Graptopetalum Paraguayense Ameliorates Chemical-Induced Rat Hepatic Fibrosis In Vivo and Inactivates Stellate Cells and Kupffer Cells In Vitro

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Su, Li Jen ^a   Chang, Chia Chuan ^b   Yang, Chih Hsueh ^c   Hsieh, Shur Jong ^c   Wu, Yi Chin ^c   Lai, Jin Mei ^d   Tseng, Tzu Ling ^e   Huang, Chi Ying F ^f   Hsu, Shih Lan ^c  

^a NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^e INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE   (Taiwan)

^f NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; CASPASE 2; CASPASE 3; CASPASE 8; CASPASE 9; COLLAGEN TYPE 1; DIMETHYLNITROSAMINE; GRAPTOPETALUM PARAGUAYENSE EXTRACT; HYDROXYPROLINE; INTERLEUKIN 10; INTERLEUKIN 6; NITRIC OXIDE; PLANT EXTRACT; PROTHROMBIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME ACTIVITY; GRAPTOPETALUM PARAGUAYENSE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KUPFFER CELL; LIVER FIBROSIS; LIVER PROTECTION; MALE; MEDICINAL PLANT; MORTALITY; NONHUMAN; PROTEIN EXPRESSION; RAT; STELLATE CELL; TOXIC HEPATITIS; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BODY WEIGHT; CYTOKINES; DIMETHYLNITROSAMINE; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; FERNS; HEPATIC STELLATE CELLS; INFLAMMATION; KUPFFER CELLS; LIVER; LIVER CIRRHOSIS; MALE; ORGAN SIZE; PLANT EXTRACTS; RATS; SPLEEN;

GRAPTOPETALUM PARAGUAYENSE; RATTUS;

EID: 84872374700     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053988     Document Type: Article

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