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Volumn 20, Issue JULY-DECEMBER 2014, 2014, Pages 490-502

Binge alcohol consumption aggravates oxidative stress and promotes pathogenesis of NASH from obesity-induced simple steatosis

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 2E1; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; INSULIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; 4-HYDROXY-2-NONENAL; ALDEHYDE; TUMOR NECROSIS FACTOR;

EID: 84921061696     PISSN: 10761551     EISSN: 15283658     Source Type: Journal    
DOI: 10.2119/molmed.2014.00048     Document Type: Article
Times cited : (40)

References (50)
  • 1
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • Ludwig J, Viggiano TR, McGill DB, Oh BJ. (1980) Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin. Proc.55:434–8.
    • (1980) Mayo Clin. Proc. , vol.55 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3    Oh, B.J.4
  • 2
    • 0036829092 scopus 로고    scopus 로고
    • AGA technical review in nonalcoholic fatty liver disease
    • Sanyal AJ. (2002) AGA technical review in nonalcoholic fatty liver disease. Gastroenterology. 123:1705–25.
    • (2002) Gastroenterology , vol.123 , pp. 1705-1725
    • Sanyal, A.J.1
  • 3
    • 0033068723 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Younossi ZM. (1999) Nonalcoholic fatty liver disease. Curr. Gastroenterol. Rep.1:57–62.
    • (1999) Curr. Gastroenterol. Rep. , vol.1 , pp. 57-62
    • Younossi, Z.M.1
  • 4
    • 0028875908 scopus 로고
    • The natural history of nonalcoholic fatty liver: A follow-up study
    • Teli MR, James OF, Burt AD, Bennett MK, Day CP. (1995) The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology. 22:1714–9.
    • (1995) Hepatology , vol.22 , pp. 1714-1719
    • Teli, M.R.1    James, O.F.2    Burt, A.D.3    Bennett, M.K.4    Day, C.P.5
  • 5
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two “hits”?
    • Day CP, James OFW. (1998) Steatohepatitis: a tale of two “hits”? Gastroenterology. 114:842–5.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.2
  • 6
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning JD, Horton JD. (2004) Molecular mediators of hepatic steatosis and liver injury. J. Clin. Invest.114:147–52.
    • (2004) J. Clin. Invest. , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 7
    • 0031761559 scopus 로고    scopus 로고
    • Diagnosis and interpretation of steatosis and steatohepatitis
    • Burt AD, Mutton A, Day CP. (1998) Diagnosis and interpretation of steatosis and steatohepatitis. Semin. Diagn. Pathol.15:246–58.
    • (1998) Semin. Diagn. Pathol. , vol.15 , pp. 246-258
    • Burt, A.D.1    Mutton, A.2    Day, C.P.3
  • 8
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
    • Matteoni CA, et al.(1999) Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology. 116:1413–9.
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1
  • 9
    • 0035078484 scopus 로고    scopus 로고
    • Etiopathogenesis of nonalcoholic steatohepatitis
    • Chitturi S, Farrell GC. (2001) Etiopathogenesis of nonalcoholic steatohepatitis. Semin. Liver. Dis.21:27–41.
    • (2001) Semin. Liver. Dis. , vol.21 , pp. 27-41
    • Chitturi, S.1    Farrell, G.C.2
  • 10
    • 65749115425 scopus 로고    scopus 로고
    • Non alcoholic fatty liver disease and metabolic syndrome
    • Paschos P, Paletas K. (2009) Non alcoholic fatty liver disease and metabolic syndrome. Hippokratia. 13:9–19.
    • (2009) Hippokratia , vol.13 , pp. 9-19
    • Paschos, P.1    Paletas, K.2
  • 11
    • 82455167937 scopus 로고    scopus 로고
    • An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice
    • Mandrekar P, Ambade A, Lim A, Szabo G, Catalano D. (2011) An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice. Hepatology. 54:2185–97.
    • (2011) Hepatology , vol.54 , pp. 2185-2197
    • Mandrekar, P.1    Ambade, A.2    Lim, A.3    Szabo, G.4    Catalano, D.5
  • 12
    • 0036163759 scopus 로고    scopus 로고
    • Mechanisms of hepatotoxicity
    • Jaeschke H, et al.(2002) Mechanisms of hepatotoxicity. Toxicol. Sci.65:166–76.
    • (2002) Toxicol. Sci. , vol.65 , pp. 166-176
    • Jaeschke, H.1
  • 13
    • 0025805616 scopus 로고
    • Induction of cytochrome P450IIE1 in the obese overfed rat
    • Raucy JL, et al.(1991) Induction of cytochrome P450IIE1 in the obese overfed rat. Mol. Pharmacol.39:275–80.
