood Cancer 61:797-802
-
(2014)
Pediatr. Blood Cancer
, vol.61
, pp. 797-802
-
-
Levinsen, M.1
Rotevatn, E.O.2
Rosthoj, S.3
-
33
-
-
0030934850
-
Molecular diagnosis of thiopurine Smethyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
-
Yates CR, Krynetski EY, Loennechen T, et al. 1997. Molecular diagnosis of thiopurine Smethyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. Ann. Intern. Med. 126:608-14
-
(1997)
Ann. Intern. Med.
, vol.126
, pp. 608-614
-
-
Yates, C.R.1
Krynetski, E.Y.2
Loennechen, T.3
-
34
-
-
84862170980
-
Genotyping should be considered the primary choice for pre-Treatment evaluation of thiopurine methyltransferase function
-
Hindorf U, Appell ML. 2012. Genotyping should be considered the primary choice for pre-Treatment evaluation of thiopurine methyltransferase function. J. Crohn's Colitis 6:655-59
-
(2012)
J. Crohn's Colitis
, vol.6
, pp. 655-659
-
-
Hindorf, U.1
Appell, M.L.2
-
35
-
-
33747168764
-
Cost-effectiveness of pharmacogenomics in clinical practice: A case study of thiopurinemethyltransferase genotyping in acute lymphoblastic leukemia in Europe
-
van den Akker-van Marle ME, Gurwitz D, Detmar SB, et al. 2006. Cost-effectiveness of pharmacogenomics in clinical practice: a case study of thiopurinemethyltransferase genotyping in acute lymphoblastic leukemia in Europe. Pharmacogenomics 7:783-92
-
(2006)
Pharmacogenomics
, vol.7
, pp. 783-792
-
-
Van Den Akker-Van Marle, M.E.1
Gurwitz, D.2
Detmar, S.B.3
-
36
-
-
84893549013
-
Development and use of active clinical decision support for preemptive pharmacogenomics
-
Bell GC, Crews KR, Wilkinson MR, et al. 2014. Development and use of active clinical decision support for preemptive pharmacogenomics. J. Am. Med. Inform. Assoc. 21:e93-99
-
(2014)
J. Am. Med. Inform. Assoc.
, vol.21
, pp. e93-99
-
-
Bell, G.C.1
Crews, K.R.2
Wilkinson, M.R.3
-
37
-
-
79951809825
-
CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network
-
Relling MV, Klein TE. 2011. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin. Pharmacol. Ther. 89:464-67
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 464-467
-
-
Relling, M.V.1
Klein, T.E.2
-
38
-
-
84875438476
-
Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update
-
Relling MV, Gardner EE, Sandborn WJ, et al. 2013. Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update. Clin. Pharmacol. Ther. 93:324-25
-
(2013)
Clin. Pharmacol. Ther.
, vol.93
, pp. 324-325
-
-
Relling, M.V.1
Gardner, E.E.2
Sandborn, W.J.3
-
39
-
-
84905185084
-
Chemotherapy-induced peripheral neurotoxicity and ototoxicity: New paradigms for translational genomics
-
In press
-
Travis LB, Fossa SD, Sesso HD, et al. 2014. Chemotherapy-induced peripheral neurotoxicity and ototoxicity: new paradigms for translational genomics. J. Natl. Cancer Inst. In press
-
(2014)
J. Natl. Cancer Inst
-
-
Travis, L.B.1
Fossa, S.D.2
Sesso, H.D.3
-
40
-
-
70649113052
-
Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy
-
Ross CJ, Katzov-Eckert H, Dube MP, et al. 2009. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. Nat. Genet. 41:1345-49
-
(2009)
Nat. Genet.
, vol.41
, pp. 1345-1349
-
-
Ross, C.J.1
Katzov-Eckert, H.2
Dube, M.P.3
-
41
-
-
84880756433
-
Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children
-
Pussegoda K, Ross CJ, Visscher H, et al. 2013. Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children. Clin. Pharmacol. Ther. 94:243-51
-
(2013)
Clin. Pharmacol. Ther.
