Molecular basis for self-assembly of a human host-defense peptide that entraps bacterial pathogens

Journal of the American Chemical Society

Volumn 136, Issue 38, 2014, Pages 13267-13276

  Chairatana, Phoom ^a   Nolan, Elizabeth M ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; BIOACTIVITY; DISEASES; ESCHERICHIA COLI; HYDROPHOBICITY; LISTERIA; MAMMALS; PATHOGENS; PEPTIDES; TRANSMISSION ELECTRON MICROSCOPY;

ANTI-BACTERIAL ACTIVITY; ANTIMICROBIAL PEPTIDE; BIOPHYSICAL CHARACTERIZATION; EXPERIMENTAL CONDITIONS; INNATE IMMUNE SYSTEMS; LISTERIA MONOCYTOGENES; PHYSIOLOGICAL FUNCTIONS; SELF ASSEMBLY PROCESS;

SELF ASSEMBLY;

ALPHA DEFENSIN; ALPHA DEFENSIN 6; MUTANT PROTEIN; OLIGOMER; UNCLASSIFIED DRUG; ALPHA-DEFENSIN 6, HUMAN; ANTIINFECTIVE AGENT;

ANTIBACTERIAL ACTIVITY; ANTIGEN ANTIBODY REACTION; ARTICLE; BIOASSAY; BIOLOGICAL ACTIVITY; CELL CULTURE; CONTROLLED STUDY; ESCHERICHIA COLI; FIBER; GENE OVEREXPRESSION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOST RESISTANCE; HUMAN; HUMAN CELL; HYDROPHOBICITY; INNATE IMMUNITY; INTESTINE FLORA; LISTERIA MONOCYTOGENES; MAMMAL CELL; MOLECULAR PATHOLOGY; MOLECULAR PROBE; MUTATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; TRANSMISSION ELECTRON MICROSCOPY; AMINO ACID SEQUENCE; BACTERIAL INFECTIONS; BACTERIUM; CELL LINE; CHEMICAL PHENOMENA; CHEMISTRY; IMMUNOLOGY; LISTERIOSIS; MOLECULAR GENETICS;

ALPHA-DEFENSINS; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; CELL LINE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNITY, INNATE; LISTERIA MONOCYTOGENES; LISTERIOSIS; MOLECULAR SEQUENCE DATA;

EID: 84921279602     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja5057906     Document Type: Article

References (48)