    • (1991) Mol. Pharmacol. , vol.39 , pp. 275-280
    • Raucy, J.L.1
  • 14
    • 0034092716 scopus 로고    scopus 로고
    • CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
    • Leclercq IA, et al.(2000) CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J. Clin. Invest.105:1067–75.
    • (2000) J. Clin. Invest. , vol.105 , pp. 1067-1075
    • Leclercq, I.A.1
  • 15
    • 0034235208 scopus 로고    scopus 로고
    • Metabolic and nutritional considerations in nonalcoholic fatty liver
    • Fong DG, Nehra V, Lindor KD, Buchman AL. (2000) Metabolic and nutritional considerations in nonalcoholic fatty liver. Hepatology. 32:3–10.
    • (2000) Hepatology , vol.32 , pp. 3-10
    • Fong, D.G.1    Nehra, V.2    Lindor, K.D.3    Buchman, A.L.4
  • 16
    • 39149123560 scopus 로고    scopus 로고
    • CYP2E1 and oxidative liver injury by alcohol
    • Lu Y, Cederbaum AI. CYP2E1 and oxidative liver injury by alcohol. (2008) Free Radic. Biol. Med.44:723–38.
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 723-738
    • Lu, Y.1    Cederbaum, A.I.2
  • 17
    • 0027499273 scopus 로고
    • Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA
    • Takahashi T, Lasker JM, Rosman AS, Lieber CS. (1993) Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA. Hepatology. 17:236–45.
    • (1993) Hepatology , vol.17 , pp. 236-245
    • Takahashi, T.1    Lasker, J.M.2    Rosman, A.S.3    Lieber, C.S.4
  • 18
    • 0024378451 scopus 로고
    • The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver
    • Tsutsumi M, Lasker JM, Shimizu M, Rosman AS, Lieber CS. (1989) The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver. Hepatology. 10:437–46.
    • (1989) Hepatology , vol.10 , pp. 437-446
    • Tsutsumi, M.1    Lasker, J.M.2    Shimizu, M.3    Rosman, A.S.4    Lieber, C.S.5
  • 19
  • 20
    • 0023656593 scopus 로고
    • Responses to insulin by two forms of rat hepatic microsomal cytochrome P-450 that undergo major (RLM6) and minor (RLM5b) elevations in diabetes
    • Favreau LV, Malchoff DM, Mole JE, Schenkman JB. (1987) Responses to insulin by two forms of rat hepatic microsomal cytochrome P-450 that undergo major (RLM6) and minor (RLM5b) elevations in diabetes. J. Biol. Chem.262:14319–26.
    • (1987) J. Biol. Chem. , vol.262 , pp. 14319-14326
    • Favreau, L.V.1    Malchoff, D.M.2    Mole, J.E.3    Schenkman, J.B.4
  • 21
    • 10444229539 scopus 로고    scopus 로고
    • Role of cytochromes P450 in chemical toxicity and oxidative stress: Studies with CYP2E1
    • Gonzalez FJ. (2005) Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. Mutat. Res.569:101–10.
    • (2005) Mutat. Res. , vol.569 , pp. 101-110
    • Gonzalez, F.J.1
  • 22
    • 0029082892 scopus 로고
    • Insulin resistance in skeletal muscle of the male Otsuka Long-Evans Tokushima Fatty rat, a new model of NIDDM
    • Sato T, Asahi Y, Toide K, Nakayama N. (1995) Insulin resistance in skeletal muscle of the male Otsuka Long-Evans Tokushima Fatty rat, a new model of NIDDM. Diabetologia. 38:1033–41.
    • (1995) Diabetologia , vol.38 , pp. 1033-1041
    • Sato, T.1    Asahi, Y.2    Toide, K.3    Nakayama, N.4
  • 23
    • 51749108218 scopus 로고    scopus 로고
    • Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats
    • Rector RS, et al.(2008) Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. J. Physiol.586:4241–9.
    • (2008) J. Physiol. , vol.586 , pp. 4241-4249
    • Rector, R.S.1
  • 24
    • 33846253661 scopus 로고    scopus 로고
    • Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis
    • Ota T, et al.(2007) Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. Gastroenterology. 132:282–93.
    • (2007) Gastroenterology , vol.132 , pp. 282-293
    • Ota, T.1
  • 25
    • 33746268381 scopus 로고    scopus 로고
    • Hyperphagia and obesity of OLETF rats lacking CCK1 receptors: Developmental aspects
    • Moran TH, Bi S. (2006) Hyperphagia and obesity of OLETF rats lacking CCK1 receptors: developmental aspects. Dev. Psychobiol.48:360–7.
