Transgalactosylation and hydrolytic activities of commercial preparations of β-galactosidase for the synthesis of prebiotic carbohydrates

Enzyme and Microbial Technology

Volumn 70, Issue , 2015, Pages 9-17

  Guerrero, Cecilia ^a   Vera, Carlos ^a   Conejeros, Raúl ^a   Illanes, Andrés ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO   (Chile)

Author keywords

Fructosyl galacto oligosaccharides; Galacto oligosaccharides; Lactulose; Prebiotic carbohydrates; Galactosidase

Indexed keywords

BACTERIOLOGY; CARBOHYDRATES; ENZYMES; SUGARS;

GALACTO-OLIGOSACCHARIDES; GALACTOSIDASES; HYDROLYTIC ACTIVITIES; LACTOSE-DERIVED OLIGOSACCHARIDES; LACTULOSE; MICHAELIS CONSTANTS; PREBIOTICS; TRANSGALACTOSYLATION;

OLIGOSACCHARIDES;

BETA GALACTOSIDASE; CARBOHYDRATE; FRUCTOSYL GALACTO OLIGOSACCHARIDE; FUNGAL ENZYME; GALACTOSE OLIGOSACCHARIDE; HYDROLASE; LACTULOSE; PREBIOTIC AGENT; UNCLASSIFIED DRUG; FRUCTOSE; GALACTOSE; LACTOSE; OLIGOSACCHARIDE;

ARTICLE; ASPERGILLUS ACULEATUS; ASPERGILLUS ORYZAE; BACILLUS CIRCULANS; CATALYST; COMMERCIAL SPECIES; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME ISOLATION; ENZYME MECHANISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; KLUYVEROMYCES LACTIS; MICHAELIS CONSTANT; NONHUMAN; PROTEIN CONTENT; PROTEIN DETERMINATION; SYNTHESIS; TRANSGALACTOSYLATION; BACILLUS; BIOSYNTHESIS; BIOTECHNOLOGY; ENZYMOLOGY; GLYCOSYLATION; ISOLATION AND PURIFICATION; KINETICS; KLUYVEROMYCES; METABOLISM; SPECIES DIFFERENCE;

BACILLUS CIRCULANS; KLUYVEROMYCES;

ASPERGILLUS ORYZAE; BACILLUS; BETA-GALACTOSIDASE; BIOTECHNOLOGY; CARBOHYDRATES; FRUCTOSE; GALACTOSE; GLYCOSYLATION; HYDROLYSIS; KINETICS; KLUYVEROMYCES; LACTOSE; LACTULOSE; OLIGOSACCHARIDES; PREBIOTICS; SPECIES SPECIFICITY;

EID: 84921309693     PISSN: 01410229     EISSN: 18790909     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2014.12.006     Document Type: Article

References (51)

