-
1
-
-
83655193502
-
α-Defensins in human innate immunity
-
Lehrer, R. I., and Lu, W. (2012) α-Defensins in human innate immunity. Immunol. Rev. 245, 84-112
-
(2012)
Immunol. Rev.
, vol.245
, pp. 84-112
-
-
Lehrer, R.I.1
Lu, W.2
-
2
-
-
33745698864
-
Defensins in innate antiviral immunity
-
Klotman, M. E., and Chang, T. L. (2006) Defensins in innate antiviral immunity. Nat. Rev. Immunol. 6, 447-456
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 447-456
-
-
Klotman, M.E.1
Chang, T.L.2
-
3
-
-
31944451136
-
Human α-defensins block papillomavirus infection
-
DOI 10.1073/pnas.0508033103
-
Buck, C. B., Day, P. M., Thompson, C. D., Lubkowski, J., Lu, W., Lowy, D. R., and Schiller, J. T. (2006) Human α-defensins block papillomavirus infection. Proc. Natl. Acad. Sci. U.S.A. 103, 1516-1521 (Pubitemid 43191197)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.5
, pp. 1516-1521
-
-
Buck, C.B.1
Day, P.M.2
Thompson, C.D.3
Lubkowski, J.4
Lu, W.5
Lowy, D.R.6
Schiller, J.T.7
-
4
-
-
57649178354
-
Human α-defensins inhibit BK virus infection by aggregating virions and blocking binding to host cells
-
Dugan, A. S., Maginnis, M. S., Jordan, J. A., Gasparovic, M. L., Manley, K., Page, R., Williams, G., Porter, E., O'Hara, B. A., and Atwood, W. J. (2008) Human α-defensins inhibit BK virus infection by aggregating virions and blocking binding to host cells. J. Biol. Chem. 283, 31125-31132
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31125-31132
-
-
Dugan, A.S.1
Maginnis, M.S.2
Jordan, J.A.3
Gasparovic, M.L.4
Manley, K.5
Page, R.6
Williams, G.7
Porter, E.8
O'Hara, B.A.9
Atwood, W.J.10
-
5
-
-
77954682175
-
Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization
-
Smith, J. G., Silvestry, M., Lindert, S., Lu, W., Nemerow, G. R., and Stewart, P. L. (2010) Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization. PLoS Pathog. 6, e1000959
-
(2010)
PLoS Pathog.
, vol.6
-
-
Smith, J.G.1
Silvestry, M.2
Lindert, S.3
Lu, W.4
Nemerow, G.R.5
Stewart, P.L.6
-
6
-
-
38049030654
-
Mechanism of adenovirus neutralization by human α-defensins
-
Smith, J. G., and Nemerow, G. R. (2008) Mechanism of adenovirus neutralization by human α-defensins. Cell Host Microbe 3, 11-19
-
(2008)
Cell Host Microbe
, vol.3
, pp. 11-19
-
-
Smith, J.G.1
Nemerow, G.R.2
-
7
-
-
77950470139
-
Direct evidence from single-cell analysis that human α-defensins block adenovirus uncoating to neutralize infection
-
Nguyen, E. K., Nemerow, G. R., and Smith, J. G. (2010) Direct evidence from single-cell analysis that human α-defensins block adenovirus uncoating to neutralize infection. J. Virol. 84, 4041-4049
-
(2010)
J. Virol.
, vol.84
, pp. 4041-4049
-
-
Nguyen, E.K.1
Nemerow, G.R.2
Smith, J.G.3
-
8
-
-
77952356835
-
Trp-26 imparts functional versatility to human α-defensin HNP1
-
Wei, G., Pazgier, M., de Leeuw, E., Rajabi, M., Li, J., Zou, G., Jung, G., Yuan, W., Lu, W. Y., Lehrer, R. I., and Lu, W. (2010) Trp-26 imparts functional versatility to human α-defensin HNP1. J. Biol. Chem. 285, 16275-16285
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 16275-16285
-
-
Wei, G.1
Pazgier, M.2
De Leeuw, E.3
Rajabi, M.4
Li, J.5
Zou, G.6
Jung, G.7
Yuan, W.8
Lu, W.Y.9
Lehrer, R.I.10
Lu, W.11
-
9
-
-
67849115958
-
Selective arginines are important for the antibacterial activity and host cell interaction of human α-defensin 5
-
de Leeuw, E., Rajabi, M., Zou, G., Pazgier, M., and Lu, W. (2009) Selective arginines are important for the antibacterial activity and host cell interaction of human α-defensin 5. FEBS Lett. 583, 2507-2512
-
(2009)
FEBS Lett.