    • (2006) Dev. Psychobiol. , vol.48 , pp. 360-367
    • Moran, T.H.1    Bi, S.2
  • 26
    • 0003633755 scopus 로고    scopus 로고
    • Institute of Laboratory Animal Resources; Commission on Life Sciences; National Research Council, DC): National Academy Press
    • Institute of Laboratory Animal Resources; Commission on Life Sciences; National Research Council. (1996) Guide for the Care and Use of Laboratory Animals. Washington (DC): National Academy Press.
    • (1996) Guide for the Care and Use of Laboratory Animals
  • 27
    • 0017119793 scopus 로고
    • Gammaglutamyl- 3-carboxy-14-nitroanilide: The substrate of choice for routine determinations of gammaglutamyl- transferase activity in serum?
    • Theodorsen L, Stromme JH. (1976) Gammaglutamyl- 3-carboxy-14-nitroanilide: the substrate of choice for routine determinations of gammaglutamyl- transferase activity in serum? Clin. Chim. Acta.72:205–10.
    • (1976) Clin. Chim. Acta. , vol.72 , pp. 205-210
    • Theodorsen, L.1    Stromme, J.H.2
  • 28
    • 0032752691 scopus 로고    scopus 로고
    • Endpoint colorimetric method for assaying total cholesterol in serum with cholesterol dehydrogenase
    • Kayamori Y, Hatsuyama H, Tsujioka T, Nasu M, Katayama Y. (1999) Endpoint colorimetric method for assaying total cholesterol in serum with cholesterol dehydrogenase. Clin. Chem.45:2158–63.
    • (1999) Clin. Chem. , vol.45 , pp. 2158-2163
    • Kayamori, Y.1    Hatsuyama, H.2    Tsujioka, T.3    Nasu, M.4    Katayama, Y.5
  • 29
    • 0015847114 scopus 로고
    • Quantitative determination of serum triglycerides by the use of enzymes
    • Bucolo G, David H. (1973) Quantitative determination of serum triglycerides by the use of enzymes. Clin. Chem.19:476–82.
    • (1973) Clin. Chem. , vol.19 , pp. 476-482
    • Bucolo, G.1    David, H.2
  • 30
    • 33846105545 scopus 로고    scopus 로고
    • Resistance to leptin action is the major determinant of hepatic triglyceride accumulation in vivo
    • Fishman S, et al.(2007) Resistance to leptin action is the major determinant of hepatic triglyceride accumulation in vivo. FASEB J. 21:53–60.
    • (2007) FASEB J , vol.21 , pp. 53-60
    • Fishman, S.1
  • 31
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, et al.(2005) Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 41:1313–21.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1
  • 32
    • 84859164281 scopus 로고    scopus 로고
    • Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Tolllike receptor activation
    • Roth CL, et al.(2012) Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Tolllike receptor activation. Hepatology. 55:1103–11.
    • (2012) Hepatology , vol.55 , pp. 1103-1111
    • Roth, C.L.1
  • 33
    • 36048976016 scopus 로고    scopus 로고
    • M-30 and 4HNE are sequestered in different aggresomes in the same hepatocytes
    • Amidi F, et al.(2007) M-30 and 4HNE are sequestered in different aggresomes in the same hepatocytes. Exp. Mol. Pathol.83:296–300.
    • (2007) Exp. Mol. Pathol. , vol.83 , pp. 296-300
    • Amidi, F.1
  • 34
    • 0346689992 scopus 로고    scopus 로고
    • Overweight and obesity, hepatic steatosis, and progression of chronic hepatitis C: A retrospective study on a large cohort of patients in the United States
    • Hu KQ, et al.(2004) Overweight and obesity, hepatic steatosis, and progression of chronic hepatitis C: a retrospective study on a large cohort of patients in the United States. J. Hepatol.40:147–54.
    • (2004) J. Hepatol. , vol.40 , pp. 147-154
    • Hu, K.Q.1
  • 35
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • Farrell GC, Larter CZ. (2006) Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology. 43(2 Suppl 1):S99–112.