1. Zhao, L.; Lu, W. Curr. Opin. Hematol. 2014, 21, 37-42.
2. Hazlett, L.; Wu, M. Cell Tissue Res. 2011, 343, 175-188.
3. Lehrer, R. I.; Lu, W. Immunol. Rev. 2012, 245, 84-112.
4. Doss, M.; White, M. R.; Tecle, T.; Hartshorn, K. L. J. Leukocyte Biol. 2010, 87, 79-92.
5. Ouellette, A. J. Cell. Mol. Life Sci. 2011, 68, 2215-2229.
6. Selsted, M. E.; Ouellette, A. J. Nat. Immunol. 2005, 6, 551-557.
7. Gabay, J. E.; Scott, R. W.; Campanelli, D.; Griffith, J.; Wilde, C.; Marra, M. N.; Seeger, M.; Nathan, C. F. Proc. Natl. Acad. Sci. U.S.A. 1989, 86, 5610-5614.
8. Wilde, C.; Gabay, J. E.; Marra, M. N.; Snable, J. L.; Scott, R. W. J. Biol. Chem. 1989, 264, 11200-11203.
9. Mackewicz, C. E.; Yuan, J.; Tran, P.; Diaz, L.; Mack, E.; Selsted, M. E.; Levy, J. A. AIDS 2003, 17, F23-F32.
10. Chalifour, A.; Jeannin, P.; Gauchat, J.-F.; Blaecke, A.; Malissard, M.; N'Guyen, T.; Thieblemont, N.; Delneste, Y. Blood 2004, 104,1778-1783.
11. Jones, D. E.; Bevins, C. L. J. Biol. Chem. 1992, 267, 23216-23225.
12. Jones, D. E.; Bevins, C. L. FEBS Lett. 1993, 315, 187-192.
13. Mallow, E. B.; Harris, A.; Salzman, N.; Russell, J. P.; DeBerardinis, R. J.; Ruchelli, E.; Bevins, C. L. J. Biol. Chem. 1996,271, 4038-4045.
14. Porter, E. M.; Liu, L.; Oren, A.; Anton, P. A.; Ganz, T. Infect. Immun. 1997, 65, 2389-2395.
15. Porter, E. M.; Bevins, C. L.; Ghosh, D.; Ganz, T. Cell. Mol. Life Sci. 2002, 59, 156-170.
16. Clevers, H. C.; Bevins, C. L. Annu. Rev. Physiol. 2013, 75, 289-311.
17. Wei, G.; de Leeuw, E.; Pazgier, M.; Yuan, W.; Zou, G.; Wang, J.; Ericksen, B.; Lu, W.-Y.; Lehrer, R. I.; Lu, W. J. Biol. Chem. 2009, 284,29180-29192.
18. Hill, C. P.; Yee, J.; Selsted, M. E.; Eisenberg, D. Science 1991, 251, 1481-1485.
19. Szyk, A.; Wu, Z.; Tucker, K.; Yang, D.; Lu, W.; Lubkowski, J. Protein Sci. 2006, 15, 2749-2760.
20. Wommack, A. J.; Robson, S. A.; Wanniarachchi, Y. A.; Wan, A.; Turner, C. J.; Wagner, G.; Nolan, E. M. Biochemistry 2012, 51, 9624-9637.
21. Chu, H.; Pazgier, M.; Jung, G.; Nuccio, S.-P.; Castillo, P. A.; de Jong, M. F.; Winter, M. G.; Winter, S. E.; Wehkamp, J.; Shen, B.; Salzman, N. H.; Underwood, M. A.; Tsolis, R. M.; Young, G. M.; Lu, W.; Lehrer, R. I.; Bäumler, A. J.; Bevins, C. L. Science 2012, 337, 477-481.
22. Ericksen, B.; Wu, Z.; Lu, W.; Lehrer, R. I. Antimicrob. Agents Chemother. 2005, 49, 269-275.
23. Porter, E. M.; van Dam, E.; Valore, E. V.; Ganz, T. Infect. Immun. 1997, 65, 2396-2401.
24. Salzman, N. H.; Ghosh, D.; Huttner, K. M.; Paterson, Y.; Bevins, C. L. Nature 2003, 442, 522-526.
25. Rajabi, M.; Ericksen, B.; Wu, X.; de Leeuw, E.; Zhao, L.; Pazgier, M.; Lu, W. J. Biol. Chem. 2012, 287, 21615-21627.
26. Pazgier, M.; Wei, G.; Ericksen, B.; Jung, G.; Wu, Z.; de Leeuw, E.; Yuan, W.; Szmacinski, H.; Lu, W.-Y.; Lubkowski, J.; Lehrer, R. I.; Lu, W. J. Biol. Chem. 2012, 287, 8944-8953.
27. Gounder, A. P.; Weins, M. E.; Wilson, S. S.; Lu, W.; Smith, J. G. J. Biol. Chem. 2012, 287, 24554-24562.
28. Tai, K. P.; Le, V. V.; Selsted, M. E.; Ouellette, A. J. Infect. Immun. 2014, 82, 2195-2202.
29. Wanniarachchi, Y. A.; Kaczmarek, P.; Wan, A.; Nolan, E. M. Biochemistry 2011, 50, 8005-8017.
30. Liu, L.; Ganz, T. Blood 1995, 85, 1095-1103.
31. Valore, E. V.; Ganz, T. Blood 1992, 79, 1538-1544.
32. Ghosh, D.; Porter, E.; Shen, B.; Lee, S. K.; Wilk, D.; Drazba, J.; Yadav, S. P.; Crabb, J. W.; Ganz, T.; Bevins, C. L. Nature 2002, 3, 583-590.
33. Ortega, A.; Amorós, D.; García de la Torre, J. G. Biophys. J. 2011, 101, 892-898.
34. Cossart, P.; Pizarro-Cerdá, J.; Lecuit, M. Trends Cell Biol. 2003, 13, 23-31.
35. Vivant, A.-L.; Garmyn, D.; Piveteau, P. Front. Cell. Infect. Microbiol. 2013, 3, 1-10.
36. Tanford, C. Science 1978, 200, 1012-1018.
37. Doig, A. J.; Williams, D. H. J. Mol. Biol. 1991, 217, 389-398.
38. Krishnan, A.; Cha, P.; Liu, Y.-H.; Allara, D.; Vogler, E. A. Biomaterials 2006, 27, 3187-3194.
39. Wurth, C.; Guimard, N. K.; Hecht, M. H. J. Mol. Biol. 2002, 319, 1279-1290.
40. Kim, W.; Hecht, M. H. J. Mol. Biol. 2008, 377, 565-574.
41. Giasson, B. I.; Murray, I. V. J.; Trojanowski, J. Q.; Lee, V. M.-Y. J. Biol. Chem. 2001, 276, 2380-2386.
42. Chiti, F.; Dobson, C. M. Annu. Rev. Biochem. 2006, 75, 333-366.
43. Wu, Z.; Ericksen, B.; Tucker, K.; Lubkowski, J.; Lu, W. J. Peptides Res. 2004, 64, 118-125.
44. Laue, M.; Shah, B. D.; Ridgeway, T. M.; Pelletier, S. L. Analytical Ultracentrifugation in Biochemistry and Polymer Science; Harding, S., Rowe, A., Eds.; Royal Society of Chemistry: Cambridge, U.K., 1992; pp 90-125.
45. Schuck, P. Anal. Biochem. 2003, 320, 104-124.
46. Philo, J. S. Anal. Biochem. 2000, 279, 151-163.
47. Jaradat, Z. W.; Bhunia, A. K. Appl. Environ. Microbiol. 2003, 69, 3640-3645.
48. Tang, P.; Foubister, V.; Pucciarelli, M. G.; Finlay, B. B. J. Microbiol. Methods 1993, 18, 227-240.