, vol.94
, pp. 243-251
-
-
Pussegoda, K.1
Ross, C.J.2
Visscher, H.3
-
42
-
-
84880753477
-
The role of inherited TPMT and COMT genetic variation in cisplatin-induced ototoxicity in children with cancer
-
Yang JJ, Lim JY, Huang J, et al. 2013. The role of inherited TPMT and COMT genetic variation in cisplatin-induced ototoxicity in children with cancer. Clin. Pharmacol. Ther. 94:252-59
-
(2013)
Clin. Pharmacol. Ther.
, vol.94
, pp. 252-259
-
-
Yang, J.J.1
Lim, J.Y.2
Huang, J.3
-
43
-
-
84894440389
-
Pharmacogenomic assessment of cisplatin-based chemotherapy outcomes in ovarian cancer
-
Khrunin AV, Khokhrin DV, Moisseev AA, et al. 2014. Pharmacogenomic assessment of cisplatin-based chemotherapy outcomes in ovarian cancer. Pharmacogenomics 15:329-37
-
(2014)
Pharmacogenomics
, vol.15
, pp. 329-337
-
-
Khrunin, A.V.1
Khokhrin, D.V.2
Moisseev, A.A.3
-
45
-
-
84885023351
-
Potential of dihydropyrimidine dehydrogenase genotypes in personalizing 5-fluorouracil therapy among colorectal cancer patients
-
Teh LK, Hamzah S, Hashim H, et al. 2013. Potential of dihydropyrimidine dehydrogenase genotypes in personalizing 5-fluorouracil therapy among colorectal cancer patients. Ther. Drug Monit. 35:624-30
-
(2013)
Ther. Drug Monit.
, vol.35
, pp. 624-630
-
-
Teh, L.K.1
Hamzah, S.2
Hashim, H.3
-
46
-
-
33845219798
-
Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance
-
Morel A, Boisdron-Celle M, Fey L, et al. 2006. Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance. Mol. Cancer Ther. 5:2895-904
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 2895-2904
-
-
Morel, A.1
Boisdron-Celle, M.2
Fey, L.3
-
47
-
-
33947416573
-
5-Fluorouracil-related severe toxicity: A comparison of different methods for the pretherapeutic detection of dihydropyrimidine dehydrogenase deficiency
-
Boisdron-Celle M, Remaud G, Traore S, et al. 2007. 5-Fluorouracil-related severe toxicity: a comparison of different methods for the pretherapeutic detection of dihydropyrimidine dehydrogenase deficiency. Cancer Lett. 249:271-82
-
(2007)
Cancer Lett.
, vol.249
, pp. 271-282
-
-
Boisdron-Celle, M.1
Remaud, G.2
Traore, S.3
-
48
-
-
43749114271
-
Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: A prospective clinical trial by the German 5-FU Toxicity Study Group
-
Schwab M, Zanger UM, Marx C, et al. 2008. Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group. J. Clin. Oncol. 26:2131-38
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2131-2138
-
-
Schwab, M.1
Zanger, U.M.2
Marx, C.3
-
49
-
-
84882236066
-
DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: A meta-Analysis
-
Terrazzino S, Cargnin S, Del ReM, et al. 2013. DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-Analysis. Pharmacogenomics 14:1255-72
-
(2013)
Pharmacogenomics
, vol.14
, pp. 1255-1272
-
-
Terrazzino, S.1
Cargnin, S.2
Del Re, M.3
-
50
-
-
84880506829
-
Fluoropyrimidine toxicity in patientswith dihydropyrimidine dehydrogenase splice site variant: The need for further revision of dose and schedule
-
Magnani E, Farnetti E, Nicoli D, et al. 2013. Fluoropyrimidine toxicity in patientswith dihydropyrimidine dehydrogenase splice site variant: the need for further revision of dose and schedule. Intern. Emerg. Med. 8:417-23
-
(2013)
Intern. Emerg. Med.
, vol.8
, pp. 417-423
-
-
Magnani, E.1
Farnetti, E.2
Nicoli, D.3
-
51
-
-
80052506750
-
Safety, pharmacokinetics (PK), and cost-effectiveness of upfront genotyping of DPYD in fluoropyrimidine therapy
-
Deenen MJ, Cats A, Sechterberger MK, et al. 2011. Safety, pharmacokinetics (PK), and cost-effectiveness of upfront genotyping of DPYD in fluoropyrimidine therapy. ASCO Meet. Abstr. 29:3606
-
(2011)
ASCO Meet. Abstr.