1. Huber R.E., Kurz G., Wallenfels K. Quantitation of the factors which affect the hydrolase and transgalactosylase activities of β-galactosidase (E. coli) on lactose. Biochemistry 1976, 15:1994-2001.
2. Prenosil J.E., Stuker E., Bourne J.R. Formation of oligosaccharides during enzymatic hydrolysis of lactose-part 1: state of art. Biotechnol Bioeng 1987, 30:1019-1025.
3. Ansari S.A., Satar R. Recombinant β-galactosidase-past, present and future: a mini review. J Mol Catal, B: Enzym 2010, 81:1-6.
4. Husain Q. β-Galactosidase and their applications: a review. Crit. Rev. Biotechnol. 2010, 30:41-62.
5. Panesar P., Kumari S., Panesar R. Potential applications of immobilized β-galactosidase in food processing industries. Enzyme Res 2010, 2010:1-16.
6. Vera C., Guerrero C., Illanes A. Determination of the transgalactosylation activity of Aspergillus oryzae β-galactosidase: effect of pH, temperature, and galactose and glucose concentrations. Carbohydr Res 2011, 346:745-752.
7. Albayrak N., Yang S.T. Production of galacto-oligosaccharides from lactose by Aspergillus oryzae β-galactosidase immobilized on cotton cloth. Biotechnol Bioeng 2002, 77:8-19.
8. Kim Y.S., Park C.S., Oh D.K. Lactulose production from lactose and fructose by a thermostable β-galactosidase from Sulfolobus solfataricus. Enzyme Microb Technol 2006, 39:903-908.
9. Li W., Xiang X., Tang S., Hu B., Tian L., Sun Y., et al. Effective enzymatic synthesis of lactosucrose and its analogues by β-galactosidase from Bacillus circulans. J Agric Food Chem 2009, 57:3927-3933.
10. Gänzle M., Haase G., Jelen P. Lactose: crystallization, hydrolysis and value-added derivatives. Int Dairy J 2008, 18:685-694.
11. Stevenson D.E., Stanley R.A., Furneaux R.H. Optimization of alkyl-d galactopyranoside synthesis from lactose using commercially available β-galactosidases. Biotechnol Bioeng 1993, 42:657-666.
12. Klewicki R. Transglycosylation of a β-galactosyl radical, in the course of enzymic hydrolysis of lactose, in the presence of selected polyhydroxyalcohols. Biotechnol Lett 2000, 22:1063-1066.
13. Irazoqui G., Giacomini C., Batista-Viera F., Brena B.M., Cardelle-Cobas A., Corzo N., et al. Characterization of galactosyl derivatives obtained by transgalactosylation of lactose and different polyols using immobilized β-galactosidase from Aspergillus oryzae. J Agric Food Chem 2009, 57:11302-11307.
14. Panesar P.S., Kumari S. Lactulose: production, purification and potential applications. Biotech Adv 2011, 29:940-948.
15. Guerrero C., Vera C., Plou F., Illanes A. Influence of reaction conditions on the selectivity of the synthesis of lactulose with microbial β-galactosidases. J Mol Catal, B: Enzym 2011, 72:206-212.
16. Martínez-Villaluenga C., Cardelle-Cobas A., Corzo N., Olano A., Villamiel M., Jimeno M.L. Enzymatic synthesis and identification of two trisaccharides produced from lactulose by transgalactosylation. J Agric Food Chem 2008, 56:557-563.
17. Olano A., Corzo N. Lactulose as a food ingredient. J Sci Food Agric 2009, 89:1987-1990.
18. Cardelle-Cobas A., Martinez-Villaluenga C., Villamiel M., Olano A., Corzo N. Synthesis of oligosaccharides derived from lactulose and Pectinex Ultra SP-L. J Agric Food Chem 2008, 56:3328-3333.
19. Guerrero C., Vera C., Illanes A. Optimisation of synthesis of oligosaccharides derived from lactulose (fructosyl-galacto-oligosaccharides) with β-galactosidases of different origin. Food Chem 2013, 138:2225-2232.
20. Lee Y.J., Kim C.S., Oh D.K. Lactulose production by β-galactosidase impermeabilized cells of Kluyveromyces lactis. Appl Microbiol Biotechnol 2004, 64:787-793.
21. Duarte P.M., Goncalves M.P., Teixeira J.A., Rodrigues L.R. Galacto-oligosaccharides: production, properties, applications, and significance as prebiotics. Compre Rev Food Sci Food Saf 2010, 9:438-454.
22. Gosling A., Stevens G.W., Barber A.R., Kentish S.E., Gras S.L. Recent advances refining galactooligosaccharide production from lactose. Food Chem 2010, 121:307-318.
23. Schuster-Wolff-Bühring R., Fischer L., Hinrichs J. Production and physiological action of the disaccharide lactulose. Int Dairy J 2010, 20:731-741.
24. Nakayama T., Amachi T. Bioprocess technology fermentation, biocatalysis and bioseparation 1999, 1291-1305. John Wiley & Sons, Inc., New York, NY.
25. Sanz Valero J.I. Production of galacto-oligosaccharides from lactose by immobilized β-galactosidase and posterior chromatographic separation 2009, The Ohio State University, Ohio, USA, (Ph.D. Degree Dissertation).
26. Boon M.A., Janssen A.E.M., van der Padt A. Modelling and parameter estimation of the enzymatic synthesis of oligosaccharides by β-galactosidase from Bacillus circulans. Biotechnol Bioeng 1999, 64:558-567.
27. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
28. Jurado E., Camacho F., Luzón G., Vicaria J.M. Kinetic models of activity for β-galactosidases: influence of pH, ionic concentration and temperature. Enzyme Microb Technol 2004, 34:33-40.