, vol.583
, pp. 2507-2512
-
-
De Leeuw, E.1
Rajabi, M.2
Zou, G.3
Pazgier, M.4
Lu, W.5
-
10
-
-
34547120485
-
Toward understanding the cationicity of defensins: Arg and Lys versus their noncoded analogs
-
DOI 10.1074/jbc.M611003200
-
Zou, G., de Leeuw, E., Li, C., Pazgier, M., Li, C., Zeng, P., Lu, W. Y., Lubkowski, J., and Lu, W. (2007) Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs. J. Biol. Chem. 282, 19653-19665 (Pubitemid 47100066)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.27
, pp. 19653-19665
-
-
Zou, G.1
De Leeuw, E.2
Li, C.3
Pazgier, M.4
Li, C.5
Zeng, P.6
Lu, W.-Y.7
Lubkowski, J.8
Lu, W.9
-
11
-
-
70350461418
-
Electropositive charge in α-defensin bactericidal activity: Functional effects of Lys-for-Arg substitutions vary with the peptide primary structure
-
Llenado, R. A., Weeks, C. S., Cocco, M. J., and Ouellette, A. J. (2009) Electropositive charge in α-defensin bactericidal activity: functional effects of Lys-for-Arg substitutions vary with the peptide primary structure. Infect. Immun. 77, 5035-5043
-
(2009)
Infect. Immun.
, vol.77
, pp. 5035-5043
-
-
Llenado, R.A.1
Weeks, C.S.2
Cocco, M.J.3
Ouellette, A.J.4
-
12
-
-
84862679509
-
Functional determinants of human enteric α-defensin HD5: Crucial role for hydrophobicity at dimer interface
-
Rajabi, M., Ericksen, B., Wu, X., de Leeuw, E., Zhao, L., Pazgier, M., and Lu, W. (2012) Functional determinants of human enteric α-defensin HD5: Crucial role for hydrophobicity at dimer interface. J. Biol. Chem. 287, 21615-21627
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 21615-21627
-
-
Rajabi, M.1
Ericksen, B.2
Wu, X.3
De Leeuw, E.4
Zhao, L.5
Pazgier, M.6
Lu, W.7
-
13
-
-
84858591438
-
Sometimes it takes two to tango: Contributions of dimerization to functions of human α-defensin HNP1 peptide
-
Pazgier, M., Wei, G., Ericksen, B., Jung, G., Wu, Z., de Leeuw, E., Yuan, W., Szmacinski, H., Lu, W. Y., Lubkowski, J., Lehrer, R. I., and Lu, W. (2012) Sometimes it takes two to tango: Contributions of dimerization to functions of human α-defensin HNP1 peptide. J. Biol. Chem. 287, 8944-8953
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 8944-8953
-
-
Pazgier, M.1
Wei, G.2
Ericksen, B.3
Jung, G.4
Wu, Z.5
De Leeuw, E.6
Yuan, W.7
Szmacinski, H.8
Lu, W.Y.9
Lubkowski, J.10
Lehrer, R.I.11
Lu, W.12
-
14
-
-
68949094007
-
Multivalent binding of carbohydrates by the human alpha-defensin, HD5
-
Lehrer, R. I., Jung, G., Ruchala, P., Andre, S., Gabius, H. J., and Lu, W. (2009) Multivalent binding of carbohydrates by the human alpha-defensin, HD5. J. Immunol. 183, 480-490
-
(2009)