, vol.29
, pp. 3606
-
-
Deenen, M.J.1
Cats, A.2
Sechterberger, M.K.3
-
52
-
-
84888012165
-
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing
-
Caudle KE, Thorn CF, Klein TE, et al. 2013. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing. Clin. Pharmacol. Ther. 94:640-45
-
(2013)
Clin. Pharmacol. Ther.
, vol.94
, pp. 640-645
-
-
Caudle, K.E.1
Thorn, C.F.2
Klein, T.E.3
-
53
-
-
0028276410
-
Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man
-
Bosma PJ, Seppen J, Goldhoorn B, et al. 1994. Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man. J. Biol. Chem. 269:17960-64
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17960-17964
-
-
Bosma, P.J.1
Seppen, J.2
Goldhoorn, B.3
-
54
-
-
0028867826
-
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
-
Bosma PJ, Chowdhury JR, Bakker C, et al. 1995. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N. Engl. J. Med. 333:1171-75
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 1171-1175
-
-
Bosma, P.J.1
Chowdhury, J.R.2
Bakker, C.3
-
55
-
-
33745972934
-
The role of UGT1A128 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer
-
Toffoli G, Cecchin E, Corona G, et al. 2006. The role of UGT1A128 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer. J. Clin. Oncol. 24:3061-68
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 3061-3068
-
-
Toffoli, G.1
Cecchin, E.2
Corona, G.3
-
56
-
-
0031661579
-
UGT1A1 genotypes and glucuronidation of SN-38, the active metabolite of irinotecan
-
Ando Y, Saka H, Asai G, et al. 1998. UGT1A1 genotypes and glucuronidation of SN-38, the active metabolite of irinotecan. Ann. Oncol. 9:845-47
-
(1998)
Ann. Oncol.
, vol.9
, pp. 845-847
-
-
Ando, Y.1
Saka, H.2
Asai, G.3
-
57
-
-
34548598459
-
UGT1A128 genotype and irinotecan-induced neutropenia: Dose matters
-
Hoskins JM, Goldberg RM, Qu P, et al. 2007. UGT1A128 genotype and irinotecan-induced neutropenia: dose matters. J. Natl. Cancer Inst. 99:1290-95
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 1290-1295
-
-
Hoskins, J.M.1
Goldberg, R.M.2
Qu, P.3
-
58
-
-
84862003137
-
Impact of the UGT1A128 allele on response to irinotecan: A systematic review and meta-Analysis
-
Dias MM, McKinnon RA, Sorich MJ. 2012. Impact of the UGT1A128 allele on response to irinotecan: a systematic review and meta-Analysis. Pharmacogenomics 13:889-99
-
(2012)
Pharmacogenomics
, vol.13
, pp. 889-899
-
-
Dias, M.M.1
McKinnon, R.A.2
Sorich, M.J.3
-
59
-
-
84875024320
-
Association between UGT1A128 polymorphisms and clinical outcomes of irinotecan-based chemotherapies in colorectal cancer: A meta-Analysis in Caucasians
-
Liu X, Cheng D, Kuang Q, et al. 2013. Association between UGT1A128 polymorphisms and clinical outcomes of irinotecan-based chemotherapies in colorectal cancer: a meta-Analysis in Caucasians. PLOS ONE 8:e58489
-
(2013)
PLOS ONE
, vol.8
, pp. e58489
-
-
Liu, X.1
Cheng, D.2
Kuang, Q.3
-
60
-
-
79959763841
-
A genotype-directed phase I-IV dose-finding study of irinotecan in combination with fluorouracil/leucovorin as first-line treatment in advanced colorectal cancer
-
Marcuello E, Paez D, Pare L, et al. 2011. A genotype-directed phase I-IV dose-finding study of irinotecan in combination with fluorouracil/leucovorin as first-line treatment in advanced colorectal cancer. Br. J. Cancer 105:53-57
-
(2011)
Br. J. Cancer
, vol.105
, pp. 53-57
-
-
Marcuello, E.1
Paez, D.2
Pare, L.3
-
61
-
-
77649210559
-
Genotype-driven phase i study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer
-
Toffoli G, Cecchin E, Gasparini G, et al. 2010. Genotype-driven phase I study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer. J. Clin. Oncol. 28:866-71
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 866-871
-
-
Toffoli, G.1
Cecchin, E.2
Gasparini, G.3
-
62
-
-
77949755095
-
Phase i study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A128 polymorphism
-
Hazama S, Nagashima A, KondoH, et al. 2010. Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A128 polymorphism. Cancer Sci. 101:722-27
-
(2010)
Cancer Sci.
