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Volumn 27, Issue 5, 2013, Pages 731-736

Protective effects of a purified saponin mixture from astragalus corniculatus Bieb., in vivo hepatotoxicity models

Author keywords

CCl4; liver toxicity; paracetamol; saponins

Indexed keywords

19ALPHA HYDROXYOLEAN 12 ENE 28,21BETA OLIDE 3 BETA XYLOPYRANOSIDE; 21ALPHA HYDROXYOLEAN 12 ENE 28 OIC ACID 3BETA 4 OXOPENTOPYRANOSIDE; 3BETA O [O 4 OXOPENTOPYRANOSYL (1-2) BETA GLUCOPYRANOSYL] 21ALPHA HYDROXYOLEAN 12 ENE 28 OIC ACID; ALANINE AMINOTRANSFERASE; ANILINE 4 HYDROXYLASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CYTOCHROME P450; ETHYLMORPHINE N DEMETHYLASE; GLUTATHIONE; LACTATE DEHYDROGENASE; MALONALDEHYDE; OXYGENASE; PARACETAMOL; SAPONIN; SILYMARIN; UNCLASSIFIED DRUG;

EID: 84876466879     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4785     Document Type: Article
Times cited : (21)

References (28)
  • 1
    • 34547632384 scopus 로고    scopus 로고
    • Propolis protects CYP 2E1 enzymatic activity and oxidative stress induced by carbontetrachloride
    • Bhadauria M, Nirala SM, Shukla S,. 2007. Propolis protects CYP 2E1 enzymatic activity and oxidative stress induced by carbontetrachloride. Mol Cell Biochem 302: 215-224.
    • (2007) Mol Cell Biochem , vol.302 , pp. 215-224
    • Bhadauria, M.1    Nirala, S.M.2    Shukla, S.3
  • 2
    • 0020679091 scopus 로고
    • Role of glutathione in the hypoxic cell cytotoxicity of misonidazole
    • Bump EA, Taylor YC, Brown MJ,. 1983. Role of glutathione in the hypoxic cell cytotoxicity of misonidazole. Cancer Res 43: 997-1002.
    • (1983) Cancer Res , vol.43 , pp. 997-1002
    • Bump, E.A.1    Taylor, Y.C.2    Brown, M.J.3
  • 3
    • 0029264464 scopus 로고
    • Effects of Astragalus membrenaceous on left ventricular function and oxygen free radical in acute myocardial infarction patients and mechanism of its cardiotonic action
    • Chen L, Liao J, Guo W,. 1995. Effects of Astragalus membrenaceous on left ventricular function and oxygen free radical in acute myocardial infarction patients and mechanism of its cardiotonic action. Chung Kuo Chung Hsil Chien Ho Tsa Chih 15: 141-143.
    • (1995) Chung Kuo Chung Hsil Chien Ho Tsa Chih , vol.15 , pp. 141-143
    • Chen, L.1    Liao, J.2    Guo, W.3
  • 4
    • 67651249826 scopus 로고    scopus 로고
    • Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P 450 suppression
    • Chen X, Sun C, Han G, et al,. 2009. Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P 450 suppression. World J Gastroenterol 15: 1829-1835.
    • (2009) World J Gastroenterol , vol.15 , pp. 1829-1835
    • Chen, X.1    Sun, C.2    Han, G.3
  • 5
    • 0034428256 scopus 로고    scopus 로고
    • Equally potent inhibitors of cholesterol synthesis in human hepatocytes have distinguishable effects on different cytochrome P 450 enzymes
    • Cohen LH, van Leeuwen REW, van Thiel GCF, van Pelt JF, Yap SH,. 2000. Equally potent inhibitors of cholesterol synthesis in human hepatocytes have distinguishable effects on different cytochrome P 450 enzymes. Biopharm Drug Dispos 21: 353-364.
    • (2000) Biopharm Drug Dispos , vol.21 , pp. 353-364
    • Cohen, L.H.1    Van Leeuwen, R.E.W.2    Van Thiel, G.C.F.3    Van Pelt, J.F.4    Yap, S.H.5
  • 7
    • 78650521620 scopus 로고    scopus 로고
    • Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities
    • Doehmer J, Weiss G, McGregor GP, Appel K,. 2011. Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities. Toxicol In Vitro 25: 21-27.
    • (2011) Toxicol in Vitro , vol.25 , pp. 21-27
    • Doehmer, J.1    Weiss, G.2    McGregor, G.P.3    Appel, K.4
  • 8
    • 0033984466 scopus 로고    scopus 로고
    • Elevated type 1, diminished type 2 cytokines and impaired antibody response are associated with hepatotoxicity and mortalities during Shistosoma mansoni infection of CD depleted mice
    • Fallon P, Richardson EJ, Smith P, Dune DW,. 2000. Elevated type 1, diminished type 2 cytokines and impaired antibody response are associated with hepatotoxicity and mortalities during Shistosoma mansoni infection of CD depleted mice. Eur J Immunol 30: 470-480.
    • (2000) Eur J Immunol , vol.30 , pp. 470-480
