Stat3 signaling activation crosslinking of TGF-β1 in hepatic stellate cell exacerbates liver injury and fibrosis

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1842, Issue 11, 2014, Pages 2237-2245

  Xu, Ming Yi ^a   Hu, Jun Jie ^a   Shen, Jie ^a   Wang, Mei Ling ^a   Zhang, Qing Qing ^a   Qu, Ying ^a   Lu, Lun Gen ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Hepatic stellate cell; Liver fibrosis; Signal transducer and activator of transcription 3; Transforming growth factor 1

Indexed keywords

BETA ACTIN; CASPASE 3; CHECKPOINT KINASE 1; INTERLEUKIN 6; PROTEIN BCL 2; SMAD PROTEIN; STAT3 PROTEIN; SURVIVIN; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CHRONIC HEPATITIS; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; EXPERIMENTAL LIVER FIBROSIS; EXPERIMENTAL LIVER INJURY; FIBROGENESIS; G2 PHASE CELL CYCLE CHECKPOINT; HEPATITIS B; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STELLATE CELL; UPREGULATION;

EID: 84908077833     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.07.025     Document Type: Article

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