, vol.101
, pp. 722-727
-
-
Hazama, S.1
Nagashima, A.2
Kondo, H.3
-
63
-
-
79953737378
-
Prospective phase II study of FOLFIRI for mCRC in Japan, including the analysis of UGT1A128/6 polymorphisms
-
Okuyama Y, Hazama S, Nozawa H, et al. 2011. Prospective phase II study of FOLFIRI for mCRC in Japan, including the analysis of UGT1A128/6 polymorphisms. Jpn. J. Clin. Oncol. 41:477-82
-
(2011)
Jpn. J. Clin. Oncol.
, vol.41
, pp. 477-482
-
-
Okuyama, Y.1
Hazama, S.2
Nozawa, H.3
-
64
-
-
79955463893
-
Pharmacogenetics: From bench to byte-An update of guidelines
-
Swen JJ, Nijenhuis M, de Boer A, et al. 2011. Pharmacogenetics: from bench to byte-An update of guidelines. Clin. Pharmacol. Ther. 89:662-73
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 662-673
-
-
Swen, J.J.1
Nijenhuis, M.2
De Boer, A.3
-
65
-
-
84899907375
-
Association between severe toxicity of nilotinib andUGT1A1 polymorphisms in Japanese patients with chronic myelogenous leukemia
-
Shibata T, Minami Y, MitsumaA, et al. 2013. Association between severe toxicity of nilotinib andUGT1A1 polymorphisms in Japanese patients with chronic myelogenous leukemia. Int. J. Clin. Oncol. 19:391-96
-
(2013)
Int. J. Clin. Oncol.
, vol.19
, pp. 391-396
-
-
Shibata, T.1
Minami, Y.2
Mitsuma, A.3
-
66
-
-
35648936586
-
UGT1A1 promoter polymorphism increases risk of nilotinibinduced hyperbilirubinemia
-
Singer JB, Shou Y, Giles F, et al. 2007. UGT1A1 promoter polymorphism increases risk of nilotinibinduced hyperbilirubinemia. Leukemia 21:2311-15
-
(2007)
Leukemia
, vol.21
, pp. 2311-2315
-
-
Singer, J.B.1
Shou, Y.2
Giles, F.3
-
67
-
-
77951666852
-
Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism
-
Xu CF, Reck BH, Xue Z, et al. 2010. Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. Br. J. Cancer 102:1371-77
-
(2010)
Br. J. Cancer
, vol.102
, pp. 1371-1377
-
-
Xu, C.F.1
Reck, B.H.2
Xue, Z.3
-
68
-
-
84887070467
-
Hyperbilirubinemia in pazopanib-or sunitinib-Treated patients in COMPARZ is associated with UGT1A1 polymorphisms
-
Motzer RJ, Johnson T, Choueiri TK, et al. 2013. Hyperbilirubinemia in pazopanib-or sunitinib-Treated patients in COMPARZ is associated with UGT1A1 polymorphisms. Ann. Oncol. 24:2927-28
-
(2013)
Ann. Oncol.
, vol.24
, pp. 2927-2928
-
-
Motzer, R.J.1
Johnson, T.2
Choueiri, T.K.3
-
69
-
-
78651083117
-
The small-molecule tyrosine kinase inhibitor nilotinib is a potent noncompetitive inhibitor of the SN-38 glucuronidation by human UGT1A1
-
Fujita KI, Sugiyama M, Akiyama Y, et al. 2011. The small-molecule tyrosine kinase inhibitor nilotinib is a potent noncompetitive inhibitor of the SN-38 glucuronidation by human UGT1A1. Cancer Chemother. Pharmacol. 67:237-41
-
(2011)
Cancer Chemother. Pharmacol.