    • Fallon, P.1    Richardson, E.J.2    Smith, P.3    Dune, D.W.4
  • 9
    • 0001818451 scopus 로고
    • Microsomal enzymes involved in toxicology. Analysis and separation
    • In, Heis A.W. (ed). Raven Press: New York (NY)
    • Guengerich FP,. 1987. Microsomal enzymes involved in toxicology. Analysis and separation. In Principals and Methods of Toxicology, Heis AW, (ed). Raven Press: New York (NY); 609-634.
    • (1987) Principals and Methods of Toxicology , pp. 609-634
    • Guengerich, F.P.1
  • 10
    • 84871887254 scopus 로고    scopus 로고
    • Pharmacological activities and biologically active compounds of Bulgarian medicinal plants
    • In, Filippo I. (ed). Kerala: India
    • Ivancheva S, Nikolova M, Tsvetkova R,. 2006. Pharmacological activities and biologically active compounds of Bulgarian medicinal plants. In Phytochemistry: Advances in Research, Filippo I, (ed). Kerala: India; 87-103.
    • (2006) Phytochemistry: Advances in Research , pp. 87-103
    • Ivancheva, S.1    Nikolova, M.2    Tsvetkova, R.3
  • 12
    • 0025140667 scopus 로고
    • Effect of Melothria maderaspatana on carbontetrachloride-induced changes in rat hepatic microsomal drug-metabolizing enzyme activity
    • Jayatilaka KA, Thabrew MI, Perara DJ,. 1990. Effect of Melothria maderaspatana on carbontetrachloride-induced changes in rat hepatic microsomal drug-metabolizing enzyme activity. J Ethnopharmacol 48: 89-97.
    • (1990) J Ethnopharmacol , vol.48 , pp. 89-97
    • Jayatilaka, K.A.1    Thabrew, M.I.2    Perara, D.J.3
  • 13
    • 34547728246 scopus 로고    scopus 로고
    • A new saponin lactone from Astragalus corniculatus
    • Krasteva I, Nikolov S, Kaloga M,. 2007. A new saponin lactone from Astragalus corniculatus. Nat Prod Res 21: 941-945.
    • (2007) Nat Prod Res , vol.21 , pp. 941-945
    • Krasteva, I.1    Nikolov, S.2    Kaloga, M.3
  • 14
    • 33750370849 scopus 로고    scopus 로고
    • Triterpenoid saponins from Astragalus corniculatus
    • Krasteva I, Nikolov S, Kaloga M, Mayer G,. 2006. Triterpenoid saponins from Astragalus corniculatus. Z Naturforsch 61b: 1166-1169.
    • (2006) Z Naturforsch , vol.61 B , pp. 1166-1169
    • Krasteva, I.1    Nikolov, S.2    Kaloga, M.3    Mayer, G.4
  • 15
    • 3242715045 scopus 로고    scopus 로고
    • Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity
    • Krasteva I, Nikolova I, Danchev N, Nikolov S,. 2004. Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity. Acta Pharm 54: 151-156.
    • (2004) Acta Pharm , vol.54 , pp. 151-156
    • Krasteva, I.1    Nikolova, I.2    Danchev, N.3    Nikolov, S.4
  • 16
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • Lowry OH,. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1
  • 17
    • 76749153122 scopus 로고    scopus 로고
    • Effect of purified saponin mixture from Astragalus corniculatus on toxicity models in isolated rat hepatocytes
    • Mitcheva M, Kondeva-Burdina M, Vitcheva V, Krasteva I, Nikolov S,. 2008. Effect of purified saponin mixture from Astragalus corniculatus on toxicity models in isolated rat hepatocytes. Pharm Biology 12: 866-870.
    • (2008) Pharm Biology , vol.12 , pp. 866-870
    • Mitcheva, M.1    Kondeva-Burdina, M.2    Vitcheva, V.3    Krasteva, I.4    Nikolov, S.5
  • 18
    • 33846345425 scopus 로고    scopus 로고
    • Protective effect of silymarin on oxidative stress in rat brain
    • Nencini C, Giorgi G, Micheli L,. 2007. Protective effect of silymarin on oxidative stress in rat brain. Phytomedicine 14: 129-135.
    • (2007) Phytomedicine , vol.14 , pp. 129-135
    • Nencini, C.1    Giorgi, G.2    Micheli, L.3
  • 19
    • 78651165715 scopus 로고
    • The carbon-monoxide-binding pigment of liver microsomes
    • Omura T, Sato R,. 1964. The carbon-monoxide-binding pigment of liver microsomes. J Biol Chem 239: 2370-2385.
    • (1964) J Biol Chem , vol.239 , pp. 2370-2385
    • Omura, T.1    Sato, R.2
  • 20
    • 9144226514 scopus 로고    scopus 로고
    • Secondary metabolites of genus Astragalus: Structure and biological activity
    • In, Atta-Ur-Rahman (ed). Elsevier Science B.V: Karachi