J. Immunol.
, vol.183
, pp. 480-490
-
-
Lehrer, R.I.1
Jung, G.2
Ruchala, P.3
Andre, S.4
Gabius, H.J.5
Lu, W.6
-
15
-
-
0346688642
-
Efficient Intracellular Assembly of Papillomaviral Vectors
-
DOI 10.1128/JVI.78.2.751-757.2004
-
Buck, C. B., Pastrana, D. V., Lowy, D. R., and Schiller, J. T. (2004) Efficient intracellular assembly of papillomaviral vectors. J. Virol. 78, 751-757 (Pubitemid 38067597)
-
(2004)
Journal of Virology
, vol.78
, Issue.2
, pp. 751-757
-
-
Buck, C.B.1
Pastrana, D.V.2
Lowy, D.R.3
Schiller, J.T.4
-
16
-
-
13944260775
-
Maturation of papillomavirus capsids
-
DOI 10.1128/JVI.79.5.2839-2846.2005
-
Buck, C. B., Thompson, C. D., Pang, Y. Y., Lowy, D. R., and Schiller, J. T. (2005) Maturation of papillomavirus capsids. J. Virol. 79, 2839-2846 (Pubitemid 40270562)
-
(2005)
Journal of Virology
, vol.79
, Issue.5
, pp. 2839-2846
-
-
Buck, C.B.1
Thompson, C.D.2
Pang, Y.-Y.S.3
Lowy, D.R.4
Schiller, J.T.5
-
17
-
-
4444356630
-
Synthesis and characterization of human α-defensins 4-6
-
DOI 10.1111/j.1399-3011.2004.00179.x
-
Wu, Z., Ericksen, B., Tucker, K., Lubkowski, J., and Lu, W. (2004) Synthesis and characterization of human α-defensins 4-6. J. Pept. Res. 64, 118-125 (Pubitemid 39209087)
-
(2004)
Journal of Peptide Research
, vol.64
, Issue.3
, pp. 118-125
-
-
Wu, Z.1
Ericksen, B.2
Tucker, K.3
Lubkowski, J.4
Lu, W.5
-
18
-
-
0028871804
-
How to measure and predict the molar absorption coefficient of a protein
-
Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., and Gray, T. (1995) How to measure and predict the molar absorption coefficient of a protein. Protein Sci. 4, 2411-2423
-
(1995)
Protein Sci.
, vol.4
, pp. 2411-2423
-
-
Pace, C.N.1
Vajdos, F.2
Fee, L.3
Grimsley, G.4
Gray, T.5
-
19
-
-
0036079594
-
Paneth cell trypsin is the processing enzyme for human defensin-5
-
DOI 10.1038/ni797
-
Ghosh, D., Porter, E., Shen, B., Lee, S. K., Wilk, D., Drazba, J., Yadav, S. P., Crabb, J. W., Ganz, T., and Bevins, C. L. (2002) Paneth cell trypsin is the processing enzyme for human defensin-5. Nat Immunol 3, 583-590 (Pubitemid 34662312)
-
(2002)
Nature Immunology
, vol.3
, Issue.6
, pp. 583-590
-
-
Ghosh, D.1
Porter, E.2
Shen, B.3
Lee, S.K.4
Wilk, D.5
Drazba, J.6
Yadav, S.P.7
Crabb, J.W.8
Ganz, T.9
Bevins, C.L.10
-
20
-
-
0034252293
-
Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria
-
Ayabe, T., Satchell, D. P., Wilson, C. L., Parks, W. C., Selsted, M. E., and Ouellette, A. J. (2000) Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria. Nat. Immunol. 1, 113-118
-
(2000)
Nat. Immunol.