, vol.67
, pp. 237-241
-
-
Fujita, K.I.1
Sugiyama, M.2
Akiyama, Y.3
-
70
-
-
49949104757
-
SLCO1B1 variants and statin-induced myopathy-A genomewide study
-
SEARCH Collab. Group.
-
SEARCH Collab. Group. 2008. SLCO1B1 variants and statin-induced myopathy-A genomewide study. N. Engl. J. Med. 359:789-99
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 789-799
-
-
-
71
-
-
84862600938
-
The Clinical Pharmacogenomics Implementation Consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy
-
Wilke RA, Ramsey LB, Johnson SG, et al. 2012. The Clinical Pharmacogenomics Implementation Consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy. Clin. Pharmacol. Ther. 92:112-17
-
(2012)
Clin. Pharmacol. Ther.
, vol.92
, pp. 112-117
-
-
Wilke, R.A.1
Ramsey, L.B.2
Johnson, S.G.3
-
72
-
-
33646014155
-
Rapid identification of three functionally relevant polymorphisms in the OATP1B1 transporter gene using PyrosequencingTM
-
Rohrbacher M, Kirchhof A, Skarke C, et al. 2006. Rapid identification of three functionally relevant polymorphisms in the OATP1B1 transporter gene using PyrosequencingTM. Pharmacogenomics 7:167-76
-
(2006)
Pharmacogenomics
, vol.7
, pp. 167-176
-
-
Rohrbacher, M.1
Kirchhof, A.2
Skarke, C.3
-
73
-
-
59649117206
-
Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-Transporting polypeptide 1B1 (SLCO1B1)
-
van de Steeg E, van der Kruijssen CMM, Wagenaar E, et al. 2009. Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-Transporting polypeptide 1B1 (SLCO1B1). Drug Metab. Dispos. 37:277-81
-
(2009)
Drug Metab. Dispos.
, vol.37
, pp. 277-281
-
-
Van De Steeg, E.1
Van Der Kruijssen, C.M.M.2
Wagenaar, E.3
-
74
-
-
73349098768
-
Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects
-
Trevĩno LR, Shimasaki N, Yang W, et al. 2009. Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J. Clin. Oncol. 27:5972-78
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 5972-5978
-
-
Trevĩno, L.R.1
Shimasaki, N.2
Yang, W.3
-
75
-
-
84873590053
-
Genome-wide study of methotrexate clearance replicates SLCO1B1
-
Ramsey LB, Panetta JC, Smith C, et al. 2013. Genome-wide study of methotrexate clearance replicates SLCO1B1. Blood 121:898-904
-
(2013)
Blood
, vol.121
, pp. 898-904
-
-
Ramsey, L.B.1
Panetta, J.C.2
Smith, C.3
-
76
-
-
84855316334
-
Rare versus commonvariants in pharmacogenetics:SLCO1B1 variation and methotrexate disposition
-
RamseyLB, BruunGH, YangW, et al. 2012. Rare versus commonvariants in pharmacogenetics:SLCO1B1 variation and methotrexate disposition. Genome Res. 22:1-8
-
(2012)
Genome Res.
, vol.22
, pp. 1-8
-
-
Ramsey, L.B.1
Bruun, G.H.2
Yang, W.3
-
77
-
-
84882252168
-
Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia
-
Radtke S, Zolk O, Renner B, et al. 2013. Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia. Blood 121:5145-53
-
(2013)
Blood
, vol.121
, pp. 5145-5153
-
-
Radtke, S.1
Zolk, O.2
Renner, B.3
-
78
-
-
84855968708
-
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype
-
Crews KR, Gaedigk A, DunnenbergerHM, et al. 2012. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin. Pharmacol. Ther. 91:321-26
-
(2012)
Clin. Pharmacol. Ther.
