Ameliorative effect of grape seed proanthocyanidin extract on thioacetamide-induced mouse hepatic fibrosis

Toxicology Letters

Volumn 213, Issue 3, 2012, Pages 353-360

  Li, Jie ^b   Li, Jun ^b   Li, Sha ^b   He, Bin ^b   Mi, Yuling ^b   Cao, Hongcui ^a   Zhang, Caiqiao ^a,b   Li, Lanjuan ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Anti inflammatory; Antioxidant; Grape seed proanthocyanidin extract; Hepatic stellate cell; Liver fibrosis; Thioacetamide

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; CYCLOOXYGENASE 2; GRAPE SEED EXTRACT; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; PROANTHOCYANIDIN DERIVATIVE; THIOACETAMIDE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; FEMALE; LIVER FIBROSIS; LIVER PROTECTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME;

ACTINS; ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; COLLAGEN TYPE I; CYCLOOXYGENASE 2; CYTOPROTECTION; FEMALE; GENE EXPRESSION REGULATION; GRAPE SEED EXTRACT; HEPATIC STELLATE CELLS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; LIPID PEROXIDATION; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MICE; MICE, INBRED ICR; NECROSIS; NITRIC OXIDE SYNTHASE TYPE II; PROANTHOCYANIDINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THIOACETAMIDE; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

MUS; VITACEAE;

EID: 84865322468     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.07.019     Document Type: Article

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