Astragalus and Paeoniae Radix Rubra extract (APE) inhibits hepatic stellate cell activation by modulating transforming growth factor-β/smad pathway

Molecular Medicine Reports

Volumn 11, Issue 4, 2015, Pages 2569-2577

  Huang, Weijuan ^a   Li, Lin ^a   Tian, Xiaopeng ^b   Yan, Jinjin ^a   Yang, Xinzheng ^a   Wang, Xinlong ^a   Liao, Guozhen ^a   Qiu, Genquan ^c  

^a XI'AN MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Astragalus and Paeoniae Radix Rubra extract; Plasminogen activator inhibitor type 1; Transforming growth factor smad pathway; Urokinase type plasminogen activator

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ASTRAGALUS EXTRACT; PAEONIA RADIX; PLASMINOGEN ACTIVATOR INHIBITOR; PROLINE; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UROKINASE; PLANT EXTRACT; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL INVASION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOSE RESPONSE; LIVER; MALE; MTT ASSAY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; WESTERN BLOTTING; ANIMAL; ASTRAGALUS (PLANT); CELL MOTION; CHEMISTRY; DRUG EFFECTS; GENETICS; METABOLISM; PAEONIA; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

BOVINAE; RATTUS;

ANIMALS; ASTRAGALUS PLANT; CELL MOVEMENT; CELL PROLIFERATION; HEPATIC STELLATE CELLS; MALE; PAEONIA; PHOSPHORYLATION; PLANT EXTRACTS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84921378221     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.3026     Document Type: Article

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