, vol.91
, pp. 321-326
-
-
Crews, K.R.1
Gaedigk, A.2
Dunnenberger, H.M.3
-
79
-
-
77956255908
-
Composite functional genetic and comedication CYP2D6 activity score in predicting tamoxifen drug exposure among breast cancer patients
-
Borges S, Desta Z, Jin Y, et al. 2010. Composite functional genetic and comedication CYP2D6 activity score in predicting tamoxifen drug exposure among breast cancer patients. J. Clin. Pharmacol. 50:450-58
-
(2010)
J. Clin. Pharmacol.
, vol.50
, pp. 450-458
-
-
Borges, S.1
Desta, Z.2
Jin, Y.3
-
80
-
-
84877575399
-
CYP3A4 and seasonal variation in vitamin D status in addition to CYP2D6 contribute to therapeutic endoxifen level during tamoxifen therapy
-
Teft WA, Gong IY, Dingle B, et al. 2013. CYP3A4 and seasonal variation in vitamin D status in addition to CYP2D6 contribute to therapeutic endoxifen level during tamoxifen therapy. Breast Cancer Res. Treat. 139:95-105
-
(2013)
Breast Cancer Res. Treat.
, vol.139
, pp. 95-105
-
-
Teft, W.A.1
Gong, I.Y.2
Dingle, B.3
-
81
-
-
79955485361
-
Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes
-
Madlensky L, Natarajan L, Tchu S, et al. 2011. Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes. Clin. Pharmacol. Ther. 89:718-25
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 718-725
-
-
Madlensky, L.1
Natarajan, L.2
Tchu, S.3
-
82
-
-
84865173799
-
Clinical and biomarker predictors of side effects from tamoxifen
-
LorizioW, WuAB, BeattieM, et al. 2012. Clinical and biomarker predictors of side effects from tamoxifen. Breast Cancer Res. Treat. 132:1107-18
-
(2012)
Breast Cancer Res. Treat.
, vol.132
, pp. 1107-1118
-
-
Lorizio, W.1
Wu, A.B.2
Beattie, M.3
-
83
-
-
84859999600
-
Tamoxifen and CYP2D6: A contradiction of data
-
Hertz DL, McLeod HL, Irvin WJ. 2012. Tamoxifen and CYP2D6: a contradiction of data. Oncologist 17:620-30
-
(2012)
Oncologist
, vol.17
, pp. 620-630
-
-
Hertz, D.L.1
McLeod, H.L.2
Irvin, W.J.3
-
84
-
-
84859093970
-
CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: The Breast International Group 1-98 trial
-
Regan MM, Leyland-Jones B, Bouzyk M, et al. 2012. CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial. J. Natl. Cancer Inst. 104:441-51
-
(2012)
J. Natl. Cancer Inst.
, vol.104
, pp. 441-451
-
-
Regan, M.M.1
Leyland-Jones, B.2
Bouzyk, M.3
-
85
-
-
84859054082
-
CYP2D6 and UGT2B7 genotype and risk of recurrence in tamoxifen-Treated breast cancer patients
-
Rae JM, Drury S, Hayes DF, et al. 2012. CYP2D6 and UGT2B7 genotype and risk of recurrence in tamoxifen-Treated breast cancer patients. J. Natl. Cancer Inst. 104:452-60
-
(2012)
J. Natl. Cancer Inst.
, vol.104
, pp. 452-460
-
-
Rae, J.M.1
Drury, S.2
Hayes, D.F.3
-
86
-
-
80052020634
-
Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: A multicenter study
-
Irvin WJ Jr, Walko CM, Weck KE, et al. 2011. Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study. J. Clin. Oncol. 29:3232-39
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 3232-3239
-
-
Irvin, W.J.1
Walko, C.M.2
Weck, K.E.3
-
87
-
-
84888391516
-
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
-
ToyW, Shen Y, Won H, et al. 2013. ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nat. Genet. 45:1439-45
-
(2013)
Nat. Genet.
, vol.45
, pp. 1439-1445
-
-
Toy, W.1
Shen, Y.2
Won, H.3
-
88
-
-
84888381937
-
Activating ESR1 mutations in hormone-resistant metastatic breast cancer
-
Robinson DR, Wu YM, Vats P, et al. 2013. Activating ESR1 mutations in hormone-resistant metastatic breast cancer. Nat. Genet. 45:1446-51
-
(2013)
Nat. Genet.
