Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1

Journal of Biological Chemistry

Volumn 286, Issue 9, 2011, Pages 7027-7032

  Lin, Zhonghui ^a,b   Jiang, Longguang ^a,b   Yuan, Cai ^a,b,d   Jensen, Jan K ^b,c   Zhang, Xu ^a,b   Luo, Zhipu ^a,b   Furie, Barbara C ^d   Furie, Bruce ^d   Andreasen, Peter A ^b,c   Huang, Mingdong ^a,b,d  

^a FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER   (China)

^b Danish Chinese Centre for Proteases and Cancer   (China)

^c AARHUS UNIVERSITY   (Denmark)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CATALYTIC SITES; CELL MIGRATION; CONTACT AREAS; MICHAELIS COMPLEX; PLASMINOGEN ACTIVATOR INHIBITOR-1; PROGNOSTIC FACTORS; REACTIVE CENTER LOOPS; STRUCTURAL BASIS; STRUCTURAL MECHANISMS; TECHNICAL DIFFICULTIES; TISSUE REMODELING; UROKINASE-TYPE PLASMINOGEN ACTIVATOR; UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA);

CYTOLOGY;

CRYSTAL STRUCTURE;

PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

ARTICLE; CELL MIGRATION; CHEMICAL INTERACTION; CHEMICAL REACTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STRUCTURE; FIBRINOLYSIS; MICHAELIS CONSTANT; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY; ENZYME ACTIVATION; HUMANS; MUTATION; PICHIA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 79953190056     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.204537     Document Type: Article

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