29. Samoshina N.M., Samoshin V.V. The Michaelis constants ratio for two substrates with a series of fungal (mould and yeast) β-galactosidases. Enzyme Microb Technol 2005, 36:239-251.
30. Mlichová Z., Rosenberg M. Current trends of β-galactosidase application in food technology. J Food Nutr Res 2006, 45:47-54.
31. Otieno D. Synthesis of β-galactooligoccharides from lactose using microbial β-galactosidases. Compre Rev Food Sci Food Saf 2010, 9:471-482.
32. Harju M., Kallioinen H., Tossavainen O. Lactose hydrolysis and other conversions in dairy products: technological aspects. Int Dairy J 2012, 22:104-109.
33. Puupponen-Pimiä R., Ivohynek L., Ammann S., Oksman-Caldentey K-M., Buchert J. Enzyme-assisted processing increases antimicrobial and antioxidant activity of billberry. J Agric Food Chem 2008, 56:681-688.
34. Pereira-Rodríguez A., Fernández-Leiro R., González-Siso M.I., Cerdán M.E., Becerra M., Sanz-Aparicio J. Structural basis of specificity in tetrameric Kluyveromyces lactis β-galactosidase. J Struct Biol 2012, 177:392-401.
35. Rodriguez-Colinas B., de Abreu M.A., Fernandez-Arrojo L., de Beer R., Poveda A., Jimenez-Barbero J., et al. Production of galacto-oligosaccharides by the β-galactosidase from Kluyveromyces lactis: Comparative analysis of permeabilized cells versus soluble enzyme. J Agric Food Chem 2011, 59:10477-10484.
36. Padilla B., Ruiz-Matute A.I., Belloch C., Cardelles-Cobas A., Corzo N., Manzanares P. Evaluation of oliogosaccharide synthesis from lactose and lactulose using β-galactosidases from Kluyveromyces isolated from artisanal cheeses. J Agric Food Chem 2012, 60:5134-5141.
37. Cardelle-Cobas A., Villamiel M., Olano A., Corzo N. Study of galacto-oligosaccharide formation from lactose using Pectinex Ultra SP-L. J Sci Food Agric 2008, 88:954-961.
38. Toba T., Adachi S. Hydrolysis of lactose by microbial β-galactosidases. Formation of oligosaccharides with special reference to 2-O-β-d-galactopyranosyl-d-glucose. J Dairy Sci 1978, 61:33-38.
39. Díez-Municio M., Herrero M., Olano A., Moreno F.J. Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases. Microb Biotechnol 2014, 7:315-331.
40. Corzo-Martínez M., Copoví P., Olano A., Moreno F.J., Montilla A. Synthesis of prebiotic carbohydrates derived from cheese whey permeate by a combined process of isomerization and transgalactosylation. J Sci Food Agric 2013, 93:1591-1597.
41. Vera C., Guerrero C., Conejeros R., Illanes A. Synthesis of galacto-oligosaccharides by β-galactosidase from Aspergillus oryzae using partially dissolved and supersaturated solution of lactose. Enzyme Microb Technol 2012, 50:188-194.
42. Irazoqui G., Bustamante M.J., Castilla A., Villagrán L.V., Batista-Viera F., Brena B.M., et al. Substrate-like inhibition of the transgalactosylation reaction catalyzed by β-galactosidase for Aspergillus oryzae. Biocatal Biotransform 2013, 31:57-65.
43. Urrutia P., Mateo C., Guisan J.M., Wilson L., Illanes A. Immobilization of Bacillus circulans β-galactosidase and its application in the synthesis of galacto-oligosaccharides under repeated-batch operation. Biochem Eng J 2014, 77:41-48.
44. Rodriguez-Colinas B., Poveda A., Jimenez-Barbero J., Ballesteros A., Plou F.J. Galacto-oligosaccharides synthesis from lactose solution or skim milk using the β-galactosidase from Bacillus circulans. J Agric Food Chem 2012, 60:6391-6398.
45. Mozaffar Z., Nakanishi K., Matsuno R. Purification and properties of β-galactosidases from Bacillus circulans. Agric Biol Chem 1984, 48:3053-3061.
46. Warmerdam A., Paudel E., Jia W., Boom R.M., Janssen A.E. Characterization of β-galactosidase isoforms from Bacillus circulans and their contribution to GOS production. Appl Biochem Biotechnol 2013, 170:340-358.
47. Jurado E., Camacho F., Luzón G., Vicaria J.M. A new kinetic model proposed for enzymatic hydrolysis of lactose by a β-galactosidase from Kluyveromyces fragilis. Enzyme Microb Technol 2002, 31:300-309.
48. Urrutia P., Rodriguez-Colinas B., Fernandez-Arrojo L., Ballesteros A., Wilson L., Illanes A., et al. Detailed analysis of galacto-oligosaccharides synthesis with β-galactosidases from Aspergillus oryzae. J Agric Food Chem 2013, 61:1081-1087.
49. Cardelle-Cobas A., Olano A., Corzo N., Villamiel M., Colins M., Kolida S., et al. In vitro fermentation of lactulose-derived oligosaccharides by mixed feacal microbiota. J Agric Food Chem 2012, 60:2014-2032.
50. Hernández-Hernández O., Montañes F., Clemente A., Moreno F.J., Sanz M.L. Characterization of galactooligosaccharides derived from lactulose. J Chromatogr A 2011, 1218:7691-7696.
51. Cardelle-Cobas A., Corzo N., Martínez-Villaluenga C., Olano A. Effect of reaction condictions on lactulose-derived trisaccharides obtained by transgalactosylation with β-galactosidase of Kluyveromyces lactis. Eur Food Res Technol 2011, 233:89-94.