, vol.45
, pp. 1446-1451
-
-
Robinson, D.R.1
Wu, Y.M.2
Vats, P.3
-
89
-
-
80051552041
-
The false-positive to false-negative ratio in epidemiologic studies
-
Ioannidis JP, Tarone R, McLaughlin JK. 2011. The false-positive to false-negative ratio in epidemiologic studies. Epidemiology 22:450-56
-
(2011)
Epidemiology
, vol.22
, pp. 450-456
-
-
Ioannidis, J.P.1
Tarone, R.2
McLaughlin, J.K.3
-
90
-
-
79951472909
-
Charting a course for genomic medicine from base pairs to bedside
-
Green ED, Guyer MS, Natl. Hum. Genome Res. Inst. 2011. Charting a course for genomic medicine from base pairs to bedside. Nature 470:204-13
-
(2011)
Nature
, vol.470
, pp. 204-213
-
-
Green, E.D.1
Guyer, M.S.2
Genome Inst.3
-
91
-
-
77953543620
-
Clinical implementation of pharmacogenomics: Overcoming genetic exceptionalism
-
Relling MV, Altman RB, Goetz MP, Evans WE. 2010. Clinical implementation of pharmacogenomics: overcoming genetic exceptionalism. Lancet Oncol. 11:507-9
-
(2010)
Lancet Oncol.
, vol.11
, pp. 507-509
-
-
Relling, M.V.1
Altman, R.B.2
Goetz, M.P.3
Evans, W.E.4
-
92
-
-
84889824971
-
A pharmacogenetic versus a clinical algorithm for warfarin dosing
-
Kimmel SE, French B, Kasner SE, et al. 2013. A pharmacogenetic versus a clinical algorithm for warfarin dosing. N. Engl. J. Med. 369:2283-93
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 2283-2293
-
-
Kimmel, S.E.1
French, B.2
Kasner, S.E.3
-
93
-
-
79951803720
-
Pharmacogenomics noninferiority is sufficient for initial implementation
-
Altman RB. 2011. Pharmacogenomics: 'Noninferiority' is sufficient for initial implementation. Clin. Pharmacol. Ther. 89:348-50
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 348-350
-
-
Altman, R.B.1
-
94
-
-
79951809825
-
CPIC: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network
-
Relling MV, Klein TE. 2011. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin. Pharmacol. Ther. 89:464-67
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 464-467
-
-
Relling, M.V.1
Klein, T.E.2
-
95
-
-
82655184653
-
Personalized oncology through integrative highthroughput sequencing: A pilot study
-
111ra121
-
Roychowdhury S, Iyer MK, Robinson DR, et al. 2011. Personalized oncology through integrative highthroughput sequencing: a pilot study. Sci. Transl. Med. 3:111ra121
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Roychowdhury, S.1
Iyer, M.K.2
Robinson, D.R.3
-
96
-
-
84886286114
-
Variants of unknown significance in BRCA testing: Impact on risk perception, worry, prevention and counseling
-
Richter S, Haroun I, Graham TC, et al. 2013. Variants of unknown significance in BRCA testing: impact on risk perception, worry, prevention and counseling. Ann. Oncol. 24(Suppl 8):viii69-74
-
(2013)
Ann. Oncol.
, vol.24
, pp. viii69-viii74
-
-
Richter, S.1
Haroun, I.2
Graham, T.C.3
-
97
-
-
77951589703
-
Clinical assessment incorporating a personal genome
-
Ashley EA, Butte AJ, Wheeler MT, et al. 2010. Clinical assessment incorporating a personal genome. Lancet 375:1525-35
-
(2010)
Lancet
, vol.375
, pp. 1525-1535
-
-
Ashley, E.A.1
Butte, A.J.2
Wheeler, M.T.3
-
98
-
-
84884494450
-
Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA
-
Rae JM, Regan MM, Thibert JN, et al. 2013. Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA. J. Natl. Cancer Inst. 105:1332-34
-
(2013)
J. Natl. Cancer Inst.
, vol.105
, pp. 1332-1334
-
-
Rae, J.M.1
Regan, M.M.2
Thibert, J.N.3
-
99
-
-
84865486320
-
Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: The Breast International Group 1-98 trial
-
1264; author reply
-
Nakamura Y, Ratain MJ, Cox NJ, et al. 2012. Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial. J. Natl. Cancer Inst. 104:1264; author reply 1266-68
-
(2012)
J. Natl. Cancer Inst.
, vol.104
, pp. 1266-1268
-
-
Nakamura, Y.1
Ratain, M.J.2
Cox, N.J.3
|