    • Pistelli L,. 2002. Secondary metabolites of genus Astragalus: Structure and biological activity. In Studies in Natural Products Chemistry (Bioactive Natural Products, Part H), Atta-Ur-Rahman, (ed). Elsevier Science B.V: Karachi; 443-545.
    • (2002) Studies in Natural Products Chemistry (Bioactive Natural Products, Part H) , pp. 443-545
    • Pistelli, L.1
  • 21
    • 13844266765 scopus 로고    scopus 로고
    • Effects of angiotensin II type 1 receptor blockade on the oxidative stress in spontaneously hypertensive rat tissues
    • Polizio AH, Pena C,. 2005. Effects of angiotensin II type 1 receptor blockade on the oxidative stress in spontaneously hypertensive rat tissues. Regul Pept 128: 1-5.
    • (2005) Regul Pept , vol.128 , pp. 1-5
    • Polizio, A.H.1    Pena, C.2
  • 22
    • 0030797894 scopus 로고    scopus 로고
    • A review of the pharmacology and toxicology of Astragalus
    • Rios J, Waterman P,. 1997. A review of the pharmacology and toxicology of Astragalus. Phytother Res 14: 411-418.
    • (1997) Phytother Res , vol.14 , pp. 411-418
    • Rios, J.1    Waterman, P.2
  • 23
    • 0034029088 scopus 로고    scopus 로고
    • Effect of food restriction on hepatotoxicity of carbontetrachloride in rats
    • Seki M, Kasama K, Imai K,. 2000. Effect of food restriction on hepatotoxicity of carbontetrachloride in rats. J Toxicol Sci 25: 33-40.
    • (2000) J Toxicol Sci , vol.25 , pp. 33-40
    • Seki, M.1    Kasama, K.2    Imai, K.3
  • 24
    • 76749125275 scopus 로고    scopus 로고
    • Effect of purified saponin mixture from Astragalus corniculatus on enzyme- and nonenzyme-induced lipid peroxidation in liver microsomes from spontaneously hypertensive rats and normotensive rats
    • Simeonova R, Vitcheva V, Kondeva-Burdina M, Krasteva I, Nikolov S, Mitcheva M,. 2010. Effect of purified saponin mixture from Astragalus corniculatus on enzyme- and nonenzyme-induced lipid peroxidation in liver microsomes from spontaneously hypertensive rats and normotensive rats. Phytomedicine 17: 346-349.
    • (2010) Phytomedicine , vol.17 , pp. 346-349
    • Simeonova, R.1    Vitcheva, V.2    Kondeva-Burdina, M.3    Krasteva, I.4    Nikolov, S.5    Mitcheva, M.6
  • 25
    • 84871274443 scopus 로고    scopus 로고
    • Factors affecting metabolism and disposition - Toxic responses to foreign compounds - Direct toxic action: Tissue lesions
    • In, 3rd Edition; Taylor and Francis: London
    • Timbrell J,. 2000. Factors affecting metabolism and disposition-Toxic responses to foreign compounds-direct toxic action: tissue lesions. In Principles of Biochemical Toxicology, 3rd Edition; Taylor and Francis: London; 176-211.
    • (2000) Principles of Biochemical Toxicology , pp. 176-211
    • Timbrell, J.1
  • 26
    • 0024455859 scopus 로고
    • Selectivity of silymarin on the increase of the glutathione content in different tissues of the rat
    • Valenzuela A, Aspillaga M, Vial S, et al,. 1989. Selectivity of silymarin on the increase of the glutathione content in different tissues of the rat. Planta Med 55: 420-2.
    • (1989) Planta Med , vol.55 , pp. 420-422
    • Valenzuela, A.1    Aspillaga, M.2    Vial, S.3
  • 27
    • 0030310778 scopus 로고    scopus 로고
    • Protective effect of active components extracted from radix Astragali on human erythrocyte membrane damages caused by reactive oxygen species
    • Wang D, Shen W, Tian Y, Sun Z, Jiang C, Yuan S,. 1996. Protective effect of active components extracted from radix Astragali on human erythrocyte membrane damages caused by reactive oxygen species. Zhongguo Zhong Yao Za Zhi 21: 746-763.
    • (1996) Zhongguo Zhong Yao Za Zhi , vol.21 , pp. 746-763
    • Wang, D.1    Shen, W.2    Tian, Y.3    Sun, Z.4    Jiang, C.5    Yuan, S.6
  • 28
    • 79955047016 scopus 로고    scopus 로고
    • Oral administration of Trapa taiwanensis Nakai fruit skin extracts conferring hepatoprotection from CCl4-caused injury
    • Wang SH, Kao MY, Wu SC, et al,. 2011. Oral administration of Trapa taiwanensis Nakai fruit skin extracts conferring hepatoprotection from CCl4-caused injury. J Agric Food Chem 59: 3686-92.
    • (2011) J Agric Food Chem , vol.59 , pp. 3686-3692
    • Wang, S.H.1    Kao, M.Y.2    Wu, S.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.