, vol.1
, pp. 113-118
-
-
Ayabe, T.1
Satchell, D.P.2
Wilson, C.L.3
Parks, W.C.4
Selsted, M.E.5
Ouellette, A.J.6
-
21
-
-
52049114697
-
The conserved salt bridge in human α-defensin 5 is required for its precursor processing and proteolytic stability
-
Rajabi, M., de Leeuw, E., Pazgier, M., Li, J., Lubkowski, J., and Lu, W. (2008) The conserved salt bridge in human α-defensin 5 is required for its precursor processing and proteolytic stability. J. Biol. Chem. 283, 21509-21518
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 21509-21518
-
-
Rajabi, M.1
De Leeuw, E.2
Pazgier, M.3
Li, J.4
Lubkowski, J.5
Lu, W.6
-
22
-
-
33751545243
-
Crystal structures of human α-defensins HNP4, HD5, and HD6
-
DOI 10.1110/ps.062336606
-
Szyk, A., Wu, Z., Tucker, K., Yang, D., Lu, W., and Lubkowski, J. (2006) Crystal structures of human α-defensins HNP4, HD5, and HD6. Protein Sci 15, 2749-2760 (Pubitemid 44833756)
-
(2006)
Protein Science
, vol.15
, Issue.12
, pp. 2749-2760
-
-
Szyk, A.1
Wu, Z.2
Tucker, K.3
Yang, D.4
Lu, W.5
Lubkowski, J.6
-
23
-
-
79958248102
-
Human defensins 5 and 6 enhance HIV-1 infectivity through promoting HIV attachment
-
Rapista, A., Ding, J., Benito, B., Lo, Y. T., Neiditch, M. B., Lu, W., and Chang, T. L. (2011) Human defensins 5 and 6 enhance HIV-1 infectivity through promoting HIV attachment. Retrovirology 8, 45
-
(2011)
Retrovirology
, vol.8
, pp. 45
-
-
Rapista, A.1
Ding, J.2
Benito, B.3
Lo, Y.T.4
Neiditch, M.B.5
Lu, W.6
Chang, T.L.7
-
24
-
-
0028268676
-
A structural role for arginine in proteins: Multiple hydrogen bonds to backbone carbonyl oxygens
-
Borders, C. L., Jr., Broadwater, J. A., Bekeny, P. A., Salmon, J. E., Lee, A. S., Eldridge, A. M., and Pett, V. B. (1994) A structural role for arginine in proteins: Multiple hydrogen bonds to backbone carbonyl oxygens. Protein Sci. 3, 541-548 (Pubitemid 24136359)
-
(1994)
Protein Science
, vol.3
, Issue.4
, pp. 541-548
-
-
Borders Jr., C.L.1
Broadwater, J.A.2
Bekeny, P.A.3
Salmon, J.E.4
Lee, A.S.5
Eldridge, A.M.6
Pett, V.B.7
-
25
-
-
0031008576
-
Hydrophobicity regained
-
Karplus, P. A. (1997) Hydrophobicity regained. Protein Sci. 6, 1302-1307
-
(1997)
Protein Sci.
, vol.6
, pp. 1302-1307
-
-
Karplus, P.A.1
-
26
-
-
16844373634
-
Identification of the glycosylation site of the adenovirus type 5 fiber protein
-
DOI 10.1021/bi047702b
-
Cauet, G., Strub, J. M., Leize, E., Wagner, E., Van Dorsselaer, A., and Lusky, M. (2005) Identification of the glycosylation site of the adenovirus type 5 fiber protein. Biochemistry 44, 5453-5460 (Pubitemid 40489984)
-
(2005)
Biochemistry
, vol.44
, Issue.14
, pp. 5453-5460
-
-
Cauet, G.1
Strub, J.-M.2
Leize, E.3
Wagner, E.4
Van Dorsselaer, A.5
Lusky, M.6
-
27
-
-
80053618537
-
The transduction of Coxsackie and adenovirus receptor-negative cells and protection against neutralizing antibodies by HPMA-co-oligolysine copolymer-coated adenovirus
-
Wang, C. H., Chan, L. W., Johnson, R. N., Chu, D. S., Shi, J., Schellinger, J. G., Lieber, A., and Pun, S. H. (2011) The transduction of Coxsackie and adenovirus receptor-negative cells and protection against neutralizing antibodies by HPMA-co-oligolysine copolymer-coated adenovirus. Biomaterials 32, 9536-9545
-
(2011)
Biomaterials
, vol.32
, pp. 9536-9545
-
-
Wang, C.H.1
Chan, L.W.2
Johnson, R.N.3
Chu, D.S.4
Shi, J.5
Schellinger, J.G.6
Lieber, A.7
Pun, S.H.8
-
28
-
-
14644425916
-
Dual role of α-defensin-1 in anti-HIV-1 innate immunity
-
DOI 10.1172/JCI200521948
-
Chang, T. L., Vargas, J., Jr., DelPortillo, A., and Klotman, M. E. (2005) Dual role of α-defensin-1 in anti-HIV-1 innate immunity. J. Clin. Invest. 115, 765-773 (Pubitemid 40322253)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.3
, pp. 765-773
-
-
Chang, T.L.1
Vargas Jr., J.2
DelPortillo, A.3
Klotman, M.E.4
|