Human thiopurine methyltransferase pharmacogenetics. Kindred with a terminal exon splice junction mutation that results in loss of activity

Journal of Clinical Investigation

Volumn 101, Issue 5, 1998, Pages 1036-1044

  Otterness, Diane M ^a   Szumlanski, Carol L ^a   Wood, Thomas C ^a   Weinshilboum, Richard M ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

Genetic polymorphism; Methyltransferase; Pharmacogenetics; RNA processing; Thiopurines

Indexed keywords

MERCAPTOPURINE; METHYLTRANSFERASE; THIOPURINE METHYLTRANSFERASE;

ARTICLE; CLINICAL ARTICLE; ENZYME ANALYSIS; GENE DISRUPTION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; HUMAN CELL; METHYLATION; PHARMACOGENETICS; PRIORITY JOURNAL; REGULATOR GENE; RNA PROCESSING; RNA SPLICING; SPECIES DIFFERENCE;

EID: 0032030953     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1004     Document Type: Article

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