    • (2006) Hepatology , vol.43 , Issue.2 , pp. 99-112
    • Farrell, G.C.1    Larter, C.Z.2
  • 37
    • 18244387691 scopus 로고    scopus 로고
    • Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease
    • Tamura S, Shimomura I. (2005) Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease. J. Clin. Invest.115:1139–42.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1139-1142
    • Tamura, S.1    Shimomura, I.2
  • 39
    • 84893429347 scopus 로고    scopus 로고
    • Long term intake of 0.1% ethanol decreases serum adiponectin by suppressing PPARãexpression via p38 MAPK pathway
    • Tian C, et al.(2014) Long term intake of 0.1% ethanol decreases serum adiponectin by suppressing PPARã expression via p38 MAPK pathway. Food Chem. Toxicol.65:329–34.
    • (2014) Food Chem. Toxicol. , vol.65 , pp. 329-334
    • Tian, C.1
  • 40
    • 84856403628 scopus 로고    scopus 로고
    • Ethanol-induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes
    • Tang H, et al.(2012) Ethanol-induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes. Alcohol Clin. Exp. Res.36:214–22.
    • (2012) Alcohol Clin. Exp. Res. , vol.36 , pp. 214-222
    • Tang, H.1
  • 41
    • 80052213436 scopus 로고    scopus 로고
    • A peroxisome proliferatoractivated receptor gamma (PPARgamma)/PPARgamma coactivator 1beta autoregulatory loop in adipocyte mitochondrial function
    • Deng T, et al.(2011) A peroxisome proliferatoractivated receptor gamma (PPARgamma)/PPARgamma coactivator 1beta autoregulatory loop in adipocyte mitochondrial function. J. Biol. Chem.286:30723–31.
    • (2011) J. Biol. Chem. , vol.286 , pp. 30723-30731
    • Deng, T.1
  • 42
    • 0033867178 scopus 로고    scopus 로고
    • Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes
    • Moller DE. (2000) Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol. Metab.11:212–7.
    • (2000) Trends Endocrinol. Metab. , vol.11 , pp. 212-217
    • Moller, D.E.1
  • 43
    • 0012785395 scopus 로고    scopus 로고
    • Metformin reverses fatty liver disease in obese, leptin deficient mice
    • Lin HZ, Yang SQ, Kujhada F, Ronnet G, Diehl AM. (2000) Metformin reverses fatty liver disease in obese, leptin deficient mice. Nat. Med.6:998–1003.
    • (2000) Nat. Med. , vol.6 , pp. 998-1003
    • Lin, H.Z.1    Yang, S.Q.2    Kujhada, F.3    Ronnet, G.4    Diehl, A.M.5
  • 44
    • 0036165809 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease
    • Valenti L, et al.(2002) Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease. Gastroenterology. 122:274–80.
    • (2002) Gastroenterology , vol.122 , pp. 274-280
    • Valenti, L.1
  • 45
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
    • Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. (1997) Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature. 389:610–4.
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 46
    • 0345059393 scopus 로고    scopus 로고
    • Binge ethanol exposure increases liver injury in obese rats
    • Carmiel-Haggai M, Cederbaum AI, Nieto N. (2003) Binge ethanol exposure increases liver injury in obese rats. Gastroenterology. 125:1818–33.
    • (2003) Gastroenterology , vol.125 , pp. 1818-1833
    • Carmiel-Haggai, M.1    Cederbaum, A.I.2    Nieto, N.3
  • 47
    • 84885366143 scopus 로고    scopus 로고
    • CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis
    • Abdelmegeed MA, et al.(2013) CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis. Free Radic. Biol. Med.65:1238–45.
    • (2013) Free Radic. Biol. Med. , vol.65 , pp. 1238-1245
    • Abdelmegeed, M.A.1
  • 48
    • 84863987868 scopus 로고    scopus 로고
    • Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD)
    • Dunn W, et al.(2012) Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD). J. Hepatol.57:384–91.
    • (2012) J. Hepatol. , vol.57 , pp. 384-391
    • Dunn, W.1
  • 49
    • 46249090385 scopus 로고    scopus 로고
    • Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease
    • Dunn W, Xu R, Schwimmer JB. (2008) Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease. Hepatology.47:1947–54.
    • (2008) Hepatology , vol.47 , pp. 1947-1954
    • Dunn, W.1    Xu, R.2    Schwimmer, J.B.3
  • 50
    • 69549122913 scopus 로고    scopus 로고
    • Effects of light-to- moderate alcohol consumption on steatosis and steatohepatitis in severely obese patients
    • Cotrim HP, et al.(2009) Effects of light-to- moderate alcohol consumption on steatosis and steatohepatitis in severely obese patients. Eur. J. Gastroenterol. Hepatol.21:969–972.
    • (2009) Eur. J. Gastroenterol. Hepatol. , vol.21 , pp. 969-972
    • Cotrim, H.P.1


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